Advanced Science,
Journal Year:
2021,
Volume and Issue:
9(4)
Published: Dec. 13, 2021
Abstract
The
combination
of
2D
materials
and
optical
biosensors
has
become
a
hot
research
topic
in
recent
years.
Graphene,
transition
metal
dichalcogenides,
black
phosphorus,
MXenes,
other
(metal
oxides
degenerate
semiconductors)
have
unique
properties
play
role
the
detection
different
biomolecules.
Through
modification
materials,
biosensor
advantages
that
traditional
sensors
(such
as
electrical
sensing)
do
not
have,
sensitivity
limit
are
greatly
improved.
Here,
based
on
reviewed.
First,
various
methods
biomolecules,
including
surface
plasmon
resonance
(SPR),
fluorescence
energy
transfer
(FRET),
evanescent
wave
properties,
preparation
integration
strategies
material,
introduced
detail.
Second,
summarized.
Furthermore,
applications
these
biological
imaging,
food
safety,
pollution
prevention/control,
medicine
discussed.
Finally,
future
development
is
prospected.
It
believed
with
their
in‐depth
laboratory,
will
gradually
commercialized
improve
people's
quality
life
many
aspects.
Chemical Reviews,
Journal Year:
2020,
Volume and Issue:
120(4), P. 2288 - 2346
Published: Jan. 23, 2020
As
a
novel
member
of
the
two-dimensional
nanomaterial
family,
mono-
or
few-layer
black
phosphorus
(BP)
with
direct
bandgap
and
high
charge
carrier
mobility
is
promising
in
many
applications
such
as
microelectronic
devices,
photoelectronic
energy
technologies,
catalysis
agents.
Due
to
its
benign
elemental
composition
(phosphorus),
large
surface
area,
electronic/photonic
performances,
chemical/biological
activities,
BP
has
also
demonstrated
great
potential
biomedical
including
biosensing,
photothermal/photodynamic
therapies,
controlled
drug
releases,
antibacterial
uses.
The
nature
BP-bio
interface
comprised
dynamic
contacts
between
nanomaterials
(NMs)
biological
systems,
where
system
interact.
physicochemical
interactions
at
nano-bio
play
critical
role
effects
NMs.
In
this
review,
we
discuss
context
unique
properties
that
may
affect
effects.
Herein,
comprehensively
reviewed
recent
studies
on
biomolecules,
cells,
animals
summarized
various
cellular
responses,
inflammatory/immunological
effects,
well
other
outcomes
depending
own
physical
properties,
exposure
routes,
biodistribution.
addition,
discussed
environmental
behaviors
risks
organisms
BP.
Based
accumulating
knowledge
interfaces,
review
summarizes
safer-by-design
strategies
change
chemical
stability
interactions,
which
are
tuning
better
understanding
activity
interfaces
corresponding
methods
overcome
challenges
would
promote
future
exploration
terms
bringing
new
practical
applications.
Theranostics,
Journal Year:
2019,
Volume and Issue:
10(2), P. 757 - 781
Published: Dec. 6, 2019
The
marked
augment
of
drug-resistance
to
traditional
antibiotics
underlines
the
crying
need
for
novel
replaceable
antibacterials.Research
advances
have
revealed
considerable
sterilization
potential
two-dimension
graphene-based
nanomaterials.Subsequently,
two-dimensional
nanomaterials
beyond
graphene
(2D
NBG)
as
antibacterials
also
demonstrated
their
power
disinfection
due
unique
physicochemical
properties
and
good
biocompatibility.Therefore,
exploration
antibacterial
mechanisms
2D
NBG
is
vital
manipulate
future
applications.Herein,
we
summarize
recent
research
progress
NBG-based
agents,
starting
with
a
detailed
introduction
relevant
mechanisms,
including
direct
contact
destruction,
oxidative
stress,
photo-induced
antibacterial,
control
drug/metallic
ions
releasing,
multi-mode
synergistic
antibacterial.Then,
effect
on
activities
discussed.Additionally,
summary
different
kinds
given,
such
transition-metal
dichalcogenides/oxides,
metal-based
compounds,
nitride-based
nanomaterials,
black
phosphorus,
transition
metal
carbides,
nitrides.Finally,
rationally
analyze
current
challenges
new
perspectives
study
more
effective
agents.This
review
not
only
can
help
researchers
grasp
status
antibacterials,
but
may
catalyze
breakthroughs
in
this
fast-growing
field.
Advanced Functional Materials,
Journal Year:
2019,
Volume and Issue:
29(29)
Published: May 10, 2019
Abstract
Black
phosphorus
nanostructures
(nano‐BPs)
include
BP
nanosheets,
quantum
dots,
and
nanoparticles.
Since
first
being
discovered
in
2014,
nano‐BP
has
become
one
of
the
most
popular
nanomaterials.
Nano‐BP
many
unique
properties,
such
as
excellent
surface
activity,
tunable
bandgap,
high
carrier
mobility,
moderate
on/off
ratio,
biocompatibility,
good
biodegradation,
etc.,
all
which
make
particularly
attractive
biomedicine
biosensing.
This
review
article
comprehensively
summarizes
recent
advances
synthesis,
functionalization,
biomedicine,
biosensing
applications
nano‐BP.
Different
methods
are
introduced,
mechanical
cleavage,
liquid‐phase
ultrasonic
exfoliation,
electrochemical
solvothermal
treatment,
acoustic‐microfluidic
stripping,
for
making
Then
two
strategies
emphasized
to
enhance
ambient
stability
nano‐BP,
namely
physical
encapsulation
chemical
modification.
Next,
how
develop
advanced
imaging
agents,
nanocarriers,
nanomedicine
bioimaging
(fluorescence
imaging,
thermal
photoacoustic
imaging)
disease
treatment
(phototherapy
photo/chemical/immune
synergistic
therapy)
is
demonstrated.
The
on
including
biosensor,
fluorescence
chemiluminescence
electrogenerated
colorimetric
biosensor.
Finally,
current
challenges
future
perspectives
bioapplications
discussed.
Advanced Functional Materials,
Journal Year:
2021,
Volume and Issue:
31(32)
Published: June 10, 2021
Abstract
Non‐invasive
cancer
photothermal
therapy
(PTT)
is
a
promising
replacement
for
traditional
treatments.
The
second
near‐infrared
region
induced
PTT
(NIR‐II
PTT,
1000–1500
nm)
with
less
energy
dissipation
has
been
developed
deeper‐seated
tumor
treatment
in
recent
years
compared
the
first
light
(750–1000
nm).
In
addition,
use
of
emerging
inorganic
2D
nanomaterials
as
agents
(PTAs)
further
enhanced
efficiency
due
to
their
intrinsic
properties.
NIR‐II
stimulated
becoming
hot
topic
both
academic
and
clinical
fields.
This
review
summarizes
categories,
structures,
conversion
properties
time.
synergistic
strategies
responsive
combined
other
approaches
including
chemotherapy,
chemodynamic
therapy,
photodynamic
radiotherapy
are
summarized.
future
challenges
perspectives
on
these
systems
construction
discussed.
Advanced Functional Materials,
Journal Year:
2020,
Volume and Issue:
30(30)
Published: April 30, 2020
Abstract
Considering
the
ever‐growing
climatic
degeneration,
sustainable
and
renewable
energy
sources
are
needed
to
be
effectively
integrated
into
grid
through
large‐scale
electrochemical
storage
conversion
(EESC)
technologies.
With
regard
their
competent
benefit
in
cost
supply
of
resource,
room‐temperature
sodium‐ion
batteries
(SIBs)
have
shown
great
promise
EESC,
triumphing
over
other
battery
systems
on
market.
As
one
most
fascinating
cathode
materials
due
simple
synthesis
process,
large
specific
capacity,
high
ionic
conductivity,
Na‐based
layered
transition
metal
oxide
cathodes
commonly
suffer
from
sluggish
kinetics,
multiphase
evolution,
poor
air
stability,
insufficient
comprehensive
performance,
restricting
commercialization
application.
Here,
this
review
summarizes
recent
advances
for
SIBs
different
optimal
structure
modulation
technologies,
with
an
emphasis
placed
strategies
boost
Na
+
kinetics
reduce
irreversible
phase
as
well
enhance
store
stability.
Meanwhile,
a
thorough
in‐depth
systematical
investigation
structure–function–property
relationship
is
also
discussed,
challenges
opportunities
practical
application
electrode
sketched.
The
insights
brought
forward
can
considered
guide
next‐generation
EESC.
Smart Materials in Medicine,
Journal Year:
2020,
Volume and Issue:
1, P. 32 - 47
Published: Jan. 1, 2020
Tumor
is
a
severe
disease
that
affects
human
health.
In
addition
to
surgical
treatment
and
radiotherapy,
applying
therapeutic
agents
can
kill
the
tumor
directly
or
regulate
immune
systems
one
of
most
common
treatments.
The
current
problems
these
are
lacking
selective
targeting
causing
unfavorable
side
effects.
order
solve
develop
more
effective
medicines,
nano-carriers
employed
fabricate
smart
drug
delivery
systems.
recent
years,
novel
inorganic
nano-materials,
like
mesoporous
silica
nanoparticles,
gold
graphene
oxide
black
phosphorus,
have
shown
talent
in
loading
capacity,
stability,
biocompatibility,
which
becoming
candidates
for
nano-carriers.
This
review
not
only
provides
comprehensive
summary
on
mechanisms
nano-carrier
based
but
also
summarizes
their
synthesis,
applications,
challenges
future
possibilities.
Nano Letters,
Journal Year:
2020,
Volume and Issue:
20(5), P. 3943 - 3955
Published: April 3, 2020
Black
phosphorus
(BP)-based
nanomaterials
have
distinguished
advantages
and
potential
applications
in
various
biomedical
fields.
However,
their
biological
effects
physiological
systems
remain
largely
unexplored.
Here,
we
systematically
revealed
a
reactive
oxygen
species
(ROS)-mediated
mechanism
for
the
selective
killing
of
cancer
cells
by
BP-based
nanosheets.
The
treatment
with
materials
can
induce
higher
levels
ROS
than
normal
cells,
leading
to
significant
changes
cytoskeleton,
cell
cycle
arrest,
DNA
damage,
apoptosis
tumor
lines.
We
that
decreased
superoxide
dismutase
activity
lipid
peroxides
could
be
an
essential
selectively
generation
induced
nanosheets
cells.
In
addition,
effect
only
occurred
within
certain
dosage
range
(named
"SK
range"
this
study).
Once
exceeding
SK
range,
also
high
production
tissues,
detectable
damage
pathological
characteristics
organs
raising
safety
concerns.
These
findings
not
shed
light
on
new
but
provide
deep
insights
into
safe
use
therapies.
