Effect of emerging pollutants on the gut microbiota of freshwater animals: Focusing on microplastics and pesticides

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 948, P. 174809 - 174809

Published: July 15, 2024

Language: Английский

---

How to analyse and account for interactions in mixture toxicity with toxicokinetic-toxicodynamic models

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 843, P. 157048 - 157048

Published: June 30, 2022

Language: Английский

---

Pesticide exposure and human health: Toxic legacy

Clinics, Journal Year: 2023, Volume and Issue: 78, P. 100249 - 100249

Published: Jan. 1, 2023

Language: Английский

---

Interactive effects of dinotefuran and Nosema ceranae on the survival status and gut microbial community of honey bees

Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 200, P. 105808 - 105808

Published: Feb. 1, 2024

Language: Английский

---

Pesticides: Unintended Impact on the Hidden World of Gut Microbiota

Metabolites, Journal Year: 2024, Volume and Issue: 14(3), P. 155 - 155

Published: March 7, 2024

A vast range of pesticides have been routinely employed for plant protection throughout the last few decades. Pesticides can enter non-target organisms in various ways, posing health hazards. Exposure to different environmental pollutants, including pesticides, affect human gut flora. Metabolites generated from microbiota play an essential role host's by regulating metabolic homeostasis. disruption this equilibrium lead emergence numerous illnesses and their etiology. shown a recent studies harm microbiome. As result, there is urgent need investigate impact on microbiota-mediated immunity. Metabolic alterations host may give better understanding pesticide-induced harm. This review highlights potential consequences pesticide exposure composition function, mainly focusing how it might alter production secondary metabolites with downstream implications health.

Language: Английский

---

Role-Playing Between Environmental Pollutants and Human Gut Microbiota: A Complex Bidirectional Interaction

Frontiers in Medicine, Journal Year: 2022, Volume and Issue: 9

Published: Feb. 16, 2022

There is a growing interest in the characterization of involvement toxicant and pollutant exposures development progression several diseases such as obesity, diabetes, cancer, well disruption immune reproductive homeostasis. The gut microbiota considered pivotal player against toxic properties chemicals with establishment dynamic bidirectional relationship, underlining toxicological significance this mutual interplay. In fact, environmental have been demonstrated to affect composition, biodiversity intestinal together modulated metabolic pathways, which may play an important role tailoring microbiotype individual. review, we aimed discuss latest updates concerning chemicals-microbiota dual interaction, toward identification distinctiveness microbial community, which, turn, allow adopt personalized preventive strategies improve risk assessment for more susceptible workers.

Language: Английский

---

Artificial Intelligence-Aided Meta-Analysis of Toxicological Assessment of Agrochemicals in Bees

Frontiers in Ecology and Evolution, Journal Year: 2022, Volume and Issue: 10

Published: May 19, 2022

The lack of consensus regarding pollinator decline in various parts the planet has generated intense debates different spheres. Consequently, much research attempted to identify leading causes this decline, and a multifactorial synergism (i.e., stressors acting together mutually potentiating harmful effects) seems be emerging explaining phenomenon. emphasis on some stressor groups such as agrochemicals, pollinators honey bee Apis mellifera , can hide real risk anthropogenic pollinating insects. In present study, we conducted systematic review literature general temporal trends publications, considering their exposure agrochemicals over last 76 years. Through an artificial intelligence (AI)-aided meta-analysis, quantitatively assessed publications agrochemicals. Using AI tools through machine learning enabled efficient evaluation large volume published articles. Toxicological assessment impact insect is dominated by order Hymenoptera, which includes bees. Although bees are well-explored, there articles exploring toxicological for bumble bees, solitary stingless data gathered provide insights into current scenario imposed serve guide further area. Systematic Review Registration https://asreview.nl/ .

Language: Английский

---

Azoxystrobin Disrupts Colonic Barrier Function in Mice via Metabolic Disorders Mediated by Gut Microbiota

Journal of Agricultural and Food Chemistry, Journal Year: 2023, Volume and Issue: 71(1), P. 789 - 801

Published: Jan. 3, 2023

The widespread use of azoxystrobin (AZO) over the past few decades has drawn great attention to its environmental health effects. objective present study was explore effects AZO on intestinal barrier function in mice from perspective gut microbiota. Specifically, exposure could cause colonic dysfunction mice. Meanwhile, also dysbiosis Further studies revealed that metabolic profile microbiota significantly disturbed with exposure. Last but not least, we confirmed played a central role AZO-induced through transplantation experiment. Gut mediated induced by via inducing profile. findings this strongly support new insight can be key target risks pesticides.

Language: Английский

---

Gut microbiota disorders aggravate terbuthylazine-induced mitochondrial quality control disturbance and PANoptosis in chicken hepatocyte through gut-liver axis

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 913, P. 169642 - 169642

Published: Dec. 29, 2023

Language: Английский

---

The hidden threat: Environmental toxins and their effects on gut microbiota

Pathology - Research and Practice, Journal Year: 2024, Volume and Issue: 255, P. 155173 - 155173

Published: Jan. 28, 2024

Language: Английский

---