Sclerosis,
Journal Year:
2024,
Volume and Issue:
2(2), P. 77 - 87
Published: March 22, 2024
Cognitive
impairment
is
one
of
the
most
significant
burdens
among
many
neurological
complaints
in
multiple
sclerosis
patients.
deficits
negatively
impact
these
patients’
quality
life,
leading
to
partial
or
total
loss
several
mental
functions,
such
as
learning,
memory,
perception,
problem-solving.
While
precise
mechanisms
involved
onset
and
evolution
cognitive
decline
remain
unknown,
risk
factors
have
been
associated
with
intellectual
disability.
With
increasing
data
on
this
topic
recent
years,
main
aim
review
summarize
relevant
correlated
Firstly,
authors
demonstrate
importance
disability
based
epidemiological
from
patient
cohorts.
Subsequently,
intensely
debated
major
for
are
discussed,
brief
insights
into
pathophysiology
possible
underlying
mechanisms.
Finally,
describe
medication
patients,
highlighting
research
directions
future
studies.
Multiple Sclerosis Journal,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 3, 2025
Background:
Memory
decline
is
common
in
multiple
sclerosis
(MS),
although
pathophysiological
mechanisms
are
not
fully
understood.
Objective:
The
objective
was
to
investigate
the
relationship
of
changes
structural
and
functional
neuroimaging
markers
memory
over
3-year
follow-up.
Methods:
Participants
with
MS
underwent
cognitive
evaluation
structural,
diffusion,
3T
magnetic
resonance
imaging
(MRI)
scans
at
baseline
Changes
metrics
from
follow-up
were
compared
between
stable
groups.
Our
hypothesis
that
connectivity
mediate
association
atrophy
tested.
Results:
A
total
249
patients
completed
visit;
169
(67.8%)
returned
Based
on
⩾10%
decline,
observed
44.4%
(
n
=
75).
Those
showed
marginally
greater
whole-brain
volume
loss
time
those
performance
p
0.08).
In
white
matter
tract
integrity
related
regional
cortical
thinning
<
0.01).
Exploratory
mediation
analysis
revealed
verbal
visual
decline.
Conclusion:
Further
work
needed
characterize
complex
interrelationships
structural/functional
MS.
Neurologia i Neurochirurgia Polska,
Journal Year:
2024,
Volume and Issue:
58(2), P. 176 - 184
Published: Feb. 7, 2024
Cognitive
impairment
occurs
from
the
earliest
stages
of
multiple
sclerosis
(MS)
and
progresses
over
time.
The
introduction
disease
modifying
therapies
(DMTs)
has
changed
prognosis
for
MS
patients,
offering
a
potential
opportunity
improvement
in
cognitive
arena
as
well.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(11), P. 3321 - 3321
Published: June 4, 2024
Multiple
sclerosis
(MS)
is
characterized
by
a
variety
of
symptoms
that
have
major
impact
on
quality
life
(QoL)
even
in
early
stages.
In
addition
to
individual
motor,
sensory,
visual
disturbances,
and
brainstem
sphincter
disorders,
which
are
expressed
through
the
widely
used
Expanded
Disability
Status
Scale
(EDSS),
other
manifestations
MS
detrimental
effect
overall
functioning
life,
such
as
cognitive
impairment,
depression,
anxiety,
fatigue,
pain.
However,
when
talking
about
QoL,
categorical
definitions
cannot
be
because
although
concept
generally
understood,
it
highly
nuanced.
Suffering
from
can
significantly
reduce
QoL.
Numerous
research
studies
focused
trying
identify
assess
elements
most
affect
loss
QoL
people.
fact
measurement
subjective,
very
difficult
consider
these
isolation,
they
interrelated.
One
limiting
factor
has
been
investigated
impairment
(CI).
This
shown
an
lives
people,
different
approaches
taken
CI
evident
limitations.
Journal of Clinical Medicine,
Journal Year:
2023,
Volume and Issue:
12(2), P. 703 - 703
Published: Jan. 16, 2023
Cognitive
impairment
is
a
prevalent
and
debilitating
symptom
of
multiple
sclerosis
(MS)
but
not
routinely
addressed
in
clinical
care.
The
Brief
Assessment
for
Multiple
Sclerosis
(BICAMS)
was
developed
2012
to
screen
monitor
MS
patients’
cognition.
This
systematic
review
meta-analysis
aimed
identify,
synthesise,
critically
appraise
current
BICAMS’
international
validations.
literature
search
conducted
using
PubMed,
PsycINFO
Web
Science
electronic
databases
August
2022.
Quantitative,
peer-reviewed
adult
studies,
which
followed
the
BICAMS
validation
protocol
were
published
English,
included.
identified
total
203
26
eligible
inclusion.
These
reported
2833
adults
with
2382
healthy
controls
(HC).
showed
that
impaired
cognitive
functioning
compared
HC
all
three
subtests:
information
processing
speed
(g
=
0.854,
95%
CI
0.765,
0.944,
p
<
0.001),
immediate
verbal
recall
0.566,
0.459,
0.673,
0.001)
visual
0.487,
0.645,
0.001).
Recruitment
sites
strategies
limit
generalisability
results.
valid
feasible
assessment.
International Journal of Low-Carbon Technologies,
Journal Year:
2025,
Volume and Issue:
20, P. 249 - 268
Published: Jan. 1, 2025
Abstract
Mental
health
challenges,
including
stress,
anxiety,
and
depression,
are
increasingly
prevalent
in
urban
settings,
often
exacerbated
by
inadequate
access
to
well-designed
public
outdoor
spaces
(POS).
This
study
explores
the
relationship
between
POS
mental
outcomes
Al
Madinah
Jeddah,
Saudi
Arabia,
using
a
mixed-methods
approach
involving
literature
review,
case
studies,
surveys.
Findings
reveal
significant
disparities
satisfaction,
with
exhibiting
lower
availability
accessibility.
Despite
better
challenges
remain
widespread
across
both
cities.
Recommendations
emphasize
integrating
neurourbanism
principles
into
planning
create
inclusive,
accessible,
restorative
environments.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(3), P. 438 - 438
Published: Jan. 25, 2025
Background/Objectives:
Persons
with
multiple
sclerosis
(MS)
are
interested
in
diet
as
a
second-line
approach
for
disease
management.
This
study
examined
potential
variables
that
correlate
inaccuracy
of
self-reported
energy
intake
(EI)
adults
MS.
Methods:
Twenty-eight
participants
completed
two
assessment
appointments
within
14-day
period
included
standard
doubly
labeled
water
(DLW)
protocol
estimating
total
expenditure
(TEE).
The
reported
their
EI
using
the
Automated
Self-Administered
24
h
(ASA24)
Dietary
Assessment
Tool.
primary
interest
explaining
discrepancy
between
TEE
and
ASA24
(i.e.,
inaccuracy)
cognition
(processing
speed,
visuospatial
memory,
verbal
memory),
hydration
status
(total
body
water),
device-measured
physical
activity.
Pearson’s
correlations
assessed
association
absolute
percent
reporting
outcomes
interest,
followed
by
linear
regression
analyses
identifying
independent
correlates.
Results:
California
Verbal
Learning
Test—Second
Edition
(CVLT-II)
z-scores
light
activity
(LPA)
were
significantly
associated
mean
difference
(r
=
–0.53
r
0.46,
respectively).
CVLT-II
LPA
only
–0.48
0.42,
indicated
both
explained
variance
EI,
EI.
Conclusions:
results
from
this
indicate
learning
memory
may
guide
timely
research
appropriate
protocols
British Journal of Neuroscience Nursing,
Journal Year:
2025,
Volume and Issue:
21(Sup 1a), P. S8 - S12
Published: March 1, 2025
People
with
multiple
sclerosis
are
being
encouraged
by
healthcare
professionals
to
discuss
earlier
in
their
illnes
wishes
around
future
care
and
treatments.
Some
patients
MS
will
have
significant
symptom
burden
cognitive
function
may
be
impaired.
Future
planning
can
help
extend
autonomy
if
a
person's
capacity
becomes
impaired
ensure
that
decisions
remain
focused
on
the
patient
values.
The
discussions
require
feel
ready
consider
for
future,
involved
need
time
skills
support
them.
of
is
an
opportunity
patients,
families
reach
shared
understanding
patient's
This
article
discusses
opportunities
challenges
introducing
people
journey
sclerosis.
