Biomedical polymers: synthesis, properties, and applications

Science China Chemistry, Journal Year: 2022, Volume and Issue: 65(6), P. 1010 - 1075

Published: April 24, 2022

Language: Английский

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Versatile polyphenolic platforms in regulating cell biology

Chemical Society Reviews, Journal Year: 2022, Volume and Issue: 51(10), P. 4175 - 4198

Published: Jan. 1, 2022

Polyphenolic materials are a class of fascinating and versatile bioinspired for biointerfacial engineering. In particular, due to the presence active chemical groups, series unique physicochemical properties become accessible tunable as-prepared polyphenolic platforms, which could delicately regulate cell activities via cell-material contact-dependent interactions. More interestingly, polyphenols also affect behaviors contact-independent manner, arise their intrinsically functional characteristics (e.g., antioxidant photothermal behaviors). As such, comprehensive understanding on relationship between material desired biomedical applications, as well underlying mechanism at cellular molecular level would provide design principles accelerate lab-to-clinic translation platforms. this review, we firstly give brief overview hallmarks governed by surrounding cues, followed introduction engineering strategies. Subsequently, detailed discussion cell-polyphenols interfacial interaction was carefully provided. Lastly, applications were elaborated. We believe that review guidances rational multifunctional extend application window.

Language: Английский

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Antibacterial coatings on orthopedic implants

Materials Today Bio, Journal Year: 2023, Volume and Issue: 19, P. 100586 - 100586

Published: Feb. 15, 2023

With the aging of population and rapid improvement public health medical level in recent years, people have had an increasing demand for orthopedic implants. However, premature implant failure postoperative complications frequently occur due to implant-related infections, which not only increase social economic burden, but also greatly affect patient's quality life, finally restraining clinical use Antibacterial coatings, as effective strategy solve above problems, been extensively studied motivated development novel strategies optimize implant. In this paper, a variety antibacterial coatings recently developed implants were briefly reviewed, with focus on synergistic multi-mechanism multi-functional smart that are more potential use, thereby providing theoretical references further fabrication high-performance satisfying complex needs.

Language: Английский

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Bioinspired polydopamine hydrogels: Strategies and applications

Progress in Polymer Science, Journal Year: 2023, Volume and Issue: 146, P. 101740 - 101740

Published: Sept. 17, 2023

Language: Английский

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A robust and 3D-printed solar evaporator based on naturally occurring molecules

Science Bulletin, Journal Year: 2023, Volume and Issue: 68(2), P. 203 - 213

Published: Jan. 1, 2023

Language: Английский

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Robust and multifunctional natural polyphenolic composites for water remediation

Materials Horizons, Journal Year: 2022, Volume and Issue: 9(10), P. 2496 - 2517

Published: Jan. 1, 2022

The scarcity of clean water has become a global environmental problem which constrains the development public health, economy, and sustainability. In recent years, natural polyphenols have drawn increasing interests as promising platforms towards diverse remediation composites devices, owing to their abundant renewable resource in nature, highly active surface chemistry, multifunctionality. This review aims summarize most advances highlights polyphenol-based composite materials (e.g., nanofibers, membranes, particles, hydrogels) for remediation, by focusing on structural functional features, well diversified applications including membrane filtration, solar distillation, adsorption, advanced oxidation processes, disinfection. Finally, future challenges this field are also prospected. It is anticipated that will provide new opportunities other kinds naturally occurring molecules purification applications.

Language: Английский

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A bioinspired antibacterial and photothermal membrane for stable and durable clean water remediation

Materials Horizons, Journal Year: 2022, Volume and Issue: 10(1), P. 268 - 276

Published: Nov. 8, 2022

The tobramycin-doped polydopamine nanoparticles were developed to construct solar evaporator, which exhibited synergistic antibacterial behaviors and high water evaporation rate, thus achieving stable reuse even under microbe-rich environment.

Language: Английский

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Engineering polyphenol-based polymeric nanoparticles for drug delivery and bioimaging

Chemical Engineering Journal, Journal Year: 2022, Volume and Issue: 439, P. 135661 - 135661

Published: March 7, 2022

Language: Английский

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Applications of the ROS-Responsive Thioketal Linker for the Production of Smart Nanomedicines

Polymers, Journal Year: 2022, Volume and Issue: 14(4), P. 687 - 687

Published: Feb. 11, 2022

Reactive oxygen species (ROS)-sensitive drug delivery systems (DDS) specifically responding to altered levels of ROS in the pathological microenvironment have emerged as an effective means enhance pharmaceutical efficacy conventional nanomedicines, while simultaneously reducing side effects. In particular, use biocompatible, biodegradable, and non-toxic ROS-responsive thioketal (TK) functional group design smart DDS has grown exponentially recent years. TK-based DDS, different technological uses TK been proposed overcome major limitations counterparts including uncontrolled release off-target This review will focus on biomaterials nanomedicines by using it a linker connect surface nanoparticles, form prodrugs, core component directly control its structure, opening drug-releasing gates or change conformation nano-systems. A comprehensive view various may allow researchers exploit this reactive more consciously designing be with improved disease-targeting ability, providing novel therapeutic opportunities treatment many diseases.

Language: Английский

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pH-Responsive PVA/BC-f-GO Dressing Materials for Burn and Chronic Wound Healing with Curcumin Release Kinetics

Polymers, Journal Year: 2022, Volume and Issue: 14(10), P. 1949 - 1949

Published: May 11, 2022

Polymeric materials have been essential biomaterials to develop hydrogels as wound dressings for sustained drug delivery and chronic healing. The microenvironment healing is created by biocompatibility, bioactivity, physicochemical behavior. Moreover, a bacterial infection often causes the process. cellulose (BC) was functionalized using graphene oxide (GO) hydrothermal method cellulose-functionalized-Graphene (BC-f-GO). A simple blending used crosslink BC-f-GO with polyvinyl alcohol (PVA) tetraethyl orthosilicate (TEOS) crosslinker. structural, morphological, wetting, mechanical tests were conducted Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), water contact angle, Universal testing machine (UTM). release of Silver-sulphadiazine kinetics studied at various pH levels different mathematical models (zero-order, first-order, Higuchi, Hixson, Korsmeyer–Peppas, Baker–Lonsdale). antibacterial properties against Gram-positive Gram-negative severe infection-causing pathogens. These composite presented potential anticancer activities U87 cell line an increased GO amount. result findings show that these physical-mechanical inherent antimicrobial controlled release, making them ideal approach skin As result, discovered be biomaterial

Language: Английский

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