International Journal of Molecular Sciences,
Journal Year:
2021,
Volume and Issue:
22(15), P. 7837 - 7837
Published: July 22, 2021
The
musculoskeletal
system
is
a
vital
body
that
protects
internal
organs,
supports
locomotion,
and
maintains
homeostatic
function.
Unfortunately,
disorders
are
the
leading
cause
of
disability
worldwide.
Although
implant
surgeries
using
autografts,
allografts,
xenografts
have
been
conducted,
several
adverse
effects,
including
donor
site
morbidity
immunoreaction,
exist.
To
overcome
these
limitations,
various
biomedical
engineering
approaches
proposed
based
on
an
understanding
complexity
human
tissue.
In
this
review,
edge
tissue
3D
bioprinting
technology
tissue-derived
decellularized
extracellular
matrix
bioink
described.
particular,
studies
in
vivo
regeneration
vitro
modeling
focused
on.
Lastly,
current
breakthroughs,
future
perspectives
iScience,
Journal Year:
2023,
Volume and Issue:
26(2), P. 106039 - 106039
Published: Jan. 25, 2023
Three-dimensional
(3D)
bioprinting
has
emerged
as
a
class
of
promising
techniques
in
biomedical
research
for
wide
range
related
applications.
Specifically,
stereolithography
apparatus
(SLA)
and
digital
light
processing
(DLP)-based
vat-polymerization
are
highly
effective
methods
bioprinting,
which
can
be
used
to
produce
high-resolution
architecturally
sophisticated
structures.
Our
review
aims
provide
an
overview
SLA-
DLP-based
3D
strategies,
starting
from
factors
that
affect
these
processes.
In
addition,
we
summarize
the
advances
bioinks
SLA
DLP,
including
naturally
derived
synthetic
bioinks.
Finally,
applications
both
discussed,
primarily
centered
on
regenerative
medicine
tissue
modeling
engineering.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(34)
Published: Jan. 22, 2024
Decellularized
extracellular
matrix
(dECM)-based
hydrogels
are
widely
applied
to
additive
biomanufacturing
strategies
for
relevant
applications.
The
components
and
growth
factors
of
dECM
play
crucial
roles
in
cell
adhesion,
growth,
differentiation.
However,
the
generally
poor
mechanical
properties
printability
have
remained
as
major
limitations
dECM-based
materials.
In
this
study,
heart-derived
(h-dECM)
meniscus-derived
(Ms-dECM)
bioinks
their
pristine,
unmodified
state
supplemented
with
photoinitiator
system
tris(2,2-bipyridyl)
dichlororuthenium(II)
hexahydrate
sodium
persulfate,
demonstrate
cytocompatibility
volumetric
bioprinting
processes.
This
recently
developed
modality
illuminates
a
dynamically
evolving
light
pattern
into
rotating
volume
bioink,
thus
decouples
requirement
strengths
bioprinted
hydrogel
constructs
printability,
allowing
fabrication
sophisticated
shapes
architectures
low-concentration
materials
that
set
within
tens
seconds.
As
exemplary
applications,
cardiac
tissues
volumetrically
using
cardiomyocyte-laden
h-dECM
bioink
showing
favorable
proliferation,
expansion,
spreading,
biomarker
expressions,
synchronized
contractions;
whereas
Ms-dECM
meniscus
structures
embedded
human
mesenchymal
stem
cells
present
appropriate
chondrogenic
differentiation
outcomes.
study
supplies
expanded
libraries
broadens
utilities
toward
tissue
engineering
regenerative
medicine.
Small,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 27, 2025
Abstract
3D
printing
has
greatly
improved
the
precision
of
cell
and
biomaterial
placement,
enabling
accurate
reproduction
tissue
models
with
sustainable
potential.
Various
techniques,
including
inkjet
printing,
extrusion‐based
vat
photopolymerization,
offer
unique
advantages
but
often
fail
to
replicate
full
complexity
native
tissues
because
material
scalability
limitations.
Hybrid
bioprinting,
combining
multiple
techniques
in
a
single
process,
shown
great
potential
creating
complex
multifunctional
capabilities,
ranging
from
patient‐specific
implant
fabrication
full‐scale
organ
development.
It
capitalizes
on
strengths
integration
sustainable,
renewable
biomaterials
at
varying
resolutions,
nano
microscale.
This
approach
addresses
both
biological
environmental
responsibility
by
minimizing
waste
enhancing
sustainability
engineering
processes.
Despite
progress,
substantial
gap
remains
between
current
technologies
bioengineering
requirements.
A
deep
understanding
hybrid
its
underlying
mechanisms
is
crucial.
Herein,
this
review
summarizes
discusses
recent
advancements
systems
for
fabricating
multiscale
hierarchical
models,
focusing
challenges
field.
aims
insights
identify
key
requirements
advancing
technology
toward
developing
functional,
biomimetic
constructs.
