Advances in logistics, operations, and management science book series,
Journal Year:
2024,
Volume and Issue:
unknown, P. 37 - 49
Published: May 3, 2024
3D
printing
is
crucial
to
the
healthcare
industry's
ability
quickly
produce
customized
instruments
and
medical
equipment.
Customizing
supplies
equipment
one
of
main
advantages
in
field.
Prostheses
implants
particular
have
profited
immensely.
At
some
time,
technology
could
advance
point
where
failing
organs
might
be
replaced
with
specially
designed,
entirely
new
structures.
The
combination
stem
cell
research
potentially
lead
functioning
organs,
including
kidneys,
livers,
or
hearts,
using
patient's
own
cells.
This
may
shorten
wait
periods
for
viable
do
away
need
organ
donors.
process
offers
several
significant
over
traditional
donation,
such
as
lack
rejection
risk,
result
production
healthy,
fully
functional
organs.
applications
are
almost
limitless.
Complex,
organic
constructions
like
porous
metal
parts
thin
scaffolds
that
mimic
structure
bones
made.
Personalized
a
cost-effective
alternative
mass
inspires
plethora
innovative
applications.
Instead
creating
hundreds
identical
components,
additive
manufacturing
makes
it
possible
create
prosthetic
orthotic
devices
specifically
tailored
anatomy
each
patient,
boosting
their
effectiveness.
AAPS PharmSciTech,
Journal Year:
2023,
Volume and Issue:
24(8)
Published: Nov. 14, 2023
Abstract
This
review
explores
recent
advancements
and
applications
of
3D
printing
in
healthcare,
with
a
focus
on
personalized
medicine,
tissue
engineering,
medical
device
production.
It
also
assesses
economic,
environmental,
ethical
considerations.
In
our
the
literature,
we
employed
comprehensive
search
strategy,
utilizing
well-known
databases
like
PubMed
Google
Scholar.
Our
chosen
keywords
encompassed
essential
topics,
including
printing,
nanotechnology,
related
areas.
We
first
screened
article
titles
abstracts
then
conducted
detailed
examination
selected
articles
without
imposing
any
date
limitations.
The
for
inclusion,
comprising
research
studies,
clinical
investigations,
expert
opinions,
underwent
meticulous
quality
assessment.
methodology
ensured
incorporation
high-quality
sources,
contributing
to
robust
exploration
role
realm
healthcare.
highlights
printing's
potential
customized
drug
delivery
systems,
patient-specific
implants,
prosthetics,
biofabrication
organs.
These
innovations
have
significantly
improved
patient
outcomes.
Integration
nanotechnology
has
enhanced
precision
biocompatibility.
demonstrates
cost-effectiveness
sustainability
through
optimized
material
usage
recycling.
healthcare
sector
witnessed
remarkable
progress
promoting
patient-centric
approach.
From
implants
radiation
shielding
offers
tailored
solutions.
Its
transformative
applications,
coupled
economic
viability
sustainability,
revolutionize
Addressing
biocompatibility,
standardization,
concerns
is
responsible
adoption.
Graphical
European Polymer Journal,
Journal Year:
2024,
Volume and Issue:
215, P. 113251 - 113251
Published: June 19, 2024
Meeting
the
escalating
demands
in
biomedical
applications
has
spurred
creation
of
diverse
scaffolds,
where
selection
materials
and
manufacturing
techniques
stands
as
a
linchpin
fostering
bone
tissue
formation.
These
scaffolds
provide
fundamental
structural
framework
that
supports
cell
growth
differentiation.
It
is
vital
for
repair,
addressing
various
biological
requisites
such
biocompatibility,
biodegradability,
mechanical
properties
becomes
imperative.
This
comprehensive
review
discusses
recent
advancements
3D
tailored
specifically
engineering
applications.
Stereolithography,
fused
deposition
modelling,
selective
laser
sintering,
binder
jetting,
electron
beam
melting,
bioprinting
(including
laser-based,
inkjet
extrusion
bioprinting)
are
meticulously
explored.
Focusing
on
their
respective
applications,
limitations,
well
advantages
disadvantages
within
context
regeneration.
Furthermore,
article
underscores
pivotal
role
material
potential
solution
to
address
challenges
associated
with
grafts.
emphasizes
need
nuanced
understanding
significant
considerations
regardless
type
when
designing
or
evaluating
suitability
integration
into
expansive
realm
engineering.
Advances in healthcare information systems and administration book series,
Journal Year:
2024,
Volume and Issue:
unknown, P. 132 - 152
Published: Feb. 14, 2024
Among
the
various
manufacturing
processes
currently
in
use
by
industry,
3D
printing
stands
out
as
a
unique
additive
technique.
It
enables
creation
of
three-dimensional
solid
objects
virtually
any
shape
from
digital
model.
Initially
considered
an
ambitious
concept,
medical
has
become
reality
thanks
to
substantial
time
and
investment.
This
chapter
delves
into
recent
advancements
within
modern
field,
offering
concise
overview
how
why
is
transforming
practices,
education,
research.
serves
introduction
subject,
followed
demonstration
state-of-the-art
through
industry
developments.
The
significance
this
lies
its
comprehensive
coverage
evolving
role
healthcare,
highlighting
not
only
current
applications
challenges
but
also
underscoring
potential
revolutionize
aspects
science
patient
care.
Nano-Micro Letters,
Journal Year:
2024,
Volume and Issue:
16(1)
Published: Aug. 13, 2024
Abstract
The
eye,
a
complex
organ
isolated
from
the
systemic
circulation,
presents
significant
drug
delivery
challenges
owing
to
its
protective
mechanisms,
such
as
blood-retinal
barrier
and
corneal
impermeability.
Conventional
administration
methods
often
fail
sustain
therapeutic
levels
may
compromise
patient
safety
compliance.
Polysaccharide-based
microneedles
(PSMNs)
have
emerged
transformative
solution
for
ophthalmic
delivery.
However,
comprehensive
review
of
PSMNs
in
ophthalmology
has
not
been
published
date.
In
this
review,
we
critically
examine
synergy
between
polysaccharide
chemistry
microneedle
technology
enhancing
ocular
We
provide
thorough
analysis
PSMNs,
summarizing
design
principles,
fabrication
processes,
addressed
during
fabrication,
including
improving
comfort
also
describe
recent
advances
performance
various
both
research
clinical
scenarios.
Finally,
current
regulatory
frameworks
market
barriers
that
are
relevant
commercial
advancement
final
perspective
on
area.
Gels,
Journal Year:
2025,
Volume and Issue:
11(2), P. 89 - 89
Published: Jan. 23, 2025
Transdermal
drug
delivery
minimizes
pain
and
provides
a
controlled,
stable
release
of
drugs,
but
its
effectiveness
is
limited
by
the
skin’s
natural
barriers.
Microneedles
overcome
this
problem,
enabling
minimally
invasive
delivery.
Microneedle
patches
(MNPs)
with
80
µm-tall
needles
composed
hyaluronic
acid
(HA)
were
developed
evaluated
for
their
formability,
structural
integrity,
dissolution
rate,
skin
penetration
ability,
transmission
capacity.
The
influence
molecular
weight
HA
on
these
properties
was
also
investigated.
MNPs
made
from
low-molecular-weight
(30
kDa–50
kDa)
demonstrated
12.5
times
superior
permeability
in
ex
vivo
human
compared
to
needleless
(NLPs).
Furthermore,
same
test,
had
1.7
higher
than
high-molecular-weight
MNPs,
suggesting
transdermal
administration.
significantly
influenced
solubility
permeability,
highlighting
potential
as
systems.
Puncture
tests
depth
50–60
µm,
indicating
minimal
nerve
irritation
dermis
effective
superficial
dermal
layer.
These
results
present
manufacturing
technique
incorporating
model
compounds
highlight
novel
method
biomedical
applications
soft
gels.
Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
17(3), P. 375 - 375
Published: March 15, 2025
Recent
progress
in
material
science
has
led
to
the
development
of
new
drug
delivery
systems
that
go
beyond
conventional
approaches
and
offer
greater
accuracy
convenience
application
therapeutic
agents.
This
review
discusses
evolutionary
role
nanocarriers,
hydrogels,
bioresponsive
polymers
enhanced
release,
target
accuracy,
bioavailability.
Oncology,
chronic
disease
management,
vaccine
are
some
applications
explored
this
paper
show
how
these
materials
improve
results,
counteract
multidrug
resistance,
allow
for
sustained
localized
treatments.
The
also
translational
barriers
bringing
advanced
into
clinical
setting,
which
include
issues
biocompatibility,
scalability,
regulatory
approval.
Methods
overcome
challenges
surface
modifications
reduce
immunogenicity,
scalable
production
methods
such
as
microfluidics,
harmonization
systems.
In
addition,
convergence
artificial
intelligence
(AI)
machine
learning
(ML)
is
opening
frontiers
personalized
medicine.
These
technologies
predictive
modeling
real-time
adjustments
optimize
needs
individual
patients.
use
can
be
applied
rare
underserved
diseases;
thus,
strategies
gene
therapy,
orphan
drugs
development,
global
distribution
may
hopes
millions
Micromachines,
Journal Year:
2025,
Volume and Issue:
16(2), P. 155 - 155
Published: Jan. 29, 2025
Dermal
drug
delivery
presents
a
significant
challenge
for
poorly
soluble
active
compounds
like
curcumin,
which
often
struggle
to
penetrate
the
skin
barrier
effectively.
In
this
study,
dermal
penetration
efficacy
of
curcumin
nanocrystals
and
bulk
suspensions
when
applied
using
microneedles
varying
lengths-0.25
mm,
0.5
1.0
mm-was
investigated
in
an
ex
vivo
porcine
ear
model.
The
findings
revealed
that
all
formulations,
conjunction
with
microneedle
application,
facilitated
transepidermal
penetration;
however,
combination
demonstrated
highest
efficacy.
Notably,
mm
length
provided
optimal
penetration,
significantly
enhancing
compared
alone.
Additionally,
even
use
0.25
resulted
high
level
efficiency,
indicating
shorter
can
still
effectively
facilitate
delivery.
Overall,
study
underscores
potential
technology
improving
absorption
actives
suggesting
integration
could
enhance
therapeutic
effects
topical
applications.
Advanced Healthcare Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 29, 2025
Abstract
Current
early
cancer
diagnostic
technologies,
such
as
imaging,
molecular
tests,
endoscopic
techniques,
and
biopsies,
face
considerable
challenges
in
low‐and
middle‐income
countries
(LMICs)
due
to
high
costs,
procedural
complexity,
limited
resource
access.
Microneedle‐based
liquid
biopsy
for
skin
interstitial
fluid
(ISF)
offers
a
practical
minimally
invasive
alternative
diagnosis
these
settings.
This
review
systematically
examines
ISF
methods
their
effectiveness
capturing
biomarkers
directly
from
the
assesses
potential
address
needs
low‐resource
environments.
Recent
innovations
microneedle
design
underscore
enabling
early,
accessible
detection
tailored
LMICs'
needs.
Additionally,
integrating
artificial
intelligence
(AI)
data
interpretation
is
proposed
way
enhance
accuracy
enable
real‐time
point‐of‐care
(POC)
applications.
Collectively,
advances
illustrate
flexible,
scalable
model
diagnostics,
with
significant
implications
improving
healthcare
quality
resource‐limited
