3-(Propylthio)propane-1-sulfonic acid immobilized on functionalized magnetic nanoparticles as an efficient catalyst for one-pot synthesis of dihydrotetrazolo[1,5-a]pyrimidine and tetrahydrotetrazolo[5,1-b]quinazolinone derivatives DOI Creative Commons
Fatemeh Karimi,

Behnaz Tighsazzadeh,

Beheshteh Asadi

et al.

RSC Advances, Journal Year: 2022, Volume and Issue: 12(34), P. 22180 - 22187

Published: Jan. 1, 2022

An efficient and reusable catalyst, which is 3-(propylthio)propane-1-sulfonic acid immobillized on functionalized magnetic nanoparticles [PTPSA@SiO2-Fe3O4], has been synthesized. For the first time, it highlighted under solvent-free conditions for catalytic activity in multicomponent synthesis of dihydrotetrazolo[1,5-a]pyrimidines, dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylates tetrahydrotetrazolo[5,1-b]quinazolinones. The structure catalyst was well confirmed by characterization techniques, such as FT-IR, TGA, SEM-EDX, elemental mapping, TEM, VSM analysis. Besides, this unique found to be effectual up six cycles, made spotlighted. Recyclability excellent yield products, short reaction time clean profile are advantages present protocol.

Language: Английский

Magnetically recoverable catalysts for efficient multicomponent synthesis of organosulfur compounds DOI Creative Commons
Fadhil Faez Sead, Vicky Jain, Anjan Kumar

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(5), P. 3928 - 3953

Published: Jan. 1, 2025

This review studies magnetically recoverable catalysts designed for the efficient multicomponent synthesis of organosulfur compounds. These enhance process by combining efficiency with environmental sustainability.

Language: Английский

Citations

7
Rational Design of Covalent Organic Frameworks for Photocatalytic Hydrogen Peroxide Production DOI Open Access
Yang Ou, Yifan Zhang, Wen Luo

et al.

Macromolecular Rapid Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

Abstract Photocatalytic production of hydrogen peroxide (H 2 O ) represents a significant approach to achieving sustainable energy generation through solar energy, addressing both shortages and environmental pollution. Among various photocatalytic materials, covalent organic frameworks (COFs) have gained widespread attention in‐depth research due their unique advantages, including high porosity, predesignability, atomic‐level tunability. In recent years, progress has been made in the development, performance enhancement, mechanistic understanding COF‐based photocatalysts. This review focuses on latest advancements H using COFs, particularly emphasizing rational design COF structures regulate catalytic exploring fundamental processes involved photocatalysis. Based current achievements this field, paper also discusses existing challenges future opportunities, aiming provide reference for application COFs production.

Language: Английский

Citations

3
Deep Eutectic Solvents as Catalysts in the Synthesis of Active Pharmaceutical Ingredients and Precursors DOI Open Access

Chiara Falcini,

Gonzalo de Gonzalo

Catalysts, Journal Year: 2024, Volume and Issue: 14(2), P. 120 - 120

Published: Feb. 2, 2024

Deep Eutectic Solvents (DESs) have appeared in recent years as an appealing alternative to classical organic solvents, due their valuable environmental properties. In addition, these compounds, formed by the combination of one hydrogen bond donor with a acceptor at defined stoichiometric ratio, present other activities not only reaction medium. DESs can also be employed catalysts through hydrogen-bond interactions different chemical transformations, thus substituting hazardous reagents and solvents. The search for novel more environmentally friendly is area interest pharmaceutical chemists, therefore, efforts made application synthesis APIs or its precursors are described, focusing mainly on condensations, nucleophilic additions carbonyl moieties, multicomponent reactions.

Language: Английский

Citations

9
Ugi Four-Component Reactions Using Alternative Reactants DOI Creative Commons
Seyyed Emad Hooshmand, Wei Zhang

Molecules, Journal Year: 2023, Volume and Issue: 28(4), P. 1642 - 1642

Published: Feb. 8, 2023

The Ugi four-component reaction (Ugi-4CR) undoubtedly is the most prominent multicomponent (MCRs) that has sparked organic chemists’ interest in field. It been widely used synthesis of diverse heterocycle molecules such as potential drugs, natural product analogs, pseudo peptides, macrocycles, and functional materials. Ugi-4CRs involve use an amine, aldehyde or ketone, isocyanide, a carboxylic acid to produce α-acetamido carboxamide derivative, which significantly advanced field isocyanide-based MCRs. so-called intermediate nitrilium ion could be trapped by nucleophile azide, N-hydroxyphthalimide, thiol, saccharin, phenol, water, hydrogen sulfide instead original allow for wide variety Ugi-type reactions occur.β In addition there are alternative reagents other three components: ketone. All these components render aptly diversity-oriented myriad biologically active complex scaffolds. Consequently, this review will delve deeper into MCRs, particularly over past ten years.

Language: Английский

Citations

20
Advanced CuO-Ag2WO4-Ni nanophotocatalyst in the synthesis of some chromeno[4,3-b]chromenes as effective lung cancer drugs DOI
Sedighe Abbaspour, Rong Zhou,

Farokhzad M. Zonoz

et al.

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 170, P. 113284 - 113284

Published: Oct. 9, 2024

Language: Английский

Citations

6
One-pot synthesis of pyrimidinone and polyhydroquinoline derivatives with natural deep eutectic solvents (NADESs): Alternative to toxic organic solvents and environmental eco-friendly DOI Creative Commons

Sedigheh Ayazi Jannatabadi,

Rahman Hosseinzadeh, Behrooz Maleki

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: 12, P. 101848 - 101848

Published: Oct. 10, 2024

Language: Английский

Citations

6
Zinc Oxide Nanoparticles as Efficient Heterogeneous Catalyst for Synthesis of Bio‐active Heterocyclic Compounds DOI
Gourav Kumar, Vijesh Tomar, Parveen Kumar

et al.

ChemistrySelect, Journal Year: 2023, Volume and Issue: 8(41)

Published: Nov. 2, 2023

Abstract Among the most effective recoverable catalytic systems, metal‐oxide nanoparticles (NPs) are well known for their extensive uses in a broad range of industries, pharmaceuticals, and nano‐biotechnology. In addition, heterogeneous catalysis clearly defined materials which present an new possibilities research production innovative catalysts that help to solve world's energy environmental problems. ZnO‐NPs have been used as nanocatalysts according literature various kinds organic reactions. The advantages over bulk suggest this is promising field further research. This review article provides in‐depth overview several reported catalyse transformations including bio‐active compounds like benzofuran, coumarin, imidazole, indole, pyrazole, pyridine pyrimidine, thiazole, diazepine, azoles derivatives. Recent synthetic routes modifying functionalizing increase efficacy were also addressed, illustrated with schematics. development novel, highly effective, reusable modified catalysts, would clear way establishment greener sustainable technologies, key future catalysis. Researchers attempting synthesise functionalized will find informative.

Language: Английский

Citations

15
PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluo‐rescence Microscopy DOI Creative Commons
Iakovos Saridakis, Margaux Riomet, Oliver John V. Belleza

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(19)

Published: April 3, 2024

Abstract The deployment of small‐molecule fluorescent agents plays an ever‐growing role in medicine and drug development. Herein, we complement the portfolio powerful fluorophores, reporting serendipitous discovery development a novel class with imidazo[1,2‐a]pyridinium triflate core, which term PyrAtes . These fluorophores are synthesized single step from readily available materials (>60 examples) display Stokes shifts as large 240 nm, while also reaching NIR−I emissions at λ max long 720 nm. Computational studies allow platform for prediction Em Furthermore, demonstrate compatibility these live cell imaging HEK293 cells, suggesting potent intracellular markers.

Language: Английский

Citations

5
Catalytic Stereoselective Multicomponent Reactions for the Synthesis of Spiro Derivatives: Recent Progress DOI

Divyang M. Patel,

Paras J. Patel,

Hitendra M. Patel

et al.

European Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 2022(46)

Published: Nov. 16, 2022

Abstract Spiro derivatives are important scaffolding substances found in many natural products and pharmaceuticals. In the last decade, numerous new approaches based on multicomponent reactions have been explored for selective efficient development of spiro using various organocatalytic transition metal‐based catalytic systems. This Review discusses pioneering advances field stereoselective preparation derivatives. These include Michael cascade cyclization reactions, cycloadditions, diastereoselective miscellaneous synthesis spiro‐hetero/carbocycles. Advances decade made it possible to synthesize compounds with good excellent stereoselectivity under appropriate reaction conditions. However, achieving high regioselectivity several described remains a challenge. Organocatalysts transition‐metal‐based catalysts play crucial role this milestone. Proposed mechanisms supporting evidence highlighted Review. The progress is immense. expected that synthetic methods will soon be developed can widely used spiro‐heterocycles/carbocycles.

Language: Английский

Citations

20
Immobilized nickel boride nanoparticles on magnetic functionalized multi-walled carbon nanotubes: a new nanocomposite for the efficient one-pot synthesis of 1,4-benzodiazepines DOI Creative Commons

Farkhondeh Mohammad Aminzadeh,

Behzad Zeynizadeh

Nanoscale Advances, Journal Year: 2023, Volume and Issue: 5(17), P. 4499 - 4520

Published: Jan. 1, 2023

In this study, a new magnetic nanocomposite consisting of Ni2B nanoparticles anchored on functionalized multi-walled carbon nanotubes (Fe3O4/f-MWCNT/Ni2B) was synthesized and characterized using various techniques such as FT-IR, XRD, FESEM, SEM-based EDX, elemental mapping, HRTEM, DLS, SAED, XPS, BET, TGA, VSM. The as-prepared successfully employed for the preparation bioactive 1,4-benzodiazepines from three-component reaction o-phenylenediamine (1), dimedone (2), different aldehydes (3), in polyethylene glycol 400 (PEG-400) solvent at 60 °C. obtained results demonstrated that current one-pot protocol offers many advantages, good-to-excellent yields within acceptable times, favorable TONs TOFs, eco-friendliness procedure, easy nanocomposite, mild conditions, broad range products, excellent catalytic activity, green solvent, reusability nanocomposite.

Language: Английский

Citations

11