Biological Trace Element Research,
Journal Year:
2023,
Volume and Issue:
201(12), P. 5640 - 5651
Published: March 31, 2023
Zinc
is
a
micronutrient
of
key
importance
for
human
health.
An
increasing
number
studies
indicate
that
zinc
plays
significant
role
in
bone
tissue's
normal
development
and
maintaining
homeostasis.
not
only
component
tissue
but
also
involved
the
synthesis
collagen
matrix,
mineralization,
turnover.
It
has
been
demonstrated
can
stimulate
runt-related
transcription
factor
2
(Runx2)
promote
differentiation
osteoblasts.
On
other
hand,
found
to
inhibit
osteoclast-like
cell
formation
decrease
resorption
by
stimulating
osteoclasts'
apoptosis.
Moreover,
regulates
RANKL/RANK/OPG
pathway,
thereby
facilitating
remodeling.
To
date,
all
mechanisms
Zn
activity
on
are
well
understood
documented.
The
review
aimed
present
current
state
research
tissue,
its
beneficial
properties,
effects
regeneration.
Since
calcium
phosphates
as
substitute
materials
increasingly
enriched
ions,
paper
included
an
overview
potential
such
filling
Frontiers in Nutrition,
Journal Year:
2022,
Volume and Issue:
9
Published: March 9, 2022
Zinc
(Zn)
deficiency
in
humans
is
an
emerging
global
health
issue
affecting
approximately
two
billion
people
across
the
globe.
The
situation
prevails
due
to
intake
of
Zn
deficient
grains
and
vegetables
worldwide.
Clinical
identification
remains
problematic
because
symptoms
do
not
appear
until
impair
vital
organs,
such
as
gastrointestinal
track,
central
nervous
system,
immune
skeletal,
system.
Lower
body
levels
are
also
responsible
for
multiple
physiological
disorders,
apoptosis,
organs
destruction,
DNA
injuries,
oxidative
damage
cellular
components
through
reactive
oxygen
species
(ROS).
causes
chronic
inflammation
lead
toward
several
diseases,
heart
cancers,
alcohol-related
malady,
muscular
contraction,
neuro-pathogenesis.
present
review
focused
on
growth-related
changes
under
conditions,
mechanisms
adopted
by
human
proper
functioning
systems,
importance
nutritional
nutraceutical
approaches
overcome
concluded
that
biofortified
food
best
source
compared
chemical
supplementation
avoid
their
negative
impacts
human.
ACTA HISTOCHEMICA ET CYTOCHEMICA,
Journal Year:
2020,
Volume and Issue:
53(3), P. 33 - 42
Published: June 15, 2020
There
is
a
growing
body
of
evidence
for
the
effects
vitamin
D
on
intestinal
host-microbiome
interactions
related
to
gut
dysbiosis
and
bowel
inflammation.
This
brief
review
highlights
potential
links
between
health,
emphasizing
role
in
microbiological
immunological
mechanisms
inflammatory
diseases.
A
comprehensive
literature
search
was
carried
out
PubMed
Google
Scholar
using
combinations
keywords
"vitamin
D,"
"intestines,"
"gut
microflora,"
"bowel
inflammation".
Only
articles
published
English
study
topic
are
included
review.
We
discuss
how
(a)
modulates
microbiome
function,
(b)
controls
antimicrobial
peptide
expression,
(c)
has
protective
effect
epithelial
barriers
mucosa.
Vitamin
its
nuclear
receptor
(VDR)
regulate
barrier
integrity,
control
innate
adaptive
immunity
gut.
Metabolites
from
microbiota
may
also
expression
VDR,
while
influence
exert
anti-inflammatory
immune-modulating
effects.
The
underlying
mechanism
pathogenesis
diseases
not
fully
understood,
but
maintaining
an
optimal
status
appears
be
beneficial
health.
Future
studies
will
shed
light
molecular
through
which
VDR
affect
mucosal
immunity,
pathogen
invasion,
symbiont
colonization,
expression.
The Tohoku Journal of Experimental Medicine,
Journal Year:
2020,
Volume and Issue:
251(3), P. 175 - 181
Published: Jan. 1, 2020
The
novel
coronavirus
disease
2019
(COVID-19)
is
now
officially
declared
as
a
pandemic
by
the
World
Health
Organization
(WHO),
and
most
parts
of
world
are
taking
drastic
measures
to
restrict
human
movements
contain
infection.
Millions
around
wondering,
if
there
anything
that
could
be
done,
other
than
maintaining
high
personal
hygiene,
vigilant
symptoms,
reduce
spread
chances
getting
infected,
or
at
least
lessen
burden
disease,
caused
severe
acute
respiratory
syndrome
2
(SARS-CoV-2).
National
International
health
agencies,
including
Institutes
(NIH),
Centers
for
Disease
Control
Prevention
(CDC),
WHO
have
provided
clear
guidelines
both
preventive
treatment
suggestions.
In
this
article,
I
will
briefly
discuss,
why
keeping
adequate
zinc
balance
might
enhance
host
response
protective
viral
infections.
Journal of Materials Chemistry B,
Journal Year:
2023,
Volume and Issue:
11(48), P. 11405 - 11425
Published: Jan. 1, 2023
In
this
review,
the
specific
mechanisms
of
bone
formation
promotion
by
Zn-based
biomaterials
are
discussed,
and
recent
developments
in
their
applications
tissue
engineering
summarized.
Journal of Functional Biomaterials,
Journal Year:
2024,
Volume and Issue:
15(7), P. 178 - 178
Published: June 28, 2024
Zinc
is
known
for
its
role
in
enhancing
bone
metabolism,
cell
proliferation,
and
tissue
regeneration.
Several
studies
proposed
the
incorporation
of
zinc
into
hydroxyapatite
(HA)
to
produce
biomaterials
(ZnHA)
that
stimulate
accelerate
healing.
This
systematic
review
aimed
understand
physicochemical
characteristics
zinc-doped
HA-based
evidence
their
biological
effects
on
osteoblastic
cells.
A
comprehensive
literature
search
was
conducted
from
2022
2024,
covering
all
years
publications,
three
databases
(Web
Science,
PUBMED,
Scopus),
retrieving
609
entries,
with
36
articles
included
analysis
according
selection
criteria.
The
selected
provided
data
material’s
properties,
methods
incorporation,
ZnHA
production
typically
involves
wet
chemical
synthesis
HA
precursors,
followed
by
deposition
substrates
using
processes
such
as
liquid
precursor
plasma
spraying
(LPPS).
Characterization
techniques
confirmed
successful
lattice.
findings
indicated
at
low
concentrations
non-cytotoxic
beneficial
found
adhesion,
osteogenic
factors,
thereby
promoting
vitro
mineralization.
However,
optimal
concentration
desired
varied
across
studies,
making
it
challenging
establish
a
standardized
concentration.
materials
are
biocompatible
enhance
osteoblast
proliferation
differentiation.
mechanisms
release
ideal
regeneration
require
further
investigation.
Standardizing
these
parameters
essential
effective
clinical
application
ZnHA.
Frontiers in Nutrition,
Journal Year:
2024,
Volume and Issue:
11
Published: April 19, 2024
Zinc
(Zn)
is
a
vital
micronutrient
that
strengthens
the
immune
system,
aids
cellular
activities,
and
treats
infectious
diseases.
A
deficiency
in
Zn
can
lead
to
an
imbalance
system.
This
particularly
evident
severe
cases,
where
there
high
susceptibility
various
viral
infections,
including
COVID-19
caused
by
SARS-CoV-2.
review
article
examines
nutritional
roles
of
human
health,
maintenance
concentration,
uptake.
As
essential
trace
element
plays
critical
role
system
necessary
for
cell
function
signaling,
cells,
interleukins,
its
SARS-CoV-2
infection
are
further
discussed.
In
summary,
this
paper
encapsulates
with
hope
providing
specific
insights
into
research.
Inflammopharmacology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 5, 2025
Abstract
Across
diverse
cultures,
herbal
remedies
have
been
used
to
alleviate
oral
discomfort
and
maintain
dental
hygiene.
This
review
presents
studies
on
with
remarkable
antimicrobial,
anti-inflammatory,
antioxidant,
anticancer,
anticaries,
analgesic,
healing
properties.
The
manuscripts
demonstrate
the
depth
of
scientific
inquiry
into
for
management
various
health
conditions.
These
include
gingivitis,
ulcers,
mucositis,
periodontitis,
pathogens,
carcinoma,
xerostomia,
caries.
Researchers
investigated
phytochemical
pharmacological
properties
plant-derived
compounds
their
extracts
evaluated
interactions
pathogens
inflammatory
processes.
convergence
traditional
knowledge
rigorous
investigation
offers
a
compelling
narrative,
fostering
deeper
understanding
as
viable
alternatives
conventional
interventions.
work
has
potential
provide
patients
access
gentle,
yet
effective
solutions,
simultaneously
offer
professionals
opportunity
enrich
knowledge,
ability
personalized,
holistic
care.
highlights
symbiotic
relationship
between
medicine
understanding,
emphasizing
importance
disseminating
this
benefit
both
practitioners
patients,
enabling
evidence-based
decision-making
in
exploration
promising
alternative,
potentially
mitigating
some
these
side
effects
while
promoting
more
natural
manner.
