Bovine Colostrum in Pediatric Nutrition and Health DOI Open Access

Ahmet Alperen Canbolat,

Mauro Lombardo, Alicia del Carmen Mondragón

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(24), P. 4305 - 4305

Published: Dec. 13, 2024

Bovine colostrum (BC), the first milk secreted by mammals after birth, is a trending alternative source for supplementing infants and children, offering benefits gut immune health. Its rich components, such as proteins, immunoglobulins, lactoferrin, glycans, are used to fortify diets support development. Preterm development crucial, especially in maturation of essential systems, from 2010 2020, approximately 15% all premature births occurred at less than 32 weeks gestation worldwide. This review explores composition, benefits, effects BC on general along with preterm who require special care, highlights its role growth also associated specific pediatric diseases, including necrotizing enterocolitis (NEC), infectious diarrhea, inflammatory bowel disease (IBD), short-bowel syndrome (SBS), neonatal sepsis, gastrointestinal respiratory infections, some minor conditions. discusses clinical trials regarding these conditions which occasionally encountered infants. The anti-inflammatory, antimicrobial, immunomodulatory, antiviral properties discussed, emphasizing mechanisms action. Clinical trials, particularly humans, provide evidence supporting inclusion formulas diets, although precise standards age, feeding time, amounts needed ensure safety efficacy. However, potential adverse effects, allergic reactions caseins immunoglobulin E, must be considered. More comprehensive necessary expand infant feeding, important components BC, should further studied their synergistic diseases. Ultimately, shows promise health incorporated into nutritional supplements caution.

Language: Английский

Functional Yogurt: Types and Health Benefits DOI Creative Commons
Sümeyye Sarıtaş, Alicia del Carmen Mondragón, José Manuel Miranda

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(24), P. 11798 - 11798

Published: Dec. 17, 2024

In the past decade, increasing interest in healthy consumption has encouraged development of functional products yogurt sector. Dairy are extensively used production foods because their excellent and versatile technological properties. Among dairy products, is one that been most widely to deliver bioactive compounds consumers. The market features various types yogurt, including probiotic, prebiotic, synbiotic, high protein, lactose free, novel known as easy-to-digest yogurt. added ingredients these influence structural, nutritional, properties These effects vary depending on chemical biological characteristics each ingredient. Additionally, during fermentation, substances can impact number viability bacteria involved, affecting quality storage. Furthermore, associated with health benefits. benefits linked not only supporting but also altering course a disease or alleviating symptoms. This review article discusses its effects, incorporating recent studies.

Language: Английский

Citations

5

Mechanisms and Potential Benefits of Neuroprotective Agents in Neurological Health DOI Open Access
Burcu Pekdemir, António Raposo, Ariana Saraiva

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(24), P. 4368 - 4368

Published: Dec. 18, 2024

The brain contains many interconnected and complex cellular molecular mechanisms. Injury to the causes permanent dysfunctions in these So, it continues be an area where surgical intervention cannot performed except for removal of tumors repair some aneurysms. Some agents that can cross blood–brain barrier reach neurons show neuroprotective effects due their anti-apoptotic, anti-inflammatory antioxidant properties. In particular, act by reducing or modulating accumulation protein aggregates neurodegenerative diseases (Alzheimer’s disease, Parkinson’s Huntington’s Amyotrophic lateral sclerosis, prion disease) caused accumulation. Substrate increased oxidative stress stimulates brain’s immune cells, microglia, astrocytes, secrete proinflammatory cytokines. Long-term chronic neuroinflammatory response triggers apoptosis. Brain damage is observed with neuronal apoptosis functions are impaired. This situation negatively affects processes such as motor movements, memory, perception, learning. Neuroprotective prevent molecules play a role addition, they improve impaired supporting neuroplasticity neurogenesis. Due important roles central nervous system diseases, elucidate review provides overview mechanisms flavonoids, which constitute large part effects, well vitamins, neurotransmitters, hormones, amino acids, derivatives. It thought understanding will enable development new therapeutic different treatment strategies.

Language: Английский

Citations

5

The Impact of Freeze Drying on Bioactivity and Physical Properties of Food Products DOI Creative Commons

Nurten Coşkun,

Sümeyye Sarıtaş, Yassine Jaouhari

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(20), P. 9183 - 9183

Published: Oct. 10, 2024

Freeze drying (FD) is a technique used to preserve the bioactive content and flavor of samples. Foods with short shelf life due nature have been preserved via FD in recent years. The success thanks high retention ability compounds sample. However, cost energy consumption limit its usage several fields. Freezing, primary drying, secondary which take place same device, are stages FD. In addition, parameters, including pretreatment, size, temperature, sample species, time, pressure, affect process. These parameters controlled increase effectiveness on Moreover, has compared other techniques hot air microwave vacuum solar determine protective capability. It also applied valorization waste products, common problem worldwide. For valorization, microencapsulation powder production achieved using years, studies effects use various materials increased, providing new aspects for future science food industry.

Language: Английский

Citations

5

Lactoferrin: A Promising Therapeutic Molecule against Human Papillomavirus DOI Open Access
Merve Kaplan, Merve Baktıroğlu, Arda Erkan Kalkan

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(18), P. 3073 - 3073

Published: Sept. 12, 2024

Lactoferrin is a multifunctional glycoprotein naturally found in mammalian secretions, predominantly colostrum and milk. As key component of dairy foods, lactoferrin enhances viral protection boosts human health, owing to its fundamental properties including antiviral, anti-inflammatory, immune-modulatory effects. Importantly, the antiviral effect has been shown against range viruses causing serious infections threatening health. One that exerts significant effects on papillomavirus (HPV), which most prevalent transmitted infection affecting myriad people around world. high potential inhibit HPV via different mechanisms, direct binding envelope proteins or their cell receptors, thereby hindering entry immune stimulation by triggering release some immune-related molecules through body, such as lymphocytes. Along with HPV, also can coronaviruses hepatitis same manner. Here, we overview current knowledge other infections.

Language: Английский

Citations

4

The Potential Applications of Natural Colostrum in Skin Health DOI Creative Commons
Ecem Bolat, Zeynep Karagöz, José Luiz de Brito Alves

et al.

Cosmetics, Journal Year: 2024, Volume and Issue: 11(6), P. 197 - 197

Published: Nov. 20, 2024

Skin is a crucial organ for preserving the body’s equilibrium. Like other parts of body, skin also ages due to extrinsic and intrinsic factors, leading several signs such as wrinkles, spots, decline in elasticity, causing range issues similar those seen elsewhere body. Some these factors include ultraviolet (UV) radiation, hormonal disorders, genetic loss moisture, metabolic exposure chemicals, smoking. Colostrum, which initial foremilk, has shown positive effects on consequences factors. Its content richer than mature milk contains beneficial components. For instance, it includes hyaluronic acid, molecule that binds water keeps hydrated; lactoferrin, with high antimicrobial properties; immunoglobulins, are responsible immunity; growth increase amount collagen, main protein type skin; and, finally, telomerase enzyme, maintains telomere’s length thus, decelerates aging process. It recently become apparent using products natural ingredients essential. Considering its nature, contents, effects, colostrum stands out an excellent material cosmetic industry, especially sector. Therefore, aim this review article demonstrate potential application health usage

Language: Английский

Citations

4

Lactoferrin: Properties and Potential Uses in the Food Industry DOI Open Access
Ramazan Demir, Sümeyye Sarıtaş, Mikhaël Bechelany

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1404 - 1404

Published: Feb. 7, 2025

Lactoferrin (LF) is an 80 kDa glycoprotein that contains approximately 700 amino acids and a member of the transferrin family. The essential properties LF, including antimicrobial, antiviral, anticancer, anti-inflammatory, antioxidant, probiotic effects, have been studied for decades. iron chelation activity LF significantly associated with its antioxidant properties. Owing to prebiotic activity, also facilitates growth beneficial microorganisms iron-defense immediate-effect on pathogens. Additionally, ability regulate cell signaling pathways immune responses makes prominent modulatory protein. These diverse characteristics gained interest in therapeutic potential. Studies suggested could serve as alternative source antibiotics severe infections illnesses. has food industry potential additive fortify products such yogurt, infant formula, meat derivatives while improving shelf life foods providing antimicrobial activity. Prior using industry, safety toxicity processing are necessary be investigated. investigations crucial addressing harm or side effects ensuring healthy lifestyle. This review discusses attributes particularly exploitation industry.

Language: Английский

Citations

0

Advancing Pickling Techniques to Enhance Bioactive Compounds and Probiotic Content in Pickled Vegetables DOI
Ahmada Ahmada Kh, Abdullah Abdulaziz Abbod Abdo, Sohail Khan

et al.

Food Reviews International, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 27

Published: March 12, 2025

Language: Английский

Citations

0

Enhancing the Physicochemical Properties, Bioactivity, and Functional Applications of Fresh Jujube Juice Using Media Milling DOI Creative Commons
Hong‐Yi Kang,

An‐I Yeh,

Min‐Hsiung Pan

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

This study systematically evaluated the effects of media milling on physicochemical properties, bioactive compound content, and functional applications fresh jujube (Ziziphus jujuba Mill.) juice. Optimization experiments identified ideal conditions for nanoparticle production, including 5% solid content a 180 min duration, resulting in significantly reduced particle sizes─volume-weighted average diameter (from 229.0 ± 1.0 to 25.0 0.2 μm) number-weighted 7.2 0.0 0.1 μm)─and improved dispersion stability. Media enhanced key properties such as zeta potential, viscosity, suspension stability, while also modifying color pH. The process notably increased compounds, total flavonoids 2.9 3.8 mg catechin equivalent (CE)/g dry weight (DW)) triterpenoids 15.4 1.2 28.0 4.9 oleanolic acid (OAE)/g DW). antioxidant activity before after milling, assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing power (FRAP), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays, remained comparable. Fermentation with Lactiplantibacillus plantarum demonstrated that both blended media-milled juice can serve effective substrates substrate utilization lactic production. Anti-inflammatory assays RAW 264.7 macrophages revealed nitric oxide production lower levels pro-inflammatory cytokines IL-1β, showcasing juice's potential modulate inflammation. In dextran sodium sulfate (DSS)-induced colitis mouse model, safety, though it did not show significant protective effects. These findings position promising food ingredient health promotion disease management.

Language: Английский

Citations

0

Exploring the Microbiome and Functional Metabolism of Fermented Camel Milk (Shubat) Using Metagenomics DOI Creative Commons
Sagyman Zhadyra, Fei Tao, Ping Xu

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(7), P. 1102 - 1102

Published: March 22, 2025

Shubat is a traditional fermented camel milk drink that originated in Central Asia, with especially deep cultural roots Kazakhstan. However, systematic studies on the microbial ecology and functional genes of remain scarce. As distinctive fer-mented food, its diversity properties have not been fully ex-plored. This study investigates potential by using advanced metagenomic techniques. Its community mainly composed bacteria (96.6%), Lactobacillus, Lactococcus, Streptococcus being dominant genera. Functional annotations through EggNOG, KEGG, CAZy databases highlighted metabolic versatility Shubat's microbiota. Key pathways included amino acid carbohydrate metabolism, vitamin biosynthesis, central carbon emphasizing their roles fermentation nutritional enhancement. The identification various enzymes related to chemical synthesis further emphasizes contribution microbiota unique flavor texture. only provides an important basis for scientific understanding but also expands application possibilities food field health nutrition confers modern value significance food. integration science tradition has facilitated development microbiology paved new global dissemination foods foods.

Language: Английский

Citations

0

Enhancing total phenolic, flavonoid, and antioxidant capacity in black orchid (Coelogyne pandurata Lindl.) with paclobutrazol application DOI Creative Commons
Pebra Heriansyah, Sandra Arifin Aziz, Dewi Sukma

et al.

BIO Web of Conferences, Journal Year: 2025, Volume and Issue: 171, P. 01007 - 01007

Published: Jan. 1, 2025

The Black Orchid ( Coelogyne pandurata Lindl.) is a species with promising secondary metabolite content, including total phenolics, flavonoids, and antioxidant capacity, making it highly valuable for horticultural applications. This research investigated the influence of Paclobutrazol application on phenolic flavonoid capacity Orchid. study was conducted using randomized complete block design (RCBD) treatments at concentrations 0, 50, 100, 150 ppm. Each experimental unit three replicates. data were analyzed ANOVA, followed by Tukey’s HSD test 5% significance level to compare treatment means. Total phenolic, flavonoid, capacities analysed Nano-spectrophotometer. Results indicated that ppm significantly increased concentration in leaves, showing significant difference compared control. However, no effect observed content or activity either leaves bulbs.

Language: Английский

Citations

0