Hydrogen-Rich Water to Enhance Exercise Performance: A Review of Effects and Mechanisms DOI Creative Commons

Qiaorui Zhou,

Huixin Li, Ye Zhang

et al.

Metabolites, Journal Year: 2024, Volume and Issue: 14(10), P. 537 - 537

Published: Oct. 7, 2024

: Hydrogen-rich water (HRW) has garnered significant interest within the sports and exercise science community due to its selective antioxidant properties. Despite potential benefits, comprehensive reviews specifically addressing effects on athletic performance are limited. This review aims assess impact of HRW explore underlying molecular biological mechanisms, with goal elucidating how might enhance performance.

Language: Английский

Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease DOI Open Access
Cai‐Mei Zheng, Yi‐Chou Hou, Min-Tser Liao

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2024, Volume and Issue: 176, P. 116802 - 116802

Published: May 24, 2024

Oxidative stress plays a key role in chronic kidney disease (CKD) development and progression, inducing cell damage, inflammation, fibrosis. However, effective therapeutic interventions to slow down CKD advancement are currently lacking. The multifaceted pharmacological effects of molecular hydrogen (H2) have made it promising avenue. H2 is capable capturing harmful •OH ONOO- while maintaining the crucial reactive oxygen species (ROS) involved cellular signaling. NRF2-KEAP1 system, which manages redox balance, could be used treat CKD. activates this pathway, fortifying antioxidant defenses scavenging ROS counteract oxidative stress. can improve NRF2 signaling by using Wnt/β-catenin pathway indirectly activate mitochondria. Additionally, modulates NF-κB activity regulating status, inhibiting MAPK pathways, Trx levels. Treatment with also attenuates HIF neutralizing bolstering HIF-1α function. Furthermore, affects FOXO factors enhances enzymes. Despite encouraging results bench studies, clinical trials still limited require further investigation. focus review on hydrogen's treating renal diseases, specific regulation, discusses its potential applications.

Language: Английский

Citations

10
Hydrogen-rich water alleviates asthma airway inflammation by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation DOI
Li Li Li, Ziqian Xu,

Haoran Ni

et al.

Free Radical Biology and Medicine, Journal Year: 2024, Volume and Issue: 224, P. 50 - 61

Published: Aug. 13, 2024

Language: Английский

Citations

6
Thyroid-associated ophthalmopathy: the role of oxidative stress DOI Creative Commons
Chao Ma, Haoyu Li, Shuwen Lu

et al.

Frontiers in Endocrinology, Journal Year: 2024, Volume and Issue: 15

Published: July 11, 2024

Thyroid-associated ophthalmopathy (TAO) is an autoimmune condition affecting the eyes, characterized by proptosis, extraocular muscle involvement, and in severe cases, vision impairment including diplopia, optic neuropathy, potential blindness. The exact etiology of TAO remains elusive; however, increased oxidative stress decreased antioxidant capacity are pivotal its pathogenesis. Elevated not only directly damages orbital tissues but also influences thyroid function responses, exacerbating tissue destruction. This review explores role TAO, elucidates mechanisms, evaluates efficacy limitations therapies managing TAO. findings aim to enhance understanding mechanisms propose strategies for future therapeutic development.

Language: Английский

Citations

4
The Effect of Hydrogen-Rich Water on Retinal Degeneration in the Outer Nuclear Layer of Simulated Weightlessness Rats DOI

Yuxue Mu,

Wenhao Li,

Dongyu Wei

et al.

Life Sciences in Space Research, Journal Year: 2025, Volume and Issue: 45, P. 158 - 169

Published: March 16, 2025

Language: Английский

Citations

0
Hydrogen inhalation therapy for inflammation and eye diseases: a review of the literature DOI
Yoshiyasu Takefuji

Eye, Journal Year: 2024, Volume and Issue: 38(13), P. 2497 - 2498

Published: April 18, 2024

Language: Английский

Citations

2
Hydrogen-Rich Water to Enhance Exercise Performance: A Review of Effects and Mechanisms DOI Creative Commons

Qiaorui Zhou,

Huixin Li, Ye Zhang

et al.

Metabolites, Journal Year: 2024, Volume and Issue: 14(10), P. 537 - 537

Published: Oct. 7, 2024

: Hydrogen-rich water (HRW) has garnered significant interest within the sports and exercise science community due to its selective antioxidant properties. Despite potential benefits, comprehensive reviews specifically addressing effects on athletic performance are limited. This review aims assess impact of HRW explore underlying molecular biological mechanisms, with goal elucidating how might enhance performance.

Language: Английский

Citations

1