Nano Today, Год журнала: 2025, Номер 63, С. 102758 - 102758
Опубликована: Апрель 14, 2025
Язык: Английский
Carbohydrate Polymers, Год журнала: 2024, Номер 331, С. 121873 - 121873
Опубликована: Янв. 30, 2024
Язык: Английский
Процитировано
37
eScience, Год журнала: 2024, Номер unknown, С. 100292 - 100292
Опубликована: Июнь 1, 2024
Developing advanced nanocomposite phase change materials (PCMs) integrating zero-energy thermal management, microwave absorption, photothermal therapy and electrical signal detection can promote the leapfrog development of flexible wearable electronic devices. For this goal, we propose a multidimensional collaborative strategy combining two-dimensional (2D) MXene nanosheets with metal-organic framework-derived one-dimensional (1D) carbon nanotubes (CNTs) zero-dimensional (0D) metal nanoparticles. After encapsulating paraffin wax (PW) in three-dimensional (3D) networked MXene/CoNi-C, resulting composite PCMs exhibit excellent energy storage capacity long-term thermally reliable stability. Benefiting from synergistically enhanced effects CNTs, Co/Ni nanoparticles MXene, PW@MXene/CoNi-C capture photons efficiently transfer phonons quickly, yielding an ultrahigh conversion efficiency 97.5%. Additionally, high absorption minimum reflection loss −49.3 dB at 8.03 GHz heat-related application scenarios. More attractively, corresponding film simultaneously achieve management electromagnetic shielding devices, as well for individuals. This functional integration design provides important reference developing multifunctional
Язык: Английский
Процитировано
23
ACS Nano, Год журнала: 2024, Номер 18(5), С. 4089 - 4103
Опубликована: Янв. 25, 2024
To meet the requirements of biomedical applications in antibacterial realm, it is great importance to explore nano-antibiotics for wound disinfection that can prevent development drug resistance and possess outstanding biocompatibility. Therefore, we attempted synthesize an atomically dispersed ion (Fe) on phenolic carbon quantum dots (CQDs) combined with organic photothermal agent (PTA) (Fe@SAC CQDs/PTA) via a hydrothermal/ultrasound method. Fe@SAC CQDs adequately exerted peroxidase-like activity while PTA presented excellent conversion capability, which provided enormous potential applications. Based our work, CQDs/PTA exhibited eradication Escherichia coli (>99% inactivation efficiency) Staphylococcus aureus based synergistic chemodynamic therapy (CDT) (PTT). Moreover, vitro experiments demonstrated could inhibit microbial growth promote bacterial biofilm destruction. In vivo suggested CQDs/PTA-mediated CDT PTT promotion recovery effects. This work indicated serve as broad-spectrum antimicrobial nano-antibiotic, was simultaneously beneficial eradication, disinfection, healing.
Язык: Английский
Процитировано
22
ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(26), С. 33205 - 33222
Опубликована: Июнь 25, 2024
In diabetic patients with skin injuries, bacterial proliferation, accumulation of reactive oxygen species (ROS) in the tissues, and impaired angiogenesis make wound healing difficult. Therefore, eliminating bacteria, removing ROS, promoting are necessary for treating acute wounds. this study, benefiting from ability polyphenols to form a metal-phenolic network (MPN) metal ions, TA-Eu MPN nanoparticles (TM NPs) were synthesized. The prepared photothermal agent CuS NPs TM then loaded onto supporting base needle tips PVA/HA (PH) microneedles, respectively, obtain PH/CuS/TM microneedles. Antibacterial experiments showed that microneedles could remove bacteria by effect. vitro effectively scavenge inhibit macrophage polarization M1 type, induce M2 type as well have promote vascular endothelial cell migration angiogenesis. Furthermore, vivo accelerated inhibiting pro-inflammatory cytokines rat model. efficient antibacterial, ROS scavenging, anti-inflammatory, immunomodulatory, angiogenic abilities hold promise dressings
Язык: Английский
Процитировано
15
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 266, С. 131277 - 131277
Опубликована: Март 31, 2024
Bacteria-infected wound healing has attracted widespread attention in biomedical engineering. Wound dressing is a potential strategy for repairing infectious wounds. However, the development of with appropriate physiochemical, antibacterial, and hemostatic properties, remains challenging. Hence, there motivation to develop new synthetic dressings improve bacteria-infected healing. Here, we fabricate biocompatible sponge through covalent crosslinking collagen (Col), quaternized chitosan (QCS), graphene oxide (GO). The resulting Col-QCS-GO shows an elastic modulus 1.93-fold higher than Col due enhanced degree by GO incorporation. Moreover, fabricated favorable porosity (84.30 ± 3.12 %), water absorption/retention (2658.0 113.4 %/1114.0 65.7 hemostasis capacities (blood loss <50.0 mg). Furthermore, antibacterial property under near-infrared (NIR) irradiation significantly (the inhibition rates are 99.9 % S. aureus E. coli) inherent properties QCS photothermal capabilities GO. Finally, Col-QCS-GO+NIR exhibits lowest percentage area (9.05 1.42 %) at day 14 compared control group (31.61 1.76 %). This study provides insights developing innovative sponges
Язык: Английский
Процитировано
13
Small, Год журнала: 2024, Номер 20(45)
Опубликована: Июль 25, 2024
Abstract Diabetic wounds pose a persistent challenge due to their slow healing nature, primarily caused by bacterial infection and excessive reactive oxygen species (ROS)‐induced inflammation. In this study, carbon dots with synergistic antibacterial antioxidant properties, referred as AA‐CDs, are developed specifically for diabetic wound using straightforward solvothermal method. By utilizing cost‐effective precursors like citric acid ascorbic acid, AA‐CDs engineered possess tailored functions of photothermal sterilization ROS scavenging. The resulting demonstrats broad‐spectrum activity, particularly against multidrug‐resistant strains, along efficient scavenging both in solution within cells. Additionally, exhibits protective effect oxidative stress‐induced damage. Notably, high conversion efficiency (41.18%), displays heat‐enhanced performance, providing not only augmented but also additional protection stress, yielding true “1 + 1 > 2” effect. To facilitate use vivo, incorporated into thermally responsive hydrogel, which evident anti‐inflammatory properties modulating inflammatory factors significantly promots the wounds. This study underscores value integrated platforms highlights potential versatile CDs promising therapeutic agents biomedical applications.
Язык: Английский
Процитировано
11
Advanced Functional Materials, Год журнала: 2024, Номер 34(34)
Опубликована: Апрель 1, 2024
Abstract Electron spinning polarization has garnered increased attention for its potential to enhance device properties. However, application in life health, specifically anti‐infection and tissue repair, remains under‐explored. In this study, a ferromagnetic heterojunction CF (Fe 3 O 4 /TiO 2 ) is constructed with spin‐polarized electrons, demonstrating efficient antibiosis performance ultrasound (US) assistance. The antibacterial mechanism elucidated as follows: metallic states of Fe induce an asymmetric distribution the electron spin state TiO , increasing density electrons near Fermi level CF. Under US treatment, built‐in electric field synergistically suppress recombination sono‐activated carriers, promoting reactive oxygen species (ROS) production. Simultaneously, bacterial membrane influenced by micromagnetic induced causing severe disturbance respiratory chain. combined damage from ROS disturbed chain results death. Fortunately, built activates specific mechanosensitive ion channels, including TREK1, Piezo1, related pathways, enhancing osteoblast differentiation. Sonotherapy using exhibits excellent therapeutic effect treating osteomyelitis. This study provides novel insights into manipulating applications health.
Язык: Английский
Процитировано
9
Chemical Engineering Journal, Год журнала: 2024, Номер 500, С. 157299 - 157299
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
8
Small, Год журнала: 2025, Номер unknown
Опубликована: Янв. 10, 2025
Abstract Diabetic ulcers (DUs) are characterized by a microenvironment with high oxidative stress, blood glucose levels, and recalcitrant bacterial infections. This is accompanied long‐term suppression of endogenous antioxidant systems, which makes their clinical management extremely challenging. To address this issue, hybridized novel gold‐palladium (AuPd) nanoshell the injectable/injectable hydrogel system UiO/AuPd shells /BNN6/PEG@Gel (UAPsBP@Gel) developed. The capable acting as nitric oxide (NO) reactor utilizing synergistic therapy that harnesses NIR‐II light‐triggered photothermal effects controlled release NO gas for treatment to eradicate biofilm infections at different depths. AuPd nanoshells exhibits superoxide dismutase (SOD)‐, oxidase (GOx)‐, catalase (CAT)‐like activities, enabling self‐cascade process scavenging both reactive oxygen species (ROS) glucose. activity reshapes DUs microenvironment, switches on Nrf2/HO‐1 pathway inhibits NF‐κB pathway, promotes macrophage polarization toward anti‐inflammatory M2 phenotype, reduces resulting in efficient immunomodulation. In vitro / vivo results demonstrate UAPsBP@Gel can multifacetedly enhance epithelial rejuvenation through wound hemostasis, pro‐cellular migration vascularization. These highlight programmed therapeutic based UBAPsP@Gel tailored stages infected meet complex needs.
Язык: Английский
Процитировано
1
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 159738 - 159738
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1