Historical insights of polyphenols in human health DOI
Javier Quero, Vı́ctor López, Francisco Les

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 3 - 42

Published: Jan. 1, 2025

Language: Английский

Understanding mechanisms of antioxidant action in health and disease DOI
Barry Halliwell

Nature Reviews Molecular Cell Biology, Journal Year: 2023, Volume and Issue: 25(1), P. 13 - 33

Published: Sept. 15, 2023

Language: Английский

Citations

237

Plant Polyphenols and Their Potential Benefits on Cardiovascular Health: A Review DOI Creative Commons
Iram Iqbal, Polrat Wilairatana, Fatima Saqib

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(17), P. 6403 - 6403

Published: Sept. 1, 2023

Fruits, vegetables, and other food items contain phytochemicals or secondary metabolites which may be considered non-essential nutrients but have medicinal importance. These dietary exhibit chemopreventive therapeutic effects against numerous diseases. Polyphenols are found in fruits, grains. compounds several health benefits such as immune modulators, vasodilators, antioxidants. This review focuses on recent studies using polyphenols to treat cardiovascular disorders, atherosclerosis, vascular endothelium deficits. We focus exploring the safety of highly effective ensure their maximum impact cardiac abnormalities discuss epidemiological evidence intervention trials related these properties. Kaempferol, quercetin, resveratrol prevent oxidative stress by regulating proteins that induce oxidation heart tissues. In addition, modulate tone vessels releasing nitric oxide (NO) reducing low-density lipoprotein (LDL) atherosclerosis. cardiomyocytes, suppress expression inflammatory markers inhibit production inflammation exert an anti-inflammatory response. Consequently, diseases strokes, hypertension, failure, ischemic disease could prevented polyphenols.

Language: Английский

Citations

80

Promising Application of Grape Pomace and Its Agri-Food Valorization: Source of Bioactive Molecules with Beneficial Effects DOI Open Access
Giusy Rita Caponio, Fabio Minervini, Grazia Tamma

et al.

Sustainability, Journal Year: 2023, Volume and Issue: 15(11), P. 9075 - 9075

Published: June 4, 2023

Grapes, particularly the species Vitis vinifera L., are one of most widely grown crops in world. Winemaking processes generate a high amount residues, which currently pose an environmental and economic sustainability problem for companies sector. For this reason, solutions being explored development new products with high-added value derived from valorization these residues. One wastes produced by winemaking is grape pomace, chemical composition promising because it rich compounds antioxidant activity, such as polyphenols (anthocyanins, flavonols, flavan-3-ols, procyanidins), phenolic acids, resveratrol, fiber. Commonly pomace used to produce distillates extract tartaric acid coloring substances enocyanin. Recently, alternative uses have been adopted, production extracts properties, fermentation substrates, composting biomass energy production, fiber extraction high-value-added enriched bioactive molecules pomace. Here, we discuss how involved various human biological functions their applications agri-food

Language: Английский

Citations

52

Marine algae: A treasure trove of bioactive anti-inflammatory compounds DOI

Dina S. Ghallab,

Reham S. Ibrahim, Mohamed M. Mohyeldin

et al.

Marine Pollution Bulletin, Journal Year: 2024, Volume and Issue: 199, P. 116023 - 116023

Published: Jan. 10, 2024

Language: Английский

Citations

25

Molecular crosstalk between polyphenols and gut microbiota in cancer prevention DOI
Falak Zeb, Huma Naqeeb, Tareq M. Osaili

et al.

Nutrition Research, Journal Year: 2024, Volume and Issue: 124, P. 21 - 42

Published: Jan. 27, 2024

Language: Английский

Citations

17

Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health DOI
Alice Njolke Mafe, Great Iruoghene Edo, Patrick Othuke Akpoghelie

et al.

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Language: Английский

Citations

8

Innovative strategies for valorization of byproducts from soybean industry: A review on status, challenges, and sustainable approaches towards zero-waste processing systems DOI Creative Commons
Ahasanul Karim,

Emmanuel Freddy Osse,

Seddik Khalloufi

et al.

Heliyon, Journal Year: 2025, Volume and Issue: unknown, P. e42118 - e42118

Published: Jan. 1, 2025

Language: Английский

Citations

3

Fermentation's pivotal role in shaping the future of plant-based foods: An integrative review of fermentation processes and their impact on sensory and health benefits DOI Creative Commons

Nazanin Abbaspour

Applied Food Research, Journal Year: 2024, Volume and Issue: 4(2), P. 100468 - 100468

Published: Aug. 9, 2024

Given the environmental, ethical, and food security challenges posed by conventional agriculture animal husbandry, transition towards sustainable systems is essential. Plant-based foods, especially those enhanced fermentation, present a viable solution. Fermentation reduces ecological footprint, aligns with ethical standards, enhances plant-based proteins' nutritional value sensory attributes, offering credible alternative to products. This paper explores fermentation's transformative role in developing meats, dairy, protein alternatives, emphasizing its benefits, including improved gut health through probiotics prebiotics. It also addresses such as producing undesirable by-products, potential risks, increased costs associated fermentation. Detailed examinations of specific fermentation processes—alcoholic, lactic acid, acetic propionic butyric acid—and their impact on enhancing value, digestibility, flavor foods are presented. Case studies from pioneering companies demonstrate technologies' practical applications market potential. Lastly, discusses future opportunities scaling up processes incorporating advanced biotechnological techniques further enhance sustainability outcomes.

Language: Английский

Citations

15

Taming neuroinflammation in Alzheimer's disease: The protective role of phytochemicals through the gut−brain axis DOI Open Access

Yoonsu Kim,

Jinkyu Lim, Jisun Oh

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2024, Volume and Issue: 178, P. 117277 - 117277

Published: Aug. 9, 2024

Language: Английский

Citations

14

Dietary (Poly)phenols and the Gut–Brain Axis in Ageing DOI Open Access
Léonie Láng, Simon McArthur, Alpár S. Lázár

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(10), P. 1500 - 1500

Published: May 16, 2024

As the population ages, incidence of age-related neurodegenerative diseases is rapidly increasing, and novel approaches to mitigate this soaring prevalence are sorely needed. Recent studies have highlighted importance gut microbial homeostasis its impact on brain functions, commonly referred as gut–brain axis, in maintaining overall health wellbeing. Nonetheless, mechanisms by which system acts remains poorly defined. In review, we will explore how (poly)phenols, a class natural compounds found many plant-based foods beverages, can modulate thereby promote neural health. While evidence indicates beneficial role (poly)phenol consumption part balanced diet, human scarce mechanistic insight still lacking. regard, make case that dietary (poly)phenols should be further explored establish their therapeutic efficacy through modulation with much greater emphasis carefully designed interventions.

Language: Английский

Citations

12