Advantages of animal leather over alternatives and its medical applications

European Polymer Journal, Journal Year: 2024, Volume and Issue: 214, P. 113153 - 113153

Published: May 18, 2024

The leather industry, grounded in ancient practices, utilizes animal skins composed of collagen protein polymer as materials. This versatile animal-based material is crucial for crafting items like shoes, clothing, and car interiors. While has faced criticisms environmental challenges the production process, including wastewater solid waste generation, well concerns about ethics, it holds numerous merits compared to synthetic plant-based vegan leather. paper reviews advantages its potential medical application. widespread use reveals that, despite passage time, remains an important humans. benefits leather, comparison encompass biodegradability, biocompatibility, natural feel aesthetics, breathability, durability, longevity. Animal-based been utilized various applications, pharmaceuticals, sensors, implants. These could make more suitable manufacturing implants alternatives. Therefore, this suggests further development equipment materials based on promote human health.

Language: Английский

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The hidden cost of illicit trade: Evaluating the physiological health of smuggled European glass eels (Anguilla anguilla)

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 960, P. 178346 - 178346

Published: Jan. 1, 2025

Language: Английский

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The use of acellular fish skin grafts in burns and complex trauma wounds: a systematic review of clinical data

Plastic and Aesthetic Research, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 23, 2024

Aim: In the field of burns and soft tissue reconstruction, skin substitutes have been successfully used for various indications. They allow conservative treatment as well temporal coverage through improvement wound bed conditions, pathogen control formation new tissue. Fish grafts (FSGs) gained rising attention a tool in substitute market. This systematic review aims to provide an update on clinical studies investigating effects FSG healing following indications: donor sites split-thickness grafts, superficial deep partial-thickness burns, full-thickness combat wounds, other acute wounds. Methods: A peer-reviewed literature available January 2024 was conducted examine burn complex trauma using databases PubMed Web Science. Only published English were included. Results: total, 11 considered eligible therefore included present review. According data, main advantages two commonly types FSGs (Kerecis® Omega3 Wound Matrix Nile tilapia) are acceleration re-epithelialization time, reduction pain intensity infection rates, number required dressing changes. Conclusion: represent safe promising product management sites, However, there is paucity high-quality evidence, especially randomized controlled trials. More research needed fully understand product’s potential create more meaningful algorithm.

Language: Английский

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Applications of tandem mass spectrometry (MS/MS) in antimicrobial peptides field: Current state and new applications

Heliyon, Journal Year: 2024, Volume and Issue: 10(7), P. e28484 - e28484

Published: March 31, 2024

Antimicrobial peptides (AMPs) constitute a group of small molecular that exhibit wide range antimicrobial activity. These are abundantly present in the innate immune system various organisms. Given rise multidrug-resistant bacteria, microbiological studies have identified AMPs as potential natural antibiotics. In context resistance across human pathogens, hold considerable promise for clinical applications. However, numerous challenges exist detection AMPs, particularly by immunological and biological methods, especially when studying newly discovered proteomics. This review outlines current status research strategies employed their development, considering resent discoveries methodologies. Subsequently, we focus on advanced techniques mass spectrometry quantification diverse samples, analyzes application, advantages, limitations. Additionally, propose suggestions future development tandem AMPs.

Language: Английский

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Revealing Metabolic Dysregulation Induced by Polypropylene Nano- and Microplastics in Nile Tilapia via Noninvasive Probing Epidermal Mucus

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(23), P. 9416 - 9423

Published: May 29, 2024

A noninvasive sampling technology was conceived, employing a disposable acupuncture needle in conjunction with high-resolution mass spectrometry (termed as direct extractive electrospray ionization spectrometry, NIDS-EESI-MS) to scrutinize the epidermal mucus of Nile tilapia for insights into metabolic dysregulation induced by polypropylene nano- and microplastics. This analytical method initiates dispensing an extraction solvent onto needles coated sample, almost simultaneously applying high voltage generate analyte ions. innovative strategy obliterates necessitation laborious sample preparation, thereby simplifying process. Employing this technique facilitated delineation plethora metabolites, encompassing, but not confined to, amino acids, peptides, carbohydrates, ketones, fatty their derivatives. Follow-up pathway enrichment analysis exposed notable alterations within key pathways, including biosynthesis phenylalanine, tyrosine, tryptophan, lysine degradation, well metabolism valine, leucine, isoleucine pathways tilapia, consequent increased concentrations nanoplastics. These portend potential implications such immune suppression, among other deleterious outcomes. trailblazing application methodology only spares aquatic life from sacrifice also inaugurates ethical paradigm conducting longitudinal studies on same organisms, facilitating detailed investigations long-term effects environmental pollutants. enhances ability observe understand subtle yet significant impacts contaminants over time.

Language: Английский

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Exploring the Bioactive Properties and Potential Probionts in the Fish Mucosa

Journal of Bacteriology and Virology, Journal Year: 2025, Volume and Issue: 55(1), P. 26 - 41

Published: March 31, 2025

Language: Английский

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Effect of fish meal substitution with trout viscera protein hydrolysate on the innate immune response of red tilapia (Oreochromis spp)

Fish Physiology and Biochemistry, Journal Year: 2025, Volume and Issue: 51(2)

Published: Feb. 27, 2025

Abstract This study evaluated the effect of replacing fish meal (FM) with concentrated trout viscera protein hydrolysate (TVPH) on immune response in juvenile red tilapia ( Oreocheromis spp). Five isoenergetic and isoproteic experimental diets were prepared by substituting FM TVPH at different substitution ratios: 0% (control, D1) 25% (D2), 50% (D3), 75% (D4), 100% (D5). A total 180 distributed 15 tanks. Fish from three tanks fed daily 2% biomass for 25 days one five mentioned above. At end trial, counted, weighed, measured, skin mucus serum samples obtained to parameters related humoral immunity. The results indicate a survival rate all groups did not show significant differences terms growth feed efficiency. On other hand, D2 D3 had significantly higher values. Also, or D5 lysozyme activity diet also immunoglobulin levels than control diet. In mucus, D4 showed fish. However, anti-protease bactericidal decreased diets, respectively. These demonstrate that positively modulate compared

Language: Английский

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Recent Advances in Polypeptide Antibiotics Derived from Marine Microorganisms

Marine Drugs, Journal Year: 2023, Volume and Issue: 21(10), P. 547 - 547

Published: Oct. 22, 2023

In the post-antibiotic era, rapid development of antibiotic resistance and shortage available antibiotics are triggering a new health-care crisis. The discovery novel potent to extend pipeline is urgent. Small-molecule antimicrobial peptides have wide variety spectra multiple innovative mechanisms due their rich structural diversity. Consequently, they become research hotspot considered be promising candidates for next-generation antibiotics. Therefore, we compiled collection small-molecule derived from marine microorganisms last fifteen years show recent advances in this field. We categorize these compounds into three classes—cyclic oligopeptides, cyclic depsipeptides, lipopeptides—according features, present sources, structures, spectrums, with discussion structure activity relationships action some compounds.

Language: Английский

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A review of soluble factors and receptors involved in fish skin immunity: The tip of the iceberg

Fish & Shellfish Immunology, Journal Year: 2023, Volume and Issue: 145, P. 109311 - 109311

Published: Dec. 19, 2023

The immune system of fish possesses soluble factors, receptors, pathways and cells very similar to those the other vertebrates' system. Throughout evolutionary history, exocrine secretions organisms have accumulated a large reservoir factors that serve protect from microbial pathogens could disrupt mucosal barrier homeostasis. In parallel, diverse set recognition molecules been discovered alert organism presence pathogens. known functions both receptors mentioned above encompass critical aspects host defense, such as pathogen binding neutralization, opsonization, or modulation inflammation if present. cooperate are able initiate most appropriate response in an attempt eliminate before infection can begin. Furthermore, these molecules, working coordination with defence collaboratively erect robust perfectly coordinated complementary specificity, activity tissue distribution. This intricate network constitutes immensely effective mechanism for fish. this context, present review focuses on some main studied last decade skin mucosa teleost However, knowledge is still limited all teleosts. Therefore, further studies suggested throughout would help better understand which proteins involved.

Language: Английский

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Effect of dietary inclusion of microalgae (Nannochloropsis gaditana and Schizochytrium spp) on non-specific immunity and erythrocyte maturity in Atlantic salmon fingerlings

Fish & Shellfish Immunology, Journal Year: 2023, Volume and Issue: 140, P. 108975 - 108975

Published: July 22, 2023

Language: Английский

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