Advances in Colloid and Interface Science,
Journal Year:
2024,
Volume and Issue:
331, P. 103248 - 103248
Published: July 15, 2024
Polypeptides
have
shown
an
excellent
potential
in
nanomedicine
thanks
to
their
biocompatibility,
biodegradability,
high
functionality,
and
responsiveness
several
stimuli.
exhibit
propensity
organize
at
the
supramolecular
level;
hence,
they
been
extensively
considered
as
building
blocks
layer-by-layer
(LbL)
assembly.
The
LbL
technique
is
a
highly
versatile
methodology,
which
involves
sequential
assembly
of
blocks,
mainly
driven
by
electrostatic
interactions,
onto
planar
or
colloidal
templates
fabricate
sophisticated
multilayer
nanoarchitectures.
simplicity
mild
conditions
required
approach
led
inclusion
biopolymers
bioactive
molecules
for
fabrication
wide
spectrum
biodegradable,
biocompatible,
precisely
engineered
films
biomedical
applications.
This
review
focuses
on
those
examples
polypeptides
used
nanoarchitectures
tissue
engineering
drug
delivery
applications,
highlighting
characteristics
strategies
adopted
increase
stability
film.
Cross-linking
presented
powerful
strategy
enhance
stiffness
network,
fundamental
requirement
For
example,
engineering,
stiff
coating,
presence
adhesion
promoters,
and/or
boost
adhesion,
growth,
differentiation
cells.
On
contrary,
antimicrobial
coatings
should
repel
inhibit
growth
bacteria.
In
focused
particles
capsules
micro-
nano-meter
scale,
film
crucial
terms
retention
controlled
release
payload.
Recent
advances
key
role
adsorption
genetic
material
with
loading
efficiency,
addressing
different
pathways
particles/capsules
during
intracellular
uptake,
paving
way
applications
personalized
medicine.
Although
there
are
few
studies,
pH
changes,
together
stimuli-responsive
entities
into
represents
further
factor
development
smart
systems
promote
sustained
therapeutics.
degradability
may
be
obstacle
certain
scenarios
once
external
stimulus
applied.
Nowadays,
design
biodegradable
oriented
theranostics
that,
limited
use
polypeptides,
still
infancy.
Chemical Society Reviews,
Journal Year:
2023,
Volume and Issue:
52(17), P. 6191 - 6220
Published: Jan. 1, 2023
This
review
highlights
the
recent
progress
in
piezoelectric
gels
(also
known
as
PiezoGels)
comprised
of
polymers,
ceramic
oxides
and
supramolecular
materials
used
for
energy
harvesting,
sensing
wound
dressing.
The Journal of Physical Chemistry B,
Journal Year:
2023,
Volume and Issue:
127(9), P. 1857 - 1871
Published: Feb. 22, 2023
The
design
of
novel
cancer
drug
nanocarriers
is
critical
in
the
framework
therapeutics.
Nanomaterials
are
gaining
increased
interest
as
delivery
systems.
Self-assembling
peptides
constitute
an
emerging
class
highly
attractive
nanomaterials
with
promising
applications
delivery,
they
can
be
used
to
facilitate
release
and/or
stability
while
reducing
side
effects.
Here,
we
provide
a
perspective
on
peptide
self-assembled
for
and
highlight
aspects
metal
coordination,
structure
stabilization,
cyclization,
well
minimalism.
We
review
particular
challenges
nanomedicine
criteria
and,
finally,
future
perspectives
addressing
portion
via
self-assembling
consider
that
intrinsic
advantages
such
systems,
along
increasing
progress
computational
experimental
approaches
their
study
design,
could
possibly
lead
classes
single
or
multicomponent
systems
incorporating
materials
delivery.
ACS Nano,
Journal Year:
2023,
Volume and Issue:
18(2), P. 1257 - 1288
Published: Dec. 29, 2023
Inspired
by
natural
hierarchical
self-assembly
of
proteins
and
peptides,
amino
acids,
as
the
basic
building
units,
have
been
shown
to
self-assemble
form
highly
ordered
structures
through
supramolecular
interactions.
The
fabrication
functional
biomaterials
comprised
extremely
simple
biomolecules
has
gained
increasing
interest
due
advantages
biocompatibility,
easy
functionalization,
structural
modularity.
In
particular,
acid
based
assemblies
attractive
physical
characteristics
for
various
bionanotechnology
applications.
Herein,
we
propose
a
review
paper
summarize
design
strategies
well
research
advances
smart
materials.
We
first
briefly
introduce
bioinspired
reductionist
assembly
mechanism
molecular
materials
noncovalent
interactions
in
condensed
states,
including
self-assembly,
metal
ion
mediated
coordination
assembly,
coassembly.
following
part,
provide
an
overview
properties
functions
toward
applications
nanotechnology
biomedicine.
Finally,
give
remaining
challenges
future
perspectives
on
with
desired
properties.
believe
that
this
will
promote
prosperous
development
innovative
formed
minimalistic
blocks.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(14)
Published: Jan. 11, 2024
Protein
self-assembly
is
a
fundamental
biological
process
where
proteins
spontaneously
organize
into
complex
and
functional
structures
without
external
direction.
This
crucial
for
the
formation
of
various
functionalities.
However,
when
protein
fails,
it
can
trigger
development
multiple
disorders,
thus
making
understanding
this
phenomenon
extremely
important.
Up
until
recently,
has
been
solely
linked
either
to
function
or
malfunction;
however,
in
past
decade
two
also
found
hold
promising
potential
as
an
alternative
route
fabricating
materials
biomedical
applications.
It
therefore
necessary
timely
summarize
key
aspects
self-assembly:
how
structure
conditions
(chemical
environments,
kinetics,
physicochemical
characteristics
complexes)
be
utilized
design
biomaterials.
minireview
focuses
on
basic
concepts
forming
supramolecular
structures,
existing
routes
modifications.
We
then
compare
applicability
different
approaches,
including
compartmentalization
monitoring.
Finally,
based
cutting-edge
progress
made
during
last
years,
we
current
knowledge
about
tailoring
final
by
introducing
changes
link
biomaterials'
performance.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(29)
Published: March 18, 2024
Abstract
Biologically
inspired
peptide‐based
materials,
as
novel
charge
transport
have
gained
increasing
interest
in
bioelectronics
due
to
their
remarkable
electrical
properties
and
inherent
biocompatibility.
Extensive
studies
shown
that
peptides
can
self‐assemble
into
a
variety
of
hierarchical
nanostructures
with
unique
physical
through
supramolecular
interactions.
Therefore,
materials
hold
great
promise
for
applications
emerging
electronic
fields
such
sensing,
energy
harvesting,
storage,
transmission.
Herein,
this
work
proposes
review
article
summarize
the
rational
design
research
progress
devices
bioelectronics.
This
first
introduces
strategies
assembly
mechanism
constructing
high‐performance
devices.
In
following
part,
are
systematically
classified
discussed,
including
sensors,
piezoelectric
nanogenerators,
electrodes,
semiconductors.
Finally,
remaining
challenges
future
perspectives
bioelectronic
presented.
believes
will
provide
inspiration
guidance
development
innovative
smart
field
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(8), P. 3714 - 3773
Published: Jan. 1, 2024
Self-assembled
monolayers
(SAMs)
based
on
peptides
represent
a
reproducible
platform
for
screening
and
studying
peptide
functions
facilitating
their
translation
into
multidisciplinary
applications.
