Chitosan
is
a
promising
naturally
derived
polysaccharide
to
be
used
in
hydrogel
forms
for
pharmaceutical
and
biomedical
applications.
The
multifunctional
chitosan-based
hydrogels
have
attractive
properties
such
as
the
ability
encapsulate,
carry,
release
drug,
biocompatibility,
biodegradability,
non-immunogenicity.
In
this
review,
advanced
functions
of
are
summarized,
with
emphasis
on
fabrications
resultant
reported
literature
from
recent
decade.
progress
applications
drug
delivery,
tissue
engineering,
disease
treatments,
biosensors
reviewed.
Current
challenges
future
development
direction
prospected.
Polymers,
Год журнала:
2023,
Номер
15(15), С. 3150 - 3150
Опубликована: Июль 25, 2023
Chitin,
which
may
be
the
second-most
common
polymer
after
cellulose,
is
raw
material
of
chitosan.
Chitosan
has
been
infused
with
various
plant
extracts
and
subsidiary
polymers
to
improve
its
biological
physiological
properties.
Chitosan's
physicochemical
properties
are
enhanced
by
blending,
making
them
potential
candidates
that
can
utilized
in
multifunctional
areas,
including
food
processing,
nutraceuticals,
quality
monitoring,
packaging,
storage.
Chitosan-based
biomaterials
biocompatible,
biodegradable,
low
toxic,
mucoadhesive,
regulate
chemical
release.
Therefore,
they
used
biomedical
field.
The
present
manuscript
highlights
application
chitosan-based
composites
industries.
Polymers,
Год журнала:
2023,
Номер
15(9), С. 2028 - 2028
Опубликована: Апрель 25, 2023
Polymers
have
been
widely
used
for
the
development
of
drug
delivery
systems
accommodating
regulated
release
therapeutic
agents
in
consistent
doses
over
a
long
period,
cyclic
dosing,
and
adjustable
both
hydrophobic
hydrophilic
drugs.
Nowadays,
polymer
blends
are
increasingly
employed
as
they
generate
more
promising
results
when
compared
to
those
homopolymers.
This
review
article
describes
recent
research
efforts
focusing
on
utilization
chitosan
with
other
polymers
an
attempt
enhance
properties
chitosan.
Furthermore,
various
applications
thoroughly
discussed
herein.
The
literature
from
past
ten
years
was
collected
using
search
engines
such
ScienceDirect,
J-Gate,
Google
Scholar,
PubMed,
data
were
compiled
according
novel
carrier
systems.
Nanocarriers
made
derivatives
positive
surface
charge,
which
allows
control
rate,
duration,
location
body,
can
increase
safety
efficacy
system.
Recently
developed
nanocarriers
shown
be
cost-effective,
efficacious,
prolonged
carriers
that
incorporated
into
suitable
dosage
forms.
Molecules,
Год журнала:
2022,
Номер
28(1), С. 247 - 247
Опубликована: Дек. 28, 2022
In
the
times
of
dynamically
developing
regenerative
medicine,
more
and
attention
is
focused
on
use
natural
polymers.
This
due
to
their
high
biocompatibility
biodegradability
without
production
toxic
compounds,
which
means
that
they
do
not
hurt
humans
environment.
Chitosan
its
derivatives
are
polymers
made
most
often
from
shells
crustaceans
biodegradable
biocompatible.
Some
them
have
antibacterial
or
metal-chelating
properties.
review
article
presents
development
biomaterials
based
chitosan
used
in
such
as
a
dressing
graft
soft
tissues
bones.
Various
examples
preparations
form
gels,
films,
3D
structures
crosslinking
products
with
another
polymer
discussed
herein.
summarizes
latest
advances
medicine
provides
perspectives
future
research
activities.
Hydrogels
are
three-dimensional
networks
with
a
variety
of
structures
and
functions
that
have
remarkable
ability
to
absorb
huge
amounts
water
or
biological
fluids.
They
can
incorporate
active
compounds
release
them
in
controlled
manner.
also
be
designed
sensitive
external
stimuli:
temperature,
pH,
ionic
strength,
electrical
magnetic
stimuli,
specific
molecules,
etc.
Alternative
methods
for
the
development
various
hydrogels
been
outlined
literature
over
time.
Some
toxic
therefore
avoided
when
obtaining
biomaterials,
pharmaceuticals,
therapeutic
products.
Nature
is
permanent
source
inspiration
new
functionalities
more
competitive
materials.
Natural
present
series
physico-chemical
characteristics
suitable
such
as
biocompatibility,
antimicrobial
properties,
biodegradability,
nontoxicity.
Thus,
they
generate
microenvironments
comparable
intracellular
extracellular
matrices
human
body.
This
paper
discusses
main
advantages
presence
biomolecules
(polysaccharides,
proteins,
polypeptides)
hydrogels.
Structural
aspects
induced
by
natural
their
properties
emphasized.
The
most
applications
will
highlighted,
including
drug
delivery,
self-healing
materials
regenerative
medicine,
cell
culture,
wound
dressings,
3D
bioprinting,
foods,
