Characterization of Apis mellifera Gastrointestinal Microbiota and Lactic Acid Bacteria for Honeybee Protection—A Review

Cells, Journal Year: 2021, Volume and Issue: 10(3), P. 701 - 701

Published: March 22, 2021

Numerous honeybee (Apis mellifera) products, such as honey, propolis, and bee venom, are used in traditional medicine to prevent illness promote healing. Therefore, this insect has a huge impact on humans’ way of life the environment. While population A. mellifera is large, there concern that widespread commercialization beekeeping, combined with environmental pollution action pathogens, caused significant problems for health populations. One strategies preserve welfare honeybees better understand protect their natural microbiota. This paper provides unique overview latest research features functioning mellifera. Honeybee microbiome analysis focuses both function numerous factors affecting it. In addition, we present characteristics lactic acid bacteria (LAB) an important part gut community special beneficial activities health. The idea probiotics promising tool improve widely discussed. Knowledge microbiota opportunity create broad strategy vitality, including development modern probiotic preparations use instead conventional antibiotics, environmentally friendly biocides, biological control agents.

Language: Английский

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Probiotics as a biological detoxification tool of food chemical contamination: A review

Food and Chemical Toxicology, Journal Year: 2021, Volume and Issue: 153, P. 112306 - 112306

Published: May 28, 2021

Nowadays, people are exposed to diverse environmental and chemical pollutants produced by industry agriculture. Food contaminations such as persistent organic (POPs), heavy metals, mycotoxins a serious concern for global food safety with economic public health implications especially in the newly industrialized countries (NIC). Mounting evidence indicates that chronic exposure contaminants referred xenobiotics exert negative effect on human inflammation, oxidative stress, intestinal disorders linked perturbation of composition metabolic profile gut microflora. Although physicochemical technologies decontamination utilized many cases but require adequate conditions which often not feasible be met industrial sectors. At present, one promising approach reduce risk related presence foodstuffs is biological detoxification done probiotic strains their enzymes. Many studies confirmed probiotics an effective, feasible, inexpensive tool preventing xenobiotic-induced dysbiosis alleviating toxicity. This review aims summarize current knowledge direct mechanisms can influence xenobiotics. Moreover, probiotic-xenobiotic interactions microbiota host response were also discussed.

Language: Английский

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Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes

Nanomaterials, Journal Year: 2021, Volume and Issue: 11(8), P. 1968 - 1968

Published: July 30, 2021

Electrospinning is an inexpensive and powerful method that employs a polymer solution strong electric field to produce nanofibers. These can be applied in diverse biological medical applications. Due their large surface area, controllable functionalization properties, typically high biocompatibility electrospun nanofibers are recognized as promising materials for the manufacturing of drug delivery systems. offers potential formulate poorly soluble drugs amorphous solid dispersions improve solubility, bioavailability targeting release. It also successful strategy encapsulation nutraceuticals. This review aims briefly discuss concept electrospinning recent progress will further consider detail nutraceuticals, particularly probiotics.

Language: Английский

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The Gut-Brain Axis in Multiple Sclerosis. Is Its Dysfunction a Pathological Trigger or a Consequence of the Disease?

Frontiers in Immunology, Journal Year: 2021, Volume and Issue: 12

Published: Sept. 21, 2021

A large and expending body of evidence indicates that the gut-brain axis likely plays a crucial role in neurological diseases, including multiple sclerosis (MS). As whole, can be considered as bi-directional multi-crosstalk pathway governs interaction between gut microbiota organism. Perturbation commensal microbial population, referred to dysbiosis, is frequently associated with an increased intestinal permeability, or “leaky gut”, which allows entrance exogeneous molecules, particular bacterial products metabolites, disrupt tissue homeostasis induce inflammation, promoting both local systemic immune responses. An altered could therefore have significant repercussions not only on responses but also distal effector sites such CNS. Indeed, dysregulation this communication consequence dysbiosis has been implicated playing possible pathogenesis diseases. In (MS), increasingly being its pathogenesis, major focus specific alterations disease. MS purported murine model, experimental autoimmune encephalomyelitis (EAE), gastrointestinal symptoms and/or reported together permeability. EAE MS, components shown modulate regulatory T-cell disease progression, experiments germ-free pathogen-free mice transferred clearly demonstrated progression. Here, we review point two consequences dysfunction EAE: 1. pro-inflammatory environment “leaky” induced by lead CNS through cholinergic afferent fibers, thereby contributing inflammation pathogenesis; 2. Neuroinflammation affecting efferent transmission result progresses.

Language: Английский

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Nutritional and Health Potential of Probiotics: A Review

Applied Sciences, Journal Year: 2021, Volume and Issue: 11(23), P. 11204 - 11204

Published: Nov. 25, 2021

Several products consist of probiotics that are available in markets, and their potential uses growing day by day, mainly because some strains promote the health gut microbiota, especially Furmicutes Bacteroidetes, may prevent certain gastrointestinal tract (GIT) problems. Some common diseases inversely linked with consumption probiotics, i.e., obesity, type 2 diabetes, autism, osteoporosis, immunological disorders, for which disease progression gets delayed. In addition to mitigating properties, these microbes also improve oral, nutritional, intestinal health, followed a robust defensive mechanism against particular pathogens, specifically antimicrobial substances peptides producing (AMPs). All positive attributes depend upon microbial dispensed. Lactic acid bacteria (LAB) Bifidobacteria most used, but many other available, use depends origin health-promoting properties. This review article focuses on benefits, alleviating mechanisms chronic kidney (CKD), 1 diabetes (T1D), (T2D), gestational mellitus (GDM), obesity.

Language: Английский

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Consumer’s acceptability and health consciousness of probiotic and prebiotic of non-dairy products

Food Research International, Journal Year: 2021, Volume and Issue: 151, P. 110842 - 110842

Published: Dec. 3, 2021

Language: Английский

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Probiotics, Their Extracellular Vesicles and Infectious Diseases

Frontiers in Microbiology, Journal Year: 2022, Volume and Issue: 13

Published: March 30, 2022

Probiotics have been shown to be effective against infectious diseases in clinical trials, with either intestinal or extraintestinal health benefits. Even though probiotic effects are strain-specific, some "widespread effects" include: pathogen inhibition, enhancement of barrier integrity and regulation immune responses. The mechanisms involved the benefits probiotics not completely understood, but these can mediated, at least part, by probiotic-derived extracellular vesicles (EVs). However, date, there no trials examining EVs diseases. There is still a long way go bridge gap between basic research practice. This review attempts summarize current knowledge about released bacteria understand their possible role prevention and/or treatment A better understanding whereby package cargo process communication host cells (inter-kingdom communication), would allow further advances this field. In addition, we comment on potential use missing as therapeutic agents (postbiotics) Future needed open new avenues for encapsulation bioactives inside from GRAS (Generally Regarded Safe) bacteria. could scientific novelty applications functional foods pharmaceutical industries.

Language: Английский

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Probiotics and gut microbiota: mechanistic insights into gut immune homeostasis through TLR pathway regulation

Food & Function, Journal Year: 2022, Volume and Issue: 13(14), P. 7423 - 7447

Published: Jan. 1, 2022

Consumption of probiotics as a useful functional food improves the host's wellbeing, and, when paired with prebiotics (indigestible dietary fibre/carbohydrate), often benefits host through anaerobic fermentation.

Language: Английский

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Balancing reactive oxygen species generation by rebooting gut microbiota

Journal of Applied Microbiology, Journal Year: 2022, Volume and Issue: 132(6), P. 4112 - 4129

Published: Feb. 24, 2022

Reactive oxygen species (ROS; free radical form O2•- , superoxide radical; OH• hydroxyl ROO• peroxyl; RO• alkoxyl and non-radical 1 O2 singlet oxygen; H2 hydrogen peroxide) are inevitable companions of aerobic life with crucial role in gut health. But, overwhelming production ROS can cause serious damage to biomolecules. In this review, we have discussed several sources that be beneficial or dangerous the human gut. Micro-organisms, organelles enzymes play generation, where NOX1 is main intestinal enzyme, which produce intestine epithelial cells. Previous studies reported probiotics significant homeostasis by checking maintaining antioxidant level, immune system barrier protection. With current knowledge, critically analysed available literature presented outcome bubble maps suggest help controlling ROS-specific diseases, such as inflammatory bowel disease (IBD) colon cancer. Finally, it has been concluded rebooting microbiota probiotics, postbiotics faecal transplantation (FMT) implications structuring communities for personalized management gastrointestinal (GI) diseases.

Language: Английский

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Microbiome and Probiotics in Acne Vulgaris—A Narrative Review

Life, Journal Year: 2022, Volume and Issue: 12(3), P. 422 - 422

Published: March 15, 2022

Acne vulgaris is a chronic disease characterised by the appearance of eruptions such as whiteheads, blackheads, pustules, papules, and cysts. Among factors that cause acne are abnormal keratinisation sebaceous canal, bacterial colonisation (Cutibacterium acnes), increased sebum production, genotypic factors, hormonal disorders. Treatment often long tedious, can lead to reduction in quality life social isolation. The intestinal microbiota greatly important formation lesions. It also responsible for proper immunity organism. be related condition digestive tract its microbiome. Research shows use probiotics may reduce skin eruptions. probiotic supplementation cosmetics markets very dynamically developing. internal probiotic-containing gives hope improvement people with acne.

Language: Английский

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