Energies,
Journal Year:
2024,
Volume and Issue:
17(13), P. 3152 - 3152
Published: June 26, 2024
Hydrogel
sweat
cooling
is
one
of
the
leading
areas
in
study
multiphase
heat
transfer.
In
this
study,
principles,
applications,
current
research
status,
and
future
trends
hydrogel
technology
are
comprehensively
reviewed.
By
combing
through
analyzing
relevant
literature,
progress
presented
from
application
perspective,
including
its
use
electronic
devices,
buildings,
clean-energy
facilities.
The
principle
each
illustrated,
status
established,
pros
cons
proposed.
To
provide
inspiration
for
research,
development
trend
set
out.
Our
literature
review
indicates
that
on
advanced
hydrogels
most
promising
direction,
studies
effect
environmental
indoor
factors
performance
numerical,
experimental,
theoretical
means.
Challenges
mainly
include
conducting
numerical
analysis
which
can
be
experimentally
verified,
developing
a
green
way,
achieving
precise
regulation
control
intelligent
methods.
Interdisciplinary
integration
might
as
well
due
to
fact
it
reveal
mechanism
different
perspective.
This
aims
promote
exploring
energy
utilization
criteria.
Materials Today Bio,
Journal Year:
2025,
Volume and Issue:
31, P. 101502 - 101502
Published: Jan. 19, 2025
DNA-based
hydrogels
stand
out
for
bone
regeneration
due
to
their
exceptional
biocompatibility
and
programmability.
These
facilitate
the
formation
of
spatial
structures
through
bulk
hydrogel
fabricating,
microsphere
formatting,
3D
printing.
Furthermore,
microenvironment
can
be
finely
tuned
by
leveraging
degradation
products,
nanostructure,
targeting,
delivery
capabilities
inherent
materials.
In
this
review,
we
underscore
advantages
hydrogels,
detailing
composition,
gelation
techniques,
structure
optimization.
We
then
delineate
three
critical
elements
in
promotion
using
hydrogels:
(i)
osteogenesis
driven
phosphate
ions,
plasmids,
oligodeoxynucleotides
(ODNs)
that
enhance
mineralization
promote
gene
protein
expression;
(ii)
vascularization
facilitated
tetrahedral
DNA
nanostructures
(TDNs)
aptamers,
which
boosts
expression
targeted
release;
(iii)
immunomodulation
achieved
loaded
factors,
TDNs,
bound
ions
stimulate
macrophage
polarization
exhibit
antibacterial
properties.
With
these
properties,
used
construct
organoids,
providing
an
innovative
tool
disease
modeling
therapeutic
applications
tissue
engineering.
Finally,
discuss
current
challenges
future
prospects,
emphasizing
potential
impacts
regenerative
medicine.
Materials Today Bio,
Journal Year:
2025,
Volume and Issue:
31, P. 101509 - 101509
Published: Jan. 22, 2025
Articular
cartilage,
composed
of
chondrocytes
within
a
dynamic
viscoelastic
matrix,
has
limited
self-repair
capacity,
posing
significant
challenge
for
regeneration.
Constructing
high-fidelity
cartilage
organoids
through
three-dimensional
(3D)
bioprinting
to
replicate
the
structure
and
physiological
functions
is
crucial
regenerative
medicine,
drug
screening,
disease
modeling.
However,
commonly
used
matrix
bioinks
lack
reversible
cross-linking
precise
controllability,
hindering
cellular
regulation.
Thus,
encoding
adaptive
cultivating
an
attractive
idea.
DNA,
with
its
ability
be
intricately
encoded
reversibly
cross-linked
into
hydrogels,
offers
manipulation
at
both
molecular
spatial
structural
levels.
This
endows
hydrogels
viscoelasticity,
printability,
cell
recognition,
stimuli
responsiveness.
paper
elaborates
on
strategies
encode
bioink
via
emphasizing
regulation
predictable
properties
resulting
interactions
behavior.
The
significance
these
construction
highlighted.
Finally,
we
discuss
challenges
future
prospects
using
DNA-encoded
3D
bioprinted
organoids,
underscoring
their
potential
impact
advancing
biomedical
applications.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(33)
Published: June 6, 2024
The
growing
aging
population,
with
its
associated
chronic
diseases,
underscores
the
urgency
for
effective
tissue
regeneration
strategies.
Biomaterials
play
a
pivotal
role
in
realm
of
reconstruction
and
regeneration,
distinct
shift
toward
minimally
invasive
(MI)
treatments.
This
transition,
fueled
by
engineered
biomaterials,
steers
away
from
surgical
procedures
to
embrace
approaches
offering
reduced
trauma,
accelerated
recovery,
cost-effectiveness.
In
MI
repair
cargo
delivery,
various
techniques
are
explored.
While
situ
polymerization
is
prominent,
it
not
without
challenges.
narrative
review
explores
diverse
fabrication
methods,
biofunctionalization
injectable
pre-formed
scaffolds,
focusing
on
their
unique
advantages.
exhibiting
compressibility,
controlled
injection,
maintained
mechanical
integrity,
emerge
as
promising
alternative
solutions
conclusion
this
emphasizes
importance
interdisciplinary
design
facilitated
synergizing
fields
materials
science,
advanced
3D
biomanufacturing,
mechanobiological
studies,
innovative
regeneration.
Medical Review,
Journal Year:
2024,
Volume and Issue:
4(3), P. 207 - 224
Published: March 26, 2024
Abstract
RNA-based
therapeutics
have
emerged
as
a
promising
approach
for
the
treatment
of
various
diseases,
including
cancer,
genetic
disorders,
and
infectious
diseases.
However,
delivery
RNA
molecules
into
target
cells
has
been
major
challenge
due
to
their
susceptibility
degradation
inefficient
cellular
uptake.
To
overcome
these
hurdles,
DNA-based
nano
technology
offers
an
unprecedented
opportunity
potential
platform
therapeutics.
Due
its
excellent
characteristics
such
programmability
biocompatibility,
nanostructures,
composed
DNA
assembled
precise
programmable
structures,
garnered
significant
attention
ideal
building
materials
protecting
delivering
payloads
desired
destinations.
In
this
review,
we
highlight
current
progress
in
design
application
three
nanostructures:
origami,
lipid-nanoparticle
(LNP)
related
frame
guided
assembly
(FGA),
hydrogel
molecules.
Their
biomedical
applications
are
briefly
discussed
challenges
future
perspectives
field
also
highlighted.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(24)
Published: April 5, 2024
Abstract
The
finite
periodic
arrangement
of
functional
nanomaterials
on
the
two‐dimensional
scale
enables
integration
and
enhancement
individual
properties,
making
them
an
important
research
topic
in
field
tuneable
nanodevices.
Although
layer‐controllable
lattices
such
as
graphene
have
been
successfully
synthesized,
achieving
similar
control
over
colloidal
nanoparticles
remains
a
challenge.
DNA
origami
technology
has
achieved
remarkable
breakthroughs
programmed
nanoparticle
assembly.
Based
this
technology,
we
proposed
hierarchical
assembly
strategy
to
construct
universal
platform
with
customized
layer
which
called
2.5‐dimensional
(2.5D)
crystals.
Methodologically,
divides
procedure
into
two
steps:
1)
array
synthesis,
2)
lattice
means
that
including
number,
interlayer
distance,
surface
morphology,
can
be
flexibly
based
independent
designs
each
step.
In
practice,
these
synthesized
2.5D
crystals
not
only
pioneer
expansion
crystal
library
wider
range
dimensions,
but
also
highlight
technological
potential
for
templating
nanomaterial
lattices.
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 2, 2025
High
transductive
loss
at
tissue
injury
sites
impedes
repair.
The
high
dissipation
characteristics
in
the
electromechanical
conversion
of
piezoelectric
biomaterials
pose
a
challenge.
Therefore,
supramolecular
engineering
and
microfluidic
technology
is
utilized
to
introduce
slide-ring
polyrotaxane
conductive
polypyrrole
construct
stress-electric
coupling
hydrogel
microspheres.
molecular
slippage
mechanism
structure
stores
releases
mechanical
energy,
reducing
loss,
barium
titanate
enables
stress-electricity
conversion,
conjugated
π-electron
movement
network
improves
internal
electron
transfer
efficiency
microspheres,
thereby
for
first
time.
Compared
traditional
low-dissipation
microspheres
increased
by
2.3
times,
energy
decreased
43%.
At
cellular
level,
electrical
signals
generated
triggered
Ca
Advanced Healthcare Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 10, 2025
Abstract
DNA
hydrogels
have
emerged
as
promising
materials
in
tissue
engineering
due
to
their
biocompatibility,
programmability,
and
responsiveness
stimuli.
Synthesized
through
physical
chemical
crosslinking,
these
can
be
categorized
into
functionalized
types,
such
those
based
on
aptamers,
stimuli‐responsive
types
that
react
pH,
temperature,
light.
This
review
highlights
applications
engineering,
including
drug
delivery,
cell
culture,
biosensing,
gene
editing.
encapsulate
therapeutic
agents,
support
growth,
respond
dynamically
environmental
changes,
making
them
ideal
for
engineering.
A
comprehensive
bibliometric
analysis
is
included,
identifying
key
research
trends
emerging
areas
of
interest
hydrogel
design,
synthesis,
biomedical
applications.
The
provides
a
deeper
understanding
the
field's
development
future
directions.
Challenges
mechanical
strength,
stability,
biosafety
persist,
but
integration
AI
design
shows
promise
advancing
functionality
clinical
Polymers,
Journal Year:
2025,
Volume and Issue:
17(8), P. 1108 - 1108
Published: April 19, 2025
The
modeling
and
simulation
of
polymer
systems
present
unique
challenges
due
to
their
intrinsic
complexity
multi-scale
behavior.
Traditional
computational
methods,
while
effective,
often
struggle
balance
accuracy
with
efficiency,
especially
when
bridging
the
atomistic
macroscopic
scales.
Recently,
physics-informed
neural
networks
(PINNs)
have
emerged
as
a
promising
tool
that
integrates
data-driven
learning
governing
physical
laws
system.
This
review
discusses
development
application
PINNs
in
context
science.
It
summarizes
recent
advances,
outlines
key
methodologies,
analyzes
benefits
limitations
using
for
property
prediction,
structural
design,
process
optimization.
Finally,
it
identifies
current
future
research
directions
further
leverage
advanced
modeling.
