Responsive silver orthophosphate nanoparticles for antibacterial and antibiofilm activity against uropathogens DOI

Swarnaprabha Pany,

Ram Prasad Sahu,

Manoranjan Ranjit‬

et al.

Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications DOI Creative Commons
Emir Akdaşçi, Hatice Duman, Furkan Eker

et al.

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(2), P. 126 - 126

Published: Jan. 16, 2025

Chitosan, a multifaceted amino polysaccharide biopolymer derived from chitin, has extensive antibacterial efficacy against diverse pathogenic microorganisms, including both Gram-negative and Gram-positive bacteria, in addition to fungi. Over the course of last several decades, chitosan nanoparticles (NPs), which are polymeric bio-based, have garnered great deal interest as efficient agents. This is mostly due fact that they used wide variety applications, medical treatments, food, chemicals, agricultural products. Within context mechanism NPs, we present review provides an overview synthesis methods, novel procedures, compiles applications been developed field biomedicine. These include wound healing, drug delivery, dental treatment, water purification, agriculture, food preservation. In this, focus on mechanisms action factors determine activity its derivatives. conjunction with this line inquiry, researchers strongly urged concentrate their efforts developing ground-breaking NPs.

Language: Английский

Citations

6

Silver Nanoparticles (AgNPs): Comprehensive Insights into Bio/Synthesis, Key Influencing Factors, Multifaceted Applications, and Toxicity─A 2024 Update DOI Creative Commons

Abhinav Sati,

Tanvi N. Ranade,

Suraj N. Mali

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Silver nanoparticles (AgNPs) are widely recognized for their unique optical, electronic, and antibacterial properties, enabling use in biosensing, photonics, electronics, drug delivery, antimicrobial treatments. Green chemistry-based biological synthesis methods offer an eco-friendly alternative to traditional chemical techniques. Among metallic (NPs) metal oxides, those derived from plant extracts exhibit notable medicinal properties. Due exceptional stability low reactivity, AgNPs particularly well-suited various applications. can be synthesized through chemical, physical, or methods, each with distinct benefits challenges. Chemical physical approaches often involve complex purification, reactive reagents, high energy demands, while though slower, provide sustainable solutions. The chosen method strongly influences the stability, size, purity of resulting NPs. This review emphasizes importance selecting appropriate optimize characteristics functionality silver It consolidates research spanning past two decades, including most recent findings 2024. A comprehensive electronic search databases such as PubMed, Scopus, ScienceDirect, Cochrane, Google Scholar was conducted up-to-date overview advances applications nanoparticles.

Language: Английский

Citations

5

Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects DOI Creative Commons
Hatice Duman, Emir Akdaşçi, Furkan Eker

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(22), P. 1805 - 1805

Published: Nov. 11, 2024

Gold nanoparticles (NPs) are among the most commonly employed metal NPs in biological applications, with distinctive physicochemical features. Their extraordinary optical properties, stemming from strong localized surface plasmon resonance (LSPR), contribute to development of novel approaches areas bioimaging, biosensing, and cancer research, especially for photothermal photodynamic therapy. The ease functionalization various ligands provides a approach precise delivery these molecules targeted areas. NPs' ability transfer heat electricity positions them as valuable materials advancing thermal management electronic systems. Moreover, their inherent characteristics, such inertness, give rise synthesis antibacterial antioxidant agents they provide biocompatible low-toxicity approach. Chemical physical methods utilized produce gold NPs. pursuit more ecologically sustainable economically viable large-scale technologies, environmentally benign processes referred green/biological synthesis, has garnered increasing interest global researchers. Green favorable than other techniques minimize necessity hazardous chemicals reduction process due simplicity, cost-effectiveness, energy efficiency, biocompatibility. This article discusses importance NPs, optical, conductivity, antibacterial, antioxidant, anticancer methods, contemporary uses, biosafety, emphasizing need understand toxicology principles green commercialization strategies.

Language: Английский

Citations

6

Gold Nanoparticles in Nanomedicine: Unique Properties and Therapeutic Potential DOI Creative Commons
Furkan Eker, Emir Akdaşçi, Hatice Duman

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(22), P. 1854 - 1854

Published: Nov. 20, 2024

Gold nanoparticles (NPs) have demonstrated significance in several important fields, including drug delivery and anticancer research, due to their unique properties. NPs possess significant optical characteristics that enhance application biosensor development for diagnosis, photothermal photodynamic therapies treatment, targeted bioimaging. The broad surface modification possibilities of gold been utilized the various molecules, nucleic acids, drugs, proteins. Moreover, strong localized plasmon resonance (LSPR) properties, facilitating use surface-enhanced Raman scattering precise efficient biomolecule detection. These properties are extensively research. Both show results treatments using NPs. Additionally, demonstrate potential other biological areas, particularly antimicrobial activity. In addition delivering antigens, peptides, antibiotics activity, can penetrate cell membranes induce apoptosis through intracellular mechanisms. Among types metal NPs, more tolerable toxicity capacity, supporting wide-ranging areas. hold a special position nanomaterial offering limited This review aims address recently highlighted applications current status NP research discuss future nanomedicine.

Language: Английский

Citations

4

Green Biosynthesis of Nanoparticles Using Plant Extracts: Mechanisms, Advances, Challenges, and Applications DOI
Great Iruoghene Edo, Alice Njolke Mafe,

Ali B. M. Ali

et al.

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)

Published: March 13, 2025

Language: Английский

Citations

0

Bioactive Hybrid Hydrogels Reinforced with Biomimetic Nanocomposites and Dual-Biomolecular Cross-Linking for Enhanced Antibacterial and Photothermal Therapeutic Effects DOI
Chenxi Du,

Guanghui Gu,

Youyin Xu

et al.

Polymer, Journal Year: 2025, Volume and Issue: unknown, P. 128382 - 128382

Published: April 1, 2025

Language: Английский

Citations

0

Silver Nanoparticle-Induced Nephrotoxicity in Zebrafish (Danio rerio) DOI Open Access
Grace Emily Okuthe,

Busiswa Siguba

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(9), P. 4216 - 4216

Published: April 29, 2025

The escalating challenge of antibacterial resistance has driven the widespread use silver nanoparticles (AgNPs) due to their potent antimicrobial properties. AgNPs can be synthesised through diverse methods, spanning conventional chemical and physical routes increasingly favoured biosynthesis approach. While offering environmental advantages, ecological impact biogenically synthesized AgNPs, especially on aquatic ecosystems, requires thorough evaluation. renal system, critical for maintaining physiological homeostasis via nephron-mediated waste removal, fluid regulation, electrolyte balance, is highly vulnerable toxicant-induced damage, which negatively affect organismal fitness. This study aimed assess nephrotoxic effects using entirely "green" zebrafish after 96-h exposures three distinct concentrations alongside a control group. Acridine orange fluorescence microscopy revealed dose-dependent histopathological alterations in tissues. Specifically, at 0.031 μg/L 0.250 μg/L, significant changes were observed, including glomerular shrinkage, proliferation hematopoietic tissue, dissociation dilation tubules, melanomacrophage aggregation. At 5.000 prolonged exposure beyond 48 h indicated potential tissue cell renewal, suggesting possible compensatory response. These results demonstrate sensitivity kidneys emphasize imperative comprehensive vivo toxicity testing, irrespective synthesis method, accurately evaluate adverse impacts ensure preservation ecosystem integrity.

Language: Английский

Citations

0

Hepatoprotective Properties of Ag Nanoparticles Green‐Formulated by Scrophularia striata in Streptozotocin‐Induced Gestational Diabetes Mellitus Rats DOI
Xiaojian Wei, Yongping Zhang,

Yongqiang Lin

et al.

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(6)

Published: May 14, 2025

ABSTRACT A gestational diabetes mellitus model in rats was created using streptozotocin by intraperitoneal injection, and the post‐synthetically modified biogenic material thoroughly examined various physicochemical techniques, including FTIR, FE‐SEM, XRD, UV–Vis, order to examine impact of silver nanoparticles green‐mediated Scrophularia striata on stereological biochemical parameters diabetic rats. AgNPs 20‐μg/kg 40‐mg/kg, normal pregnancy, groups were randomly assigned 15 For 25 days, administered intragastrically. Serum levels enzymes ALP, ALT, AST, glucose assessed last day. In assess total volume liver its subcompartments, 5‐μm slices produced after tissue processing. may reduce elevated ALP AST enzyme a dose‐dependent way ( p ≤ 0.05). fashion, administration brought these enzymes' back normal. When compared with group, fasting blood level dropped animals treated AgNPs. After receiving large dosage AgNPs, sinusoids hepatocytes, which had been markedly raised streptozotocin, considerably decreased There no significant changes experimental groups' portal vein or bile duct volumes; however, there hepatic artery central volumes AgNPs' hepatoprotective antidiabetic qualities are demonstrated this study, suggests that they might be used as supplement prevent mellitus.

Language: Английский

Citations

0

Defining Acceptance Criteria for Silver Nanoparticles: Correlating Synthesis Quality with Biological Outcomes in an In Vitro Lung Cancer Model DOI Creative Commons
Bárbara Gomes,

Marjorie Dardis Murucci,

Wanderson de Souza

et al.

Nano Trends, Journal Year: 2025, Volume and Issue: 9, P. 100090 - 100090

Published: Feb. 14, 2025

Language: Английский

Citations

0

Silver nanoparticle-assembled guided bone regeneration membranes showcase dual functions: Initial bacterial elimination and subsequent immune regulation DOI Creative Commons
Yu Guo, Fang Li,

Qian Zhang

et al.

Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113882 - 113882

Published: March 1, 2025

Language: Английский

Citations

0