Solid-Phase Optical Sensing Techniques for Sensitive Virus Detection DOI Creative Commons
Elif Seymour,

Fulya Ekiz Kanık,

Sinem Diken Gür

et al.

Sensors, Journal Year: 2023, Volume and Issue: 23(11), P. 5018 - 5018

Published: May 24, 2023

Viral infections can pose a major threat to public health by causing serious illness, leading pandemics, and burdening healthcare systems. The global spread of such causes disruptions every aspect life including business, education, social life. Fast accurate diagnosis viral has significant implications for saving lives, preventing the diseases, minimizing economic damages. Polymerase chain reaction (PCR)-based techniques are commonly used detect viruses in clinic. However, PCR several drawbacks, as highlighted during recent COVID-19 pandemic, long processing times requirement sophisticated laboratory instruments. Therefore, there is an urgent need fast virus detection. For this purpose, variety biosensor systems being developed provide rapid, sensitive, high-throughput diagnostic platforms, enabling quick efficient control virus’s spread. Optical devices, particular, great interest due their advantages high sensitivity direct readout. current review discusses solid-phase optical sensing detection, fluorescence-based sensors, surface plasmon resonance (SPR), surface-enhanced Raman scattering (SERS), resonators, interferometry-based platforms. Then, we focus on interferometric our group, single-particle reflectance imaging sensor (SP-IRIS), which capability visualize single nanoparticles, demonstrate its application digital

Language: Английский

Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases DOI Creative Commons
Ece Ekşin, Arzum Erdem

Micromachines, Journal Year: 2023, Volume and Issue: 14(2), P. 295 - 295

Published: Jan. 23, 2023

Optical biosensors have many advantages over traditional analytical methods. They enable the identification of several biological and chemical compounds directly, instantly, without need labels. Their benefits include excellent specificity, sensitivity, compact size, low cost. In this review, main focus is placed on nucleic acid-based optical biosensor technologies, including colorimetric, fluorescence, surface plasmon resonance (SPR), Evanescent-Wave Optical, Fiber optic bioluminescent fibre. The fundamentals each type are briefly explained, particular emphasis has been achievements which gained in last decade field diagnosis infectious viral diseases. Concluding remarks concerning perspectives further developments discussed.

Language: Английский

Citations

17
Detection strategies of infectious diseases via peptide-based electrochemical biosensors DOI
Simge Balaban Hanoglu, Duygu Harmancı, Serap Evran

et al.

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 160, P. 108784 - 108784

Published: July 27, 2024

Language: Английский

Citations

8
Nanophotonic catheters: A lens into the body for biosensing and biomedical imaging DOI
Bakr Ahmed Taha,

Inas A. Al-Tahar,

Ali J. Addie

et al.

Applied Materials Today, Journal Year: 2024, Volume and Issue: 38, P. 102229 - 102229

Published: May 21, 2024

Language: Английский

Citations

7
Electrochemical Biosensor Based on Laser-Induced Graphene for COVID-19 Diagnosing: Rapid and Low-Cost Detection of SARS-CoV-2 Biomarker Antibodies DOI Creative Commons
Marcely Echeverria Oliveira, Bruno Vasconcellos Lopes, Jéssica Helisa Hautrive Rossato

et al.

Surfaces, Journal Year: 2022, Volume and Issue: 5(1), P. 187 - 201

Published: March 1, 2022

The severe acute respiratory syndrome originated by the new coronavirus (SARS-CoV-2) that emerged in late 2019, known to be a highly transmissible and pathogenic disease, has caused COVID-19 global pandemic outbreak. Thus, diagnostic devices help epidemiological public safety measures reduce undetected cases isolation of infected patients, addition significantly control population’s immune response vaccine, are required. To address negative issues clinical research, we developed Diagnostic on Chip platform based disposable electrochemical biosensor containing laser-induced graphene protein (SARS-CoV-2 specific antigen) for detection SARS-CoV-2 antibodies. biosensors were produced via direct laser writing using CO2 infrared cutting machine commercial polyimide sheets. presence antibodies reacting with K3[Fe(CN)6] redox indicator characteristic concentration-dependent signals, mean current values 9.6757 8.1812 µA reactive non-reactive samples, respectively, proving effectiveness testing samples serum from patients. is being expanded measured portable microcontrolled potentiostat applied as fast reliable monitoring mapping tool, aiming assess vaccinal population.

Language: Английский

Citations

26
Emerging Point-of-Care Optical Biosensing Technologies for Diagnostics of Microbial Infections DOI
Shalu Yadav, Arpana Parihar, Mohd. Abubakar Sadique

et al.

ACS Applied Optical Materials, Journal Year: 2023, Volume and Issue: 1(7), P. 1245 - 1262

Published: June 30, 2023

The surge of pathogenic illnesses is responsible for millions mortalities occurring in underdeveloped and developing countries. Different pathogens such as viruses, bacteria, fungi, protozoa are the causative agents fatalities. rapid proliferation diseases threatens entire human population possibly economy. Owing to time-consuming sophisticated laboratory setup, conventional diagnostic tools not sufficient detection microbial infections. To treat infections successfully, simple, fast, accurate, cost-effective great importance. Optical biosensors effective techniques highly sensitive, specific, multiplexed, easy-to-use determination In modern era, need efficacious point-of-care (POC) huge demand with prominence portability, high sensitivity, being user-friendly, having on-site ability. Currently, efforts have been made advancement POC optical through integration technical support like artificial intelligence, machine learning, internet-of-things, internet-of-medical-things (IoMT). These smart technique-incorporated advanced can fill gap between generation bioinformatics, large data analytics, clinical validation. Moreover, integrated will be beneficial understand progression diseases, authentication, assessment efficiency prescribed treatment.

Language: Английский

Citations

15
MXene-based biosensors for selective detection of pathogenic viruses and bacteria DOI
Serap Sezen, Atefeh Zarepour, Ali Zarrabi

et al.

Microchemical Journal, Journal Year: 2023, Volume and Issue: 193, P. 109258 - 109258

Published: Aug. 26, 2023

Language: Английский

Citations

14
The importance, benefits, and future of nanobiosensors for infectious diseases DOI

Th. S. Dhahi,

Alaa Kamal Yousif Dafhalla, Sawsan Ali Saad

et al.

Biotechnology and Applied Biochemistry, Journal Year: 2024, Volume and Issue: 71(2), P. 429 - 445

Published: Jan. 18, 2024

Abstract Infectious diseases, caused by pathogenic microorganisms such as bacteria, viruses, parasites, or fungi, are crucial for efficient disease management, reducing morbidity and mortality rates controlling spread. Traditional laboratory‐based diagnostic methods face challenges high costs, time consumption, a lack of trained personnel in resource‐poor settings. Diagnostic biosensors have gained momentum potential solution, offering advantages low cost, sensitivity, ease use, portability. Nanobiosensors promising tool detecting diagnosing infectious diseases coronavirus disease, human immunodeficiency virus, hepatitis. These sensors use nanostructured carbon nanotubes, graphene, nanoparticles to detect specific biomarkers pathogens. They operate through mechanisms like the lateral flow test platform, where sample containing biomarker pathogen is applied strip. If present, binds recognition probes on strip, indicating positive result. This binding event visualized colored line. review discusses importance, benefits, nanobiosensors diseases.

Language: Английский

Citations

5
Recent Advances of Optical Biosensors in Veterinary Medicine: Moving Towards the Point of Care Applications DOI
Niloufar Amin,

Ameneh Almasi,

Tuğba Özer

et al.

Current Topics in Medicinal Chemistry, Journal Year: 2023, Volume and Issue: 23(23), P. 2242 - 2265

Published: July 19, 2023

While food safety issues are attracting public concern due to their detrimental effects on human health, monitoring livestock health is urgently needed diagnose animal diseases at an early stage by applying proper treatments, controlling, and preventing outbreaks, particularly in resource- limited countries. In addition, unhealthy farms not only a threat but also lives. The available diagnostic techniques for the detection of key threats within both sectors require labor-intensive time-consuming experimental procedures sophisticated expensive instruments. To tackle this issue, optical biosensing strategies have been incorporated into point-of-care (POC) systems, offering real-time monitoring, field-deployable, low-cost devices, which help make on-the-spot decisions. This review aims discuss recent cutting-edge research POC platforms on-farm diagnosis on-site animal-derived food-borne contaminants, including pathogens, antibiotics, mycotoxins. Moreover, briefly presents basic knowledge various types biosensors development using strategies, nanomaterial combinations, enhance performance tests. expected scientists understand evolution challenges industry, benefiting global healthcare.

Language: Английский

Citations

11
Amelioration in nanobiosensors for the control of plant diseases: current status and future challenges DOI Creative Commons

Verinder Virk,

Himani Deepak,

Khushbu Taneja

et al.

Frontiers in Nanotechnology, Journal Year: 2024, Volume and Issue: 6

Published: March 27, 2024

The increase in global population has had a tremendous impact on sustainable agri-food practices. With the growth world population, various modern technologies are being utilized that more often result opening of opportunities agriculture and food sectors. Nanotechnology is used sectors for variety purposes, including enhancing flavor, pest/pathogen diagnosis, production, processing, storage, packaging, transportation agricultural products. Plant pathogenic microorganisms bacteria, viruses, fungi, nematodes have significant economy. In particular, advances nanotechnology, nanobiosensors, been detection plant diseases pathogens, evaluation examination infections caused by microorganisms, management and, thus, promotion security. Apart from diseases, nanobiosensors offer better production controlling physical, chemical, biological processes, thus improving safety This review outlines application nano-integrated

Language: Английский

Citations

4
Emerging nanophotonic biosensor technologies for virus detection DOI Creative Commons
Shivananju Bannur Nanjunda,

Venkatesh N. Seshadri,

Chitra Krishnan

et al.

Nanophotonics, Journal Year: 2022, Volume and Issue: 11(22), P. 5041 - 5059

Published: Dec. 1, 2022

Abstract Highly infectious viral diseases are a serious threat to mankind as they can spread rapidly among the community, possibly even leading loss of many lives. Early diagnosis disease not only increases chance quick recovery, but also helps prevent infections. There is thus an urgent need for accurate, ultrasensitive, rapid, and affordable diagnostic techniques test large volumes population track thereby control diseases, evidenced during COVID-19 other pandemics. This review paper critically comprehensively reviews various emerging nanophotonic biosensor mechanisms technologies virus detection, with particular focus on detection SARS-CoV-2 (COVID-19) virus. The photonic biosensing that we have focused include: (a) plasmonic field enhancement via localized surface plasmon resonances, (b) enhanced Raman scattering, (c) nano-Fourier transform infrared (nano-FTIR) near-field spectroscopy, (d) fiber Bragg gratings, (e) microresonators (whispering gallery modes), emphasis impact nanomaterials two-dimensional materials in these sensing technologies. discusses several quantitative issues related optical transduction techniques, notably factors affect limit (LoD), sensitivity, specificity, response times above detection. We analyze future prospects cost-effective, lab-on-a-chip solutions promise ultrahigh sensitivities, rapid speeds, mass manufacturability.

Language: Английский

Citations

17