Journal of Family Medicine and Primary Care,
Journal Year:
2024,
Volume and Issue:
13(4), P. 1454 - 1459
Published: April 1, 2024
The
coronavirus
disease
2019
(COVID-19)
infection
has
affected
millions
of
people
worldwide
in
the
last
4
years.
Among
those
infected,
long-term
COVID-19
syndrome,
which
symptoms
persist
for
a
variable
period,
is
posing
new
challenges
to
health
system,
but
few
studies
are
available
India
that
examine
post-COVID-19
is,
6
months
and
beyond
infection.
This
study
aimed
find
prevalence
determinants
syndrome
among
patients
their
BMC Psychiatry,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Feb. 6, 2024
Post
COVID-19
syndrome,
also
known
as
"Long
COVID,"
is
a
complex
and
multifaceted
condition
that
affects
individuals
who
have
recovered
from
SARS-CoV-2
infection.
This
systematic
review
meta-analysis
aim
to
comprehensively
assess
the
global
prevalence
of
depression,
anxiety,
sleep
disorder
in
coping
with
syndrome.
Frontiers in Neurology,
Journal Year:
2023,
Volume and Issue:
13
Published: Jan. 9, 2023
Post
COVID-19
conditions
are
complaints
and
symptoms
in
patients
with
a
history
of
probable
or
confirmed
after
3
months
the
onset
last
at
least
2
months.
About
10–20%
people
may
experience
post
conditions,
one
which
is
sleep
disturbance.
There
wide
range
prevalence
disturbances
from
6%
to
more
than
70%.
An
online
survey
various
countries
showed
that
78.58%
subjects
had
disturbances,
including
insomnia,
sleep-disordered
breathing,
central
disorders
hypersomnolence,
circadian
rhythm
sleep-wake
disorders,
parasomnias,
sleep-related
movement
disorders.
Sleep
disturbance
can
be
found
starting
weeks
until
48
discharge
having
negative
test
results.
Women
aged
<
50
years
old
severe
infection
reported
worse
outcome.
Several
mechanisms
cause
condition,
namely
persistent
viral
inflammation,
immunity
dysregulation,
mitochondrial
dysfunction.
studies
discovered
was
major
problem
affected
different
domains
QoL
conditions.
Significant
correlation
between
several
dimensions
SF-36
moderate-to-severe
insomnia
Therefore,
affect
patients'
QoL,
existence
should
concern
period.
Further
research
required
determine
based
on
agreed
definition
as
well
methods
assess
this
condition
its
impact
QoL.
Chronobiology International,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 14
Published: Jan. 6, 2025
Seven-day
actigraphy
was
performed
within
1
month
in
122
community-dwelling
adults
(mean
age
24.40
y,
31
(25.4%)
men)
the
same
city
of
Tyumen,
Russia.
Groups
with
different
COVID-19
status
(present,
COVID-19(+),
Frontiers in Neurology,
Journal Year:
2023,
Volume and Issue:
14
Published: July 31, 2023
COVID-19,
caused
by
the
SARS-CoV-2
virus,
is
a
respiratory
infectious
disease.
While
most
patients
recover
after
treatment,
there
growing
evidence
that
COVID-19
may
result
in
cognitive
impairment.
Recent
studies
reveal
some
individuals
experience
deficits,
such
as
diminished
memory
and
attention,
well
sleep
disturbances,
suggesting
could
have
long-term
effects
on
function.
Research
indicates
contribute
to
decline
damaging
crucial
brain
regions,
including
hippocampus
anterior
cingulate
cortex.
Additionally,
identified
active
neuroinflammation,
mitochondrial
dysfunction,
microglial
activation
patients,
implying
these
factors
be
potential
mechanisms
leading
Given
findings,
possibility
of
impairment
following
treatment
warrants
careful
consideration.
Large-scale
follow-up
are
needed
investigate
impact
function
offer
support
clinical
rehabilitation
practices.
In-depth
neuropathological
biological
can
elucidate
precise
provide
theoretical
basis
for
prevention,
intervention
research.
Considering
risks
reinfection,
it
imperative
integrate
basic
research
data
optimize
preservation
patients'
quality
life.
This
integration
will
also
valuable
insights
responding
similar
public
health
events
future.
perspective
article
synthesizes
discussing
outlining
future
directions.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(3), P. 839 - 839
Published: Feb. 1, 2024
The
COVID-19
pandemic
represents
a
global
health
and
social
challenge.
However,
the
impact
of
SARS-CoV-2
infection
itself
on
mental
sleep
quality
remains
poorly
understood.
purpose
present
uncontrolled
prospective
observational
pilot
study
was
to
evaluate
past
disease
incidence
quantitative
qualitative
disturbances.
A
group
61
subjects
(37
female,
24
male)
reported
disturbances
that
had
lasted
for
at
least
one
month
started
after
recovery
from
COVID-19.
used
self-reported
instruments:
Epworth
Sleepiness
Scale
(ESS)
Insomnia
Severity
Index
(ISI),
as
well
an
objective
method—actigraphy—for
analysis
architecture.
It
shown
most
commonly
(68.3%,
n
=
41)
more
than
(83.6%,
51).
ESS
scores
7.8
±
5.0
points
indicate
moderate
daytime
sleepiness,
ISI
16.3
5.8
denote
insomnia.
were
negatively
correlated
with
total
time
in
bed
(r
−0.3780,
p
0.003),
−0.2969,
0.020),
wakefulness
onset
−0.2654,
0.039).
In
addition,
respondents’
age
(B
−0.17,
0.000)
onset.
positive
correlation
found
between
−0.05,
positively
0.3275,
0.010).
Female
gender
be
significant
predictor
insomnia’s
severity
2.159,
t
3.04,
0.004).
conclusion,
patients
history
report
long-lasting
do
not
subside
spontaneously.
patient
studied,
levels
sleepiness
insomnia
found.
frequently
problems
included
irregular
sleep,
frequent
awakenings,
difficulty
maintaining
while
normal
duration
preserved.
These
findings
underscore
need
continued
attention
long-term
consequences
emphasize
importance
targeted
interventions
address
these
enduring
affected
individuals.
General Hospital Psychiatry,
Journal Year:
2023,
Volume and Issue:
84, P. 241 - 249
Published: Sept. 1, 2023
Investigate
the
proportion
of
mental
health
outcomes
(MHOs)
and
associated
factors
in
COVID-19
survivors
during
a
24-month
follow-up
period.An
observational,
prospective
study
was
performed
teaching
hospital
Barranquilla,
Colombia,
from
April
1,
2020,
to
August
30,
2022.
A
cohort
1565
recruited
after
discharge
emergency
room
(ER),
inpatient
floor
(IF),
intensive
care
unit
(ICU)
services
followed
for
24
-months.
The
clinical
assessment
included
screening
scales
symptoms
anxiety,
depressive,
post-traumatic
stress
disorder
(PTSD),
insomnia.
Sociodemographic
were
also
collected
identify
possible
factors.
Descriptive,
bivariate
mixed
random-effect
linear
models
performed.A
total
patients
included,
whom
785
(50.35%)
men.
large
with
identified.
After
24-months,
proportions
depression,
PTSD,
insomnia
remained
high
at
16.55%,
21.79%,
35.27%,
23.86%,
respectively.
Social
factors,
location
stays,
physical
comorbidities,
severity
significantly
symptoms.COVID-19's
2-year
deleterious
impacts
on
health,
as
well
variables
influencing
these
findings,
have
been
documented.
These
results
should
aid
development
public
initiatives
reduce
morbidity
rates
post-COVID-19
patients.
Inflammopharmacology,
Journal Year:
2023,
Volume and Issue:
31(6), P. 2819 - 2825
Published: April 5, 2023
Abstract
Acute
infections
with
SARS-CoV-2
variants
of
concerns
(VOCs)
differ
in
clinical
presentation.
Discrepancies
their
long-term
sequelae,
commonly
referred
to
as
long
COVID,
however,
remain
be
explored.
We
retrospectively
analyzed
data
287
patients
presented
at
the
post-COVID
care
Pulmonology
Department,
Semmelweis
University,
Budapest,
Hungary,
and
infected
during
a
period
3
major
epidemic
waves
Hungary
(February–July
2021,
VOC:
B.1.1.7,
Alpha,
N
=
135;
August–December
B.1.617.2,
Delta,
89;
January–June
2022,
B.1.1.529,
Omicron;
63),
>
4
weeks
after
acute
COVID-19.
Overall,
ratio
COVID
symptomatic
(LC)
asymptomatic
(NS)
was
2:1.
Self-reported
questionnaires
on
fatigue
(Fatigue
Severity
Scale,
FSS),
sleepiness
(Epworth
Sleepiness
ESS)
sleep
quality
(Pittsburgh
Sleep
Quality
Index,
PSQI)
showed
higher
scores
for
LC
(4.79
±
0.12,
7.45
0.33
7.46
0.27,
respectively)
than
NS
(2.85
0.16,
5.23
0.32
4.26
0.29,
respectively;
p
<
0.05
all
vs.
LC).
By
comparing
three
waves,
mean
FSS
PSQI
patients,
but
not
ESS
scores,
exceeded
normal
range
all,
no
significant
inter-wave
differences.
Considering
≥
5
cutoff
values,
exhibited
problematic
(≥
70%)
poor
(>
60%)
waves.
Comparative
analysis
component
identified
differences
between
Our
findings
highlight
importance
concerted
efforts
manage
both
disturbances
patient
care.
This
multifaceted
approach
should
followed
cases
either
VOCs
SARS-CoV-2.
Journal of Psychosomatic Research,
Journal Year:
2023,
Volume and Issue:
175, P. 111535 - 111535
Published: Oct. 22, 2023
We
aimed
to
study
the
prevalence
of
sleep
disturbances
in
patients
with
long
COVID-19.We
conducted
a
systematic
review
and
meta-analysis
pooled
post
COVID-19.
systematically
searched
relevant
studies
from
three
databases,
including
Medline,
Embase
Scopus.
Original
articles
were
included
based
on
specific
criteria:
peer-reviewed,
observational
involving
adults
(18
or
older)
confirmed
COVID-19
status
through
PCR
testing
focused
context
Exclusion
criteria
non-English
articles,
insufficient
data,
narrative/systematic
reviews.
The
search
was
performed
31st
July
2023
15th
August
2023.
identified
35
eligible
papers;
however,
we
excluded
6
which
did
not
describe
assessment.
used
random-effects
model
estimate
disturbances.29
involved
13,935
patients;
approximately
39%
participants
male
aged
18
97
years.
overall
disturbance
46%
(95%
CI:
38-54%).
Subgroup
analyses
revealed
that
poor
quality
56%
47-65%).
insomnia
38%
28-48%).
Finally,
excessive
daytime
sleepiness
14%
0-29%).Sleep
are
common
patients.
healthcare
sector
should
recognise
these
issues
provide
an
early,
effective
treatment
prevent
long-term
sequelae
problems.
Brain Behavior & Immunity - Health,
Journal Year:
2023,
Volume and Issue:
35, P. 100721 - 100721
Published: Dec. 31, 2023
The
study
aimed
to
assess
sleep
quality
in
PCC
patients
and
its
predictors
by
analysing
relationship
with
emotional,
cognitive
functional
variables,
as
well
possible
differences
based
on
COVID-19
severity.
We
included
368
individuals
123
healthy
controls
(HCs)
from
the
NAUTILUS
Project
(NCT05307549
NCT05307575).
assessed
(Pittsburgh
Sleep
Quality
Index,
PSQI),
anxiety
(Generalized
Anxiety
Disorder,
GAD-7),
depression
(Patient
Health
Questionnaire,
PHQ-9),
global
cognition
(Montreal
Cognitive
Assessment,
MoCA),
everyday
memory
failures
(Memory
Failures
of
Everyday
MFE-30),
fatigue
(Chadler
Fatigue
CFQ),
life
(European
Life-5
Dimensions,
EQ-5D),
physical
activity
levels
(International
Physical
Activity
IPAQ).
203
were
nonhospitalized,
83
hospitalized
82
admitted
intensive
care
unit
(ICU).
found
statistically
significant
PSQI
total
score
between
HC
groups
(p
<
0.0001),
but
there
no
among
groups.
In
multiple
linear
regressions,
PHQ-9
was
a
predictor
poor
for
mild
=
0.003);
GAD-7
0.032)
EQ-5D
0.011)
scores
group;
0.045)
IPAQ
0.005)
group
ICU-PCC.
These
results
indicate
that
worse
is
related
higher
anxiety,
less
activity.
Therapeutic
strategies
should
focus
these
factors
have
positive
impact
sleep.