Engineered Regeneration,
Journal Year:
2024,
Volume and Issue:
5(3), P. 326 - 341
Published: July 2, 2024
Silver
nanoparticles
are
among
the
most
widely
researched
and
used
for
nanotechnology-derived
structures
due
to
their
extraordinary
inherent
optical
properties,
chemical
stability,
catalytic
activity,
high
conductivity.
These
idiosyncratic
properties
can
be
attributed
unique
physico-chemical
characteristics,
such
as
ultrafine
sizes,
surface
area,
diverse
shapes,
strong
localized
plasmon
resonance.
distinctive
features
tailored
using
various
physical,
chemical,
biological
synthesis
methods.
Various
physical
techniques
viable
producing
silver
on
a
large
scale,
but
they
suffer
from
drawbacks
high-power
consumption,
expensive
set-up,
limited
control
over
nanoparticle
size
distribution.
Chemical
methods
provide
benefits
like
yield,
consistent
shape
distribution,
cost
efficiency,
residual
toxicity
of
chemicals
involved
hinders
applications.
Biological
approaches
effectively
overcome
limitations
both
by
eliminating
need
hazardous
chemicals,
requiring
less
energy,
enabling
morphologies,
offering
eco-friendliness
exceptional
biocompatibility.
The
novel
promising
nanosilver-based
biomaterials
have
been
demonstrated
suitable
wide
range
pharmacological
therapeutic
biomedical
Their
extensive
application
in
wound
healing,
dentistry,
cardiovascular
disease
treatment,
nerve
tissue
engineering,
cancer
biosensing
antimicrobial
antibiofilm
antithrombotic
potential
regeneration,
photothermal
conversion
efficiency
sensitivity,
respectively.
This
review
discusses
different
employed
synthesising
focuses
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(9), P. 1886 - 1886
Published: Sept. 6, 2022
Solid
lipid
nanoparticles
(SLNs)
are
an
alternate
carrier
system
to
liposomes,
polymeric
nanoparticles,
and
inorganic
carriers.
SLNs
have
attracted
increasing
attention
in
recent
years
for
delivering
drugs,
nucleic
acids,
proteins,
peptides,
nutraceuticals,
cosmetics.
These
nanocarriers
industrial
due
their
ease
of
preparation,
physicochemical
stability,
scalability.
characteristics
make
attractive
manufacture
on
a
large
scale.
Currently,
several
products
with
clinical
trials,
there
is
high
possibility
that
SLN
carriers
will
quickly
increase
presence
the
market.
A
large-scale
manufacturing
unit
required
commercial
applications
prepare
enough
formulations
studies.
Furthermore,
continuous
processing
becoming
more
popular
pharmaceutical
sector
reduce
product
batch-to-batch
differences.
This
review
paper
discusses
some
conventional
methods
rationale
production.
It
further
covers
progress
scale-up
synthesis
SLNs,
including
high-pressure
homogenization
(HPH),
hot
melt
extrusion
coupled
HPH,
microchannels,
nanoprecipitation
using
static
mixers,
microemulsion-based
methods.
technologies
enable
commercialization
SLNs.
ongoing
studies
indicate
these
eventually
reach
Molecules,
Journal Year:
2023,
Volume and Issue:
28(1), P. 463 - 463
Published: Jan. 3, 2023
The
unique
biological
and
physicochemical
characteristics
of
biogenic
(green-synthesized)
nanomaterials
(NMs)
have
attracted
significant
interest
in
different
fields,
with
applications
the
agrochemical,
food,
medication
delivery,
cosmetics,
cellular
imaging,
biomedical
industries.
To
synthesize
nanomaterials,
green
synthesis
techniques
use
microorganisms,
plant
extracts,
or
proteins
as
bio-capping
bio-reducing
agents
their
role
bio-nanofactories
for
material
at
nanoscale
size.
Green
chemistry
is
environmentally
benign,
biocompatible,
nontoxic,
economically
effective.
By
taking
into
account
findings
from
recent
investigations,
we
shed
light
on
most
developments
using
types
microbes
plants.
Additionally,
cover
green-synthesized
food
textile
industries,
water
treatment,
applications.
Furthermore,
discuss
future
perspectives
to
advance
production
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2023,
Volume and Issue:
11
Published: May 2, 2023
Graphical
Abstract
Sources
for
biogenic
synthesis:
The
synthesis
sources
include
but
are
not
limited
to
bacteria,
fungi,
algae,
yeasts,
marine
and
plant
sources.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(9), P. 1860 - 1860
Published: Sept. 3, 2022
With
the
growing
burden
of
cancer,
parallel
advancements
in
anticancer
nanotechnological
solutions
have
been
witnessed.
Among
different
types
cancers,
breast
cancer
accounts
for
approximately
25%
and
leads
to
15%
deaths.
Nanomedicine
its
allied
fields
material
science
revolutionized
medicine
21st
century.
Novel
treatments
paved
way
improved
drug
delivery
systems
that
better
efficacy
reduced
adverse
effects.
A
variety
nanoformulations
using
lipids,
polymers,
inorganic,
peptide-based
nanomedicines
with
various
functionalities
are
being
synthesized.
Thus,
elaborate
knowledge
these
intelligent
highly
promising
is
prime
importance.
Polymeric
micelles
(PMs)
generally
easy
prepare
good
solubilization
properties;
hence,
they
appear
be
an
attractive
alternative
over
other
nanosystems.
Although
overall
perspective
PM
has
presented
recent
reviews,
a
brief
discussion
provided
on
PMs
cancer.
This
review
provides
state-of-the-art
together
most
advances
this
field.
Furthermore,
special
emphasis
placed
regulatory
guidelines,
clinical
translation
potential,
future
aspects
use
treatment.
The
developments
micelle
formulations
look
promising,
guidelines
now
more
clearly
defined;
we
anticipate
early
near
future.
Journal of Nanobiotechnology,
Journal Year:
2023,
Volume and Issue:
21(1)
Published: Aug. 26, 2023
Bacterial
infections,
especially
those
caused
by
drug-resistant
bacteria,
have
seriously
threatened
human
life
and
health.
There
is
urgent
to
develop
new
antibacterial
agents
reduce
the
problem
of
antibiotics.
Biomedical
materials
with
good
antimicrobial
properties
been
widely
used
in
applications.
Among
them,
hydrogels
become
focus
research
field
biomedical
due
their
unique
three-dimensional
network
structure,
high
hydrophilicity,
biocompatibility.
In
this
review,
latest
progresses
about
recent
years
were
summarized,
mainly
including
preparation
methods
According
different
mechanisms,
several
representative
introduced,
such
as
antibiotics
loaded
hydrogels,
antibiotic-free
metal-based
peptide
polymers,
stimuli-responsive
smart
light-mediated
hydrogels.
addition,
we
also
discussed
applications
challenges
biomedicine,
which
are
expected
provide
directions
ideas
for
application
clinical
therapy.
Applied Biochemistry and Biotechnology,
Journal Year:
2023,
Volume and Issue:
196(6), P. 3636 - 3669
Published: Sept. 5, 2023
Silver
nanoparticles
(AgNPs)
possess
unmatched
chemical,
biological,
and
physical
properties
that
make
them
unique
compounds
as
antimicrobial,
antifungal,
antiviral,
anticancer
agents.
With
the
increasing
drug
resistance,
AgNPs
serve
promising
entities
for
targeted
therapy
against
several
bacterial,
fungal,
viral
components.
In
addition,
also
successful
agents
cancers,
including
breast,
prostate,
lung
cancers.
Several
works
in
recent
years
have
been
done
towards
development
of
by
using
plant
extracts
like
flowers,
leaves,
bark,
root,
stem,
whole
parts.
The
green
method
AgNP
synthesis
thus
has
advantages
over
chemical
methods,
especially
low
cost
synthesis,
no
toxic
byproducts,
eco-friendly
production
pathways,
can
be
easily
regenerated,
bio-reducing
potential
derived
nanoparticles.
Furthermore,
are
biocompatible
do
not
harm
normally
functioning
human
or
host
cells.
This
review
provides
an
exhaustive
overview
synthesized
used
After
a
brief
introduction,
we
discussed
studies
on
from
different
extracts,
leaf
parts,
seeds,
stems,
plants.
following
section,
highlighted
therapeutic
actions
various
bacteria,
fungi,
viruses,
We
then
general
mechanism
action
AgNPs.
methods
were
article.
Finally,
concluded
providing
future
perspectives
this
field
nanotechnology.
Sensors,
Journal Year:
2023,
Volume and Issue:
23(7), P. 3692 - 3692
Published: April 2, 2023
With
rapidly
increasing
environmental
pollution,
there
is
an
urgent
need
for
the
development
of
fast,
low-cost,
and
effective
sensing
devices
detection
various
organic
inorganic
substances.
Silver
nanoparticles
(AgNPs)
are
well
known
their
superior
optoelectronic
physicochemical
properties,
have,
therefore,
attracted
a
great
deal
interest
in
sensor
arena.
The
introduction
AgNPs
onto
surface
two-dimensional
(2D)
structures,
incorporation
into
conductive
polymers,
or
within
three-dimensional
(3D)
nanohybrid
architectures
common
strategy
to
fabricate
novel
platforms
with
improved
chemical
physical
properties
analyte
sensing.
In
first
section
this
review,
main
wet
reduction
approaches
successful
synthesis
functional
electrochemical
applications
discussed.
Then,
brief
on
principles
voltammetric
amperometric
sensors
given.
current
utilization
silver
silver-based
composite
nanomaterials
fabrication
as
pollutants
water
matrices
summarized.
Finally,
challenges
future
directions
nanosilver-based
outlined.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(8), P. 3403 - 3403
Published: April 12, 2023
Iron
oxide
nanoparticles
(NPs)
have
attracted
substantial
interest
due
to
their
superparamagnetic
features,
biocompatibility,
and
nontoxicity.
The
latest
progress
in
the
biological
production
of
Fe3O4
NPs
by
green
methods
has
improved
quality
applications
significantly.
In
this
study,
fabrication
iron
from
Spirogyra
hyalina
Ajuga
bracteosa
was
conducted
via
an
easy,
environmentally
friendly,
cost-effective
process.
fabricated
were
characterized
using
various
analytical
study
unique
properties.
UV-Vis
absorption
peaks
observed
algal
plant-based
at
289
nm
306
nm,
respectively.
Fourier
transform
infrared
(FTIR)
spectroscopy
analyzed
diverse
bioactive
phytochemicals
present
plant
extracts
that
functioned
as
stabilizing
capping
agents
NPs.
X-ray
diffraction
revealed
crystalline
nature
both
biofabricated
small
size.
Scanning
electron
microscopy
(SEM)
algae
are
spherical
rod-shaped,
averaging
52
75
Energy
dispersive
showed
green-synthesized
require
a
high
mass
percentage
oxygen
ensure
synthesis.
exhibited
stronger
antioxidant
properties
than
algal-based
efficient
antibacterial
potential
against
E.
coli,
while
displayed
higher
zone
inhibition
S.
aureus.
Moreover,
superior
scavenging
compared
This
might
be
greater
number
plants
surround
during
fabrication.
Hence,
over
improves
applications.
Biomedical Microdevices,
Journal Year:
2024,
Volume and Issue:
26(1)
Published: Jan. 23, 2024
Abstract
The
rise
in
drug
resistance
pathogenic
bacteria
greatly
endangers
public
health
the
post-antibiotic
era,
and
drug-resistant
currently
pose
a
great
challenge
not
only
to
community
but
also
clinical
procedures,
including
surgery,
stent
implantation,
organ
transplantation,
other
medical
procedures
involving
any
open
wound
compromised
human
immunity.
Biofilm-associated
failure,
as
well
rapid
last-resort
antibiotics,
necessitates
search
for
novel
treatments
against
bacterial
infection.
In
recent
years,
flourishing
development
of
nanotechnology
has
provided
new
insights
exploiting
promising
alternative
therapeutics
bacteria.
Metallic
agents
have
been
applied
antibacterial
usage
several
centuries,
functional
modification
metal-based
biomaterials
using
now
attracted
interest
field,
their
intrinsic
nature
ready
on-demand
functionalization
enhanced
interaction
with
bacteria,
rendering
them
good
potential
further
translation.
However,
possible
toxicity
MNPs
host
cells
tissue
still
hinders
its
application,
current
knowledge
on
cellular
pathways
is
enough.
This
review
will
focus
advances
developing
metallic
nanoparticles
(MNPs),
silver,
gold,
copper,
nanoparticles,
applications,
mechanisms
hosts.