Ultrasonics Sonochemistry,
Journal Year:
2021,
Volume and Issue:
82, P. 105887 - 105887
Published: Dec. 22, 2021
Ultrasound
(US)
demonstrates
remarkable
potential
in
synthesising
nanomaterials,
particularly
nanobiomaterials
targeted
towards
biomedical
applications.
This
review
briefly
introduces
existing
top-down
and
bottom-up
approaches
for
nanomaterials
synthesis
their
corresponding
mechanisms,
followed
by
the
expounding
of
US-driven
synthesis.
Subsequently,
pros
cons
sono-nanotechnology
its
advances
are
drawn
based
on
recent
works.
US-synthesised
have
improved
properties
performance
over
conventional
methods
most
essentially
eliminate
need
harsh
expensive
chemicals.
The
sonoproduction
different
classes
types
such
as
metal
superparamagnetic
nanoparticles
(NPs),
lipid-
carbohydrate-based
NPs,
protein
microspheres,
microgels
other
nanocomposites
broadly
categorised
physical
and/or
chemical
effects
induced
US.
ends
a
good
note
recognises
pragmatic
solution
to
satisfy
growing
demand
nanobiomaterials,
nonetheless
some
technical
challenges
highlighted.
Pharmaceutics,
Journal Year:
2021,
Volume and Issue:
13(10), P. 1666 - 1666
Published: Oct. 12, 2021
Wound
dressings
have
become
a
crucial
treatment
for
wound
healing
due
to
their
convenience,
low
cost,
and
prolonged
management.
As
cutting-edge
biomaterials,
marine
polysaccharides
are
divided
from
most
organisms.
It
possesses
various
bioactivities,
which
allowing
them
be
processed
into
forms
of
dressings.
Therefore,
comprehensive
understanding
the
application
in
is
particularly
important
studies
therapy.
In
this
review,
we
first
introduce
process
describe
characteristics
modern
commonly
used
Then,
properties
dressing
development
outlined.
Finally,
strategies
developing
enhancing
polysaccharide
described,
an
outlook
these
given.
The
diverse
bioactivities
including
antibacterial,
anti-inflammatory,
haemostatic
properties,
etc.,
providing
excellent
management
accelerate
healing.
Meanwhile,
biomaterials
higher
biocompatibility
biodegradability
compared
synthetic
ones.
On
other
hand,
can
combined
with
copolymers
active
substances
prepare
Among
them,
emerging
types
such
as
nanofibers,
smart
hydrogels
injectable
at
research
frontier
development.
essential
materials
fabrication
promising
future.
International Journal of Molecular Sciences,
Journal Year:
2022,
Volume and Issue:
23(15), P. 8778 - 8778
Published: Aug. 7, 2022
Wound
dressing
design
is
a
dynamic
and
rapidly
growing
field
of
the
medical
wound-care
market
worldwide.
Advances
in
technology
have
resulted
development
wide
range
wound
dressings
that
treat
different
types
wounds
by
targeting
four
phases
healing.
The
ideal
should
perform
rapid
healing;
preserve
body's
water
content;
be
oxygen
permeable,
non-adherent
on
hypoallergenic;
provide
barrier
against
external
contaminants-at
reasonable
cost
with
minimal
inconvenience
to
patient.
Therefore,
choosing
best
based
what
needs
does
achieve
complete
regeneration
restoration
skin's
structure
function.
Biopolymers,
such
as
alginate
(ALG),
chitosan
(Cs),
collagen
(Col),
hyaluronic
acid
(HA)
silk
fibroin
(SF),
are
extensively
used
management
due
their
biocompatibility,
biodegradability
similarity
macromolecules
recognized
human
body.
However,
most
formulations
biopolymers
still
show
various
issues;
thus,
strategies
combine
them
molecular
biology
approaches
represent
future
this
article
provides
an
overview
biopolymers'
roles
physiology
perspective
new
generation
enhanced,
naturally
inspired,
smart
blood
products,
stem
cells
growth
factors.
Deleted Journal,
Journal Year:
2023,
Volume and Issue:
5(1)
Published: Oct. 23, 2023
Abstract
The
skin
plays
a
fundamental
role
in
regulating
the
body’s
internal
balance
and
protecting
against
external
traumas.
A
broad
variety
of
environmental
risk
factors
frequently
result
acute
wounds,
whose
inappropriate
treatments
would
lead
to
chronic
wounds
that
are
difficult
heal.
Traditional
dressings
have
been
widely
used
repair
however
their
drawbacks
such
as
insufficient
hemostatic
efficacy
non-moist
environment
severely
limited
clinical
applications.
As
principal
component
skin,
collagen
has
always
research
hotspot
field
due
its
advantages
low
antigenicity,
high
biocompatibility
superior
bioactivity.
Collagen-based
increasingly
developed
heal
during
past
decades,
arising
from
capability
decreasing
protein
electrolyte
losses
wound
exudate,
preventing
bacterial
contamination,
permitting
less
painful
dressing
changes,
improving
healing
quality.
This
review
overviews
recent
progress
for
healing.
Various
commonly
management
first
introduced.
Collagen
categorized
films,
sponges,
hydrogels,
nanofibers,
powders,
compared.
critical
functions
healing,
stopping
bleeding,
shortening
inflammation,
promoting
angiogenesis,
stimulating
tissue
regeneration
elaborated.
applications
different
types
thoroughly
summarized.
comprehensive
list
commercialized
updated,
an
outlook
finally
speculated.
Graphical
Molecules,
Journal Year:
2023,
Volume and Issue:
28(2), P. 604 - 604
Published: Jan. 6, 2023
Globally,
millions
of
people
suffer
from
poor
wound
healing,
which
is
associated
with
higher
mortality
rates
and
healthcare
costs.
There
are
several
factors
that
can
complicate
the
healing
process
wounds,
including
inadequate
conditions
for
cell
migration,
proliferation,
angiogenesis,
microbial
infections,
prolonged
inflammatory
responses.
Current
therapeutic
methods
have
not
yet
been
able
to
resolve
primary
problems;
therefore,
their
effectiveness
limited.
As
a
result
remarkable
properties,
bio-based
materials
demonstrated
significant
impact
on
in
recent
years.
In
microenvironment,
stimulate
numerous
cellular
molecular
processes
may
enhance
by
inhibiting
growth
pathogens,
preventing
inflammation,
stimulating
potentially
converting
non-healing
environment
an
appropriately
one.
The
aim
this
present
review
article
provide
overview
mechanisms
underlying
its
pathophysiology.
development
nanomaterials
chronic
diabetic
wounds
as
well
novel
methodologies
also
discussed.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: April 27, 2024
Abstract
The
development
of
innovative
wound
dressing
materials
is
crucial
for
effective
care.
It’s
an
active
area
research
driven
by
a
better
understanding
chronic
pathogenesis.
Addressing
care
properly
clinical
challenge,
but
there
growing
demand
advancements
in
this
field.
synergy
medicinal
plants
and
nanotechnology
offers
promising
approach
to
expedite
the
healing
process
both
acute
wounds
facilitating
appropriate
progression
through
various
phases.
Metal
nanoparticles
play
increasingly
pivotal
role
promoting
efficient
preventing
secondary
bacterial
infections.
Their
small
size
high
surface
facilitate
enhanced
biological
interaction
penetration
at
site.
Specifically
designed
topical
drug
delivery,
these
enable
sustained
release
therapeutic
molecules,
such
as
growth
factors
antibiotics.
This
targeted
ensures
optimal
cell-to-cell
interactions,
proliferation,
vascularization,
fostering
controlled
healing.
Nanoscale
scaffolds
have
significant
attention
due
their
attractive
properties,
including
delivery
capacity,
porosity
area.
They
mimic
Extracellular
matrix
(ECM)
hence
biocompatible.
In
response
alarming
rise
antibiotic-resistant,
biohybrid
nanofibrous
dressings
are
gradually
replacing
conventional
antibiotic
systems.
emerging
class
comprises
biopolymeric
nanofibers
with
inherent
antibacterial
nature-derived
compounds,
biofunctional
agents.
Nanotechnology,
diminutive
nanomaterials,
nanoscaffolds,
nanofibers,
biomaterials
harnessed
aimed
review
article
discusses
effects
loaded
on
healing,
(in
vivo
vitro)
mechanical
outcomes.
Graphical
Journal of Polymer Engineering,
Journal Year:
2024,
Volume and Issue:
44(2), P. 83 - 116
Published: Jan. 27, 2024
Abstract
Biopolymer-based
nanocomposites
have
gained
significant
attention
in
biomedicine
due
to
their
unique
properties
and
potential
applications.
These
combine
biopolymers,
natural
polymers
derived
from
renewable
sources,
with
nanoparticles
or
other
nanoscale
materials
create
enhanced
functionalities.
Biopolymers
that
are
used
make
bio-nanocomposites
cellulose,
alginate,
chitosan,
starch,
polylactic
acid
(PLA),
polyhydroxyalkanoate
(PHA),
polyhydroxybutyrate
(PHB),
etc.
different
properties,
they
can
be
several
types
of
treatments.
Scaffolds
frequently
employ
acid-gelatin,
nanocellulose,
chitosan.
Studies
shown
some
special
hydrogel
films
proven
beneficial
anticancer
treatment.
Synthetic
naturally
occurring
substances
such
as
PLA,
polyvinyl
alcohol
(PVA),
guar
gum,
chitosan
employed
the
drug
delivery
system.
Nanocomposites
silver
sulfated
polysaccharides,
thyme-loaded
carrot
nanocellulose
starch
biopolymer
been
stop
bacterial
development.
This
review
article
provides
a
comprehensive
insight
into
biopolymer-based
uses.
Also,
it
has
incorporated
fields
biosensors,
bioimaging,
blood
clotting,
immunomodulation,
antibacterial
antiviral
drugs,
food
packaging.
Hence,
primary
objective
this
is
provide
an
overall
perspective
on
nanomedicine.
