Metal-organic frameworks as thermocatalysts for hydrogen peroxide generation and environmental antibacterial applications DOI Creative Commons

Ajitesh Pal,

Sreerag Suresh, Arshad Khan

et al.

Science Advances, Journal Year: 2025, Volume and Issue: 11(2)

Published: Jan. 8, 2025

Reactive oxygen species (ROS) are highly reactive, making them useful for environmental and health applications. Traditionally, photocatalysts piezocatalysts have been used to generate ROS, but their utilization is limited by various physical constraints. This study introduces metal-organic frameworks (MOFs) as modern thermocatalysts efficiently producing hydrogen peroxide (H 2 O ) from small temperature differences. Temperature fluctuations, abundant in daily life, offer tremendous potential practical thermocatalytic As proof of concept, MOF materials coated onto carbon fiber fabric (MOF@CFF) created a antibacterial filter. The compared three different MOFs (CuBDC, MOF-303, ZIF-8) with bismuth telluride (Bi Te 3 ), known material. ZIF-8 demonstrated superior H generation under low-temperature differences, achieving 96% activity through variation cycles. work advances thermoelectric applications MOFs, enabling real-time purification disinfection generation. findings open interdisciplinary avenues leveraging effects catalysis technologies.

Language: Английский

Ultrasound-Augmented Multienzyme-like Nanozyme Hydrogel Spray for Promoting Diabetic Wound Healing DOI
Limin Shang, Yixin Yu, Yujie Jiang

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(16), P. 15962 - 15977

Published: Aug. 3, 2023

Treatment of diabetic foot ulcers (DFU) needs to reduce inflammation, relieve hypoxia, lower blood glucose, promote angiogenesis, and eliminate pathogenic bacteria, but the therapeutic efficacy is greatly limited by diversity synergy drug functions as well DFU microenvironment itself. Herein, an ultrasound-augmented multienzyme-like nanozyme hydrogel spray was developed using hyaluronic acid encapsulated l-arginine ultrasmall gold nanoparticles Cu1.6O coloaded phosphorus doped graphitic carbon nitride nanosheets (ACPCAH). This possesses five types enzyme-like activities, including superoxide dismutase (SOD)-, catalase (CAT)-, glucose oxidase (GOx)-, peroxidase (POD)-, nitric oxide synthase (NOS)-like activities. The kinetics reaction mechanism sonodynamic/sonothermal synergistic enhancement SOD-CAT-GOx-POD/NOS cascade ACPCAH are fully investigated. Both in vitro vivo tests demonstrate that this can be activated thus accelerating wound healing effectively. study highlights a competitive approach based on nanozymes for development all-in-one therapies.

Language: Английский

Citations

135
Recent Progress on Structure Manipulation of Poly(vinylidene fluoride)‐Based Ferroelectric Polymers for Enhanced Piezoelectricity and Applications DOI Creative Commons
Liwei Zhang,

Shuangfeng Li,

Zhiwen Zhu

et al.

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 33(38)

Published: May 28, 2023

Abstract Poly(vinylidene fluoride) (PVDF)‐based polymers demonstrate great potential for applications in flexible and wearable electronics but show low piezoelectric coefficients (e.g., − d 33 < 30 pC N −1 ). The effective improvement the piezoelectricity of PVDF is achieved by manipulating its semicrystalline structures. However, there still a debate about which component primary contributor to piezoelectricity. Therefore, current methods improve can be classified into modulations amorphous phase, crystalline region, crystalline–amorphous interface. Here, basic principles measurements soft are first discussed. Then, three different categories structural reviewed. In each category, physical understanding strategies performance particular, crucial role oriented fraction at interface determining emphasized. At last, future development high outlooked.

Language: Английский

Citations

106
Doping Engineering to Modulate Lattice and Electronic Structure for Enhanced Piezocatalytic Therapy and Ferroptosis DOI Open Access
Boshi Tian, Ruixue Tian, Shaohua Liu

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(38)

Published: July 12, 2023

Piezocatalytic therapy, which generates reactive oxygen species (ROS) under mechanical force, has garnered extensive attention for its use in cancer therapy owing to deep tissue penetration depth and less O2 -dependence. However, the piezocatalytic therapeutic efficiency is limited poor piezoresponse, low separation of electron-hole pairs, complicated tumor microenvironment (TME). Herein, a biodegradable, porous Mn-doped ZnO (Mn-ZnO) nanocluster with enhanced piezoelectric effect constructed via doping engineering. Mn-doping not only induces lattice distortion increase polarization but also creates rich vacancies (OV ) suppressing recombination leading high-efficiency generation ROS ultrasound irradiation. Moreover, shows TME-responsive multienzyme-mimicking activity glutathione (GSH) depletion ability mixed valence Mn (II/III), further aggravating oxidative stress. Density functional theory calculations show that can improve performance enzyme Mn-ZnO due presence OV . Benefiting from boosting GSH ability, significantly accelerate accumulation lipid peroxide inactivate peroxidase 4 (GPX4) induce ferroptosis. The work may provide new guidance exploring novel sonosensitizers therapy.

Language: Английский

Citations

94
Piezoelectricity, Pyroelectricity, and Ferroelectricity in Biomaterials and Biomedical Applications DOI
Yuan Xue, Jiacheng Shi, Yong Kang

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 36(3)

Published: Oct. 16, 2023

Abstract Piezoelectric, pyroelectric, and ferroelectric materials are considered unique biomedical due to their dielectric crystals asymmetric centers that allow them directly convert various primary forms of energy in the environment, such as sunlight, mechanical energy, thermal into secondary electricity chemical energy. These possess exceptional conversion ability excellent catalytic properties, which have led widespread usage within fields. Numerous applications demonstrated great potential with these materials, including disease treatment, biosensors, tissue engineering. For example, piezoelectric used stimulate cell growth bone regeneration, while pyroelectric applied skin cancer detection imaging. Ferroelectric even found use neural implants record electrical activity brain. This paper reviews relationship between ferroelectric, piezoelectric, effects fundamental principles different reactions. It also highlights preparation methods three significant progress made applications. The review concludes by presenting key challenges future prospects for efficient catalysts based on nanomaterials

Language: Английский

Citations

82
Fundamentals, advances and perspectives of piezocatalysis: A marriage of solid-state physics and catalytic chemistry DOI Creative Commons
Nan Meng, Wei Liu,

Ruyu Jiang

et al.

Progress in Materials Science, Journal Year: 2023, Volume and Issue: 138, P. 101161 - 101161

Published: July 16, 2023

Piezocatalysis, an evolving catalytic technology built on the piezoelectric properties of catalysts, breaks down barrier between mechanical energy and chemical energy. The potential difference that arises from deformation a material is commonly termed 'piezopotential'. Piezopotential has been demonstrated to facilitate manipulation band structure and/or charge carrier separation. Despite significant efforts design materials understand mechanism piezoelectrically enhanced chemistry through semiconductor physics, there remains opportunity review relationships performance piezo/ferroelectric properties. Herein, we provide comprehensive summary mechanisms correlated physical in field piezocatalysis. A fundamental understanding structural based solid-state physics can be used shed light future development In addition, types materials, strategies for catalysis efficiency enhancement, up-to-date applications environment remediation, renewable conversion, biomedicine biotechnology are discussed. Finally, perspectives designing developing highly active piezocatalysts using guidelines physicochemical proposed.

Language: Английский

Citations

79
Perspectives on recent advancements in energy harvesting, sensing and bio-medical applications of piezoelectric gels DOI Creative Commons
Thangavel Vijayakanth, Sudha Shankar, Gal Finkelstein-Zuta

et al.

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(17), P. 6191 - 6220

Published: Jan. 1, 2023

This review highlights the recent progress in piezoelectric gels (also known as PiezoGels) comprised of polymers, ceramic oxides and supramolecular materials used for energy harvesting, sensing wound dressing.

Language: Английский

Citations

70
Piezoelectric Biomaterials Inspired by Nature for Applications in Biomedicine and Nanotechnology DOI
Siying Chen, Xiaoyu Tong,

Yehong Huo

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(35)

Published: June 22, 2024

Bioelectricity provides electrostimulation to regulate cell/tissue behaviors and functions. In the human body, bioelectricity can be generated in electromechanically responsive tissues organs, as well biomolecular building blocks that exhibit piezoelectricity, with a phenomenon known piezoelectric effect. Inspired by natural bio-piezoelectric phenomenon, efforts have been devoted exploiting high-performance synthetic biomaterials, including molecular materials, polymeric ceramic composite materials. Notably, biomaterials polarize under mechanical strain generate electrical potentials, which used fabricate electronic devices. Herein, review article is proposed summarize design research progress of devices toward bionanotechnology. First, functions regulating electrophysiological activity from cellular tissue level are introduced. Next, recent advances structure-property relationship various provided detail. following part, applications engineering, drug delivery, biosensing, energy harvesting, catalysis systematically classified discussed. Finally, challenges future prospects presented. It believed this will provide inspiration for development innovative fields biomedicine nanotechnology.

Language: Английский

Citations

48
Nanocatalysts for modulating antitumor immunity: fabrication, mechanisms and applications DOI
Xianbo Wu, Yuqing Li, Mei Wen

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(5), P. 2643 - 2692

Published: Jan. 1, 2024

This review discusses the structures and engineering strategies of nanocatalysts, highlighting their underlying mechanisms applications in cancer immunotherapy.

Language: Английский

Citations

43
Piezoelectric hydrogel for treatment of periodontitis through bioenergetic activation DOI Creative Commons
Xin Liu,

Xingyi Wan,

Baiyan Sui

et al.

Bioactive Materials, Journal Year: 2024, Volume and Issue: 35, P. 346 - 361

Published: Feb. 14, 2024

The impaired differentiation ability of resident cells and disordered immune microenvironment in periodontitis pose a huge challenge for bone regeneration. Herein, we construct piezoelectric hydrogel to rescue the osteogenic capability rebuild regenerative through bioenergetic activation. Under local mechanical stress, generated piezopotential that initiates inflammatory periodontal ligament stem (PDLSCs) via modulating energy metabolism promoting adenosine triphosphate (ATP) synthesis. Moreover, it also reshapes an anti-inflammatory pro-regenerative niche switching M1 macrophages M2 phenotype. synergy tilapia gelatin stimulation enhances situ regeneration defects rats. These findings pave new pathway treating other immune-related stimulation-enabled modulation immunomodulation.

Language: Английский

Citations

39
In Situ Piezoelectric‐Catalytic Anti‐Inflammation Promotes the Rehabilitation of Acute Spinal Cord Injury in Synergy DOI

Yanling You,

Junjie Jiang, Gang Zheng

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(18)

Published: Feb. 1, 2024

Abstract Relieving inflammation via scavenging toxic reactive oxygen species (ROS) during the acute phase of spinal cord injury (SCI) proves to be an effective strategy mitigate secondary and improve recovery motor function. However, commonly used corticosteroid anti‐inflammatory drugs show adverse side effects which may induce increased risk wound infection. Fortunately, hydrogen (H 2 ), featuring selective antioxidant performance, easy penetrability, excellent biosafety, is being extensively investigated as a potential therapeutic gas for treatment SCI. In this work, by facile in situ growth approach gold nanoparticles (AuNPs) on piezoelectric BaTiO 3 , particulate nanocomposite with Schottky heterojunction (Au@BT) synthesized, can generate H continuously catalyzing + reduction through catalysis. Further, theoretical calculations are employed reveal catalytic mechanism Au@BT. Transcriptomics analysis nontargeted large‐scale metabolomic deeper neuroprotective effect therapy. The as‐prepared Au@BT nanoparticle first explored flexible generator efficient SCI This study highlights promising prospect nanocatalytic medicine disease treatments generation; thus, offering significant alternative conventional approaches against refractory injury.

Language: Английский

Citations

34