Effects of Probiotics on Gut Microbiota: An Overview

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 6022 - 6022

Published: May 30, 2024

The role of probiotics in regulating intestinal flora to enhance host immunity has recently received widespread attention. Altering the human gut microbiota may increase predisposition several disease phenotypes such as inflammation and metabolic disorders. converts dietary nutrients into metabolites that serve biologically active molecules modulating regulatory functions host. Probiotics, which are microorganisms, play a versatile restoring composition microbiota, helping improve prevent phenotypes. This comprehensive review provides firsthand information on their influence health, effects diet how alter function along with corresponding building healthy intestine. We also discuss implications some most important diseases. In summary, significant boosting overall immunity, increasing abundance beneficial bacteria, ameliorate symptoms multiple

Language: Английский

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Biotherapy Using Probiotics as Therapeutic Agents to Restore the Gut Microbiota to Relieve Gastrointestinal Tract Inflammation, IBD, IBS and Prevent Induction of Cancer

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(6), P. 5748 - 5748

Published: March 17, 2023

The gut microbiota is composed of several microbial strains with diverse and variable compositions in both healthy sick people. An undisturbed needs to be sustained order perform all physiological, metabolic, immune functions a normal way prevent the development diseases. This article has reviewed published information on issue disruption balance microbiota. could for many reasons, such as infection gastrointestinal tract, food poisoning, diarrhoea, chemotherapy, malnutrition, lifestyle, ageing. If this not restored normal, it might cause dysbiosis. Eventually, interrupted by dysbiosis initiate health issues, inflammation induction cancer, progression variety diseases irritable bowel syndrome inflammatory disease. review concluded that biotherapy natural using probiotic products, whether form food, beverages, or supplements, restore disrupted Metabolites secreted ingested probiotics help relieve tract can avoid cancer.

Language: Английский

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Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(2), P. 217 - 217

Published: Feb. 18, 2024

Infectious diseases have long posed a significant threat to global health and require constant innovation in treatment approaches. However, recent groundbreaking research has shed light on previously overlooked player the pathogenesis of disease-the human microbiome. This review article addresses intricate relationship between microbiome infectious unravels its role as crucial mediator host-pathogen interactions. We explore remarkable potential harnessing this dynamic ecosystem develop innovative strategies that could revolutionize management diseases. By exploring latest advances emerging trends, aims provide new perspective combating by targeting

Language: Английский

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A Comprehensive Review of the Triangular Relationship among Diet–Gut Microbiota–Inflammation

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(17), P. 9366 - 9366

Published: Aug. 29, 2024

The human gastrointestinal tract hosts a complex and dynamic community of microorganisms known as the gut microbiota, which play pivotal role in numerous physiological processes, including digestion, metabolism, immune function. Recent research has highlighted significant impact diet on microbiota composition functionality, consequential effects host health. Concurrently, there is growing evidence linking to inflammation, key factor many chronic diseases such inflammatory bowel disease (IBD), obesity, diabetes, cardiovascular (CVDs). This review explores how dietary components influence composition, these microbial changes affect pathways, therapeutic implications modulating this axis for prevention management. Beneficial patterns, Mediterranean (MD) plant-based diets, promote diverse balanced supporting anti-inflammatory pathways. Conversely, Western (WD), high saturated fats refined sugars, associated with dysbiosis increased inflammation. With all links between three variables considered, attempts offer thorough examination triangle formed by food.

Language: Английский

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Gut microbiota as a key regulator of intestinal mucosal immunity

Life Sciences, Journal Year: 2024, Volume and Issue: 345, P. 122612 - 122612

Published: April 6, 2024

Language: Английский

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Critical Review of the Cross-Links Between Dietary Components, the Gut Microbiome, and Depression

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(2), P. 614 - 614

Published: Jan. 13, 2025

The complex relationship between diet, the gut microbiota, and mental health, particularly depression, has become a focal point of contemporary research. This critical review examines how specific dietary components, such as fiber, proteins, fats, vitamins, minerals, bioactive compounds, shape microbiome influence microbial metabolism in order to regulate depressive outcomes. These dietary-induced changes microbiota can modulate production metabolites, which play vital roles gut–brain communication. axis facilitates this communication through neural, immune, endocrine pathways. Alterations metabolites central nervous system (CNS) functions by impacting neuroplasticity, inflammatory responses, neurotransmitter levels—all are linked onset course depression. highlights recent findings linking components with beneficial composition reduced symptoms. We also explore challenges individual variability responses interventions long-term sustainability these strategies. underscores necessity for further longitudinal mechanistic studies elucidate precise mechanisms diet interactions be leveraged mitigate paving way personalized nutritional therapies.

Language: Английский

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Microbes Saving Lives and Reducing Suffering

Microbial Biotechnology, Journal Year: 2025, Volume and Issue: 18(1)

Published: Jan. 1, 2025

Language: Английский

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Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies

Reviews in Endocrine and Metabolic Disorders, Journal Year: 2023, Volume and Issue: 24(6), P. 1189 - 1204

Published: Oct. 16, 2023

Language: Английский

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Gut microbiota dysbiosis -associated obesity and its involvement in cardiovascular diseases and type 2 diabetes. A systematic review

Microvascular Research, Journal Year: 2023, Volume and Issue: 151, P. 104601 - 104601

Published: Sept. 9, 2023

Language: Английский

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Sleep Deprivation and Gut Microbiota Dysbiosis: Current Understandings and Implications

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(11), P. 9603 - 9603

Published: May 31, 2023

Gut microbiota comprises the microbial communities inhabiting our gastrointestinal (GI) tracts. Accordingly, these complex play a fundamental role in many host processes and are closely implicated human health diseases. Sleep deprivation (SD) has become increasingly common modern society, partly owing to rising pressure of work diversification entertainment. It is well documented that sleep loss significant cause various adverse outcomes on including immune-related metabolic Furthermore, accumulating evidence suggests gut dysbiosis associated with SD-induced In this review, we summarize caused by SD succedent diseases ranging from immune system organs highlight critical roles The implications possible strategies alleviate SD-related also provided.

Language: Английский

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