Genetic Engineering and Genome Editing Advances to Enhance Floral Attributes in Ornamental Plants: An Update DOI Creative Commons
Manjulatha Mekapogu,

Hyun-Young Song,

So-Hyeon Lim

et al.

Plants, Journal Year: 2023, Volume and Issue: 12(23), P. 3983 - 3983

Published: Nov. 27, 2023

The ornamental horticulture industry is a highly dynamic and rapidly changing market. Constant development of novel cultivars with elite traits essential to sustain competitiveness. Conventional breeding has been used develop cultivars, which often laborious. Biotechnological strategies such as genetic engineering have crucial in manipulating improving various beneficial that are technically not possible through cross-breeding. One trait the desired blue-colored flower roses chrysanthemums, can be achieved transgenic technology. Advances genome sequencing platforms enhanced opportunities access whole sequence ornamentals, facilitating dissection molecular genetics regulatory controls different traits. recent advent editing tools, including CRISPR/Cas9, revolutionized plant breeding. CRISPR/Cas9-based gene offers efficient precise modification, contributing advancements. Although ornamentals currently its infancy, increase availability sequences provides platform extend frontiers future ornamentals. Hence, this review depicts implication commercially valuable attributes, details research attempts achievements enhancing floral attributes using plants.

Language: Английский

Plant Foods and Their Bioactives as Dietary Enhancers for Colon Cancer Treatment with 5-Fluorouracil DOI
Zhongming Yang, Carlos L. Céspedes, Zhongguo Yang

et al.

Food Reviews International, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 50

Published: Jan. 4, 2025

Cancer is the world's second most common cause of death, with colon cancer (CC) ranking third in prevalence and cancer-related fatalities. CC originates or rectum influenced by genetic mutations, lifestyle, diet. Although chemotherapy, especially 5-fluorouracil (5-FU), fundamental to treatment has improved patient survival, its benefits are often limited significant side effects emerging drug resistance. Recently, plant-based foods have drawn interest research for their natural bioactive compounds relatively low toxicity. Certain plant not only exhibit anti-cancer activity but may also boost effectiveness 5-FU while reducing adverse effects. Despite evidence suggesting a synergistic effect between 5-FU, this area remains fragmented. This review consolidates current on including fruits, vegetables, legumes, tea bioactives treatment. Besides, it explores mechanisms through which these enhance efficacy reduce effects, evaluates clinical application prospects, identifies challenges future directions. comprehensive analysis aims provide scientific foundation integrated CC, highlighting potential enhancing chemotherapy associated toxicities.

Language: Английский

Citations

7

Antimicrobial Potential of Polyphenols: Mechanisms of Action and Microbial Responses—A Narrative Review DOI Creative Commons
Luca Rossi, Gabriele Rocchetti, Luigi Lucini

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(2), P. 200 - 200

Published: Feb. 10, 2025

Polyphenols (PPs) are recognized as bioactive compounds and antimicrobial agents, playing a critical role in enhancing food safety, preservation, extending shelf life. The effectiveness of PPs has different molecular biological reasons, predominantly linked to their hydroxyl groups electron delocalization, which interact with microbial cell membranes, proteins, organelles. These interactions may reduce the efficiency metabolic pathways, cause destructive damage membrane, or they harm proteins nucleic acids foodborne bacteria. Moreover, exhibit distinctive ability form complexes metal ions, further amplifying activity. This narrative review explores complex multifaceted between pathogens, underlying correlation chemical structures mechanisms action. Such insights shed light on potential innovative natural preservatives within systems, presenting an eco-friendly sustainable alternative synthetic additives.

Language: Английский

Citations

7

Green synthesis of ZnFe2O4@ZnO nanocomposites using Chrysanthemum spp. floral waste for photocatalytic dye degradation DOI

Ngoan Thi Thao Nguyen,

Luan Minh Nguyen, Thuy Thi Thanh Nguyen

et al.

Journal of Environmental Management, Journal Year: 2022, Volume and Issue: 326, P. 116746 - 116746

Published: Nov. 16, 2022

Language: Английский

Citations

50

Cloned genes and genetic regulation of anthocyanin biosynthesis in maize, a comparative review DOI Creative Commons
Zaid Chachar,

Ruiqiang Lai,

Nazir Ahmed

et al.

Frontiers in Plant Science, Journal Year: 2024, Volume and Issue: 15

Published: Jan. 24, 2024

Anthocyanins are plant-based pigments that primarily present in berries, grapes, purple yam, corn and black rice. The research on fruit with a high anthocyanin content is not sufficiently extensive. Considering its crucial role nutrition health it vital to conduct further studies how accumulates explore potential for edible medicinal purposes. Anthocyanin biosynthesis plays an important maize stems (corn). Several beneficial compounds, particularly cyanidin-3-O-glucoside, perlagonidin-3-O-glucoside, peonidin 3-O-glucoside, their malonylated derivatives have been identified. C1, C2, Pl1, Pl2, Sh2, ZmCOP1 ZmHY5 harbored functional alleles played the of anthocyanins maize. Sh2 gene regulates sugar-to-starch conversion, thereby influencing kernel quality nutritional content. key regulatory genes control light responses photomorphogenesis. This review concludes molecular identification all encoding structural enzymes pathway by describing cloning characterization these genes. Our study presents new understandings processes behind manufacture maize, which will contribute development genetically modified variants crop increased color possible advantages.

Language: Английский

Citations

9

Characterization of key genes in anthocyanin and flavonoid biosynthesis during floral development in Rosa canina L. DOI

Parisa Jariani,

Ali-Akbar Shahnejat-Bushehri,

Roohangiz Naderi

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 276, P. 133937 - 133937

Published: July 17, 2024

Language: Английский

Citations

9

CmBBX28‐CmMYB9a Module Regulates Petal Anthocyanin Accumulation in Response to Light in Chrysanthemum DOI Open Access
Lijie Zhou,

Jialin Peng,

Chuwen Chen

et al.

Plant Cell & Environment, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 16, 2025

ABSTRACT Light is one of the most important environmental factors that affect plant growth and development. It also stimulates anthocyanin biosynthesis in plants. However, precise molecular mechanisms through which light regulates biosynthesis, particularly non‐model species, remain poorly understood. In this study, we discovered a CmBBX28‐CmMYB9a module responsive to chrysanthemums. Specifically, CmBBX28 interacts with CmMYB9a, interfering its binding promoters target genes reducing protein abundance CmMYB9a. This interaction downregulates transcription CmMYB9a's downstream anthocyanin‐associated genes, CmCHS , CmDFR CmUFGT . The expression was induced dark, accumulated proteins interfered activation CmMYB9a during biosynthesis. Concurrently, darkness inhibited some extent. contrast, significantly suppressed resulting increased accumulation chrysanthemum petals. Our findings reveal mechanism by flower

Language: Английский

Citations

1

Regulation of MYB Transcription Factors of Anthocyanin Synthesis in Lily Flowers DOI Creative Commons

Xiaojuan Yin,

Yi-Bing Zhang, Li Zhang

et al.

Frontiers in Plant Science, Journal Year: 2021, Volume and Issue: 12

Published: Dec. 1, 2021

Flower color is the decisive factor that affects commercial value of ornamental flowers. Therefore, it important to study regulation flower formation in lily discover positive and negative factors regulate this trait. In study, MYB transcription (TFs) were characterized understand regulatory mechanism anthocyanin biosynthesis lily. Two R2R3-MYB TFs, LvMYB5, LvMYB1, found which has an activation motif, belongs SG6 protein subgroup Arabidopsis thaliana. Transient expression LvMYB5 indicated can promote coloration Nicotiana benthamiana leaves, increases levels NbCHS, NbDFR, NbANS. VIGS experiments petals showed accumulation anthocyanins was reduced when silenced. Luciferase assays synthesis by activating ANS gene promoter. plays role addition, transient experiment provided preliminary evidence LvMYB1 (an TF) inhibits The discovery inhibitory related provides a theoretical basis for improving through genetic engineering. results our provide new direction further mechanisms lilies.

Language: Английский

Citations

55

The genus Chrysanthemum: Phylogeny, biodiversity, phytometabolites, and chemodiversity DOI Creative Commons
Da‐Cheng Hao,

Yanjun Song,

Peigen Xiao

et al.

Frontiers in Plant Science, Journal Year: 2022, Volume and Issue: 13

Published: Aug. 11, 2022

The ecologically and economically important genus Chrysanthemum contains around 40 species many hybrids cultivars. dried capitulum of morifolium (CM) Ramat. Tzvel, i.e., Flos Chrysanthemi , is frequently used in traditional Chinese medicine (TCM) folk for at least 2,200 years. It has also been a popular tea beverage about 2,000 years since Han Dynasty China. However, the origin different cultivars CM phylogenetic relationship between related Asteraceae genera are still elusive, there lack comprehensive review association biodiversity chemodiversity . This article aims to provide synthetic summary phylogeny, biodiversity, phytometabolites taxonomic groups, focusing on its wild relatives. Based extensive literature light medicinal value chrysanthemum, we give some suggestions with genera/species future applications. Mining from containing subtribe Artemisiinae, as well mining therapeutic efficacy other utilities chemodiversity/biodiversity, closely sustainable conservation utilization Artemisiinae resources. There were eight main Hangju, Boju, Gongju, Chuju, Huaiju, Jiju, Chuanju Qiju, which differ geographical origins processing methods. Different originated various hybridizations multiple species. They mainly contained volatile oils, triterpenes, flavonoids, phenolic acids, polysaccharides, amino acids phytometabolites, have activities antimicrobial, anti-viral, antioxidant, anti-aging, anticancer, anti-inflammatory, groups could be useful food, tea. Despite progresses, genetic/chemical relationships among varieties, relevant yet clarified; therefore, roles pharmacophylogeny omics technology highlighted.

Language: Английский

Citations

38

Towards the Improvement of Ornamental Attributes in Chrysanthemum: Recent Progress in Biotechnological Advances DOI Open Access
Manjulatha Mekapogu,

Oh-Keun Kwon,

Hyun-Young Song

et al.

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(20), P. 12284 - 12284

Published: Oct. 14, 2022

Incessant development and introduction of novel cultivars with improved floral attributes are vital in the dynamic ornamental industry. Chrysanthemum (Chrysanthemum morifolium) is a highly favored plant, ranking second globally cut flower trade, after rose. Development new chrysanthemum innovative modifications attributes, including color, shape, plant architecture, flowering time, enhanced shelf life, biotic abiotic stress tolerance, major goal breeding. Despite being an economically important application conventional molecular breeding approaches to various key traits hindered owing its genomic complexity, heterozygosity, limited gene pool availability. Although classical has resulted several hundreds morphological variations, genetic transcriptional control remains unclear. The coveted blue colored flowers chrysanthemums cannot be achieved through mutation due technical limitations. However, blue-hued been developed by engineering, transgenic successfully employed, leading substantial progress improving traits. recent availability whole-genome sequences offers platform extensively employ MAS identify large number markers for QTL mapping, GWAS dissect complex combination NGS, multi-omic platforms, genome editing technologies provided tremendous scope decipher regulatory mechanisms. integration these remain inadequate chrysanthemum. This review, therefore, details significance describes efforts advancements, highlights possibilities future towards improvement crucial popular plant.

Language: Английский

Citations

33

Phytochemicals, therapeutic benefits and applications of chrysanthemum flower: A review DOI Creative Commons
Niharika Sharma,

Radha CHAUHAN,

Manoj Kumar

et al.

Heliyon, Journal Year: 2023, Volume and Issue: 9(10), P. e20232 - e20232

Published: Sept. 15, 2023

Chrysanthemum is a flowering plant belonging to genus of the dicotyledonous herbaceous annual Asteraceae (Compositae) family. It perpetual plant, mostly cultivated for medicinal purposes; generally, used in popular drinks due its aroma and flavor. primarily China, Japan, Europe, United States. These flowers were extensively various healthcare systems treating diseases. are rich phenolic compounds exhibit strong properties including antioxidant, antimicrobial, anti-inflammatory, anticancer, anti-allergic, anti-obesity, immune regulation, hepatoprotective, nephroprotective activities. The main aim present review was investigate nutritional profile, phytochemistry, biological activities different species. Also, critical discussion diverse metabolites or bioactive constituents highlighted review. Moreover, flower extracts have been assessed possess phytochemical such as cyanidin-3-O-(6″-O-malonyl) glucoside, delphinidin 3-O-(6" -O-malonyl) glucoside-3′, rutin, quercetin, isorhamnetin, rutinoside, others. profiles potential health benefits, leading their utilization production supplementary food products pharmaceutical drugs within industry. However, more comprehensive research studies/investigations still needed further discover benefits human animal utilization.

Language: Английский

Citations

20