Magnetochemistry,
Journal Year:
2022,
Volume and Issue:
9(1), P. 12 - 12
Published: Dec. 30, 2022
Magnetic
nanocomposites
(MNCs)
combine
the
features
of
magnetic
nanoparticles
and
a
second
material,
which
provide
distinct
physical,
chemical,
biological
properties.
The
core
for
nanocomposite
synthesis
is
extensively
used
due
to
its
high
saturation
magnetization,
chemical
stability,
large
surface
area,
easy
functionalization.
Moreover,
(MNPs)
have
great
potential
resonance
imaging
(MRI),
particle
(MPI),
hyperthermia,
targeted
drug
gene
delivery
by
an
external
field.
Numerous
composing
units
exist,
leads
outstanding
application
composites.
This
review
focuses
on
nucleic
acid-based
bioapplications
MNCs
with
polymeric,
organic,
inorganic,
biomolecules,
bioinspared
coating.
In
addition,
different
forms,
such
as
core–shell,
doping,
multilayer,
yolk–shell,
Janus-shaped
hybrids,
are
discussed,
their
unique
properties
highlighted.
types
molecularly
imprinted
polymer
(MMIP)
presented.
presents
only
using
ready-made
cores.
These
restrictions
associated
many
materials,
quantitative
qualitative
composition,
procedures.
aims
discuss
MNC
information
available
researchers
in
this
field
guide
them
through
some
problems
structure
variation,
functionalization
possibilities.
most
recent
advancements
polymers
therapy,
diagnostics,
theranostics,
separation,
biocatalytic,
biosensing
introduced.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(3), P. 868 - 868
Published: March 7, 2023
The
new
era
of
nanomedicine
offers
significant
opportunities
for
cancer
diagnostics
and
treatment.
Magnetic
nanoplatforms
could
be
highly
effective
tools
diagnosis
treatment
in
the
future.
Due
to
their
tunable
morphologies
superior
properties,
multifunctional
magnetic
nanomaterials
hybrid
nanostructures
can
designed
as
specific
carriers
drugs,
imaging
agents,
theranostics.
Multifunctional
are
promising
theranostic
agents
due
ability
diagnose
combine
therapies.
This
review
provides
a
comprehensive
overview
development
advanced
combining
optical
providing
photoresponsive
platforms
medical
applications.
Moreover,
this
discusses
various
innovative
developments
using
nanostructures,
including
drug
delivery,
treatment,
tumor-specific
ligands
that
deliver
chemotherapeutics
or
hormonal
resonance
imaging,
tissue
engineering.
Additionally,
artificial
intelligence
(AI)
used
optimize
material
properties
based
on
predicted
interactions
with
cell
membranes,
vasculature,
biological
fluid,
immune
system
enhance
effectiveness
therapeutic
agents.
Furthermore,
an
AI
approaches
assess
practical
utility
Finally,
presents
current
knowledge
perspectives
systems
models.
International Journal of Thermofluids,
Journal Year:
2024,
Volume and Issue:
22, P. 100705 - 100705
Published: May 1, 2024
Nanofluids,
comprising
nanoparticles
and
a
base
fluid,
have
captured
substantial
interest
due
to
remarkable
enhancements
in
thermal
conductivity
other
crucial
thermophysical
properties.
These
advancements
facilitate
diverse
applications
across
various
industrial
processes,
including
biomedical
drug
research.
This
review
centers
on
non-Newtonian
nanofluids,
which
diverge
from
Newton's
law
of
viscosity,
rendering
them
more
adaptable
versatile.
Through
comprehensive
examination
the
latest
research,
preparation
methods,
both
one-step
two-step
techniques,
their
formulations
oil-based,
water-based,
ethylene
glycol-based
solutions
are
systematically
explored.
The
study
synthesizes
findings
that
highlight
significant
improvements
heat
transfer
efficiency
introduces
novel
sectors,
such
as
engineering
energy
systems.
Furthermore,
an
in-depth
characterization
nanofluids
is
provided,
covering
rheological,
dispersion,
transport,
magnetic,
optical,
radiative
fluids
increasingly
utilized
exchangers,
automotive
radiators,
engines,
solar
collectors,
electronic
coolants,
demonstrating
broad
spectrum
practical
applications.
shows
ongoing
challenges
primarily
centered
preparation,
stability,
commercialization
nanofluids.
Conclusively,
paper
underscores
potential
revolutionize
technological
areas
advocates
for
continued
research
develop
stable
efficient
formulations,
paving
way
innovative
scientific
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 2529 - 2552
Published: March 1, 2024
Abstract:
The
blood-brain
barrier
(BBB)
and
blood-tumor
(BTB)
pose
substantial
challenges
to
efficacious
drug
delivery
for
glioblastoma
multiforme
(GBM),
a
primary
brain
tumor
with
poor
prognosis.
Nanoparticle-based
combinational
strategies
have
emerged
as
promising
modalities
overcome
these
barriers
enhance
penetration
into
the
parenchyma.
This
review
discusses
various
nanoparticle-based
combinatorial
approaches
that
combine
nanoparticles
cell-based
delivery,
viral
focused
ultrasound,
magnetic
field,
intranasal
permeability
across
BBB
BTB.
Cell-based
involves
using
engineered
cells
carriers
nanoparticles,
taking
advantage
of
their
intrinsic
migratory
homing
capabilities
facilitate
transport
therapeutic
payloads
Viral
uses
vectors
deliver
genes
or
specific
within
GBM
microenvironment.
Focused
coupled
microbubbles
can
temporarily
disrupt
increase
permeability.
Magnetic
field-guided
exploits
targeted
under
an
external
field.
Intranasal
offers
minimally
invasive
avenue
bypass
agents
directly
via
olfactory
trigeminal
pathways.
By
combining
strategies,
synergistic
effects
efficiency,
improve
efficacy,
reduce
off-target
effects.
Future
research
should
focus
on
optimizing
nanoparticle
design,
exploring
new
combination
advancing
preclinical
clinical
investigations
promote
translation
therapies
GBM.
Keywords:
glioblastoma,
barrier,
nanoparticle,
strategy,
ultrasound-wave,
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(11), P. 2388 - 2388
Published: Nov. 5, 2022
Cancer
immunotherapy
has
tremendous
promise,
but
it
yet
to
be
clinically
applied
in
a
wider
variety
of
tumor
situations.
Many
therapeutic
combinations
are
envisaged
improve
their
effectiveness.
In
this
way,
strategies
capable
inducing
immunogenic
cell
death
(e.g.,
doxorubicin,
radiotherapy,
hyperthermia)
and
the
reprogramming
immunosuppressive
microenvironment
(TME)
M2-to-M1-like
macrophages
repolarization
tumor-associated
(TAMs))
particularly
appealing
enhance
efficacy
approved
immunotherapies
immune
checkpoint
inhibitors,
ICIs).
Due
modular
construction
versatility,
iron
oxide-based
nanomedicines
such
as
superparamagnetic
oxide
nanoparticles
(SPIONs)
can
combine
these
different
approaches
single
agent.
SPIONs
have
already
shown
safety
biocompatibility
possess
both
drug-delivery
chemotherapy,
ICIs)
magnetic
capabilities
hyperthermia
(MHT),
resonance
imaging).
review,
we
will
discuss
multiple
applications
cancer
immunotherapy,
focusing
on
theranostic
properties
target
TAMs
generate
MHT.
The
first
section
review
briefly
describe
targets
for
NPs.
following
sections
deal
with
overall
(including
MHT).
last
is
dedicated
SPION-induced
response
through
its
effects
