Nutrients,
Journal Year:
2023,
Volume and Issue:
15(9), P. 2227 - 2227
Published: May 8, 2023
Medicinal
mushroom
extracts
(MMEs)
exert
immunomodulatory
effects
on
innate
immunity.
The
present
study
aimed
to
examine
the
effect
of
medicinal
components
in
vitro
immune
cell
responses
inflammatory
stimuli
by
peripheral
blood
mononuclear
cells
(PBMCs)
isolated
from
older
adults,
where
function
is
altered.
PBMCs
were
treated
with
Hericium
coralloides
(HC)
and
Trametes
versicolor
(TV)
prior
stimulation
rhinovirus
A1
(RVA1),
influenza
A/H1N1pdm09
(H1N1),
lipopolysaccharide
(LPS),
or
house
dust
mite
(HDM)
for
48
h.
In
presence
virus,
type
I
II
IFN
significantly
(p
<
0.05)
decreased
following
treatment
at
least
one
concentration
all
compared
untreated
controls,
along
significant
increases
pro-inflammatory
cytokines
(IL-1β,
IL-6,
IL-8).
LPS,
TV
reduced
IL-1β
cells.
HDM,
IL-5
and/or
IL-13
was
dose
extracts.
MMEs
differential
release
antiviral
mediators
vitro.
Reduced
2
cytokine
HDM
may
be
beneficial
conditions
allergic
inflammation
present,
including
asthma,
rhinitis,
eczema.
Further
research
needed
vivo.
Food Production Processing and Nutrition,
Journal Year:
2022,
Volume and Issue:
4(1)
Published: Oct. 13, 2022
Abstract
Seaweed
has
emerged
as
one
of
the
most
promising
resources
due
to
its
remarkable
adaptability,
short
development
period,
and
resource
sustainability.
It
is
an
effective
breakthrough
alleviate
future
crises.
Algal
have
reached
a
high
stage
growth
in
past
years
increased
output
demand
for
seaweed
worldwide.
Several
aspects
global
farming
production
processing
over
last
20
are
reviewed,
such
latest
situation
approaches
farming.
Research
progress
trend
various
application
discussed.
Besides,
challenges
faced
by
also
analyzed,
related
countermeasures
proposed,
which
can
provide
advice
processing.
The
primary
products,
extraction
application,
or
waste
utilization
would
bring
greater
benefits
with
continuous
improvement
applications
fields.
Graphical
Fungal Diversity,
Journal Year:
2023,
Volume and Issue:
121(1), P. 95 - 137
Published: July 1, 2023
Abstract
Fungi
provide
ecological
and
environmental
services
to
humans,
as
well
health
nutritional
benefits,
are
vital
numerous
industries.
Fermented
food
beverage
products
from
fungi
circulating
in
the
market,
generating
billions
of
USD.
However,
highest
potential
monetary
value
is
their
role
blue
carbon
trading
because
ability
sequester
large
amounts
soil.
There
no
conclusive
estimates
available
on
global
fungi,
primarily
there
limited
data
for
extrapolation.
This
study
outlines
contribution
economy
provides
a
first
attempt
at
quantifying
fungi.
Our
estimate
USD
54.57
trillion
starting
point
that
can
be
analysed
improved,
highlighting
significance
providing
an
appreciation
value.
paper
identifies
different
economically
valuable
provided
by
By
giving
all
important
fungal
products,
services,
industrial
applications
underscores
biodiversity
conservation.
Furthermore,
if
established,
they
will
considered
future
policies
effective
ecosystem
management.
Sustainability,
Journal Year:
2022,
Volume and Issue:
14(9), P. 4941 - 4941
Published: April 20, 2022
Global
food
production
faces
many
challenges,
including
climate
change,
a
water
crisis,
land
degradation,
and
desertification.
These
challenges
require
research
into
non-traditional
sources
of
human
foods.
Edible
mushrooms
are
considered
an
important
next-generation
healthy
source.
rich
in
proteins,
dietary
fiber,
vitamins,
minerals,
other
bioactive
components
(alkaloids,
lactones,
polysaccharides,
polyphenolic
compounds,
sesquiterpenes,
sterols,
terpenoids).
Several
ingredients
can
be
extracted
from
edible
incorporated
health-promoting
supplements.
It
has
been
suggested
that
several
diseases
treated
with
extracts
mushrooms,
as
these
have
biological
effects
anticancer,
antidiabetic,
antiviral,
antioxidant,
hepatoprotective,
immune-potentiating,
hypo-cholesterolemic
influences.
The
current
study
focuses
on
sustainable
approaches
for
handling
their
secondary
metabolites,
biofortification.
Comparisons
between
poisonous
well
the
common
species
different
ingredients,
crucial.
Nutritional
values
health
benefits
biomedical
applications,
also
emphasized.
Further
is
needed
to
explore
economic
sustainability
medicinal
mushroom
compound
potential
applications
against
emerging
such
COVID-19.
New
nano-biofortification
supply
essential
nutrients
and/or
increase
ingredients.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(8), P. 1913 - 1913
Published: April 15, 2023
The
last
century
has
seen
an
increase
in
our
life
expectancy.
As
a
result,
various
age-related
diseases,
such
as
neurodegenerative
diseases
(NDs),
have
emerged,
representing
new
challenges
to
society.
Oxidative
stress
(OS),
condition
of
redox
imbalance
resulting
from
excessive
production
reactive
oxygen
species,
represents
common
feature
that
characterizes
the
brains
elderly
people,
thus
contributing
NDs.
Consequently,
antioxidant
supplementation
or
dietary
intake
antioxidant-containing
foods
could
represent
effective
preventive
and
therapeutic
intervention
maintain
integrity
survival
neurons
counteract
pathologies
associated
with
aging.
Food
contains
numerous
bioactive
molecules
beneficial
actions
for
human
health.
To
this
purpose,
wide
range
edible
mushrooms
been
reported
produce
different
compounds
phenolics,
flavonoids,
polysaccharides,
vitamins,
carotenoids,
ergothioneine,
others,
which
might
be
used
enhance
defenses
and,
consequently,
prevention
neurological
diseases.
In
review,
we
summarized
role
oxidative
NDs,
focusing
on
current
knowledge
present
mushrooms,
highlighting
their
potential
preserve
healthy
aging
by
counteracting
age-associated
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(4), P. 507 - 507
Published: Feb. 10, 2024
The
escalating
prevalence
of
metabolic
and
cardiometabolic
disorders,
often
characterized
by
oxidative
stress
chronic
inflammation,
poses
significant
health
challenges
globally.
As
the
traditional
therapeutic
approaches
may
sometimes
fall
short
in
managing
these
conditions,
attention
is
growing
toward
nutraceuticals
worldwide;
with
compounds
being
obtained
from
natural
sources
potential
beneficial
effects
shown
to
potentially
support
and,
some
cases,
replace
pharmacological
treatments,
especially
for
individuals
who
do
not
qualify
conventional
treatments.
This
review
delves
into
burgeoning
field
nutraceutical-based
modulation
as
a
promising
strategy
attenuating
inflammation
disorders.
Drawing
an
extensive
body
research,
showcases
various
nutraceutical
agents,
such
polyphenols,
omega-3
fatty
acids,
antioxidants,
which
exhibit
antioxidative
anti-inflammatory
properties.
All
can
be
classified
novel
drugs
that
are
capable
regulating
pathways
mitigate
oxidative-stress-
inflammation-associated
diseases.
By
exploring
mechanisms
through
interact
immune
responses,
this
highlights
their
restore
redox
balance
temper
inflammation.
Additionally,
prospects
interventions
discussed,
encompassing
bioavailability
enhancement,
personalized
treatment
approaches,
clinical
translation.
Through
comprehensive
analysis
latest
scientific
reports,
article
underscores
avenue
fight
complex
landscape
particularly
accentuating
impact
on
cardiovascular
health.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(3), P. e25607 - e25607
Published: Feb. 1, 2024
Ganoderma
lucidum
is
a
versatile
mushroom.
Polysaccharides
and
triterpenoids
are
the
major
bioactive
compounds
have
been
used
as
traditional
medicinal
mushrooms
since
ancient
times.
They
currently
nutraceuticals
functional
foods.
G.
extracts
their
an
alternative
to
antioxidants
antimicrobial
agents.
Secondary
metabolites
with
many
properties
make
it
possible
substitute
that
could
be
applied
immunomodulatory,
anticancer,
antimicrobial,
anti-oxidant,
anti-inflammatory,
anti-diabetic.
The
miraculous
of
secondary
fascinate
researchers
for
development
production.
Recent
studies
paid
close
attention
different
physical,
genetic,
biochemical,
nutritional
parameters
potentiate
production
metabolites.
This
review
effort
collect
biologically
active
constituents
from
reveal
potential
actions
against
diseases
latest
improvement
in
novel
technique
get
maximum
Studies
going
ahead
determine
efficacy
numerous
assess
valuable
achieved
by
favor
antioxidant
outcomes.
RSC Advances,
Journal Year:
2023,
Volume and Issue:
13(12), P. 8049 - 8089
Published: Jan. 1, 2023
Microorganisms
still
remain
the
main
hotspots
in
global
drug
discovery
avenue.
In
particular,
fungi
are
highly
prolific
producers
of
vast
structurally
diverse
specialized
secondary
metabolites,
which
have
displayed
a
myriad
biomedical
potentials.
Intriguingly,
isocoumarins
is
one
distinctive
class
fungal
natural
products
polyketides,
demonstrated
numerous
remarkable
biological
and
pharmacological
activities.
This
review
article
provides
comprehensive
state-of-the-art
over
period
2000-2022
about
discovery,
isolation,
classifications,
therapeutic
potentials
exclusively
reported
from
fungi.
Indeed,
list
351
were
documented
classified
according
to
their
sources
[16
order/28
family/55
genera]
where
they
been
originally
discovered
along
with
activities
wherever
applicable.
Also,
recent
insights
around
proposed
experimentally
proven
biosynthetic
pathways
also
briefly
discussed.
Marine Drugs,
Journal Year:
2023,
Volume and Issue:
21(5), P. 273 - 273
Published: April 27, 2023
Seaweed
has
been
known
to
possess
beneficial
effects
forhuman
health
due
the
presence
of
functional
bioactive
components.
The
n-butanol
and
ethyl
acetate
extracts
Dictyota
dichotoma
showed
ash
(31.78%),
crude
fat
(18.93%),
protein
(14.5%),
carbohydrate
(12.35%)
contents.
About
19
compounds
were
identified
in
extract,
primarily
undecane,
cetylic
acid,
hexadecenoic
Z-11-,
lageracetal,
dodecane,
tridecane,
whereas
25
mainly
tetradecanoic,
myristic
acid.
FT-IR
spectroscopy
confirmed
carboxylic
phenols,
aromatics,
ethers,
amides,
sulfonates,
ketones.
Moreover,
total
phenolic
contents
(TPC)
flavonoid
(TFC)
extract
2.56
2.51
mg
GAE/g
2.11
2.25
QE/g,
respectively.
Ethyl
at
a
high
concentration
100
mL−1
66.64
56.56
%
inhibition
DPPH,
Antimicrobial
activity
revealed
that
Candida
albicans
was
most
susceptible
microorganism,
followed
by
Bacillus
subtilis,
Staphylococcus
aureus,
Escherichia
coli,
Pseudomonas
aeruginosa
least
all
concentrations.
vivo
hypoglycemic
study
both
exhibited
concentration-dependent
activities.
In
conclusion,
this
macroalgae
antioxidant,
antimicrobial,
potentials.
Discover Materials,
Journal Year:
2024,
Volume and Issue:
4(1)
Published: May 19, 2024
Abstract
The
increasing
global
population
and
rapid
urbanization
have
led
to
high
consumer
demand
for
construction
other
raw
materials.
Manufacturing
of
synthetic
material
usually
generate
a
large
amount
waste,
resulting
in
significant
environmental
impact.
Fungi
are
one
the
key
biological
resources
that
can
be
used
develop
wide
range
sustainable
products
including
biodegradable
materials
with
promising
applications,
zero
waste
generation
during
production
process.
Mycelium,
vegetative
part
fungus
shaped
either
into
pure
mycelium
or
composites.
Mycelium
grow
its
network
lignocellulosic
material,
combining
separate
pieces
solid
which
results
Mycelium-Based
Composites
(MBCs).
attributes
MBCs
influenced
by
fungal
species,
growth
substrate,
processing
conditions.
Both
remarkable
advantages
as
versatile
because
they
porous,
elastic,
low-density,
low-cost
eco-friendly
potential
applications
various
industries.
In
this
review,
we
provide
an
overview
latest
developments
considering
possibility
using
material-driven
design
(MDD)
approach,
genetic
biochemical
modifications
enhance
properties.
We
therefore
encourage
researchers
science
biotechnology
strengthen
their
collaborative
efforts
address
current
challenges
innovative
field.