International Journal of Polymer Science,
Journal Year:
2021,
Volume and Issue:
2021, P. 1 - 20
Published: Sept. 8, 2021
As
a
technique
of
producing
fabric
engineering
scaffolds,
three-dimensional
(3D)
printing
has
tremendous
possibilities.
3D
applications
are
restricted
to
wide
range
biomaterials
in
the
field
regenerative
medicine
and
tissue
engineering.
Due
their
biocompatibility,
bioactiveness,
biodegradability,
biopolymers
such
as
collagen,
alginate,
silk
fibroin,
chitosan,
cellulose,
starch
used
variety
fields,
including
food,
biomedical,
regeneration,
agriculture,
packaging,
pharmaceutical
industries.
The
benefits
3D-printed
scaffolds
many,
capacity
produce
complicated
geometries,
porosity,
multicell
coculture
take
growth
factors
into
account.
In
particular,
additional
production
offers
new
options
structures
materials
with
specialised
patterns
properties.
realm
(TERM),
important
progress
been
accomplished;
now,
several
state-of-the-art
techniques
porous
for
organ
or
regeneration
be
suited
technology.
Natural
biopolymeric
often
better
designing
manufacturing
healing
equipment
than
temporary
implants
owing
its
appropriate
properties
biocompatibility.
review
focuses
on
additive
significant
changes,
advancements,
trends,
developments
potential
applications.
Polymers,
Journal Year:
2021,
Volume and Issue:
13(7), P. 1105 - 1105
Published: March 30, 2021
Tissue
engineering
(TE)
and
regenerative
medicine
integrate
information
technology
from
various
fields
to
restore/replace
tissues
damaged
organs
for
medical
treatments.
To
achieve
this,
scaffolds
act
as
delivery
vectors
or
cellular
systems
drugs
cells;
thereby,
material
is
able
colonize
host
cells
sufficiently
meet
up
the
requirements
of
regeneration
repair.
This
process
multi-stage
requires
development
components
create
desired
neo-tissue
organ.
In
several
current
TE
strategies,
biomaterials
are
essential
components.
While
polymers
established
their
use
biomaterials,
careful
consideration
environment
interactions
needed
required
in
selecting
a
polymer
given
application.
Depending
on
scaffold
materials
can
be
natural
synthetic
origin,
degradable
nondegradable.
this
review,
an
overview
possible
composite
with
physicochemical
properties
including
biocompatibility,
biodegradability,
morphology,
mechanical
strength,
pore
size,
porosity
discussed.
The
fabrication
techniques
few
commercially
available
biopolymers
also
tabulated.
Journal of Science Advanced Materials and Devices,
Journal Year:
2020,
Volume and Issue:
5(1), P. 1 - 9
Published: Feb. 7, 2020
Globally,
bone
fractures
due
to
osteoporosis
occur
every
20
s
in
people
aged
over
50
years.
The
significant
healthcare
costs
required
manage
this
problem
are
further
exacerbated
by
the
long
healing
times
experienced
with
current
treatment
practices.
Novel
approaches
such
as
tissue
engineering,
is
using
biomaterial
scaffolds
stimulate
and
guide
regeneration
of
damaged
that
cannot
heal
spontaneously.
Scaffolds
provide
a
three-dimensional
network
mimics
extra
cellular
micro-environment
supporting
viability,
attachment,
growth
migration
cells
whilst
maintaining
structure
regenerated
vivo.
osteogenic
capability
scaffold
influenced
interconnections
between
pores
which
facilitate
cell
distribution,
integration
host
capillary
ingrowth.
Hence,
preparation
applicable
pore
size
interconnectivity
issue
engineering.
To
be
effective
however
vivo,
must
also
cope
requirements
for
physiological
mechanical
loading.
This
review
focuses
on
relationship
porosity
subsequent
osteogenesis,
vascularisation
degradation
during
regeneration.
Advanced Functional Materials,
Journal Year:
2021,
Volume and Issue:
31(21)
Published: March 8, 2021
Abstract
Bone
tissue
engineering
(BTE)
is
a
rapidly
growing
field
aiming
to
create
biofunctional
that
can
integrate
and
degrade
in
vivo
treat
diseased
or
damaged
tissue.
It
has
become
evident
scaffold
fabrication
techniques
are
very
important
dictating
the
final
structural,
mechanical
properties,
biological
response
of
implanted
biomaterials.
A
comprehensive
review
current
accomplishments
on
techniques,
their
structure,
function
properties
for
BTE
provided
herein.
Different
types
biomaterials
ranging
from
inorganic
natural
synthetic
polymers
related
composites
processing
presented.
Emergent
scaffolding
such
as
electrospinning,
freeze‐drying,
bioprinting,
decellularization
also
discussed.
Strategies
improve
vascularization
potential
immunomodulation,
which
considered
grand
challenge
scaffolding,
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology,
Journal Year:
2020,
Volume and Issue:
12(4)
Published: March 12, 2020
Abstract
This
review
provides
insights
into
the
current
advancements
in
field
of
electrospinning,
focusing
on
its
applications
for
skin
tissue
engineering.
Furthermore,
it
reports
evolvement
and
present
challenges
advanced
substitute
product
development
explores
recent
contributions
2D
3D
scaffolding,
natural,
synthetic,
composite
nanomaterials.
In
past
decades,
nanotechnology
has
arisen
as
a
fascinating
discipline
that
influenced
every
aspect
science,
engineering,
medicine.
Electrospinning
is
versatile
fabrication
method
allows
researchers
to
elicit
explore
many
faced
by
engineering
regenerative
electrospun
nanofibers
are
particularly
attractive
due
their
refined
morphology,
processing
flexibility—that
formation
unique
materials
structures,
extracellular
matrix‐like
biomimetic
architecture.
These
allow
promote
improved
re‐epithelization
neo‐tissue
wounds.
Advancements
use
portable
electrospinning
equipment
employment
transdermal
drug
delivery
melanoma
treatment
additionally
explored.
Present
trends
issues
critically
discussed
based
recently
published
patents,
clinical
trials,
vivo
studies.
article
categorized
under:
Implantable
Materials
Surgical
Technologies
>
Nanotechnology
Tissue
Repair
Replacement
Therapeutic
Approaches
Drug
Discovery
Emerging
Nanomaterials
Implants
RSC Advances,
Journal Year:
2020,
Volume and Issue:
10(56), P. 33782 - 33835
Published: Jan. 1, 2020
Sol–gel
derived
bioactive
glasses
have
been
extensively
explored
as
a
promising
and
highly
porous
scaffold
materials
for
bone
tissue
regeneration
applications
owing
to
their
exceptional
osteoconductivity,
osteostimulation
degradation
rates.
International Journal of Molecular Sciences,
Journal Year:
2021,
Volume and Issue:
22(2), P. 903 - 903
Published: Jan. 18, 2021
Shortcomings
related
to
the
treatment
of
bone
diseases
and
consequent
tissue
regeneration
such
as
transplants
have
been
addressed
some
extent
by
engineering
regenerative
medicine.
Tissue
has
promoted
structures
that
can
simulate
extracellular
matrix
are
capable
guiding
natural
repair
using
signaling
molecules
promote
osteoinduction
angiogenesis
essential
in
formation
new
tissues.
Although
recent
studies
on
developing
novel
growth
factor
delivery
systems
for
attracted
great
attention,
taking
into
account
complexity
matrix,
scaffolding
factors
should
not
be
explored
independently.
Consequently,
combine
both
concepts
potential
effectiveness
methods.
In
this
review,
developments
simultaneously
consider
covered
detail.
The
main
emphasis
overview
is
strategies
employ
polymer-based
scaffolds
spatiotemporal-controlled
single
multiple
bone-regeneration
approaches.
From
clinical
applications
creating
alternative
structural
materials,
advancing
constantly,
it
relevant
regularly
update
topics.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2022,
Volume and Issue:
10
Published: April 25, 2022
Reproduction
of
different
tissues
using
scaffolds
and
materials
is
a
major
element
in
regenerative
medicine.
The
regeneration
whole
organs
with
decellularized
extracellular
matrix
(dECM)
has
remained
goal
despite
the
use
these
for
purposes.
Recently,
decellularization
techniques
have
been
widely
used
producing
that
are
appropriate
regenerating
damaged
may
be
able
to
overcome
shortage
donor
organs.
Decellularized
ECM
offers
several
advantages
over
synthetic
compounds,
including
preserved
natural
microenvironment
features.
Different
methods
developed,
each
which
removing
cells
from
specific
under
certain
conditions.
A
variety
advanced
evaluating
process
terms
cell
removal
efficiency,
tissue
ultrastructure
preservation,
toxicity,
biocompatibility,
biodegradability,
mechanical
resistance
order
enhance
efficacy
methods.
Modification
improve
characteristics
scaffolds,
making
them
available
tissues.
Moreover,
modification
makes
options
drug
delivery,
disease
modeling,
improving
stem
growth
proliferation.
However,
considering
challenges
way
application
this
field
constantly
developing
progressively
moving
forward.
This
review
outlined
recent
sterilization
strategies,
evaluation
tests
efficient
decellularization,
processing,
application,
future
outlooks
medicine
engineering.
Polymers,
Journal Year:
2020,
Volume and Issue:
12(4), P. 844 - 844
Published: April 6, 2020
Polymer
scaffolds
constitute
a
very
interesting
strategy
for
tissue
engineering.
Even
though
they
are
generally
non-toxic,
in
some
cases,
may
not
provide
suitable
support
cell
adhesion,
proliferation,
and
differentiation,
which
decelerates
regeneration.
To
improve
biological
properties,
frequently
enriched
with
bioactive
molecules,
inter
alia
extracellular
matrix
proteins,
adhesive
peptides,
growth
factors,
hormones,
cytokines.
Although
there
many
papers
describing
synthesis
properties
of
polymer
proteins
or
few
reviews
comprehensively
summarize
these
molecules.
Thus,
this
review
presents
the
current
knowledge
about
most
important
peptides
used
modification
This
paper
also
describes
influence
addition
on
physicochemical,
mechanical,
scaffolds.
Moreover,
article
sums
up
major
applications
biodegradable
natural
synthetic
modified
have
been
developed
within
past
five
years.
