Plants, Journal Year: 2024, Volume and Issue: 13(18), P. 2640 - 2640
Published: Sept. 21, 2024
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Natural Product Communications, Journal Year: 2024, Volume and Issue: 19(5)
Published: May 1, 2024
The citrus plant is the general term for Citrus, Fortunella, and Poncirus, which includes oranges, tangerines, lemons, grapefruits, citrons. Not only does it contain a variety of delicious fruits, but also an important part traditional Chinese medicine. Citrus peels are rich in essential oils, primary active component limonene. Modern pharmacological research has revealed that limonene many effects, including antibacterial, anticancer, analgesic, immune regulation, neuroprotection, antioxidant, anti-inflammatory properties, treatment metabolic diseases. It finds widespread application industries, cosmetics, food, personal care, medicine, pesticides, others. This article reviews effects from plants to build scientific basis future lay groundwork developing functional foods prevention management linked disorders.
Language: Английский
Citations
14
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(6), P. 1595 - 1595
Published: May 25, 2023
Citrus cultivars have remarkable health benefits, but only the anti-inflammatory activities of major varieties been studied. This study investigated effects various citrus and their active components. The essential oils 21 peels were extracted via hydrodistillation using a Clevenger-type apparatus, chemical compositions analyzed. D-Limonene was most abundant constituent. To evaluate cultivars, gene expression levels an inflammatory mediator proinflammatory cytokines investigated. Among oils, those from C. japonica maxima exhibited superior activities, being able to inhibit mediators in lipopolysaccharide-stimulated RAW 264.7 cells. distinguished into seven distinct constituents, α-pinene, myrcene, D-limonene, β-ocimene, linalool, linalool oxide, α-terpineol, compared with other oils. single compounds significantly inhibited inflammation-related factors. In particular, α-terpineol effect. showed that exhibit high activity. addition, is compound contributes responses.
Language: Английский
Citations
18
Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(2), P. 112398 - 112398
Published: March 5, 2024
Language: Английский
Citations
4
BMC Complementary Medicine and Therapies, Journal Year: 2024, Volume and Issue: 24(1)
Published: July 10, 2024
Bitter orange (Citrus aurantium) is a fruiting shrub native to tropical and subtropical countries around the world cultivated in many regions due its nutraceutical value. The current study investigated metabolic profiling enzyme inhibitory activities of volatile constituents derived from C. aurantium peel Egypt by three different extraction methods.
Language: Английский
Citations
4
Journal of Essential Oil Bearing Plants, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 23
Published: Jan. 29, 2025
Language: Английский
Citations
0
Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16
Published: April 17, 2025
Essential oils, often referred to as "liquid gold," are renowned for their broad biological activity. Ancient Egyptians used essential oils' antibacterial and antiseptic effects preserve mummies, ancient Greeks olive oil sun protection, Chinese oils treat wounds. When applied the facial skin, potent anti-inflammatory, antioxidant, pharmacological characteristics provide various benefits, including sunscreen, skin-whitening, anti-aging effects. This paper aims summarize application of plant in skin whitening, antioxidant recent years, deeply analyzes internal relationship between modern drug delivery system, expounds how overcome limitations through specific enhance its activity stability, realize sustained release reduce potential toxicity, also discusses positive on brain function olfactory pathway, emphasizes possible safety risks use oil, puts forward corresponding suggestions use. Using keywords such "essential oils," "antioxidant," "anti-tyrosinase," Antibacterial Effects anti-inflammatory," "anti-anxiety," "drug carrier systems," a comprehensive search was conducted PubMed, CNKI, Baidu, Wanfang databases articles from past 5 years. Further screening performed select studies demonstrating efficacy topical or external application. Various showed strong oxidants, agents, anti-inflammatory skin-whitening agents. Combined with new it not only enhances but reduces inherent defects volatility, irritation, has targeted effect. At same time, integration into care products can make dual functions smell epidermal system nourish repair maximize oil. review delves systems, advocating broader natural resources technology. By strategically utilizing we promote sustainable development global economy. However, extensive clinical trials still required evaluate effectiveness systems.
Language: Английский
Citations
0
Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15
Published: July 25, 2024
Melasma, a prevalent pigmentary disorder, is characterized by its complex etiology, propensity for recurrence, and resistance to treatment. However, there currently no research on melasma through bibliometrics visualisation. This study analyses the hotspots trends in field based 2,709 publications from Web of Science Core Collection (WOSCC). We carried out bibliometric using Citespace software different countries/regions, institutions, authors, keywords. References were also analysed VoSviewer. The results indicate that overall, has been an increase related since 2014. According analysis collaborative network diagram, United States, Egyptian Knowledge Bank, Benjakul Soottawat are most contributing countries, respectively. Reference keyword have identified pathogenesis treatment as topic recent years. And how find new options more effective therapeutic drugs future trend. first visual melasma-related literature explore trends.
Language: Английский
Citations
3
Foods, Journal Year: 2024, Volume and Issue: 13(23), P. 3841 - 3841
Published: Nov. 28, 2024
In recent years, plant essential oils have been confirmed as natural inhibitors of foodborne pathogens. Citrus reticulata Blanco cv. Tankan peel oil (CPEO) showed anti-Listeria monocytogenes (LM) activities, and this study investigated the associated mechanisms by using high-resolution electron microscope, fluorescence spectrometer, flow cytometer, potentiometer, transcriptome sequencing. The results that CPEO restrained LM growth at a minimum inhibitory concentration 2% (v/v). anti-LM abilities were achieved disrupting permeability cell wall, damaging permeability, fluidity, integrity membrane, disturbing membrane hydrophobic core, destroying protein conformation. Moreover, could significantly inhibit aggregation from forming biofilm reducing extracellular polymeric substances’ (protein, polysaccharide, eDNA) production bacterial surface charge numbers. RNA sequencing data indicated genes involved in wall biosynthesis, DNA replication repair, quorum sensing two-component systems expressed differently after treatment. These suggested be used novel agent green preservative food sector. Further studies are needed to verify activities real food.
Language: Английский
Citations
3
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(9), P. 2269 - 2269
Published: Sept. 2, 2023
Agathis species are widely distributed around Southeast Asia, Australasia, South Pacific islands, and etc. Traditionally, have been used as the folk medicines, common ethnopharmacological uses of genus treatments headache myalgia. This study aims to investigate chemical composition dammara (Lamb.) Rich. leaf essential oil explore its antimelanogenesis effect. The constituents analyzed using gas chromatography-mass spectrometry (GC-MS), major sesquiterpenoids. δ-cadinene (16.12%), followed by γ-gurjunene (15.57%), 16-kaurene (12.43%), β-caryophyllene (8.58%), germacrene D (8.53%), γ-cadinene (5.33%). As for in vitro antityrosinase activity, inhibit tyrosinase activity mushroom when substrate is 3,4-dihydroxyphenylalanine (L-DOPA). Leaf prevents from acting diphenolase catalyzing L-DOPA dopaquinone, converting into dark melanin pigments. A. also exhibits vivo effect, reduces 43.48% formation zebrafish embryos at concentration 50 μg/mL. Results reveal has potential developing skin whitening drug depigmentation ingredient hyperpigmentary disorders.
Language: Английский
Citations
5
Molecules, Journal Year: 2023, Volume and Issue: 28(21), P. 7251 - 7251
Published: Oct. 24, 2023
Several studies have explored the biological activities of Citrus aurantium flowers, fruits, and seeds, but bioactivity C. leaves, which are treated as waste, remains unclear. Thus, this study developed a pilot-scale ultrasonic-assisted extraction process using Box–Behnken design (BBD) for optimized active compounds from their antityrosinase, antioxidant, antiaging, antimicrobial were evaluated. Under optimal conditions in 150× scaleup configuration (a 30 L ultrasonic machine) pilot plant, total phenolic content was 69.09 mg gallic acid equivalent/g dry weight, slightly lower (3.17%) than theoretical value. The half maximal inhibitory concentration leaf extract (CALE) 2,2-diphenyl-1-picrylhydrazyl–scavenging, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)–scavenging, anticollagenase, antielastase anti-matrix metalloprotein-1 123.5, 58.5, 181.3, 196.4, 216.3, 326.4 mg/L, respectively. Moreover, minimal concentrations bacteria fungi 150–350 500 In total, 17 detected CALE—with linalool, linalyl acetate, limonene, α-terpineol having highest concentrations. Finally, overall transdermal absorption permeation efficiency CALE 95.9%. conclusion, our demonstrated potential whitening, activities; it also nontoxic easily absorbed into skin well inexpensive to produce. Therefore, has applications various industries.
Language: Английский
Citations
5