Biology,
Journal Year:
2022,
Volume and Issue:
11(11), P. 1622 - 1622
Published: Nov. 6, 2022
Non-alcoholic
fatty
liver
disease
(NAFLD)
is
a
prevalent,
multifactorial,
and
poorly
understood
with
an
increasing
incidence
worldwide.
NAFLD
typically
asymptomatic
coupled
other
symptoms
of
metabolic
syndrome.
The
prevalence
rising
in
tandem
the
obesity.
In
Western
hemisphere,
one
most
prevalent
causes
transplantation.
Recent
research
suggests
that
gut
microbiome
dysbiosis
may
play
significant
role
pathogenesis
by
dysregulating
gut–liver
axis.
so-called
“gut–liver
axis”
refers
to
communication
feedback
loop
between
digestive
system
liver.
Several
pathological
mechanisms
characterized
alteration
axis,
such
as
impairment
barrier
increase
intestinal
permeability
which
result
endotoxemia
inflammation,
changes
bile
acid
profiles
metabolite
levels
produced
microbiome.
This
review
will
explore
axis
disruption,
mediated
dysbiosis,
on
development.
Frontiers in Public Health,
Journal Year:
2022,
Volume and Issue:
10
Published: April 25, 2022
Mental
disorders
(e.g.,
depression)
and
sedentary
behavior
are
increasing,
also
among
emerging
adults.
One
particular
target
group
of
adults
with
high
sitting
times
vulnerability
to
mental
university
students.
In
particular,
anxiety
depressive
symptoms
as
well
stress
very
common
The
present
manuscript
discusses
whether
physical
activity
exercise
interventions
can
help
promote
the
health
such
will
summarize
current
scientific
evidence
based
on
this
evidence,
introduce
an
university-based
research
project
that
investigates
if
activity,
acute
bouts
low-
moderate
intensity
buffer
perceived
stress,
alleviate
strengthen
well-being
(psychologically
physiologically)
students
by
positively
influencing
symptoms,
emotion
perception,
body
awareness
subjective
including
overall
quality
life.
project,
its
concept,
multimethod
approach,
first
results
from
available
studies
discussed
in
relation
care
needs
future
developments.
conducted
within
so
far
briefly
summarized
suggest
related,
important
further
comprising
aerobic
exercises
may
work
best
improve
(alleviate
stress)
after
a
few
weeks
intervention.
addition,
certain
types
(yoga
particular)
seem
be
particularly
effective
changing
perception
bodily
signals,
cardiac
processing
immediately
exercise.
underscore
importance
systematic
investigations
combined
examination
psychological
physiological
factors
active
lifestyle
Frontiers in Cardiovascular Medicine,
Journal Year:
2022,
Volume and Issue:
9
Published: Aug. 22, 2022
Atherosclerosis
is
a
predecessor
of
numerous
cardiovascular
diseases
(CVD),
which
often
lead
to
morbidity
and
mortality.
Despite
the
knowledge
pathogenesis
atherosclerosis,
an
essential
gap
in
our
understanding
exact
trigger
mechanism.
A
wide
range
risk
factors
have
been
discovered;
however,
majority
them
are
too
general
clarify
launching
mechanism
atherogenesis.
Some
permanent
(age,
gender,
genetic
heritage)
others
can
be
modified
[tobacco
smoking,
physical
inactivity,
poor
nutrition,
high
blood
pressure,
type
2
diabetes
(T2D),
dyslipidemia,
obesity].
All
taken
into
account.
In
scope
this
review,
attention
focused
on
hypertension,
considered
most
widespread
among
all
modifiable
for
atherosclerosis
development.
Moreover,
pressure
investigated
factor.
The
purpose
review
summarize
data
hypertension
as
factor
development
assessment.
Frontiers in Immunology,
Journal Year:
2024,
Volume and Issue:
15
Published: Jan. 26, 2024
The
gut
microbiome
is
a
heterogeneous
population
of
microbes
comprising
viruses,
bacteria,
fungi,
and
protozoa.
Such
essential
for
sustaining
host
equilibrium,
its
impact
on
human
health
can
be
altered
by
variety
factors
such
as
external
variables,
social
behavior,
age,
nutrition,
genetics.
Gut
microbes’
imbalances
are
related
to
chronic
diseases
including
cancer,
obesity,
digestive
disorders.
Globally,
recent
findings
show
that
intestinal
have
significant
role
in
the
formation
cardiovascular
disease
(CVD),
which
still
primary
cause
fatalities.
Atherosclerosis,
hypertension,
diabetes,
inflammation,
some
inherited
variables
all
risk
variables.
However,
studies
found
correlations
between
metabolism,
flora,
dietary
intake.
Variations
diversity
changes
their
activity
thought
influence
CVD
etiology.
Furthermore,
microbiota
acts
an
endocrine
organ,
producing
bioactive
metabolites
TMA
(trimethylamine)/TMAO
(trimethylamine
N-oxide),
SCFA
(short-chain
fatty
acids),
bile
acids,
substantial
wellness
multiple
mechanisms.
purpose
this
overview
compile
current
evidence
highlighting
intricate
links
microbiota,
metabolites,
development
CVD.
It
focuses
how
dysbiosis
promotes
heart
failure,
atherosclerosis.
This
review
explores
normal
physiology
potential
techniques
targeting
bacteria
treatment
using
various
microbial
metabolites.
also
examines
significance
treatment,
supplements,
prebiotics,
probiotics,
antibiotic
therapies,
fecal
transplantation,
innovative
approach
management
As
result,
metabolic
pathways
become
increasingly
attractive
targets
intervention.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(6), P. 789 - 789
Published: March 10, 2024
Recent
research
exploring
the
relationship
between
gut
and
brain
suggests
that
condition
of
microbiota
can
influence
cognitive
health.
A
well-balanced
may
help
reduce
inflammation,
which
is
linked
to
neurodegenerative
conditions.
Prebiotics,
probiotics,
symbiotics
are
nutritional
supplements
functional
food
components
associated
with
gastrointestinal
well-being.
The
bidirectional
communication
gut–brain
axis
essential
for
maintaining
homeostasis,
pre-,
pro-,
potentially
affecting
various
functions
such
as
attention,
perception,
memory.
Numerous
studies
have
consistently
shown
incorporating
into
a
healthy
diet
lead
improvements
in
mood.
Maintaining
support
optimal
function,
crucial
disease
prevention
our
fast-paced,
Westernized
society.
Our
results
indicate
benefits
older
individuals
probiotic
supplementation
but
not
who
good
adequate
levels
physical
activity.
Additionally,
it
appears
there
patients
mild
impairment
Alzheimer’s
disease,
while
mixed
seem
arise
younger
healthier
individuals.
However,
important
acknowledge
individual
responses
vary,
use
these
dietary
should
be
tailored
each
individual’s
unique
health
circumstances
needs.
Diabetes Obesity and Metabolism,
Journal Year:
2024,
Volume and Issue:
26(9), P. 3998 - 4010
Published: July 3, 2024
Abstract
Aim
Our
study
aims
to
provide
an
updated
estimate
of
age‐
and
sex‐specific
deaths
disability‐adjusted
life
years
(DALYs)
associated
with
high
body
mass
index
(BMI)
from
1990
2019
at
the
global,
regional
national
levels,
forecast
global
burden
disease
attributed
BMI
2020
2035.
Methods
We
used
data
for
number
deaths,
DALYs,
age‐standardized
rate
(per
100
000
population),
percentage
change
population
attributable
fraction
Global
Burden
Disease
Study
(GBD
2019)
examine
BMI.
further
applied
autoregressive
integrated
moving
average
(ARIMA)
model
predict
period
2020‐2035.
Results
From
2019,
DALYs
increased
by
148%
155.86%
men,
111.67%
121.78%
women,
respectively.
In
directly
accounted
8.52%
[95%
uncertainty
intervals
(UI)
0.05,
0.12]
all‐cause
5.89%
(95%
UI
0.04,
0.08)
DALYs.
The
highest
death
rates
were
observed
in
men
aged
65‐69
women
75‐79.
DALY
age
group
60‐64
both
sexes.
Central
Asia
region
[163.15
107.72,
223.58)
per
people]
Oceania
[4643.33
2835.66,
6902.6)
people],
Fiji
[319.08
213.77,
444.96)
Kiribati
[10
000.58
6266.55,
14159.2)
had
rates,
BMI‐related
middle‐high
socio‐demographic
quintile
middle
quintile.
are
projected
increase
sexes
rise
62.79
64.31
people,
while
1946
2099.54
people.
Conclusions
High
BMIs
significantly
contribute
burden.
2035
highlights
critical
need
address
impact
obesity
on
public
health.
provides
policymakers
up‐to‐date
comprehensive
information.
npj Digital Medicine,
Journal Year:
2024,
Volume and Issue:
7(1)
Published: July 5, 2024
The
aim
of
this
meta-meta-analysis
was
to
systematically
review
randomised
controlled
trial
(RCT)
evidence
examining
the
effectiveness
e-
and
m-Health
interventions
designed
improve
physical
activity,
sedentary
behaviour,
healthy
eating
sleep.
Nine
electronic
databases
were
searched
for
eligible
studies
published
from
inception
1
June
2023.
Systematic
reviews
with
meta-analyses
RCTs
that
evaluate
sleep
in
any
adult
population
included.
Forty-seven
included,
comprising
507
206,873
participants.
Interventions
involved
mobile
apps,
web-based
SMS
interventions,
14
focused
on
3
diet,
4
26
evaluating
multiple
behaviours.
Meta-meta-analyses
showed
resulted
improvements
steps/day
(mean
difference,
MD
=
1329
[95%
CI
593.9,
2065.7]
steps/day),
moderate-to-vigorous
activity
(MD
55.1
13.8,
96.4]
min/week),
total
44.8
21.6,
67.9]
behaviour
-426.3
-850.2,
-2.3]
fruit
vegetable
consumption
0.57
0.11,
1.02]
servings/day),
energy
intake
-102.9
kcals/day),
saturated
fat
-5.5
grams/day),
bodyweight
-1.89
-2.42,
-1.36]
kg).
Analyses
based
standardised
mean
differences
(SMD)
quality
(SMD
0.56,
95%
0.40,
0.72)
insomnia
severity
-0.90,
-1.14,
-0.65).
Most
subgroup
analyses
not
significant,
suggesting
a
variety
are
effective
across
diverse
age
health
populations.
These
offer
scalable
accessible
approaches
help
individuals
adopt
sustain
healthier
behaviours,
implications
broader
public
healthcare
challenges.
Arquivos Brasileiros de Cardiologia,
Journal Year:
2024,
Volume and Issue:
121(2)
Published: Feb. 1, 2024
SOBRE
ESTE
DOCUMENTO
A
publicação
Estatística
Cardiovascular
–
Brasil
tem
por
objetivo
fornecer
uma
compilação
anual
dos
dados
e
das
pesquisas
sobre
a
epidemiologia
DCV
no
Brasil.
Este
documento
congrega
as
estatísticas
oficiais
do
Ministério
da
Saúde
outras
entidades
governamentais
ao
lado
de
projeto
GBD,
coordenado
pelo
IHME
Universidade
Washington.
Além
disso,
incorpora
derivados
várias
fontes
estudos
científicos,
inclusive
coortes
registros,
relacionados
às
fatores
risco
[...]
Journal of Activity Sedentary and Sleep Behaviors,
Journal Year:
2024,
Volume and Issue:
3(1)
Published: March 14, 2024
Abstract
Researchers
have
adopted
a
variety
of
analytical
techniques
to
examine
the
collective
influence
24-h
movement
behaviors
(i.e.,
physical
activity,
sedentary
behaviors,
sleep)
on
mental
health,
but
efforts
synthesize
this
growing
body
literature
been
limited
studies
children
and
youth.
This
systematic
review
investigated
how
combinations
relate
indicators
ill-being
well-being
across
lifespan.
A
search
MEDLINE,
PsycINFO,
Embase,
SPORTDiscus
was
conducted.
Studies
were
included
if
they
reported
all
three
behaviors;
an
indicator
or
well-being;
published
in
English
after
January
2009.
Samples
both
clinical
non-clinical
populations
included.
total
73
(
n
=
58
cross-sectional;
15
longitudinal)
met
our
inclusion
criteria,
which
47
children/youth
26
adults.
Seven
approaches
used:
guideline
adherence
(total
specific
combinations),
compositions,
isotemporal
substitution,
profile/cluster
analyses,
Goldilocks
method
rest-activity
rhythmicity.
More
associations
for
127
children/youth;
53
adults)
than
54
adults).
Across
lifespan,
favorable
benefits
most
consistently
observed
when
components
guidelines
met.
Movement
compositions
more
often
associated
with
health
youth
Beneficial
behavior
replaced
sleep
activity.
Other
analytic
indicated
that
engaging
healthier
consistent
patterns
(emphasizing
adequate
sleep,
maximizing
minimizing
behaviors)
better
health.
Favorable
less
longitudinal
studies.
Collectively,
these
findings
provide
further
support
adopting
integrative
whole
day
approach
promote
prevent
manage
over
status
quo
focusing
isolation.
literature,
however,
is
still
emerging—for
adults
particular—and
work
required
make
stronger
inferences.
World Journal of Gastrointestinal Oncology,
Journal Year:
2022,
Volume and Issue:
14(1), P. 230 - 241
Published: Jan. 10, 2022
Early-onset
colorectal
cancer
(EOCRC)
has
seen
an
alarming
rise
worldwide
over
the
past
two
decades.
The
reason
for
this
global
trend
is
poorly
understood.
EOCRC
appears
to
have
its
own
unique
clinical
and
molecular
features
when
compared
with
late-onset
cancer.
Younger
patients
appear
more
distal
or
rectal
disease,
a
advanced
stage
of
disease
at
presentation,
unfavorable
histological
features.
Identifying
risk
factors
first
step
in
mitigating
rising
burden
disease.
Here
we
summarize
several
noteworthy
biological
environmental
exposures
that
are
postulated
be
responsible
culprits.
This
can
hopefully
translate
practice
development
better
stratification
tool
identifying
high-risk
individuals
early
screening,
areas
needed
further
research
curb
trend.