Prevalence of constipation in adults with obesity class II and III and associated factors

BMC Gastroenterology, Journal Year: 2021, Volume and Issue: 21(1)

Published: May 12, 2021

Constipation and obesity have common risk factors. However, little is known about the occurrence of constipation in individuals with severe associated

Language: Английский

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Plant-derived natural medicines for the management of osteoporosis: A comprehensive review of clinical trials

Journal of Traditional and Complementary Medicine, Journal Year: 2023, Volume and Issue: 14(1), P. 1 - 18

Published: Aug. 5, 2023

Osteoporosis is a chronic and systemic skeletal disease that defined by low bone mineral density (BMD) along with an increase in fragility susceptibility to fracture. This study aimed overview clinical evidence on the use of herbal medicine for management osteoporosis. Electronic databases including Pubmed, Medline, Cochrane library, Scopus were searched until November 2022 any studies efficacy and/or safety plant-derived medicines The search yielded 57 results: 19 single herbs, 16 multi-component preparations, 22 secondary metabolites. Risk fracture, alkaline phosphatase, BMD, specific biomarkers are investigated outcomes these studies. Medicinal plants Acanthopanax senticosus, Actaea racemosa, Allium cepa, Asparagus racemosus, Camellia sinensis, Cissus quadrangularis, Cornus mas, Nigella sativa, Olea europaea, Opuntia ficus-indica, Pinus pinaster, Trifolium pretense phytochemicals isoflavones, ginsenoside, Epimedium prenyl flavonoids, tocotrienols among clinically It seems preparations more effective than single-component ones; because synergistic effects their constituents. demonstrated promising results osteoporosis via targeting different pathways metabolism, balancing osteoblasts osteoclasts, anti-inflammatory, immunomodulatory, antioxidant, estrogen-like functions. have beneficial may manage affecting targets involved osteoporosis; However, Future needed confirm effectiveness preparations.

Language: Английский

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Environmental Factors That Affect Parathyroid Hormone and Calcitonin Levels

International Journal of Molecular Sciences, Journal Year: 2021, Volume and Issue: 23(1), P. 44 - 44

Published: Dec. 21, 2021

Calciotropic hormones, parathyroid hormone (PTH) and calcitonin are involved in the regulation of bone mineral metabolism maintenance calcium phosphate homeostasis body. Therefore, an understanding environmental genetic factors influencing PTH levels is crucial. Genetic estimated to account for 60% variations levels, while background interindividual has not yet been studied. In this review, we analyzed literature discussing influence (lifestyle pollutants) on levels. Among lifestyle factors, smoking, body mass index (BMI), diet, alcohol, exercise were analyzed; among pollutants, heavy metals chemicals analyzed. Lifestyle that showed clearest association with BMI, exercise, micronutrients taken from diet (vitamin D calcium). Smoking, vitamin D, intake led a decrease higher BMI increase terms exposure cadmium lead increased Several studies have investigated effect humans. Compared studies, smaller number which gives great variability results. Only few pollutants The factor relationship was smoking (smokers had levels). Given importance maintaining metabolism, additional could affect

Language: Английский

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Systemic Health Effects of Oleuropein and Hydroxytyrosol Supplementation: A Systematic Review of Randomized Controlled Trials

Antioxidants, Journal Year: 2024, Volume and Issue: 13(9), P. 1040 - 1040

Published: Aug. 27, 2024

Non-communicable diseases (NCDs) cause 41 million deaths annually, accounting for 74% of global fatalities. The so-called Mediterranean diet, with its especially significant consumption olive oil, has shown promising results in reducing the risk developing NCDs, such as cardiovascular, liver, or bone diseases. In context nutritional health benefits foods, phenolic compounds oil's main components, oleuropein (OLE) and hydroxytyrosol (HT), have been to possess different beneficial effects. However, no systematic review evaluated health-promoting effects OLE HT until now. Consequently, this analyzed 12 human randomized controlled trials (RCTs), involving 683 participants, assess supplements, pure compounds, enriched foods containing regarding systemic outcomes, including CVD factors, liver parameters, bone, joint, cognitive health. found contrasting but encouraging results, some studies reporting modulation body weight, lipid profile, glucose metabolism, improvements functions. described dosages forms supplementation, ranging from 5 mg/d 990 mL/d leaf infusion (320.8 mg 11.9 HT), highlighting need further research determine optimal dosing duration. Despite mixed supplementation show potential improving cardiometabolic outcomes are necessary understand their better address existing limitations.

Language: Английский

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Traditional Brazilian diet and extra virgin olive oil reduce symptoms of anxiety and depression in individuals with severe obesity: Randomized clinical trial

Clinical Nutrition, Journal Year: 2020, Volume and Issue: 40(2), P. 404 - 411

Published: June 10, 2020

Language: Английский

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Type 2 Diabetes Mellitus in Class II and III Obesity: Prevalence, Associated Factors, and Correlation between Glycemic Parameters and Body Mass Index

International Journal of Environmental Research and Public Health, Journal Year: 2020, Volume and Issue: 17(11), P. 3930 - 3930

Published: June 2, 2020

Despite the worldwide growth of class II and III obesity, factors associated with type 2 diabetes mellitus (T2DM) in these obese individuals are not widely understood. Moreover, no study has investigated associations South America. Our aimed to investigate prevalence T2DM its factors, an emphasis on biochemical parameters eating habits, individuals. We also analyze correlation between glycemic body mass index (BMI). Baseline data from a randomized clinical trial (DieTBra Trial) 150 (BMI > 35 kg/m

Language: Английский

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Phytoestrogens as Potential Anti-Osteoporosis Nutraceuticals: Major Sources and Mechanism(s) of Action

The Journal of Steroid Biochemistry and Molecular Biology, Journal Year: 2025, Volume and Issue: unknown, P. 106740 - 106740

Published: March 1, 2025

Language: Английский

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The Role of Nutraceuticals and Probiotics in Addition to Lifestyle Intervention in the Management of Childhood Obesity—Part 2: Comorbidities

Nutrients, Journal Year: 2025, Volume and Issue: 17(9), P. 1487 - 1487

Published: April 28, 2025

Pediatric obesity is associated with a wide range of comorbidities beyond metabolic changes, affecting cardiovascular, endocrine, reproductive, musculoskeletal systems, and also mental health. Hypertension, commonly observed in children obesity, increases the risk long-term cardiovascular disease. Polycystic ovary syndrome (PCOS) presents another significant endo-reproductive challenge that often develops during adolescence females, leading to further adulthood. Additionally, excess adiposity can negatively impact bone health by modifying metabolism increasing fracture risk. Obesity strongly linked disorders, including depression, anxiety, low self-esteem, which exacerbate unhealthy lifestyle behaviors disorders. Given limitations poor adherence traditional treatment strategies, nutraceuticals have emerged as potential complementary therapies due their bioactive properties. Various compounds demonstrated antihypertensive, insulin-sensitizing, anti-inflammatory effects, while others support promote well-being. Herewith, we discuss role managing hypertension, PCOS, health, issues individuals evaluating mechanisms action clinical relevance. Integrating nutraceutical dietary interventions may improve outcomes prevent obesity-related comorbidities. Further, emphasize need for large-scale studies, especially pediatric patients.

Language: Английский

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Guide for scientific writing: how to avoid common mistakes in a scientific article

Journal of Human Growth and Development, Journal Year: 2022, Volume and Issue: 32(3), P. 341 - 352

Published: Oct. 31, 2022

Scientific writing is a process requiring dedication, knowledge, and skills from different scientific fields. However, the authors, especially young people starting graduate studies careers, are likely to make some mistakes when writing, which often goes unnoticed. This study describes common in how avoid them. Mistakes can occur before during act of as many authors not familiar with or skip important steps be considered beforehand. To prepare manuscript, it essential that master subject matter research results supported. During author misuses necessary items each section, losing logical sense data making article difficult read. Before begins, is, therefore, plan paragraph use textual techniques ensure cohesion coherence between paragraphs. thus main articles, aiming at improving techniques, optimizing researchers’ time develop an appropriate, clear, elegant text.

Language: Английский

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Effects of Extra Virgin Olive Oil (EVOO) and the Traditional Brazilian Diet on Sarcopenia in Severe Obesity: A Randomized Clinical Trial

Nutrients, Journal Year: 2020, Volume and Issue: 12(5), P. 1498 - 1498

Published: May 21, 2020

Nutritional interventions may have positive effects on sarcopenia and body composition.to evaluate the effectiveness of extra virgin olive oil (EVOO) consumption a healthy traditional Brazilian diet (DieTBra) improving indicators reducing total fat in severe obesity.A randomized controlled trial registered at ClinicalTrials.gov (NCT02463435) conducted with 111 severely obese participants into three treatment groups-(1) EVOO (52 mL/day), (2) DieTBra, (3) DieTBra + mL/day)-for 12 weeks. Body composition was assessed by dual-energy X-ray absorptiometry walking speed handgrip strength.Significant reductions (p = 0.041) weight 0.003) were observed group. In DietBra group there also significant reduction (0.001) compared to oil-only ANCOVA analyses showed 0.016) 0.004) groups. Individuals had improvements their 0.042) strength 0.044).DieTBra contributes strength, speed, adults. The major study (NCT02463435).

Language: Английский

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