Frontiers in Nutrition,
Journal Year:
2022,
Volume and Issue:
9
Published: July 22, 2022
Poor
sleep
quality
and
vitamin
D
deficiency
are
common
in
stroke
patients.
Our
aim
was
to
evaluate
the
possible
association
between
acute
ischemic
(AIS)
A
total
of
301
AIS
patients
were
screened
completed
1-month
follow-up.
Serum
25-hydroxyvitamin
[25(OH)D]
used
assess
status
by
a
competitive
protein-binding
assay
at
baseline.
All
divided
into
equal
quartile
according
distribution
25(OH)D.
One
month
after
stroke,
evaluated
using
Pittsburgh
Sleep
Quality
Index
(PSQI)
Epworth
Sleepiness
Scale
(ESS)
questionnaire;
depression
confirmed
17-item
Hamilton
Depression
(HAMD).
There
89
(29.6%)
with
poor
post-event.
Within
24
h
admission,
serum
25(OH)D
levels
significantly
lower
(P
<
0.001).
In
results
multivariate-adjusted
logistic
regression
analysis,
odds
ratio
(OR)
6.199
(95%
CI,
2.066-18.600)
for
lowest
compared
highest
quartile.
without
depression,
reduced
still
associated
(OR
=
8.174,
95%
CI
2.432-27.473).
Furthermore,
HAMD
score
combined
enhance
diagnostic
accuracy
quality,
area
under
receiver
operating
characteristic
curve
0.775.
Reduced
admission
independently
1
stroke.
findings
suggested
combination
could
provide
important
predictive
information
post-stroke
quality.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(2), P. 277 - 277
Published: Jan. 14, 2025
Vitamin
D
offers
numerous
under-recognized
health
benefits
beyond
its
well-known
role
in
musculoskeletal
health.
It
is
vital
for
extra-renal
tissues,
prenatal
health,
brain
function,
immunity,
pregnancy,
cancer
prevention,
and
cardiovascular
Existing
guidelines
issued
by
governmental
organizations
are
bone-centric
largely
overlook
the
abovementioned
extra-skeletal
optimal
thresholds
vitamin
D.
In
addition,
they
rely
on
randomized
controlled
trials
(RCTs),
which
seldom
show
due
to
high
baseline
25-hydroxyvitamin
[25(OH)D]
concentrations,
moderate
supplementation
doses,
flawed
study
designs.
This
review
emphasizes
findings
from
prospective
cohort
studies
showing
that
higher
25(OH)D
concentrations
reduce
risks
of
major
diseases
mortality,
including
pregnancy
birth
outcomes.
Serum
>
30
ng/mL
(75
nmol/L)
significantly
lower
disease
mortality
compared
<20
ng/mL.
With
25%
U.S.
population
60%
Central
Europeans
having
levels
ng/mL,
should
be
raised
above
achievable
through
daily
with
2000
IU/day
(50
mcg/day)
D3,
prevent
deaths.
Furthermore,
a
dose
between
4000
6000
IU
D3
achieve
serum
40
70
would
provide
greater
protection
against
many
adverse
Future
recommendations
integrate
observational
well-designed
RCTs
improve
public
personalized
care.
Journal of Cardiovascular Development and Disease,
Journal Year:
2024,
Volume and Issue:
11(7), P. 204 - 204
Published: June 30, 2024
A
prevalent
condition
linked
to
an
elevated
risk
of
cardiovascular
disease
is
sleep
apnea.
This
review
examines
the
connections
between
cardiac
risk,
sympathetic
nervous
system,
and
The
increased
hypertension,
arrhythmias,
myocardial
infarction,
heart
failure
was
highlighted
in
pathophysiology
apnea
its
effect
on
activation.
It
also
important
consider
potential
processes
such
as
oxidative
stress,
inflammation,
endothelial
dysfunction,
autonomic
imbalance
that
may
relate
apnea-induced
activation
risk.
With
implications
for
creating
innovative
diagnostic
treatment
approaches
lessen
effects
apnea,
goal
this
investigation
improve
understanding
intricate
link
activity,
study
aimed
clarify
complex
relationship
health
by
synthesizing
available
research
highlighting
crucial
role
played
system
moderating
relationship.
Our
thorough
have
therapeutic
ramifications
will
direct
creation
focused
therapies
enhance
outcomes
sufferers.
International Journal of Environmental Research and Public Health,
Journal Year:
2023,
Volume and Issue:
20(5), P. 4431 - 4431
Published: March 1, 2023
Patients
with
a
generalized
anxiety
disorder
(GAD)
often
report
preeminent
sleep
disturbances.
Recently,
calcium
homeostasis
gained
interest
because
of
its
role
in
the
regulation
sleep-wake
rhythms
and
symptoms.
This
cross-sectional
study
aimed
at
investigating
association
between
imbalance,
anxiety,
quality
patients
GAD.
A
total
211
were
assessed
using
Hamilton
Rating
Scale
for
Anxiety
(HAM-A),
Pittsburgh
Sleep
Quality
Index
questionnaire
(PSQI)
Insomnia
Severity
(ISI)
scales.
Calcium,
vitamin
D,
parathyroid
hormone
(PTH)
levels
evaluated
blood
samples.
correlation
linear
regression
analysis
run
to
evaluate
HAM-A,
PSQI,
ISI
scores
peripheral
markers
imbalance.
Significant
correlations
emerged
ISI,
PTH,
D.
The
models
showed
that
GAD
displaying
low
D
higher
PTH
exhibit
poor
subjective
underpinning
psychopathological
burden.
strong
relationship
biomarkers
insomnia,
quality,
symptomatology
was
underlined.
Future
studies
could
shed
light
on
causal
temporal
metabolism
sleep.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: April 7, 2024
To
evaluate
association
of
vitamin
D
with
sleep
quality
in
adults
and
the
influence
VDR-gene
polymorphism
FokI
(rs2228570;A
>
G).
Cross-sectional
population-based
study
adults,
conducted
Brazil.
The
outcome
was
sleep-quality,
evaluated
by
Pittsburgh
Sleep
Quality
Index.
Vitamin
determined
indirect
electrochemiluminescence
classified
as
deficiency
(VDD),
25(OH)D
<
20
ng/mL
a
healthy
population
or
30
for
groups
at
risk
VDD.
genotyped
qPCR
homozygous
wild
(FF
AA),
heterozygous
(Ff
AG),
mutant
(ff
GG).
Multivariate
logistic
analysis
used
to
estimate
between
sleep-quality.
In
total
1674
individuals
evaluated,
53.6%
had
poor-sleep-quality,
31.5%
VDD,
genotype
frequency
9.9%
FF,
44.6%
Ff,
45.5%
ff.
multivariate
analysis,
VDD
1.51
times
chance
ff
1.49
poor-sleep-quality
(OR:1.49;95%CI:1.05-2.12)
when
compared
FF
Ff
genotype.
combined
more
than
sufficient
(OR:2.19;95%CI:1.27-3.76).
Our
data
suggest
that
VDR
gene
are
associated
combining
two
factors
increases
separate
groups.
Occupational and Environmental Medicine,
Journal Year:
2025,
Volume and Issue:
unknown, P. oemed - 109968
Published: Feb. 25, 2025
Objectives
Evaluate
vitamin
D
levels
in
Portuguese
active-duty
Navy
military
personnel
during
winter
and
explore
the
relationship
between
occupational
settings
levels,
as
well
fatigue,
sleep
health,
burnout.
Methods
All
who
collected
a
blood
sample
at
Naval
Medicine
Centre
of
2023–2024
were
included
cross-sectional
study.
Serum
25-hydroxy-vitamin
(25(OH)D),
calcium,
phosphorus
parathyroid
hormone
added
to
their
analysis
request.
They
asked
complete
questionnaire
that
questions
about
work,
sun
exposure,
D-rich
foods
and/or
supplements
or
medication
intake,
health
Blood
samples
processed
Clinical
Pathology
Service
Armed
Forces
Hospital.
T-test/median
test
z-test
applied
compare
homologous
means/medians
prevalences,
respectively.
Results
Of
735
participants,
42.2%,
41.1%
16.7%
deficient,
insufficient
sufficient,
The
median
serum
25(OH)D
level
was
significantly
lower
(p<0.001),
deficiency
prevalence
higher
(p=0.000)
‘onboard’
‘indoors’
groups,
‘mixed
shifts’
group
(p=0.030;
p=0.004).
Median
not
statistically
different
groups
with
without
poor
personal
work-related
Conclusions
high
personnel,
winter,
especially
those
working
onboard,
indoors
mixed
shifts,
must
be
addressed
by
services.
Future
research
should
include
submariners.
Annals of Pediatric Endocrinology & Metabolism,
Journal Year:
2025,
Volume and Issue:
30(1), P. 3 - 10
Published: Feb. 26, 2025
In
recent
years,
studies
have
revealed
that
vitamin
D,
a
steroid
hormone
essential
for
calcium
and
phosphorus
metabolism,
also
plays
role
in
sleep.
Adequate
levels
of
D
been
linked
to
improved
sleep
quality
children
effective
prevention
problems.
This
report
is
review
summary
research
on
the
significance
sleep,
stages
children's
impact
Additionally,
this
explores
mechanisms
through
which
improves
