The
virtual
hand
interaction
technique
is
one
of
the
most
common
techniques
used
in
reality
(VR)
systems.
A
VR
application
can
be
designed
with
different
visualization
styles,
which
might
impact
motor
dexterity.
In
this
paper,
we
aim
to
investigate
effects
three
styles
—
transparent,
opaque,
and
invisible
on
participants'
performance
through
a
VR-based
Purdue
Pegboard
Test
(PPT).
total
24
participants
were
recruited
instructed
place
pegs
board
as
quickly
accurately
possible.
results
indicated
that
using
significantly
increased
number
task
repetitions
completed
compared
opaque
visualization.
However,
no
significant
difference
was
observed
preference
for
styles.
These
findings
suggest
an
may
enhance
PPT,
potentially
indicating
advantages
less
obstructive
style.
We
hope
our
guide
developers,
researchers,
practitioners
when
designing
novel
techniques.
Frontiers in Aging Neuroscience,
Год журнала:
2024,
Номер
16
Опубликована: Май 15, 2024
Age-related
motor
impairments
often
cause
caregiver
dependency
or
even
hospitalization.
However,
comprehensive
investigations
of
the
different
abilities
and
changes
thereof
across
adult
lifespan
remain
sparse.
We,
therefore,
extensively
assessed
essential
basic
complex
functions
in
444
healthy
adults
covering
a
wide
age
range
(range
21
to
88
years).
Basic
functions,
here
defined
as
simple
isolated
single
repetitive
movements
one
direction,
were
by
means
maximum
grip
strength
(GS)
finger-tapping
frequency
(FTF).
Complex
comprising
composite
sequential
involving
both
proximal
distal
joints/muscle
groups,
evaluated
with
Action
Research
Arm
Test
(ARAT),
Jebsen-Taylor
Hand
Function
(JTT),
Purdue
Pegboard
Test.
Men
achieved
higher
scores
than
women
concerning
GS
FTF,
whereas
stacked
more
pins
per
time
men
during
There
was
no
significant
sex
effect
regarding
JTT.
We
observed
but
task-specific
reduction
performance
lifespan.
Linear
regression
analyses
significantly
predicted
participants'
ages
based
on
(
Frontiers in Neuroscience,
Год журнала:
2020,
Номер
14
Опубликована: Янв. 29, 2020
To
develop
a
real-time
neurofeedback
system
from
the
anterior
prefrontal
cortex
(aPFC)
using
functional
near-infrared
spectroscopy
(fNIRS)
for
motor
rehabilitation,
we
investigated
effects
of
imagery
training
with
aPFC
on
hand
dexterity
and
cerebral
hemodynamic
activity
during
rehabilitation
task.
Thirty-one
right-handed
healthy
subjects
participated
in
this
study.
They
received
6
times
2
weeks
under
fNIRS
aPFC,
which
they
were
instructed
to
increase
activity.
The
real
group
(n=16)
shown
signals
whereas
sham
(n=15)
irrelevant
randomized
training.
Before
after
training,
was
assessed
by
task,
also
measured.
results
indicated
that
increased
performance
improvement
rates
task
when
compared
group.
Improvement
mean
across
positively
correlated
During
left
somatosensory
motor-related
areas
[premotor
area
(PM),
primary
(M1),
(S1)]
group,
supplementary
This
increases
last
two
days
Furthermore,
M1
suggest
might
shape
improve
dexterity.
These
findings
further
be
useful
patients
disability.
Frontiers in Physiology,
Год журнала:
2020,
Номер
11
Опубликована: Март 27, 2020
Coordinated
bimanual
control
depends
on
information
processing
in
different
intra-
and
interhemispheric
networks
that
differ
with
respect
to
task
symmetry
laterality
of
execution.
Aging
age-related
cognitive
impairments,
but
also
sex
can
have
detrimental
effects
connectivity
these
networks.
We
therefore
expected
age,
function
force
coordination.
furthermore
depend
the
characteristics
(i.e.,
difficulty
symmetry).
162
right
handed
participants
(19
younger
adults
[YA],
21-30
years,
9
females;
52
cognitively
healthy
older
[HOA],
80-91
32
91
mild
impairments
[MCI]
37
females)
performed
isometric
tasks
required
following
constant
or
alternating
(cyclic
sine-wave)
targets
varied
symmetry,
i.e.,
(i)
symmetric,
asymmetric
[with
left
(ii)
vice
versa
(iii)],
(iv)
in-
(v)
antiphase
(both
hands
0°
180°
relative
phase,
respectively).
analyzed
general
performance
(time
target),
coordination
as
coupling
between
(linear
correlation
coefficient)
structure
variability
complexity
measured
through
detrended
fluctuation
analysis).
Performance
strongly
depended
executing
hand,
better
symmetric
when
hand
produced
a
an
force.
HOA
MCI,
compared
YA,
showed
poorer
target)
reduced
tasks.
Furthermore,
both
groups
OA
displayed
less
complex
production
tasks,
marker
control.
In
addition,
we
found
strong
females
displaying
during
variably
production.
Results
this
study
revealed
Effects
possibly
due
requirements
processing.
So
far,
no
clear
relationship
behavioral
markers
decline
(compared
aging),
making
further
investigation
necessary.
Geriatrics,
Год журнала:
2023,
Номер
8(2), С. 31 - 31
Опубликована: Фев. 27, 2023
The
relationship
between
hand
dexterity
and
inhibitory
control
across
the
lifespan
is
underexplored.
In
this
pilot
study,
we
examined
using
a
modified
Simon
task.
During
task,
participants
were
presented
with
right-
left-pointing
arrows
located
either
on
right
or
left
parts
of
screen.
congruent
trials,
arrow
location
direction
matched.
incongruent
they
mismatched,
thus
creating
cognitive
interference.
50%
presentation
was
accompanied
by
task-irrelevant
but
environmentally
meaningful
sound
that
created
perceptual
Hand
measured
9-hole
peg
test.
Significantly
faster
reaction
time
(RT)
task
(p
<
0.001)
observed
in
younger
adults,
trials
concurrent
stimuli,
trials.
Older
adults
who
reported
recent
falls
had
greater
difficulty
resolving
interference
than
older
without
falls.
significantly
moderated
effect
RT,
only
group
individuals.
Interestingly,
individuals
reduced
benefited
from
sounds
more
those
better
dexterity.
Our
findings
suggest
may
increase
alertness
enhance
stimulus
perception
recognition,
improving
motor
performance
Pharmaceutics,
Год журнала:
2023,
Номер
15(4), С. 1315 - 1315
Опубликована: Апрель 21, 2023
Swallowability,
visual
perception,
and
any
handling
to
be
conducted
prior
use
are
all
influence
factors
on
the
acceptability
of
an
oral
dosage
form
by
patient.
Knowing
preferences
older
adults,
as
major
group
medication
end
users,
is
needed
for
patient-centric
drug
development.
This
study
aimed
at
evaluating
ability
adults
handle
tablets
well
assess
anticipated
swallowability
tablets,
capsules,
mini
based
perception.
The
randomized
intervention
included
52
(65
94
years)
younger
(19
36
years).
Within
tested
ranging
from
125
mg
up
1000
in
weight
being
different
shapes,
was
not
seen
limiting
factor
decision
appropriate
tablet
size.
However,
smallest
sized
were
rated
worst.
According
limit
acceptable
size
reached
around
250
adults.
For
this
shifted
higher
weights
dependent
shape.
Differences
with
respect
shapes
most
pronounced
500
750
weight,
independent
age
category.
Capsules
performed
worse
compared
while
appeared
a
possible
alternative
weight.
deglutition
part
study,
capabilities
same
populations
assessed
have
been
reported
previously.
Comparing
present
results
swallowing
it
shows
adults’
clear
self-underestimation
their
swallow
age.
European Journal of Pharmaceutical Sciences,
Год журнала:
2023,
Номер
187, С. 106453 - 106453
Опубликована: Май 4, 2023
Older
adults
are
the
main
users
of
medicine
and
due
to
common
multimorbidity
they
often
confronted
with
a
complex
medication
management.
This
review
article
provides
brief
overview
on
aspects
management,
i.e.,
maintaining
stock
required
medicine,
understanding
following
instructions
for
use,
coping
primary
secondary
packaging,
as
well
preparation
prior
use.
However,
focus
is
drug
intake
itself
an
current
real
life
dosing
conditions
in
older
geriatric
patients.
It
elaborates
acceptability
dosage
forms,
particular
solid
oral
forms
represent
majority
taken
by
this
patient
population.
An
improved
needs
patients,
their
various
circumstances
under
which
manage
medications
will
allow
design
more
patient-centric
products.
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 5, 2024
Abstract
Age-related
motor
impairments
often
cause
caregiver
dependency
or
even
hospitalization.
However,
comprehensive
investigations
of
the
different
abilities
and
changes
thereof
across
adult
lifespan
remain
sparse.
We,
therefore,
extensively
assessed
essential
basic
complex
functions
in
444
healthy
adults
covering
a
wide
age
range
(range
21
to
88
years).
Basic
functions,
here
defined
as
simple
isolated
single
repetitive
movements
one
direction,
were
by
means
maximum
grip
strength
(GS)
finger-tapping
frequency
(FTF).
Complex
comprising
composite
sequential
involving
both
proximal
distal
joints/muscle
groups,
evaluated
with
Action
Research
Arm
Test
(ARAT),
Jebsen-Taylor
Hand
Function
(JTT),
Purdue
Pegboard
Test.
Men
achieved
higher
scores
than
women
concerning
GS
FTF,
whereas
stacked
more
pins
per
time
men
during
There
was
no
significant
sex
effect
regarding
JTT.
We
observed
but
task-specific
reduction
performance
lifespan.
Linear
regression
analyses
significantly
predicted
participants’
ages
based
on
(R
2
=
.502).
Of
note,
ratio
between
left-
right-hand
remained
stable
for
all
tests.
Principal
Component
Analysis
(PCA)
revealed
three
components
tests
that
represented
dexterity,
force,
speed.
These
consistently
present
young
(21
–
40
years),
middle-aged
(41
60
older
(61
years)
adults,
well
men.
Based
,
K-means
clustering
analysis
differentiated
high-
low-performing
participants
life
span.
The
rich
data
set
age-
sex-dependent
functions.
Notably,
assessment
allowed
generating
robust
Our
may
serve
reference
future
studies
subjects
patients
deficits.
Moreover,
these
findings
emphasize
importance
comprehensively
assessing
including
speed,
characterize
human
their
age-related
decline.
