Biogerontology, Journal Year: 2024, Volume and Issue: 25(4), P. 583 - 613
Published: March 11, 2024
Language: Английский
Nature Reviews Methods Primers, Journal Year: 2024, Volume and Issue: 4(1)
Published: May 30, 2024
Language: Английский
Citations
68
Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(33)
Published: April 21, 2023
Nanozymes, nanomaterials with enzyme-mimicking activity, have attracted tremendous interest in recent years owing to their ability replace natural enzymes various biomedical applications, such as biosensing, therapeutics, drug delivery, and bioimaging. In particular, the nanozymes capable of regulating cellular redox status by mimicking antioxidant mammalian cells are great therapeutic significance oxidative-stress-mediated disorders. As distinction physiological oxidative stress (oxidative eustress) pathological distress) occurs at a fine borderline, it is challenge design that can differentially sense two extremes cells, tissues organs mediate appropriate chemical reactions. this Review, we summarize advances development redox-active applications. We primarily highlight prooxidant disease model systems, cancer, neurodegeneration, cardiovascular diseases. The future perspectives emerging area research challenges associated applications described.
Language: Английский
Citations
61
BMEMat, Journal Year: 2023, Volume and Issue: unknown
Published: Sept. 19, 2023
Abstract Nanozymes have emerged as a promising alternative to natural enzymes, effectively addressing enzymes' inherent limitation. Versatility and potential applications of nanozyme span across various fields, with catalytic tumor therapy being one prominent area. This has sparked significant interest exploration in the utilization nanozymes for targeted cancer treatment. Recent advancements interdisciplinary research, nanotechnology, biotechnology, technology led emergence multi‐metallic‐based nanozymes, which exhibit tremendous further development. review focuses on investigating synergistic effects aiming enhance our understanding their activities facilitate broader applications. We comprehensively survey remarkable achievements synthesis, mechanisms, latest therapy. Furthermore, we identify current limitations prospects development new materials application novel technologies, along challenges associated underscores significance emphasizes need continued well impact realization breakthroughs
Language: Английский
Citations
48
Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 473, P. 145291 - 145291
Published: Aug. 7, 2023
Language: Английский
Citations
45
Nano Today, Journal Year: 2024, Volume and Issue: 54, P. 102142 - 102142
Published: Jan. 3, 2024
Language: Английский
Citations
30
Advanced Science, Journal Year: 2024, Volume and Issue: 11(17)
Published: Feb. 17, 2024
Abstract Atherosclerosis, a multifaceted chronic inflammatory disease, has profound impact on cardiovascular health. However, the critical limitations of atherosclerosis management include delayed detection advanced stages, intricate assessment plaque stability, and absence efficacious therapeutic strategies. Nanotheranostic based nanotechnology offers novel paradigm for addressing these challenges by amalgamating imaging capabilities with targeted interventions. Meanwhile, iron oxide nanoparticles have emerged as compelling candidates theranostic applications in due to their magnetic resonance capability biosafety. This review delineates current state prospects nanoparticle‐based nanotheranostics realm atherosclerosis, including pivotal aspects development, pertinent targeting strategies involved disease pathogenesis, diagnostic roles nanoparticles. Furthermore, this provides comprehensive overview nanomedicine approaches employing nanoparticles, encompassing chemical therapy, physical stimulation biological therapy. Finally, proposes discusses associated translating innovative into clinically viable anti‐atherosclerosis In conclusion, new insights future theranostic, showcasing remarkable potential oxide‐based versatile tools battle against atherosclerosis.
Language: Английский
Citations
17
Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 258, P. 116370 - 116370
Published: May 6, 2024
Language: Английский
Citations
17
Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 501, P. 215519 - 215519
Published: Dec. 1, 2023
Language: Английский
Citations
42
Nano Letters, Journal Year: 2023, Volume and Issue: 23(10), P. 4660 - 4668
Published: May 8, 2023
Oxidative stress is known to be the cause of several neurovascular diseases, including neurodegenerative disorders, since increase reactive oxygen species (ROS) levels can lead cellular damage, blood-brain barrier leaking, and inflammatory pathways. Herein, we demonstrate therapeutic potential 5 nm platinum nanoparticles (PtNPs) effectively scavenge ROS in different models unit. We investigated mechanism underlying PtNP biological activities, analyzing influence evolving environment during particle trafficking disclosing a key role protein corona, which elicited an effective switch-off catalytic properties, promoting their selective
Language: Английский
Citations
25
Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 12(3), P. 609 - 636
Published: Dec. 11, 2023
Cerium vanadate nanoparticles (CeVO
Language: Английский
Citations
23