Опубликована: Янв. 1, 2024
Язык: Английский
Molecules, Год журнала: 2023, Номер 28(10), С. 3993 - 3993
Опубликована: Май 9, 2023
is a relict tree species showing high resistance to adverse biotic and abiotic environmental factors. Its fruits leaves have medicinal value due the presence of flavonoids, terpene trilactones phenolic compounds. However, ginkgo seeds contain toxic allergenic alkylphenols. The publication revises latest research results (mainly from 2018-2022) regarding chemical composition extracts obtained this plant provides information on use or their selected ingredients in medicine food production. A very important section part which review patents concerning
Язык: Английский
Процитировано
43
Plants, Год журнала: 2023, Номер 12(11), С. 2096 - 2096
Опубликована: Май 24, 2023
Cardiac diseases, such as myocardial infarction and heart failure, have become a major clinical problem globally. The accumulating data demonstrate that bioactive compounds with antioxidant anti-inflammatory properties favorable effects on problems. Kaempferol is flavonoid found in various plants; it has demonstrated cardioprotective numerous cardiac injury models. This review aims to collate updated information regarding the of kaempferol injury. improves function by alleviating apoptosis, fibrosis, oxidative stress, inflammation while preserving mitochondrial calcium homeostasis. However, mechanisms action its remain unclear; therefore, elucidating could provide insight into directions for future studies.
Язык: Английский
Процитировано
34
Molecules, Год журнала: 2024, Номер 29(7), С. 1570 - 1570
Опубликована: Март 31, 2024
The formation of new blood vessels, known as angiogenesis, significantly impacts the development multiple types cancer. Consequently, researchers have focused on targeting this process to prevent and treat numerous disorders. However, most existing anti-angiogenic treatments rely synthetic compounds humanized monoclonal antibodies, often expensive or toxic, restricting patient access these therapies. Hence, pursuit discovering new, affordable, less efficient is imperative. Numerous studies propose that natural plant-derived products exhibit sought-after characteristics. objective review delve into properties exhibited by naturally derived flavonoids from plants, along with their underlying molecular mechanisms action. Additionally, we summarize structure, classification, relationship between signaling pathways in plants agents, including main HIF-1α/VEGF/VEGFR2/PI3K/AKT, Wnt/β-catenin, JNK1/STAT3, MAPK/AP-1 pathways. Nonetheless, further research innovative approaches are required enhance bioavailability for clinical application.
Язык: Английский
Процитировано
11
Foods, Год журнала: 2024, Номер 13(15), С. 2441 - 2441
Опубликована: Авг. 2, 2024
Aging is a natural and irreversible process, affecting living organisms by negatively impacting the tissues' cells' morphology functionality consequently being responsible for aging-related diseases. Taking into account actual preoccupations of both consumers researchers, healthy anti-aging alternatives are intensively studied in order to address such concerns. Due their functional features, plant flavonoids can be considered valuable nutraceuticals. This paper highlights possibilities use extracted from various plants potential on skin, brain, heart. Moreover, anticarcinogenic, anti-inflammatory, anti-diabetic properties summarized, along with senescence-associated mechanisms. Both nutraceutical cosmeceutical fields continuously developing originating promising candidates obtain products. Thus, bioactive compounds' extraction subsequent involvement innovative product manufacturing must carefully performed while aware intrinsic extrinsic factors that may affect phytochemicals' structures, bioavailability, health effects.
Язык: Английский
Процитировано
10
Plant Physiology and Biochemistry, Год журнала: 2025, Номер 220, С. 109502 - 109502
Опубликована: Янв. 12, 2025
Язык: Английский
Процитировано
1
Molecules, Год журнала: 2024, Номер 29(5), С. 1128 - 1128
Опубликована: Март 2, 2024
Taxus mairei (Lemée and H.Lév.) S.Y.Hu, indigenous to the southern regions of China, is an evergreen tree belonging genus Taxaceae family. Owing its content various bioactive compounds, it exhibits multiple pharmacological activities has been widely applied in clinical medicine. This article comprehensively discusses current state cultivation, chemical constituents, applications pharmaceutical field, challenges faced by T. mairei. The paper begins detailing ecological distribution mairei, aiming provide in-depth understanding origin cultivation overview. In terms composition, thoroughly summarizes extracts monomeric components unveiling their elucidating mechanisms action based on latest scientific research, as well potential lead compounds new drug development. also addresses such difficulties extracting synthesizing active need for sustainable utilization strategies. summary, a rare species important biodiversity conservation demonstrates significant research application development disease treatment.
Язык: Английский
Процитировано
4
ACS Omega, Год журнала: 2024, Номер 9(16), С. 18634 - 18642
Опубликована: Апрель 10, 2024
is an endangered evergreen conifer mainly found in Northeast Asia. In addition to the well-known taxanes, several active ingredients were detected leaves of
Язык: Английский
Процитировано
4
The American Journal of Chinese Medicine, Год журнала: 2024, Номер 52(03), С. 625 - 666
Опубликована: Янв. 1, 2024
The pathogenesis of Alzheimer's disease (AD), a degenerative the central nervous system, remains unclear. main manifestations AD include cognitive and behavioral disorders, neuropsychiatric symptoms, neuroinflammation, amyloid plaques, neurofibrillary tangles. However, current drugs for once dementia stage has been reached only treat symptoms do not delay progression, research development targeted have bottleneck. Thus, other treatment options are needed. Bioactive ingredients derived from plants promising therapeutic agents. Specifically,
Язык: Английский
Процитировано
4
Journal of Ethnopharmacology, Год журнала: 2025, Номер unknown, С. 119383 - 119383
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142494 - 142494
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0