Science and Technology of Engineering Chemistry and Environmental Protection,
Journal Year:
2024,
Volume and Issue:
1(10)
Published: Dec. 31, 2024
Plastic
has
been
a
pressing
subject
for
discussion
ever
since
its
invention.
It
is
extremely
convenient
to
use
and
produce.
However,
plastic
poses
increasingly
problematic
threats
both
the
health
of
environment
public.
Especially
microplastic
nano
plastic,
which
are
byproducts
degradation
large
pieces
plastic.
These
smaller
can
infiltrate
bodies
animals
travel
up
food
chain,
detrimentally
affecting
ecosystem.
Furthermore,
when
enters
humans
through
consumption
respiration,
it
causes
an
array
problems.
The
endocrine
system
malfunction
due
harmful
chemicals
added
into
present
in
microplastic.
To
solve
this
issue,
more
policies
should
be
made
regarding
treatment
amount
produced,
teaching
population
about
issues
This
paper
provides
depth
research
cause
pandemic,
that
inflict,
potential
solutions
combat
these
Marine Pollution Bulletin,
Journal Year:
2024,
Volume and Issue:
202, P. 116338 - 116338
Published: April 18, 2024
Comprehensive
methodologies
for
monitoring
microplastics
(MPs)
in
the
ocean
are
critical
accurately
assessing
abundances
across
a
broad
size
spectrum,
and
to
document
distributions,
sources,
sinks,
temporal
trends,
exposure
risks
organisms.
Discrete
0.5-L
water
samples
from
northeastern-coast
of
Venezuela
(NECV),
Pacific-Arctic
Ocean
(PAO),
Gulf
Stream
Current
(GSC)
were
analyzed
by
Raman
microspectroscopy
detect
MPs
not
captured
net-tow
surveys.
Equivalent
spherical
diameters
(ESD)
most
<5
μm,
accounting
68,
83,
86
%
total
inventories
NECV,
GSC,
PAO
samples.
We
did
observe
single
MP
particle
>53
μm
ESD.
Abundances
0.5–200
fraction
5–6
orders
magnitude
higher
than
previous
surveys
that
almost
exclusively
based
on
net
tow
collections
>
300
NECV
~10-fold
those
GSC.
The
abundant
polymers
polypropylene
(PP),
polystyrene
(PS)
polyethylene
terephthalate
(PET),
consistent
with
composition
plastic
waste
generated
globally.
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
949, P. 174881 - 174881
Published: July 22, 2024
The
ubiquitous
and
global
ecological
footprint
arising
from
the
rapidly
increasing
rates
of
plastic
production,
use,
release
into
environment
is
an
important
modern
environmental
issue.
Of
concern
are
risks
associated
with
at
least
16,000
chemicals
present
in
plastics,
some
which
known
to
be
toxic,
may
leach
out
both
during
use
once
exposed
conditions,
leading
human
exposure.
In
response,
United
Nations
member
states
agreed
establish
international
legally
binding
instrument
on
pollution,
plastics
treaty.
resolution
acknowledges
that
treaty
should
prevent
pollution
its
related
impacts,
effective
prevention
requires
consideration
transboundary
nature
full
life
cycle
must
addressed.
As
a
group
scientific
experts
members
Scientists'
Coalition
for
Effective
Plastics
Treaty,
we
concur
there
six
essential
"pillars"
necessary
truly
reduce
allow
chemical
detoxification
across
plastics.
These
include
reduction
simplification,
safe
sustainable
design
chemicals,
incentives
change,
holistic
approaches
alternatives,
just
transition
equitable
interventions,
centering
rights.
There
critical
need
scientifically
informed
globally
harmonized
information,
transparency,
traceability
criteria
protect
public
health.
right
clean,
healthy,
upheld,
thus
it
crucial
scientists,
industry,
policy
makers
work
concert
create
future
free
hazardous
contamination.
Brain Sciences,
Journal Year:
2024,
Volume and Issue:
14(5), P. 471 - 471
Published: May 7, 2024
Plastic
production,
which
exceeds
one
million
tons
per
year,
is
of
global
concern.
The
constituent
low-density
polymers
enable
spread
over
large
distances
and
micro/nano
particles
(MNPLs)
induce
organ
toxicity
via
digestion,
inhalation,
skin
contact.
Particles
have
been
documented
in
all
human
tissues
including
breast
milk.
MNPLs,
especially
weathered
particles,
can
breach
the
blood–brain
barrier,
inducing
neurotoxicity.
This
has
non-human
species,
human-induced
pluripotent
stem
cell
lines.
Within
brain,
MNPLs
initiate
an
inflammatory
response
with
pro-inflammatory
cytokine
oxidative
stress
generation
reactive
oxygen
mitochondrial
dysfunction.
Glutamate
GABA
neurotransmitter
dysfunction
also
ensues
alteration
excitatory/inhibitory
balance
favor
reduced
inhibition
resultant
neuro-excitation.
Inflammation
cortical
hyperexcitability
are
key
abnormalities
involved
pathogenic
cascade
amyotrophic
lateral
sclerosis
(ALS)
intricately
related
to
mislocalization
aggregation
TDP-43,
a
hallmark
ALS.
Water
many
foods
contain
humans,
ingestion
main
form
exposure.
Digestion
plastics
within
gut
alter
their
properties,
rendering
them
more
toxic,
they
cause
microbiome
dysbiosis
dysfunctional
gut–brain
axis.
recognized
as
trigger
and/or
aggravating
factor
for
ALS
associated
long
(years
or
decades)
preclinical
period
neonates
infants
exposed
through
milk,
milk
substitutes,
toys.
endangers
time
intense
neurogenesis
establishment
neuronal
circuitry,
setting
stage
development
neurodegeneration
later
life.
MNPL
neurotoxicity
should
be
considered
yet
unrecognized
risk
diseases.
Archives of Environmental Contamination and Toxicology,
Journal Year:
2024,
Volume and Issue:
87(1), P. 48 - 57
Published: June 19, 2024
Abstract
Plastics
are
synthetic
organic
compounds
whose
widespread
use
generates
enormous
waste.
Different
processes,
such
as
mechanical
abrasion,
microbiological
activity,
and
UVB
irradiation,
can
fragment
the
plastic
material
generate
microplastics
(MPs).
MPs
ubiquitous,
various
organisms,
including
humans,
ingest
or
inhale
them,
with
potential
adverse
health
effects.
The
differences
between
UV-aged
virgin
particles
were
studied
to
evaluate
genotoxic
damage
oxidative
stress
induced
by
polystyrene
1
5
µm
sizes
on
monocyte-like
cell
line
(THP-1).
Fourier
transform
infrared
spectroscopy
Ζ-potential
measurements
used
characterise
MP
after
exposure.
Cells
exposed
show
a
change
in
cellular
environment
generation
of
reactive
species
(ROS),
indicated
increased
malondialdehyde
level.
occurrence
is
correlated
smaller
size
ageing
state
MPs.
biochemical
genomic
alterations
observed
this
vitro
study
suggest
that
MPs,
ubiquitous
pollutants,
following
natural
degradation
oxidation
processes
cause
effects
population,
making
it
necessary
carry
out
further
studies
better
define
real
risk.
Phytotherapy Research,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 24, 2025
ABSTRACT
The
human
body
gets
exposed
to
a
variety
of
toxins
intentionally
or
unintentionally
on
regular
basis
from
sources
such
as
air,
water,
food,
and
soil.
Certain
can
be
synthetic,
while
some
are
biological.
affect
the
various
parts
by
activating
numerous
pro‐inflammatory
markers,
like
oxidative
stresses,
that
tend
disturb
normal
function
organs
ultimately.
Nowadays,
people
use
different
types
herbal
treatments,
viz.,
drinks
contain
spices
for
detoxification
their
bodies.
One
example
is
turmeric,
most
commonly
available
spice
in
kitchen
used
across
all
kinds
households.
Turmeric
contains
curcumin,
which
natural
polyphenol.
Curcumin
medicinal
compound
with
biological
activities,
antioxidant,
antineoplastic,
anti‐inflammatory,
antibacterial.
Hence,
this
review
gives
comprehensive
insight
into
promising
potential
curcumin
heavy
metals,
carbon
tetrachloride,
drugs,
alcohol,
acrylamide,
mycotoxins,
nicotine,
plastics.
encompasses
diverse
animal‐based
studies
portraying
curcumin's
role
nullifying
toxic
effects
(especially
liver,
kidney,
testicles,
brain)
enhancing
defensive
signaling
pathways,
improving
antioxidant
enzyme
levels,
inhibiting
markers
activities
so
on.
Furthermore,
also
argues
over
safety
assessment
its
utilization
detoxifying
agent.
BIO Web of Conferences,
Journal Year:
2025,
Volume and Issue:
154, P. 01003 - 01003
Published: Jan. 1, 2025
This
study
aims
to
identify
the
distribution
and
frequency
of
microplastics
in
sediment
water
Coban
Kethak,
a
source
Malang,
Indonesia.
Recreation,
recreation
with
sanitary
facilities,
durian
plantation,
paddy
fields
were
four
sites
from
where
samples
taken,
each
represented
distinct
set
human-caused
features.
Wet
peroxide
oxidation
density
separation
procedures
used
extract
microplastics,
which
seen
identified
using
stereomicroscopy.
PCA
clustering
analyzed
PAST
software
main
patterns
variation
microplastic
among
locations.
found
that
all
smaller
than
3
μm
size,
different
shapes:
fibers,
pieces,
films,
microbeads.
Microplastic
concentrations
(84
particles/100g)
(68
particles/50L)
highest
at
recreational
location
lowest
field
region
(0
sample
44
particles/50L
sample,
respectively).
According
principal
component
analysis
cluster
analysis,
shows
contamination
is
associated
human
activities,
areas
being
most
affected.
these
findings,
further
targeted
solutions
are
needed
decrease
freshwater
ecosystems,
especially
places
heavy
activity.
