Recent Advances in the Additive Manufacturing of Stimuli‐Responsive Soft Polymers

Advanced Engineering Materials, Journal Year: 2023, Volume and Issue: 25(21)

Published: Aug. 29, 2023

Stimuli‐responsive polymers (SRPs) are special types of soft materials, which have been extensively used for developing flexible actuators, robots, wearable devices, sensors, self‐expanding structures, and biomedical thanks to their ability change shapes functional properties in response external stimuli including light, humidity, heat, pH, electric field, solvent, magnetic field or combinations two more these stimuli. In recent years, additive manufacturing (AM) aka 3D printing technology SRPs, also known as 4D printing, has gained phenomenal attention different engineering fields, its unique develop complex, personalized, innovative undergo twisting, elongating, swelling, rolling, shrinking, bending, spiraling, other complex morphological transformations. Herein, an effort made provide insightful information about the AM techniques, type applications including, but not limited tissue engineering, bionics, construction, smart textiles. This article incorporates current challenges prospects, hoping basis utilization this fields. It is expected that amalgamation with SRPs would unparalleled advantages arenas.

Language: Английский

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3D printing of stimuli-responsive hydrogel materials: Literature review and emerging applications

Giant, Journal Year: 2023, Volume and Issue: 17, P. 100209 - 100209

Published: Nov. 15, 2023

Additive manufacturing (AM) aka three-dimensional (3D) printing has been a well-established and unparalleled technology, which is expanding the boundaries of materials science exhibiting an enormous potential to fabricate intricate geometries for healthcare, electronics, construction sectors. In contemporary era, combination AM technology stimuli-responsive hydrogels (SRHs) helps create dynamic functional structures with extreme accuracy, are capable changing their shape, functional, or mechanical properties in response environmental cues such as humidity, heat, light, pH, magnetic field, electric etc. 3D SRHs permits creation on-demand dynamically controllable shapes excellent control over various self-repair, self-assembly, multi-functionality, These accelerate researchers think unthinkable applications. Additively manufactured objects have shown applications like tissue engineering, drug delivery, soft robots, sensors, other biomedical devices. The current review provides recent progress SRHs, more focus on techniques, stimuli mechanisms, shape morphing behaviors, Finally, trends future roadmap additively smart different also presented, will be helpful research. This holds great promise providing fundamental knowledge about diverse

Language: Английский

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4D printing roadmap

Smart Materials and Structures, Journal Year: 2024, Volume and Issue: 33(11), P. 113501 - 113501

Published: June 26, 2024

Abstract Four-dimensional (4D) printing is an advanced manufacturing technology that has rapidly emerged as a transformative tool with the capacity to reshape various research domains and industries. Distinguished by its integration of time dimension, 4D allows objects dynamically respond external stimuli, setting it apart from conventional 3D printing. This roadmap been devised, contributions 44 active researchers in this field 32 affiliations world-wide, navigate swiftly evolving landscape printing, consolidating recent advancements making them accessible experts across diverse fields, ranging biomedicine aerospace, textiles electronics. The roadmap’s goal empower both enthusiasts, facilitating exploitation printing’s potential create intelligent, adaptive are not only feasible but readily attainable. By addressing current future challenges proposing science technology, sets stage for revolutionary progress numerous industries, positioning future.

Language: Английский

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Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(6), P. 531 - 531

Published: March 16, 2024

Biomimetic scaffolds imitate native tissue and can take a multidimensional form. They are biocompatible influence cellular metabolism, making them attractive bioengineering platforms. The use of biomimetic adds complexity to traditional cell cultivation methods. most commonly used technique involves cultivating cells on flat surface in two-dimensional format due its simplicity. A three-dimensional (3D) provide microenvironment for surrounding cells. There two main techniques obtaining 3D structures based the presence scaffolding. Scaffold-free consist spheroid technologies. Meanwhile, scaffold contain organoids all constructs that various types scaffolds, ranging from decellularized extracellular matrix (dECM) through hydrogels one extensively studied forms potential culture up 4D bioprinted biomaterials. bioprinting is important create scaffolds. versatility this allows many different inks, mainly hydrogels, as well inorganic substances. Increasing amounts data evidence vast usage engineering personalized medicine, with area application being regeneration skin musculoskeletal systems. Recent papers also indicate increasing vivo tests products which further strengthen importance branch emphasize need extensive research safe humansbiomimetic tissues organs. In review article, we recent advancements field preceded by an overview technologies led development complex type culture.

Language: Английский

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Additive Manufacturing for Surgical Planning and Education: A Review

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(6), P. 2550 - 2550

Published: March 18, 2024

Additive manufacturing has been widely used in various industries, including the healthcare sector. Over last few decades, AM playing an important role medical field different areas, surgical planning, implants, and educational activities. For applications, can help surgeons practice plan operation until they are confident with process. This to reduce operational risk time. In addition, it demonstrate problem other colleagues. also produce 3D models teach students doctors about human anatomy. paper aims comprehensively review diverse applications of additive within domains planning education. By focusing on multifaceted roles played by these critical a contribution growing body knowledge that underscores transformative potential this technology shaping future practices is sought be made.

Language: Английский

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A review on additive manufacturing of lattice structures in tissue engineering

Bioprinting, Journal Year: 2023, Volume and Issue: 35, P. e00304 - e00304

Published: Aug. 12, 2023

Language: Английский

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4D Printing: The Development of Responsive Materials Using 3D-Printing Technology

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(12), P. 2743 - 2743

Published: Dec. 7, 2023

Additive manufacturing, widely known as 3D printing, has revolutionized the production of biomaterials. While conventional 3D-printed structures are perceived static, 4D printing introduces ability to fabricate materials capable self-transforming their configuration or function over time in response external stimuli such temperature, light, electric field. This transformative technology garnered significant attention field biomedical engineering due its potential address limitations associated with traditional therapies. Here, we delve into an in-depth review 4D-printing systems, exploring diverse applications and meticulously evaluating advantages disadvantages. We emphasize novelty this paper by highlighting latest advancements emerging trends technology, particularly context applications.

Language: Английский

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A comprehensive exploration of shape memory alloys: Fundamentals, structural reinforcements, nano-analysis, machine learning perspective, and emerging applications

Mechanics of Advanced Materials and Structures, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 34

Published: Jan. 30, 2024

Shape memory alloys (SMAs) are widely used across various industries, including medicine, due to their inherent properties such as the shape effect, pseudo-elasticity, antigenicity, decomposition, biodegradability, biocompatibility, resistance corrosion, and wear. This review article aims cover different aspects of SMAs, fundamental concepts origin, exceptional properties, fabrication techniques, structural analysis. Exploring SMAs at nanoscale using molecular dynamics analysis recent studies that integrate machine learning techniques. Finally, concludes with a discussion applications considering potential fields use.

Language: Английский

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Bioprinting of Cells, Organoids and Organs-on-a-Chip Together with Hydrogels Improves Structural and Mechanical Cues

Cells, Journal Year: 2024, Volume and Issue: 13(19), P. 1638 - 1638

Published: Oct. 1, 2024

The 3D bioprinting technique has made enormous progress in tissue engineering, regenerative medicine and research into diseases such as cancer. Apart from individual cells, a collection of organoids, can be printed combination with various hydrogels. It hypothesized that will even become promising tool for mechanobiological analyses organoids their matrix environments highly defined precisely structured environments, which the mechanical properties cell environment individually adjusted. Mechanical obstacles or bead markers integrated bioprinted samples to analyze deformations forces within these constructs, perform biophysical analysis complex systems, are still not standard techniques. review highlights advances 4D printing technologies integrating cues so next step detailed key future directions organoid generation development disease model regeneration drug testing perspective. Finally, hydrogels, pure natural synthetic hydrogels mixtures, organoid–cell co-cultures, organ-on-a-chip systems organoid-organ-on-a chip combinations introduces use assembloids determine mutual interactions different types cell–matrix interferences specific biological environments.

Language: Английский

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4D fabrication of shape-changing systems for tissue engineering: state of the art and perspectives

Progress in Additive Manufacturing, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 12, 2024

Abstract In recent years, four-dimensional (4D) fabrication has emerged as a powerful technology capable of revolutionizing the field tissue engineering. This represents shift in perspective from traditional engineering approaches, which generally rely on static—or passive—structures (e.g., scaffolds, constructs) unable adapting to changes biological environments. contrast, 4D offers unprecedented possibility fabricating complex designs with spatiotemporal control over structure and function response environment stimuli, thus mimicking processes. this review, an overview state art for obtainment cellularized constructs is presented, focus shape-changing soft materials. First, approaches obtain are introduced, also describing conventional non-conventional techniques their relative advantages limitations. Next, main families materials, namely shape-memory polymers hydrogels discussed use described. Ultimately, current challenges proposed solutions outlined, valuable insights into future research directions provided disclose its full potential.

Language: Английский

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