The interplay between diet and the gut microbiome: implications for health and disease

Nature Reviews Microbiology, Journal Year: 2024, Volume and Issue: 22(11), P. 671 - 686

Published: July 15, 2024

Language: Английский

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Approach to the diagnosis and management of dysbiosis

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: April 19, 2024

All microorganisms like bacteria, viruses and fungi that reside within a host environment are considered microbiome. The number of bacteria almost equal human cells, however, the genome these may be 100 times larger than genome. Every aspect physiology health can influenced by microbiome living in various parts our body. Any imbalance composition or function is seen as dysbiosis. Different types dysbiosis corresponding symptoms depend on site microbial imbalance. contribution intestinal extra-intestinal microbiota to influence systemic activities through interplay between different axes. Whole body complex process involving gut non-gut related It still at stage infancy has not yet been fully understood. Dysbiosis genetic factors, lifestyle habits, diet including ultra-processed foods food additives, well medications. associated with many diseases cannot diagnosed standard blood tests investigations. Microbiota derived metabolites analyzed useful management addressed altering proper modulation. effect interventions humans depends beneficial alteration mostly based animal studies evolving evidence from studies. There tremendous potential for diagnosis, treatment, prognosis diseases, as, monitoring disease humans. system-based approach diagnosis better pure taxonomic approach. could new therapeutic target conditions.

Language: Английский

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Dietary additives interloping with the epigenetic network and human health: implications in gut microbiota and endocrine toxicity

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 105903 - 105903

Published: Jan. 1, 2025

Language: Английский

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The food additive butylated hydroxyanisole minimally affects the human gut microbiome ex vivo

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 143037 - 143037

Published: Jan. 1, 2025

Language: Английский

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Alterations in gut microbiome and metabolite profiling during in vitro fermentation of duckweed (Wolffia globosa) and its extracts by gut bacteria from obese adults

Future Foods, Journal Year: 2025, Volume and Issue: unknown, P. 100608 - 100608

Published: March 1, 2025

Language: Английский

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Vitamin K2 in Health and Disease: A Clinical Perspective

Foods, Journal Year: 2024, Volume and Issue: 13(11), P. 1646 - 1646

Published: May 24, 2024

Vitamins are essential organic compounds that vary widely in chemical structure and vital small quantities for numerous biochemical biological functions. They critical metabolism, growth, development maintaining overall health. categorised into two groups: hydrophilic lipophilic. Vitamin K (VK), a lipophilic vitamin, occurs naturally primary forms: phylloquinone (VK1), found green leafy vegetables algae, Menaquinones (VK2), present certain fermented animal foods formulated VK supplements. This review explores the possible factors contributing to deficiency, including dietary influences, discusses pharmacological therapeutic potential of supplementary VK2, examining recent global clinical studies on its role treating diseases such as osteoporosis, osteoarthritis, rheumatoid arthritis, cardiovascular disease, chronic kidney diabetes, neurodegenerative disorders cancers. The analysis includes published articles from multiple databases, Scopus, PubMed, Google Scholar, ISI Web Science CNKI, focusing human studies. findings indicate VK2 is versatile vitamin health broadly positive correlation exists between supplementation improved outcomes. However, data somewhat inconsistent, highlighting need further detailed research VK2's metabolic processes, biomarker validation, dose-response relationships, bioavailability safety. Establishing Recommended Daily Intake could significantly enhance

Language: Английский

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Nutritional Biomarkers for the Prediction of Response to Anti-TNF-α Therapy in Crohn’s Disease: New Tools for New Approaches

Nutrients, Journal Year: 2024, Volume and Issue: 16(2), P. 280 - 280

Published: Jan. 17, 2024

Crohn's disease (CD) is a chronic disorder of the digestive tract characterized by an uncontrolled immune-mediated inflammatory response in genetically predisposed individuals exposed to environmental risk factors. Although diet has been identified as one major factors, role nutrients clinical management CD patients not yet fully investigated. In this prospective observational study, fifty-four diagnosed with active and undergoing anti-TNF-α biological therapy were enrolled subjected nutrient intake analysis through daily food diary. Their blood values analyzed before after 6 months therapy. After anti-TNF-α, four dropped out leaving 29 remission 21 still that remained same. The aim study was identify whose or may be associated patients' responses diet, remaining showed very similar dietary compared achieving except for trend lower starting zinc intake, below reference value. blood, instead, who did respond significantly plasma iron taurine treatment.

Language: Английский

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Sunset Yellow dye effects on gut microbiota, intestinal integrity, and the induction of inflammasomopathy with pyroptotic signaling in male Wistar rats

Food and Chemical Toxicology, Journal Year: 2024, Volume and Issue: 187, P. 114585 - 114585

Published: March 13, 2024

Language: Английский

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Artemisia spp. Essential Oils: From Their Ethnobotanical Use to Unraveling the Microbiota Modulation Potential

Plants, Journal Year: 2024, Volume and Issue: 13(7), P. 967 - 967

Published: March 27, 2024

Background. The 2015 Nobel Prize in Medicine, awarded for the discovery of artemisinin Artemisia annua, reignited interest aromatic plants, including absinthium L. This article delves into historical, ethnopharmacological and medicinal significance A. absinthium, examining its bitter taste noted since ancient Greek times association with properties throughout history. Despite being banned 20th century due to perceived health risks; recent research has led reconsideration absinthium’s potential applications. study focuses on prebiotic efficacy essential oils (EOs) from two species: annua. Materials methods. A broth microdilution test, growth curve test vivo models were used impact low doses (from 0.5% v/v 0.00048 v/v) spp-EO three probiotic strains (Lactobacillus, Lactobacillus casei Saccharomyces boulardii). Results. These oils, when minimal concentrations (lower than 0.06% v/v), are safe exhibit effects major strains, supporting traditional culinary use spp. Conclusion. opens avenues applications food industry, emphasizing need further exploration spp-EOs their influence microbiota.

Language: Английский

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Ultra-Processed Foods Consumption and Asthma in the Western Diet

Dietetics, Journal Year: 2024, Volume and Issue: 3(2), P. 144 - 158

Published: May 7, 2024

Obesity is considered an important risk factor for the onset of asthma, playing a key role in enhancing disease’s severity. However, there increasing evidence linking not only obesity but also overweight with higher asthma. Although correlation between and asthma has already been reported, several aspects are still fully elucidated, mainly about inflammatory processes underlying both diseases. It well known that Western-type calorically rich diets overfeeding can act as triggers chronic metabolic inflammation, few studies have examined associations ultra-processed foods (UPFs) intake, despite its positive obesity, biomarkers inflammation. In addition to their nutrient composition, UPF may chemical additives contaminants from packaging, whose effects on health food addiction under research. this review, we provide overview current data identify obese phenotype consumption, highlighting potential central played by intestinal microbiota.

Language: Английский

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