Journal of Polymer Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 10, 2025
ABSTRACT
Skin
defects
caused
by
injuries
such
as
burns
that
exceed
a
certain
diameter
no
longer
heal
spontaneously
and
require
more
complex
interventions.
Hydrogels
have
received
special
attention
due
to
their
unique
ability
block
the
penetration
of
bacteria
into
wounds
they
can
absorb
contaminated
exudates
exhibit
high
degree
flexibility.
This
study
is
focused
on
preparation
characterization
novel
antibacterial
biocomposite
hydrogels
based
two
carbohydrates,
alginate
hyaluronic
acid
(HA),
with
immobilized
ZnO
NPs
curcumin‐loaded
electrospun
nanofibers
improve
efficacy
wound
healing
process.
The
hydrogel
matrix
was
obtained
after
crosslinking
HA
in
presence
DMT‐MM
activator.
were
physicochemically
characterized
FT‐IR,
scanning
electron
microscopy
(SEM),
UV–Vis
spectroscopy,
swelling
also
investigated.
It
appeared
behavior
influenced
amount
nanofibers.
Biodegradability,
hemolysis,
cell
viability,
antimicrobial,
vitro
irritability
tests
carried
out
assess
biological
properties.
results
highlighted
these
are
biodegradable,
hemocompatible,
non‐cytotoxic,
non‐irritating
good
antimicrobial
activity.
Based
results,
materials
might
be
interesting
candidates
for
treatment.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(7), P. 1914 - 1914
Published: July 9, 2023
Wound
healing
is
a
complex
process
that
involves
restoring
the
structure
of
damaged
tissues
through
four
phases:
hemostasis,
inflammation,
proliferation,
and
remodeling.
dressings
are
most
common
treatment
used
to
cover
wounds,
reduce
infection
risk
loss
physiological
fluids,
enhance
wound
healing.
Despite
there
being
several
types
based
on
different
materials
fabricated
various
techniques,
polymeric
films
have
been
widely
employed
due
their
biocompatibility
low
immunogenicity.
Furthermore,
they
non-invasive,
easy
apply,
allow
gas
exchange,
can
be
transparent.
Among
methods
for
designing
films,
solvent
casting
represents
reliable,
preferable,
highly
technique
its
easygoing
relatively
low-cost
procedure
compared
sophisticated
such
as
spin
coating,
microfluidic
spinning,
or
3D
printing.
Therefore,
this
review
focuses
obtained
using
technique,
emphasizing
critical
manufacturing
factors
related
pharmaceuticals,
specifically
discussing
formulation
variables
necessary
create
demonstrate
effective
performance.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(13), P. 10738 - 10738
Published: June 27, 2023
Antibacterial
chitosan
films,
versatile
and
eco-friendly
materials,
have
garnered
significant
attention
in
both
the
food
industry
medicine
due
to
their
unique
properties,
including
biodegradability,
biocompatibility,
antimicrobial
activity.
This
review
delves
into
various
types
of
films
distinct
applications.
The
categories
discussed
span
from
pure
those
enhanced
with
additives
such
as
metal
nanoparticles,
oxide
graphene,
fullerene
its
derivatives,
plant
extracts.
Each
type
film
is
examined
terms
synthesis
methods
establishing
a
clear
understanding
potential
utility.
In
industry,
these
shown
promise
extending
shelf
life
maintaining
quality.
medical
field,
they
been
utilized
for
wound
dressings,
drug
delivery
systems,
antibacterial
coatings
devices.
further
suggests
that
incorporation
different
can
significantly
enhance
properties
films.
While
vast,
underscores
need
future
research
focused
on
optimizing
methods,
structure-property
relationships,
rigorous
evaluation
safety,
long-term
stability
real-world
Fibers,
Journal Year:
2024,
Volume and Issue:
12(3), P. 26 - 26
Published: March 12, 2024
This
review
is
focused
on
the
recent
development
of
various
chitosan-based
nanofibers
(membranes,
patches,
mats,
and
scaffolds)
that
have
been
designed
into
core
shell
structures
using
emulsion
coaxial
electrospinning
techniques.
Chitosan,
a
promising
polysaccharide
derived
from
natural
sources,
holds
potential
for
diverse
applications,
including
nanofiber
production,
aimed
at
fostering
sustainability.
Core/shell
offer
appealing
features,
drug
encapsulation
sustained
release
capabilities,
with
higher
efficiency
than
uniaxial
fibers.
The
fabrication
core/shell
nanofibers,
co-spinning
agents
spinning
parameters,
such
as
voltage,
needle
size,
flow
rate,
distance
tip
to
collector,
temperature,
humidity,
summarized
in
this
work.
also
explores
updated
applications
fields,
textiles,
medical
dressings,
systems,
filtration
membranes,
food
packaging.
It
highlights
current
advancements
produced
via
innovative
insights
presented
literature
challenges
associated
these
sustainable
materials
are
thoroughly
examined,
offering
valuable
contributions
field.
ACS Applied Materials & Interfaces,
Journal Year:
2023,
Volume and Issue:
15(48), P. 55276 - 55286
Published: Nov. 22, 2023
To
overcome
the
drawbacks
of
single-layered
wound
dressings,
bilayer
dressings
are
now
introduced
as
an
alternative
to
achieve
effective
and
long-term
treatment.
Here,
a
dressing
composed
electrospun
nanofibers
in
bottom
layer
(BL)
sponge
structure
top
(TL)
is
presented.
Hydrophilic
poly(acrylic
acid)
(PAAc)-honey
(Hny)
with
interconnected
pores
76.04
μm
was
prepared
TL
keratin
(Kr),
Hny,
vascular
endothelial
growth
factor
(VEGF)
were
BL.
VEGF
indicates
gradual
release
over
7
days,
promoting
angiogenesis,
proven
by
chick
chorioallantoic
membrane
assay
vivo
tissue
histomorphology
observation.
Additionally,
fabricated
material
indicated
satisfactory
tensile
profile,
cytocompatibility
for
human
keratinocyte
cells,
ability
promote
cell
attachment
migration.
The
animal
model
demonstrated
that
full-thickness
healed
faster
when
it
covered
PAAc-Hny/Hny-Kr-VEGF
than
other
groups.
blood
vessel
formation,
collagen
synthetization,
epidermal
generation
also
confirmed,
which
have
efficient
healing
acceleration
wounds
treated
synthesized
dressings.
Our
findings
can
be
promising
functional
dressing.
