Exploring the Therapeutic Potential for Breast Cancer of Phytochemicals and Secondary Metabolites in Marjoram, Thyme, and Persimmon DOI Creative Commons

Aubrey Anne Mattingly,

Zoe Vickery,

Diana Ivankovic

et al.

Metabolites, Journal Year: 2024, Volume and Issue: 14(12), P. 652 - 652

Published: Nov. 25, 2024

: Breast cancer is the most common cause of death in women worldwide and commonly diagnosed cancer. Although several therapeutic approaches are widely used against breast cancer, their adverse effects often lead to symptoms severely affecting quality life. Alternative methods have been explored reduce these effects, nutraceuticals yielded promising results. This review will discuss mechanisms action potential applications some nutraceuticals, specifically marjoram, thyme, persimmon leaves.

Language: Английский

Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health DOI
Alice Njolke Mafe, Great Iruoghene Edo, Patrick Othuke Akpoghelie

et al.

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Language: Английский

Citations

7

Phytochemical-mediated modulation of signaling pathways: A promising avenue for drug discovery DOI Creative Commons

Jibon Kumar Paul,

Mahir Azmal,

ANM Shah Newaz Been Haque

et al.

Advances in Redox Research, Journal Year: 2024, Volume and Issue: 13, P. 100113 - 100113

Published: Aug. 31, 2024

Language: Английский

Citations

9

Natural Compounds for Preventing Age-Related Diseases and Cancers DOI Open Access
Mi‐Ran Ki,

Sol Youn,

Dong Hyun Kim

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(14), P. 7530 - 7530

Published: July 9, 2024

Aging is a multifaceted process influenced by hereditary factors, lifestyle, and environmental elements. As time progresses, the human body experiences degenerative changes in major functions. The external internal signs of aging manifest various ways, including skin dryness, wrinkles, musculoskeletal disorders, cardiovascular diseases, diabetes, neurodegenerative cancer. Additionally, cancer, like aging, complex disease that arises from accumulation genetic epigenetic alterations. Circadian clock dysregulation has recently been identified as an important risk factor for cancer development. Natural compounds herbal medicines have gained significant attention their potential preventing age-related diseases inhibiting progression. These demonstrate antioxidant, anti-inflammatory, anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects well circadian regulation. This review explores cancers, specific natural targeting key features these conditions.

Language: Английский

Citations

8

Green synthesis of silver and gold nanoparticles using quercetin extracted from Arctium lappa by HPLC, Characterization and Estimation of antioxidant activity DOI Creative Commons

Mahmood Zaki Lafta,

Rafah Razooq Hameed Al-Samarrai, ‪Mohamed Bouaziz

et al.

Results in Chemistry, Journal Year: 2025, Volume and Issue: 13, P. 102028 - 102028

Published: Jan. 1, 2025

Language: Английский

Citations

1

Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review DOI
Yasser Fakri Mustafa

Indian Journal of Clinical Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Language: Английский

Citations

1

Nutritional qualities of cookies made from wheat/cashew nut composite flour DOI
Joseph Oghenewogaga Owheruo, Great Iruoghene Edo,

Raghda Makia

et al.

Food and Humanity, Journal Year: 2024, Volume and Issue: 3, P. 100452 - 100452

Published: Nov. 16, 2024

Language: Английский

Citations

6

Critical review on plant-derived quorum sensing signaling inhibitors in pseudomonas aeruginosa DOI
Kayeen Vadakkan, Kuppusamy Sathishkumar,

Viji Ouseph Mapranathukaran

et al.

Bioorganic Chemistry, Journal Year: 2024, Volume and Issue: 151, P. 107649 - 107649

Published: July 15, 2024

Language: Английский

Citations

4

In-vitro approaches to evaluate the anti-inflammatory potential of phytochemicals: A Review DOI Open Access
S. Sabalingam

Journal of Drug Delivery and Therapeutics, Journal Year: 2025, Volume and Issue: 15(1), P. 187 - 192

Published: Jan. 15, 2025

Phytochemicals, bioactive compounds derived from plants, have drawn considerable attention for their ability to modulate inflammatory pathways, presenting promising alternatives the treatment of chronic diseases. Inflammation, a complex biological response injury or infection, involves cascade cellular and molecular events mediated by enzymes, cytokines, reactive species. In vitro assays provide an essential platform screening investigating anti-inflammatory potential phytochemicals, offering valuable insights into mechanisms action. Commonly used techniques include inhibition protein denaturation membrane stabilization, which evaluate prevent structural damage proteins cell membranes. Enzymatic assays, such as cyclooxygenase (COX) 5-lipoxygenase (5-LOX) tests, focus on suppression key enzymes involved in arachidonic acid metabolism, thereby reducing production pro-inflammatory mediators like prostaglandins leukotrienes. Other proteinase hyaluronidase assess block contributing tissue degradation inflammation. These offer robust, reproducible frameworks evaluating phytochemicals preclinical research, helping identify with therapeutic value. However, limitations, lack vivo context inter-assay variability, necessitate integration complementary studies validate findings understand translational significance. Keywords: methods, activity, denaturation, stabilization

Language: Английский

Citations

0

Phytochemical-based nanosystems: recent advances and emerging application in antiviral photodynamic therapy DOI
Yan Shan Loo,

Nur Aininie Yusoh,

Wai Feng Lim

et al.

Nanomedicine, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 16

Published: Jan. 23, 2025

Phytochemicals are typically natural bioactive compounds or metabolites produced by plants. Phytochemical-loaded nanocarrier systems, designed to overcome bioavailability limitations and enhance therapeutic effects, have garnered significant attention in recent years. The coronavirus disease 2019 (COVID-19) pandemic has intensified interest the application of phytochemicals combat viral infections. This review explores nanoparticle-based treatment strategies incorporating for antiviral application, highlighting their demonstrated mechanisms. It specifically examines activities phytochemical-loaded nanosystems against (i) influenza virus (IAV), respiratory syncytial (RSV), severe acute syndrome 2 (SARS-CoV-2); (ii) mosquito-borne viruses [dengue (DENV), Zika (ZIKV), Chikungunya (CHIKV)]; (iii) sexually transmitted/blood borne [e.g. herpes simplex (HSV), human papillomavirus (HPV), immunodeficiency (HIV)]. Furthermore, this highlights emerging role these photodynamic therapy (PDT)-mediated attenuation proliferation, offers a perspective on future directions research promising area multimodal approach.

Language: Английский

Citations

0

Phytochemicals in plant food waste: innovative insight and implications DOI Creative Commons
Ifrah Usman,

Saima Sana,

Muhammad Afzaal

et al.

Journal of Agriculture and Food Research, Journal Year: 2025, Volume and Issue: unknown, P. 101779 - 101779

Published: Feb. 1, 2025

Language: Английский

Citations

0