Prevalence and determinants of post-COVID-19 syndrome among patients 6 months post-discharge from a teaching hospital in South India DOI Creative Commons
Binu Areekal,

Nayana K. Thumbayil,

T. E. Fathima Thasleema

et al.

Journal of Family Medicine and Primary Care, Journal Year: 2024, Volume and Issue: 13(4), P. 1454 - 1459

Published: April 1, 2024

The coronavirus disease 2019 (COVID-19) infection has affected millions of people worldwide in the last 4 years. Among those infected, long-term COVID-19 syndrome, which symptoms persist for a variable period, is posing new challenges to health system, but few studies are available India that examine post-COVID-19 is, 6 months and beyond infection. This study aimed find prevalence determinants syndrome among patients their

Language: Английский

The global prevalence of depression, anxiety, and sleep disorder among patients coping with Post COVID-19 syndrome (long COVID): a systematic review and meta-analysis DOI Creative Commons
Niloofar Seighali, Abolfazl Abdollahi, Arman Shafiee

et al.

BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)

Published: Feb. 6, 2024

Post COVID-19 syndrome, also known as "Long COVID," is a complex and multifaceted condition that affects individuals who have recovered from SARS-CoV-2 infection. This systematic review meta-analysis aim to comprehensively assess the global prevalence of depression, anxiety, sleep disorder in coping with syndrome.

Language: Английский

Citations

58

Sleep disturbance in post COVID-19 conditions: Prevalence and quality of life DOI Creative Commons
Rimawati Tedjasukmana, Astri Budikayanti, Wardah Rahmatul Islamiyah

et al.

Frontiers in Neurology, Journal Year: 2023, Volume and Issue: 13

Published: Jan. 9, 2023

Post COVID-19 conditions are complaints and symptoms in patients with a history of probable or confirmed after 3 months the onset last at least 2 months. About 10–20% people may experience post conditions, one which is sleep disturbance. There wide range prevalence disturbances from 6% to more than 70%. An online survey various countries showed that 78.58% subjects had disturbances, including insomnia, sleep-disordered breathing, central disorders hypersomnolence, circadian rhythm sleep-wake disorders, parasomnias, sleep-related movement disorders. Sleep disturbance can be found starting weeks until 48 discharge having negative test results. Women aged < 50 years old severe infection reported worse outcome. Several mechanisms cause condition, namely persistent viral inflammation, immunity dysregulation, mitochondrial dysfunction. studies discovered was major problem affected different domains QoL conditions. Significant correlation between several dimensions SF-36 moderate-to-severe insomnia Therefore, affect patients' QoL, existence should concern period. Further research required determine based on agreed definition as well methods assess this condition its impact QoL.

Language: Английский

Citations

56

Higher vulnerability to poor circadian light hygiene in individuals with a history of COVID-19 DOI
Denis Gubin,

Yu. V. Boldyreva,

Oliver Stefani

et al.

Chronobiology International, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 14

Published: Jan. 6, 2025

Seven-day actigraphy was performed within 1 month in 122 community-dwelling adults (mean age 24.40 y, 31 (25.4%) men) the same city of Tyumen, Russia. Groups with different COVID-19 status (present, COVID-19(+),

Language: Английский

Citations

3

Cognitive impairment after long COVID-19: current evidence and perspectives DOI Creative Commons
Zhitao Li, Zhen Zhang, Zhuoya Zhang

et al.

Frontiers in Neurology, Journal Year: 2023, Volume and Issue: 14

Published: July 31, 2023

COVID-19, caused by the SARS-CoV-2 virus, is a respiratory infectious disease. While most patients recover after treatment, there growing evidence that COVID-19 may result in cognitive impairment. Recent studies reveal some individuals experience deficits, such as diminished memory and attention, well sleep disturbances, suggesting could have long-term effects on function. Research indicates contribute to decline damaging crucial brain regions, including hippocampus anterior cingulate cortex. Additionally, identified active neuroinflammation, mitochondrial dysfunction, microglial activation patients, implying these factors be potential mechanisms leading Given findings, possibility of impairment following treatment warrants careful consideration. Large-scale follow-up are needed investigate impact function offer support clinical rehabilitation practices. In-depth neuropathological biological can elucidate precise provide theoretical basis for prevention, intervention research. Considering risks reinfection, it imperative integrate basic research data optimize preservation patients' quality life. This integration will also valuable insights responding similar public health events future. perspective article synthesizes discussing outlining future directions.

Language: Английский

Citations

39

Sleep Disturbances as a Consequence of Long COVID-19: Insights from Actigraphy and Clinimetric Examinations—An Uncontrolled Prospective Observational Pilot Study DOI Open Access
Wojciech Tański, Anna Tomasiewicz, Beata Jankowska‐Polańska

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(3), P. 839 - 839

Published: Feb. 1, 2024

The COVID-19 pandemic represents a global health and social challenge. However, the impact of SARS-CoV-2 infection itself on mental sleep quality remains poorly understood. purpose present uncontrolled prospective observational pilot study was to evaluate past disease incidence quantitative qualitative disturbances. A group 61 subjects (37 female, 24 male) reported disturbances that had lasted for at least one month started after recovery from COVID-19. used self-reported instruments: Epworth Sleepiness Scale (ESS) Insomnia Severity Index (ISI), as well an objective method—actigraphy—for analysis architecture. It shown most commonly (68.3%, n = 41) more than (83.6%, 51). ESS scores 7.8 ± 5.0 points indicate moderate daytime sleepiness, ISI 16.3 5.8 denote insomnia. were negatively correlated with total time in bed (r −0.3780, p 0.003), −0.2969, 0.020), wakefulness onset −0.2654, 0.039). In addition, respondents’ age (B −0.17, 0.000) onset. positive correlation found between −0.05, positively 0.3275, 0.010). Female gender be significant predictor insomnia’s severity 2.159, t 3.04, 0.004). conclusion, patients history report long-lasting do not subside spontaneously. patient studied, levels sleepiness insomnia found. frequently problems included irregular sleep, frequent awakenings, difficulty maintaining while normal duration preserved. These findings underscore need continued attention long-term consequences emphasize importance targeted interventions address these enduring affected individuals.

Language: Английский

Citations

10

Factors associated with mental health outcomes after COVID-19: A 24-month follow-up longitudinal study DOI Creative Commons
Hernan Felipe Guillén-Burgos,

Juan Francisco Gálvez-Flórez,

Sergio Moreno

et al.

General Hospital Psychiatry, Journal Year: 2023, Volume and Issue: 84, P. 241 - 249

Published: Sept. 1, 2023

Investigate the proportion of mental health outcomes (MHOs) and associated factors in COVID-19 survivors during a 24-month follow-up period.An observational, prospective study was performed teaching hospital Barranquilla, Colombia, from April 1, 2020, to August 30, 2022. A cohort 1565 recruited after discharge emergency room (ER), inpatient floor (IF), intensive care unit (ICU) services followed for 24 -months. The clinical assessment included screening scales symptoms anxiety, depressive, post-traumatic stress disorder (PTSD), insomnia. Sociodemographic were also collected identify possible factors. Descriptive, bivariate mixed random-effect linear models performed.A total patients included, whom 785 (50.35%) men. large with identified. After 24-months, proportions depression, PTSD, insomnia remained high at 16.55%, 21.79%, 35.27%, 23.86%, respectively. Social factors, location stays, physical comorbidities, severity significantly symptoms.COVID-19's 2-year deleterious impacts on health, as well variables influencing these findings, have been documented. These results should aid development public initiatives reduce morbidity rates post-COVID-19 patients.

Language: Английский

Citations

23

Fatigue, sleepiness and sleep quality are SARS-CoV-2 variant independent in patients with long COVID symptoms DOI Creative Commons

Anna Réka Percze,

Alexandra Nagy, Lőrinc Polivka

et al.

Inflammopharmacology, Journal Year: 2023, Volume and Issue: 31(6), P. 2819 - 2825

Published: April 5, 2023

Abstract Acute infections with SARS-CoV-2 variants of concerns (VOCs) differ in clinical presentation. Discrepancies their long-term sequelae, commonly referred to as long COVID, however, remain be explored. We retrospectively analyzed data 287 patients presented at the post-COVID care Pulmonology Department, Semmelweis University, Budapest, Hungary, and infected during a period 3 major epidemic waves Hungary (February–July 2021, VOC: B.1.1.7, Alpha, N = 135; August–December B.1.617.2, Delta, 89; January–June 2022, B.1.1.529, Omicron; 63), > 4 weeks after acute COVID-19. Overall, ratio COVID symptomatic (LC) asymptomatic (NS) was 2:1. Self-reported questionnaires on fatigue (Fatigue Severity Scale, FSS), sleepiness (Epworth Sleepiness ESS) sleep quality (Pittsburgh Sleep Quality Index, PSQI) showed higher scores for LC (4.79 ± 0.12, 7.45 0.33 7.46 0.27, respectively) than NS (2.85 0.16, 5.23 0.32 4.26 0.29, respectively; p < 0.05 all vs. LC). By comparing three waves, mean FSS PSQI patients, but not ESS scores, exceeded normal range all, no significant inter-wave differences. Considering ≥ 5 cutoff values, exhibited problematic (≥ 70%) poor (> 60%) waves. Comparative analysis component identified differences between Our findings highlight importance concerted efforts manage both disturbances patient care. This multifaceted approach should followed cases either VOCs SARS-CoV-2.

Language: Английский

Citations

21

Sleep Disturbance Severity and Correlates in Post-acute Sequelae of COVID-19 (PASC) DOI Open Access
Cinthya Pena-Orbea, Brittany Lapin, Yadi Li

et al.

Journal of General Internal Medicine, Journal Year: 2023, Volume and Issue: 38(8), P. 2015 - 2017

Published: April 4, 2023

Language: Английский

Citations

19

Prevalence of sleep disturbances in patients with long COVID assessed by standardised questionnaires and diagnostic criteria: A systematic review and meta-analysis DOI Creative Commons
Chotiman Chinvararak, Trudie Chalder

Journal of Psychosomatic Research, Journal Year: 2023, Volume and Issue: 175, P. 111535 - 111535

Published: Oct. 22, 2023

We aimed to study the prevalence of sleep disturbances in patients with long COVID-19.We conducted a systematic review and meta-analysis pooled post COVID-19. systematically searched relevant studies from three databases, including Medline, Embase Scopus. Original articles were included based on specific criteria: peer-reviewed, observational involving adults (18 or older) confirmed COVID-19 status through PCR testing focused context Exclusion criteria non-English articles, insufficient data, narrative/systematic reviews. The search was performed 31st July 2023 15th August 2023. identified 35 eligible papers; however, we excluded 6 which did not describe assessment. used random-effects model estimate disturbances.29 involved 13,935 patients; approximately 39% participants male aged 18 97 years. overall disturbance 46% (95% CI: 38-54%). Subgroup analyses revealed that poor quality 56% 47-65%). insomnia 38% 28-48%). Finally, excessive daytime sleepiness 14% 0-29%).Sleep are common patients. healthcare sector should recognise these issues provide an early, effective treatment prevent long-term sequelae problems.

Language: Английский

Citations

12

Sleep quality in individuals with post-COVID-19 condition: Relation with emotional, cognitive and functional variables DOI Creative Commons
Anna Carnes, Gerard Piñol‐Ripoll, Mar Ariza

et al.

Brain Behavior & Immunity - Health, Journal Year: 2023, Volume and Issue: 35, P. 100721 - 100721

Published: Dec. 31, 2023

The study aimed to assess sleep quality in PCC patients and its predictors by analysing relationship with emotional, cognitive functional variables, as well possible differences based on COVID-19 severity. We included 368 individuals 123 healthy controls (HCs) from the NAUTILUS Project (NCT05307549 NCT05307575). assessed (Pittsburgh Sleep Quality Index, PSQI), anxiety (Generalized Anxiety Disorder, GAD-7), depression (Patient Health Questionnaire, PHQ-9), global cognition (Montreal Cognitive Assessment, MoCA), everyday memory failures (Memory Failures of Everyday MFE-30), fatigue (Chadler Fatigue CFQ), life (European Life-5 Dimensions, EQ-5D), physical activity levels (International Physical Activity IPAQ). 203 were nonhospitalized, 83 hospitalized 82 admitted intensive care unit (ICU). found statistically significant PSQI total score between HC groups (p < 0.0001), but there no among groups. In multiple linear regressions, PHQ-9 was a predictor poor for mild = 0.003); GAD-7 0.032) EQ-5D 0.011) scores group; 0.045) IPAQ 0.005) group ICU-PCC. These results indicate that worse is related higher anxiety, less activity. Therapeutic strategies should focus these factors have positive impact sleep.

Language: Английский

Citations

10