Biomaterials, Год журнала: 2024, Номер 309, С. 122620 - 122620
Опубликована: Май 22, 2024
Язык: Английский
Coordination Chemistry Reviews, Год журнала: 2023, Номер 500, С. 215532 - 215532
Опубликована: Ноя. 10, 2023
Язык: Английский
Процитировано
26
Coordination Chemistry Reviews, Год журнала: 2023, Номер 493, С. 215315 - 215315
Опубликована: Июнь 24, 2023
Язык: Английский
Процитировано
24
Journal of Materials Chemistry A, Год журнала: 2024, Номер 12(22), С. 13116 - 13126
Опубликована: Янв. 1, 2024
Superhydrophilic COFs with D–A structure accelerate photocatalytic synthesis of H 2 O using water as a proton supply reservoir.
Язык: Английский
Процитировано
16
Chemical Society Reviews, Год журнала: 2024, Номер 53(17), С. 8847 - 8877
Опубликована: Янв. 1, 2024
Significant advances have been made in materials for biomedical applications, including tissue engineering, bioimaging, cancer treatment,
Язык: Английский
Процитировано
15
ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(36), С. 46988 - 47002
Опубликована: Авг. 27, 2024
Early cancer detection is crucial for effective treatment, but current methods have limitations. Novel biomaterials, such as hydrogels, offer promising alternatives developing biosensors detection. Hydrogels are three-dimensional and cross-linked networks of hydrophilic polymers that properties similar to biological tissues. They can be combined with various achieve high sensitivity, specificity, stability. This review summarizes the recent advances in hydrogel-based detection, their synthesis, applications, challenges. It also discusses implications future directions this emerging field.
Язык: Английский
Процитировано
15
Cancers, Год журнала: 2024, Номер 16(12), С. 2171 - 2171
Опубликована: Июнь 7, 2024
Cancer cells show altered antioxidant defense systems, dysregulated redox signaling, and increased generation of reactive oxygen species (ROS). Targeting cancer through ROS-mediated mechanisms has emerged as a significant therapeutic strategy due to its implications in progression, survival, resistance. Extensive research focused on selective H2O2 for cell killing by employing various strategies such metal-based prodrugs, photodynamic therapy, enzyme-based nano-particle mediated approaches, chemical modulators, combination therapies. Many these H2O2-amplifying approaches have demonstrated promising anticancer effects selectivity preclinical investigations. They selectively induce cytotoxicity while sparing normal cells, sensitize resistant modulate the tumor microenvironment. However, challenges remain achieving selectivity, addressing heterogeneity, ensuring efficient delivery, managing safety toxicity. To address those issues, H2O2-generating agents been combined with other treatments leading optimized This review focuses agents/approaches that kill via H2O2-mediated mechanisms. Different categories compounds generate are summarized, their underlying function elucidated, clinical studies well recent advancements discussed, prospects targeted utility explored. By understanding potential compounds, researchers can pave way development effective personalized treatments.
Язык: Английский
Процитировано
13
Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(33), С. 8048 - 8061
Опубликована: Янв. 1, 2024
Photothermal therapy (PTT) is an important non-invasive cancer treatment method.
Язык: Английский
Процитировано
13
Aggregate, Год журнала: 2024, Номер unknown
Опубликована: Сен. 2, 2024
Abstract Phototheranostics has garnered sustained attention due to its significant potential for revolutionizing conventional cancer treatment strategies. While being one of the most commonly employed strategies constructing phototheranostic systems by engineering integration photosensitizers (PSs) into nanosystems, nano‐PSs face challenges including complexity in preparation process, low delivery efficiency, and toxicity issues. Contrastingly, burgeoning popularity small molecule PSs characterized aggregation‐induced emission (AIE) become evident arena phototheranostics. This preference is underscored their well‐defined structures, adjustable photophysical properties, toxicity. Therefore, acquiring profound insights pioneering strides achievable through a solitary PS with AIE tumor phototheranostics paramount scientific significance. In this review, we will discuss recent progress properties diagnosis phototherapies representative examples, guided ethos “Complexity made easy”. We also look forward future development direction molecules, central objective advancing research focal emphasis on simplicity, expeditiousness, safety.
Язык: Английский
Процитировано
13
Biosensors and Bioelectronics, Год журнала: 2024, Номер 260, С. 116463 - 116463
Опубликована: Июнь 2, 2024
Язык: Английский
Процитировано
12
ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(3), С. 3215 - 3231
Опубликована: Янв. 11, 2024
Biofilm-associated infections (BAIs) have been considered a major threat to public health, which induce persistent and serious complications. The poor penetration of antibacterial agents in biofilm significantly limits the efficiency combating BAIs. Magnetic urchin-like core–shell nanospheres Fe3O4@Bi2S3 were developed for physically destructing inducing bacterial eradication via reactive oxygen species (ROS) generation innate immunity regulation. magnetic with sharp edges exhibited propeller-like rotation destroy under rotating field (RMF). mild hyperthermia improved ROS enhanced eradication. Significantly, nanostructure generated could stimulate macrophage polarization toward M1 phenotype, eradicate bacteria metabolic inactivity state through phagocytosis, thereby promoting recovery implant infection inhibiting recurrence. Thus, design magnetic-driven sharp-shaped nanostructures provided enormous potential infections.
Язык: Английский
Процитировано
11