Beneficial effects of dietary supplementation with olive oil, oleic acid, or hydroxytyrosol in metabolic syndrome: Systematic review and meta-analysis

Free Radical Biology and Medicine, Journal Year: 2021, Volume and Issue: 172, P. 372 - 385

Published: June 18, 2021

Olive oil and components might have a beneficial effect on Metabolic Syndrome (MetS). The aim of this review meta-analysis was to assess whether those effects are related hydroxytyrosol or oleic acid contents, the combination them as olive oil, how powerful is effect.A systematic literature search performed in MEDLINE via Pubmed, Web Science (WOS) core collection, Virtual Health Library (VHL) LILACS IBECS (Spain). MeSH terms used were "obesity", "body weight", mass index", "adipose tissue", "lipid metabolism", "LDL", "HDL", "VLDL", "insulin resistance", "glucose", "insulin", "hypertension", "arterial pressure", "olive oil", "oleic acid", other (non-MeSH) terms: "total antioxidant capacity", status", "hydroxytyrosol" (PROSPERO ID: CRD42021247614). Results included studies meta-analyzed with RevMan 5.3 program, assuming random model.76 articles (67 different trials) identified. Hydroxytyrosol had no MetS [combined standardized mean differences (SMD) = 0.01 (CI 95%: [-0.23, 0.25], I2 83%; p 0.920)]. Oleic significant [SMD 0.03 [-0.01, 0.07], 0%); 0.150], but it improved lipid profile 0.06 [-0.00, 0.12], 0. 050]. -0.01 [-0.05, 0.03]), 55%; 0.550)]. supplementation hydroxytyrosol, showed capacity 0.31 [-0.34, 0.95], 81%)]; 0.35).Most compared strategies specially designed for management. Our findings suggest that consumption good manage MetS.

Language: Английский

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Inflammaging: The ground for sarcopenia?

Experimental Gerontology, Journal Year: 2022, Volume and Issue: 168, P. 111931 - 111931

Published: Aug. 17, 2022

Language: Английский

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Prevalence of constipation in adults with obesity class II and III and associated factors

BMC Gastroenterology, Journal Year: 2021, Volume and Issue: 21(1)

Published: May 12, 2021

Constipation and obesity have common risk factors. However, little is known about the occurrence of constipation in individuals with severe associated

Language: Английский

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Role of Medical Nutrition Therapy as Treatment of Sarcopenia in Older People with Type 2 Diabetes

Nutrients, Journal Year: 2025, Volume and Issue: 17(1), P. 172 - 172

Published: Jan. 2, 2025

Background: Globally, the progressive increase in aging population has led to social and health problems associated with age-related chronic diseases, such as type 2 diabetes mellitus (T2DM) sarcopenia. Recent studies have highlighted that sarcopenia a bidirectional relationship. Nutritional therapy is key element treatment of both diabetes. To date, there are no nutritional guidelines for management T2DM. The aim this study was evaluate efficacy muscle-targeted intervention older people based on Italian nutrition guidelines. Methods: A total 211 subjects (117 M 94 F) affected by T2DM mean age 74 ± 6.0 years were screened sarcopenia, using EWGSOP2 diagnosis criteria, enrolled receive personalized dietary plans two main targets: daily energy intake 25–30 kcal/kg body weight protein at least 1.1–1.2 g/kg weight. Results: In total, 34 (24 10 sarcopenic prevalence 16%, which higher men. After six months treatment, handgrip strength increased 0.83 kg (19.57 5.70 vs. 20.40 6.10 kg, p = 0.649), improved (0.91 0.28 1.03 0.40 weight, 0.115), glycated hemoglobin decreased (7.39 0.49% 6.82 0.98%, 0.010). Seven younger had an improvement decrease HbA1c (7.50 0.59% 6.91 0.79, 0.19). difference over time consumption saturated fatty acids (OR 0.6, 95% CI 0.33–1.09, 0.096) simple sugars 0.91, 0.80–1.01, 0.090) appeared be status. 177 did not meet criteria 148 assessed. (26.22 9.36 26.18 9.24 p0.974) (7.21 1.07 7.27 0.735) remained stable time, while (0.81 0.29 0.91 0.024). Four diagnosed follow-up, lower test result. These worse glycemic control (HbA1c + 0.5%). Conclusions: Lifestyle modification important prevent or reverse development disease. therefore aimed meeting all needs promoting better control, terms hemoglobin, order reduce Although promising, requires validation larger groups.

Language: Английский

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Is There More to Olive Oil than Healthy Lipids?

Nutrients, Journal Year: 2023, Volume and Issue: 15(16), P. 3625 - 3625

Published: Aug. 18, 2023

The Mediterranean diet is a healthy dietary pattern whose main characteristic olive oil consumption. potential health benefits of have been extensively investigated and the present review provides more recent clinical evidence supporting positive impact intake on human health. PubMed (n = 227) Scopus 308) databases were searched for published studies in English over past six years (October 2016 to December 2022), following key word searches "olive oil" "health". Major findings associated with antioxidant anti-inflammatory effects, improvement endothelial function lipid profile, prevention obesity, diabetes, cardiovascular neurodegenerative diseases, modulation gut microbiota. These are attributed nutritional composition oil, which has high content monounsaturated fatty acids (MUFA) (oleic acid particular) minor compounds such as polyphenols (oleuropein hydroxytyrosol). Although additional research continues be required, recently generated supports contribute beneficially management variety non-communicable consequence synergism between its components' complexity.

Language: Английский

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Extra Virgin Olive Oil (EVOO), a Mediterranean Diet Component, in the Management of Muscle Mass and Function Preservation

Nutrients, Journal Year: 2022, Volume and Issue: 14(17), P. 3567 - 3567

Published: Aug. 30, 2022

Aging results in a progressive decline skeletal muscle mass, strength and function, condition known as sarcopenia. This pathological is due to multifactorial processes including physical inactivity, inflammation, oxidative stress, hormonal changes, nutritional intake. Physical therapy remains the standard approach treat sarcopenia, although some interventions based on dietary supplementation are clinical development. In this context, thanks its anti-inflammatory antioxidative properties, there great interest using extra virgin olive oil (EVOO) promote mass health sarcopenic patients. To date, molecular mechanisms responsible for changes associated with sarcopenia remain undefined; however, complete understanding of signaling pathways that regulate protein synthesis their behavior during appears vital defining how EVOO might attenuate wasting aging. review highlights main players control particular regard discusses, more recent findings, potential delaying/preventing loss aim stimulating further research assess an prevent or delay aging individuals.

Language: Английский

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Traditional Brazilian diet and extra virgin olive oil reduce symptoms of anxiety and depression in individuals with severe obesity: Randomized clinical trial

Clinical Nutrition, Journal Year: 2020, Volume and Issue: 40(2), P. 404 - 411

Published: June 10, 2020

Language: Английский

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Are Dietary Patterns Relevant for Reducing the Risk of Fractures and Sarcopenia?

Current Osteoporosis Reports, Journal Year: 2025, Volume and Issue: 23(1)

Published: Jan. 23, 2025

Language: Английский

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Effects of n-6 PUFA-rich soybean oil, MUFA-rich olive oil and camellia seed oil on weight and cardiometabolic profiles among Chinese women: a 3-month double-blind randomized controlled-feeding trial

Food & Function, Journal Year: 2022, Volume and Issue: 13(8), P. 4375 - 4383

Published: Jan. 1, 2022

Previous studies have suggested that replacing saturated fat with unsaturated is beneficial for cardiometabolic health.

Language: Английский

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Serum and Dietary Vitamin D in Individuals with Class II and III Obesity: Prevalence and Association with Metabolic Syndrome

Nutrients, Journal Year: 2021, Volume and Issue: 13(7), P. 2138 - 2138

Published: June 22, 2021

The association between vitamin D deficiency and metabolic syndrome (MS) in severe obesity is unclear controversial. We analyzed serum dietary their with MS 150 adults class II III (BMI ≥ 35 kg/m2) from the DieTBra Trial (NCT02463435). parameters were high fasting blood glucose, low HDL cholesterol, triglycerides, elevated waist circumference, hypertension. Vitamin was considered as a level < 20 ng/mL. performed multivariate Poisson regression adjusted for sociodemographic lifestyle variables. prevalence of 13.3% (mean 29.9 ± 9.4 ng/mL) median 51.3 IU/day. There no significant associations D, serum, diet variables, lifestyle, obesity. Serum associated age 50 years (p = 0.034). After fully regression, its not or except lower HDL, which (PR 0.71, 95% CI 0.52-0.97; p 0.029). Severe obese individuals had deficiency, MS.

Language: Английский

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