Russian Journal of Infection and Immunity,
Journal Year:
2023,
Volume and Issue:
13(5), P. 885 - 898
Published: Oct. 20, 2023
Introduction.
As
the
COVID-19
pandemic
continues
to
pose
a
significant
challenge
global
health,
effective
therapeutic
options
for
preventing
and
treating
disease
have
become
increasingly
important.
We
aimed
provide
an
update
on
current
treatments
patients.Materials
methods.
The
purpose
of
this
umbrella
review
is
explore
patients.
Keywords
their
combinations
were
searched
across
online
databases
in
Embase,
PubMed/MEDLINE,
Web
Science,
Scopus
spanning
from
July
1,
2020,
through
March
3,
2023.
Publications
selected
data
extraction
two
steps
based
study
inclusion/exclusion
criteria.
adheres
PRISMA
checklist
as
well
NIH
bias
risk
quality
assessment
tool.Results.
In
review,
28
relevant
articles
final
qualitative
synthesis.
majority
included
studies
had
reported
efficacy
Lopinavir/Ritonavir
(n
=
4),
Ivermectin
3),
Baricitinib
2),
Tocilizumab
Remdesivir
ACEI/ARB
Vitamin
D
Molnupiravir
Traditional
Chinese
medicine
(TCM)
Convalescent
plasma
transfusion
(CPT)
2)
hydroxychloroquine
COVID-19.
It
appeared
that
Baricitinib,
Remdesivir,
ACEI/ARB,
TCM,
CPT
may
beneficial
effects
reducing
mortality,
hospitalization
duration,
severity
Other
interventions,
such
Lopinavir/Ritonavir,
Ivermectin,
D,
Hydroxychloroquine
did
not
show
clear
benefits
or
inconclusive
results.Conclusion.
This
provides
comprehensive
overview
evidence
effectiveness
safety
various
pharmacological
non-pharmacological
interventions
These
results
updated
landscape
treatments,
highlighting
potential
avenues
further
research
clinical
practice.
crucial
continue
monitoring
emerging
conducting
rigorous
guide
development
optimization
strategies
against
Health Science Reports,
Journal Year:
2022,
Volume and Issue:
5(2)
Published: Feb. 15, 2022
Abstract
Background
and
Aims
The
outbreak
of
coronavirus
disease
2019
(COVID‐19)
over
the
past
year
has
affected
public
health
worldwide.
During
pregnancy,
maternal
immune
system
inflammatory
responses
are
widely
suppressed.
Pregnancy‐related
suppression
could
make
mother
vulnerable
to
infectious
diseases
like
SARS‐COV‐2.
However,
current
data
suggest
little
no
possibility
COVID‐19
transmission
in
pregnant
women
fetus
during
pregnancy
or
childbirth.
This
systematic
review
focused
on
possible
complications
infection
newborn
babies
including
evidence
vertical
by
reviewing
articles
published
first
pandemic.
Methods
We
conducted
a
search
using
keywords
PubMed,
Embase,
Scopus
databases.
studies
followed
title/abstract
full‐text
screening
process,
eligible
were
included
study.
Results
In
total,
238
papers
identified
strategy
(44
met
inclusion
criteria
final
review).
all
studies,
total
2375
with
signs
symptoms
COVID‐19,
who
second
third
trimester
assessed
mild
moderate
pneumonia
was
one
most
common
symptoms.
Seventy‐three
percent
did
not
present
any
comorbidity,
19%
had
fever,
17%
cough
as
frequent
clinical
symptoms,
7.5%
pulmonary
changes
chest
scans,
8%
increased
C
reactive
protein,
9.4%
decreased
lymphocytes
(lymphocytopenia).
A
2716
newborns
fetal
assessed;
delivery
method
1725
them
reported,
913
(53%)
through
C‐section
delivery,
812
normal
vaginal
(47%).
Of
newborns,
13
died
(five
along
mother),
1965
tested
for
SARS‐CoV‐2:118
positive.
study,
seven
cases
reported
145
assessed.
Conclusion
It
appeared
that
COVID
patients
mildly
ill,
there
is
currently
convincing
support
disease.
Therefore,
neonates
do
represent
additional
risk
adverse
outcomes
neither
prenatal
period
nor
after
birth.
Journal of Neonatal-Perinatal Medicine,
Journal Year:
2023,
Volume and Issue:
16(2), P. 227 - 234
Published: April 21, 2023
Infection
with
COVID-19
during
pregnancy
has
been
associated
a
hypercoagulable
state.
It
is
unknown
if
maternal
infection
results
in
congenital
anomalies
secondary
to
intrauterine
vascular
accidents.
This
study
sought
determine
the
rate
of
in-utero
complications
(intestinal
atresia
and
limb
abnormalities)
that
may
be
attributable
states
increased
after
onset
pandemic.Pregnancy,
neonatal,
defect
data
from
single
academic
medical
center
partner's
children's
hospital
were
collected
compared
period
prior
pandemic.
A
subanalysis
including
pregnant
woman
18
years
or
greater
documented
gestation
between
March
2020-2021
was
performed.Rates
intestinal
did
not
differ
pandemic
(3.78%
vs
7.23%,
p
=
0.21)
nor
rates
deficiency
disorders
(4.41%
9.65%,
0.09).
On
subanalysis,
there
194
women
included
analysis:
135
(69.6%)
positive
delivery
admission
59
(30.4%)
earlier
their
pregnancy.
There
one
infant
born
atresia.We
report
low
incidence
infants
mothers
infection.
remains
unclear
impact
on
coagulative
state
augments
normal
pro-thrombotic
pregnancy;
ongoing
surveillance
warranted.
Journal of Pregnancy,
Journal Year:
2023,
Volume and Issue:
2023, P. 1 - 21
Published: May 13, 2023
Background.
COVID-19
is
a
new
pandemic,
which
was
declared
by
the
World
Health
Organization
in
2019
as
threat
to
public
health.
According
numerous
reports,
it
can
have
negative
consequences
for
pregnant
women,
labour,
and
neonates
born
infected
mothers.
The
aim
of
this
paper
gather
evidence
present
summary
results
studies
concerning
women
their
neonates.
Methods.
Articles
from
prestigious
journals
covering
period
2020
February
2023,
relevant
review
papers,
original
research
articles
PubMed
were
analysed.
In
order
analyse
available
literature,
Web
Science,
Scopus,
databases
used,
search
conducted
using
terms
(“pregnancy,”
“coronavirus,”
“SARS-CoV-2,”
“newborn”)
PRISMA
(Preferred
Reporting
Items
Systemic
Reviews
Meta-Analysis)
guidelines
clinical
trials.
Meta-analyses
systematic
reviews
(2022–2023)
on
symptoms,
neonatal
course,
risk
infection
been
summarized.
Summary
meta-analyses
effect
adverse
reaction
vaccination
presented.
Results.
As
result
conducted,
confirmed
that
most
no
serious
signs
observed,
although
isolated
cases
death
related
reported.
Several
authors
called
attention
more
severe
course
with
obesity.
It
seemed
vertical
transmission
mother
child
occurring.
Nevertheless,
information
not
clinching.
condition
mothers
described
normal;
however,
some
papers
reported
deaths
Conclusions.
Due
insufficient
data,
further
necessary.
Further
follow-up
are
recommended,
would
make
possible
an
assessment
remote
effects
pregnancy
vital
parameters
newborn.
BMC Pediatrics,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: July 16, 2024
The
impact
of
the
Coronavirus
Disease
2019
(COVID-19)
on
society
is
continuous,
resulting
in
negative
psychological
consequences.
Given
vulnerability
and
sensitivity
to
environment
among
preschool
children,
their
emotional
behavioral
problems
deserve
more
attention.
current
study
aimed
explore
epidemic
children's
mental
health
by
determining
pooled
prevalence
amidst
pandemic
reveal
potential
reasons
for
variations
between
studies.
Published
studies
were
searched
Embase,
PubMed,
ProQuest,
PsycINFO,
Web
Science,
CNKI,
Wanfang.
Based
inclusion
criteria
outlined
this
study,
a
total
10
encompassing
38,059
participants
incorporated.
Employing
random-effect
model
estimating
problems,
results
revealed
rate
24.3%
(95%
CI,
0.15-0.38;
I²=99.9%)
children.
This
surpasses
pre-outbreak
observed
different
countries,
signifying
detrimental
influence
well-being
preschoolers.
Therefore,
care
recovery
are
essential
vulnerable
group
during
after
public
crisis.
Specific
children
expected
be
researched
future
provide
targeted
guidance
intervention.
Annals of Medicine and Surgery,
Journal Year:
2022,
Volume and Issue:
80
Published: Aug. 1, 2022
Due
to
the
COVID-19
pandemic,
hospitals
have
become
unsafe
for
patients
as
potential
sources
of
virus
transmission.
This
study
aims
determine
infection
rate
after
primary
total
hip
arthroplasty
(THA)
among
unvaccinated
patients.
THA
undergoing
elective
or
traumatic
(urgent)
were
compared
regarding
contraction.Primary
prospectively
followed
from
three
in
*two
great
cities*
country
between
April
2020
August
2021.
If
patient
had
suspected
symptoms,
a
SARS-CoV-2
PCR
test
nasopharyngeal
and
oropharyngeal
swabs
and/or
chest
CT
scan.Finally,
information
was
received
436
patients,
including
345
(79.1%)
91
(20.9%)
THAs.
Eight
(1.8%)
contracted
within
month
discharge,
two
died
due
COVID-19.
There
no
statistical
difference
disease
type
surgery
(elective
1.4%
versus
3.3%,
P
=
0.24).
Women
(Odds
ratio
(95%
CI)
8.5
(2.1-35.2),
0.01)
those
who
heart
with
Haldane-Anscombe
correction
≈
14.0,
more
likely
contract
postoperatively.In
both
urgent
cases
THA,
researchers
found
that
there
is
not
high
risk
contracting
during
peri-surgery
period.
Urgent
surgeries
are
comparable
THA-with
strict
pre-elective
protocols-in
terms
hospital
stay
if
appropriate
health
protocols
followed.
Frontiers in Pediatrics,
Journal Year:
2023,
Volume and Issue:
11
Published: Jan. 25, 2023
Background
The
kangaroo-mother
care
method
(KMC)
is
a
skin-to-skin
contact-centered
approach
with
numerous
benefits
for
neonates,
but
its
impact
on
the
treatment
of
jaundiced
neonates
unknown.
This
study
aimed
to
investigate
efficacy
KMC
combined
neonatal
phototherapy
(NNPT)
in
treating
non-pathological
jaundice.
Methods
Relevant
articles
were
searched
PubMed,
Embase,
Web
Science,
and
Cochrane
Library
databases
from
database
establishment
April
2022.
outcomes
included,
without
limitation,
serum
bilirubin
levels,
duration
phototherapy.
Results
meta-analysis
included
five
studies
(4
randomized
controlled
trials
1
observational
study)
involving
four
hundred
eighty-two
results
showed
that
group
receiving
NNPT
had
lower
at
72
h
after
intervention
[weighted
mean
difference
(WMD)
=
−1.51,
p
0.03],
shorter
[standard
(SMD)
−1.45,
<
0.001]
hospitalization
(SMD
−1.32,
0.002)
compared
group.
There
was
no
peak
both
groups
(WMD
−0.12,
0.62).
Conclusions
helped
treat
jaundice
newborns
alone.
Viruses,
Journal Year:
2023,
Volume and Issue:
15(7), P. 1615 - 1615
Published: July 24, 2023
Objectives:
To
determine
risk
factors
for
primary
and
secondary
adverse
neonatal
outcomes
in
newborns
with
congenital
SARS-CoV-2
infection.
Data
sources:
PubMed/MEDLINE
Google
Scholar
from
January
2020
to
2022.
Study
eligibility
criteria:
delivered
after
24
weeks
of
gestation
confirmed/possible
infection,
according
standard
classification
criteria.
Methods:
Execution
the
IPD
analyses
followed
PRISMA-IPD
statement.
Univariate
non-parametric
tests
compared
numerical
data
distributions.
Fisher’s
exact
or
Chi-square
test
determined
categorical
variables’
statistical
significance.
Multivariate
logistic
regression
revealed
outcome.
Results:
Maternal
fever
was
associated
symptomatic
infection
(OR:
4.55,
95%
CI:
1.33–15.57).
Two-thirds
women
that
reported
decreased
fetal
movements
were
diagnosed
IUFD
(p-value
=
0.001).
Reduced
movement
increased
intrauterine
death
by
7.84
times
0.016,
2.23–27.5).
The
stillbirth
gestational
age
at
time
maternal
<
0.05,
OR:
0.87,
0.79–0.97).
Conclusions:
perception
reduced
may
be
predictive
pregnancy
outcome
cases
Journal of Infection and Public Health,
Journal Year:
2022,
Volume and Issue:
15(12), P. 1503 - 1507
Published: Nov. 11, 2022
Understanding
the
impact
of
SARS-CoV-2
infection
on
pregnancy
outcomes
and
COVID-19
is
critical
for
ensuring
proper
prenatal
antenatal
care.
No
similar
studies
have
been
published
in
Saudi
Arabia.
We
performed
a
prospective
cohort
study
pregnant
women
with
confirmed
who
presented
at
King
Faisal
Specialist
Hospital
Research
Center
(KFSHRC)
Riyadh,
Kingdom
staging
was
performed,
pregnancy-related
complications
were
assessed,
neonatal
evaluated.
enrolled
81
patients
(mean
age
31.75
years,
SD
5.25)
which
there
17
cases
first
trimester,
20
second
34
third
trimester.
The
distribution
severity
40
Stage
A,
36
B,
4
C,
1
D.
Complications
loss
2
(one
each
trimester)
fetal
death
after
weeks
pregnancy,
7
growth
restriction,
8
pre-term
delivery.
did
not
observe
an
unusual
frequency
due
to
this
high-risk
obstetric
population
no
evidence
vertical
transmission
newborns
from
delivered
while
positive
virus.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 26, 2024
Background:
Preterm
premature
rupture
of
membranes
(PPROM)
is
the
fetal
before
38
weeks
gestation.
The
etiology
multifactorial.
Maternal
anemia
one
factors
leading
to
PPROM.
This
study
aims
determine
frequency
maternal
in
patients
presenting
with
Materials
and
Methods:
cross-sectional
was
carried
out
at
Department
Obstetrics
Gynecology,
Lady
Reading
Hospital,
Peshawar.
conducted
from
July
1
December
31,
2021.
One
hundred
twenty
two
PPROM
Gynecology
were
included.
diagnosis
made
based
on
history
PV
leak,
followed
by
confirmation
nitrazine
litmus
test,
microscopic
fern
ultrasonographic
amniotic
fluid
index
measurement.
Anemia
determined
examination
hemoglobin
levels
blood
samples.
Hb
<11gm/dl
labeled
as
anemia.
IBM
Corp.
Released
2011.
SPSS
Statistics
for
Windows,
Version
20.0.
Armonk,
NY:
used
statistical
analysis.
Results:
age
ranged
20
40
years.
mean
29.14
±
6.194
63
(51.6%)
multiparous
(parity
2
4).
observed
39
(32.0%).
A
significant
association
(p
=
0.005)
between
grand
multiparity
Conclusion:
significantly
contributes
PPROM,
especially
multiple
pregnancies.
Meticulous
family
planning
consistent
obstetrical
monitoring
throughout
pregnancy
are
key
addressing
this,
potentially
reducing
both
risk
complications.