Coffee or tea: Anti-inflammatory properties in the context of atherosclerotic cardiovascular disease prevention

Pharmacological Research, Journal Year: 2022, Volume and Issue: 187, P. 106596 - 106596

Published: Dec. 5, 2022

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of premature death worldwide. Inflammation and its biomarkers, like C-reactive protein (CRP), among risk factors, such as hypertension, lipid disorders, diabetes, may be also responsible for residual (CVD) risk. Modern lipid-lowering treatment with statins, ezetimibe, PCSK9 inhibitors, or bempedoic acid does not fully protect against inflammation. The recommendations International Lipid Expert Panel (ILEP) indicate selected nutraceuticals anti-inflammatory properties. Diet have a significant impact on Especially interesting in context inflammation consumption coffee tea. These drinks many observational studies significantly reduced mortality. question whether effects these contribute to observed clinical effects. Thus, this narrative review, we primarily discuss properties consuming tea coffee. Based comprehensive analysis their meta-analyses, inconsistent results were obtained, which makes it impossible conclusively state how clinically potential black green are. A number confounding factors can inconsistency available results. Consumption appears increase adiponectin concentrations, decrease reactive oxygen species, low density lipoprotein (LDL) cholesterol concentrations (effect tea, etc.). Despite still uncertain effect coffee, recommend part healthy diet.

Language: Английский

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Green synthesis by extraction of caffeine for cosmeceutical application: A review

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1305, P. 137733 - 137733

Published: Feb. 6, 2024

Language: Английский

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A longitudinal cohort study demonstrating the beneficial effect of moderate consumption of green tea and coffee on the prevention of dementia: The JPHC Saku Mental Health Study

Journal of Alzheimer s Disease, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Background While the preventive effects of green tea and coffee on cognitive decline have been demonstrated, their long-term cognition remain unclear. Objective This study aims to investigate effect consumption in middle age prevention dementia. Methods population-based cohort included 1155 participants (aged 44–66 1995). Participants’ was assessed using questionnaires 1995 2000. Their levels were neuropsychologically evaluated 2025–2015. Logistic regression analyses conducted with significant (defined as multi-domain more severe conditions) dependent variable. Stratified also by sex age. Results Individuals who consumed 2–3 cups daily had a significantly reduced risk (OR = 0.56, 95%CI: 0.35–0.91) after adjusting potential confounders. However, this not 4 or cups. protective particularly observed males 0.38, 0.19–0.76). A reduction individuals consuming one 0.54, 0.34–0.84) older subjects (median [53 years old] 1995) same fully adjusted model, but entire sample. Conclusions Our findings suggest that moderate midlife may beneficial preventing dementia, males. The be advantageous for individuals.

Language: Английский

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Non-pharmacological factors for hypertension management: a systematic review of international guidelines

European Journal of Preventive Cardiology, Journal Year: 2022, Volume and Issue: 30(1), P. 17 - 33

Published: Aug. 10, 2022

Lifestyle modifications are one of the cornerstones hypertension prevention and treatment. We aimed to systematically review guidelines on their recommendations non-pharmacological factors including lifestyle interventions, highlight strength evidence, similarities, differences. This systematic was registered with international Prospective Register Systematic Reviews (CRD42021288815). Publications in MEDLINE EMBASE databases over 10 years since January 2010 June 2020 were identified. also included search from websites organizations responsible for development. Two reviewers screened titles abstracts identify relevant guidelines. independently assessed rigour guideline development using AGREE II instrument, reviewer extracted recommendations. Of identified guidelines, showed good (AGREE ≥ 60%) review. The consistent most (reduced salt intake, weight, dietary patterns, increased physical activity smoking cessation, limiting alcohol intake). Some areas disagreement identified, regarding novel psychological environmental such as stress or air pollution, intake thresholds, meat, coffee tea consumption refined sugars. Current agree importance treatment hypertension. Consensus limited support integration management hypertensive patients public health measurements general population preventative measurements. Further research into role may help clarify future

Language: Английский

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Coffee Consumption and Risk of Hypertension in Adults: Systematic Review and Meta-Analysis

Nutrients, Journal Year: 2023, Volume and Issue: 15(13), P. 3060 - 3060

Published: July 7, 2023

Objectives: The association between coffee intake and hypertension (HTN) risk is controversial. Therefore, this systematic review meta-analysis aimed at summarizing the current evidence on of with in observational studies. Methods: PubMed/Medline Web Science were searched for studies up to February 2023. Observational which assessed HTN highest category consumption comparison lowest included (registration number: CRD42022371494). pooled effect was evaluated using a random-effects model. Results: Twenty-five i.e., thirteen cross-sectional twelve cohorts identified be eligible. Combining 13 extracted sizes from cohort showed that higher associated 7% reduction (95% CI: 0.88, 0.97; I2: 22.3%), whereas combining 16 illustrated greater (RR = 0.79, 95% 0.72, 0.87; I2 63.2%). These results varied by characteristics, such as region study, participants’ sex, study quality, sample size. Conclusions: An inverse found both However, dependent characteristics. Further considering factors are required confirm study.

Language: Английский

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Effect of coffee consumption on thyroid function: NHANES 2007-2012 and Mendelian randomization

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: June 7, 2023

Background Coffee is one of the most consumed beverages worldwide, but effects on thyroid are unknown. This study aims to examine association between coffee and function. Methods Participant data (≥ 20 years, n = 6578) for observational were obtained from NHANES 2007-2012. Analysis was performed using weighted linear regression models multiple logistic models. Genetic datasets Hyperthyroidism Hypothyroidism IEU database contained 462,933 European samples. Mendelian randomization (MR) used analysis, inverse variance weighting (IVW) main method analysis. Results In model adjusted other covariates, participants who drank 2-4 cups per day had significantly lower TSH concentrations compared non-coffee drinkers (b=-0.23, 95% CI: -0.30, -0.16), no statistically significant changes in TT4, FT4, TT3 FT3. addition, <2 showed a low risk developing subclinical hypothyroidism. (OR=0.60, 0.41, 0.88) Observational studies MR have demonstrated both that consumption has effect hyperthyroidism Conclusions Our drinking reduced hypothyroidism serum concentrations. not associated with

Language: Английский

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Association of caffeine consumption with all‐cause and cause‐specific mortality in adult Americans with hypertension

Food Science & Nutrition, Journal Year: 2024, Volume and Issue: 12(6), P. 4185 - 4195

Published: March 8, 2024

Abstract Coffee is an important beverage that widely consumed, of which caffeine the main active ingredient. However, long‐term relationship between consumption and mortality in hypertensive patients has rarely been studied. This study analyzed a cohort 12,093 US adults from National Health Nutrition Examination Survey 1999 to 2018. Caffeine was divided into five groups: no intake, >0 ≤100, >100 ≤300, >300 ≤400 >400 mg/day. Using multivariable‐adjusted Cox proportional hazards models, this performed 20‐year follow‐up analysis (1999–2018). In fully adjusted model, all consumers had lower all‐cause compared with especially mg/day group (hazard ratio (HR) 0.71, 95% confidence interval (CI) 0.60–0.84). The result restricted cubic spline also showed nonlinear association mortality. For cardiovascular disease, decreased only at (HR 0.63, CI 0.47–0.85). cancer, diabetes, kidney significantly associated mortality: 0.60, 0.42–0.67), 0.22, 0.07–0.75), 0.32, 0.10–0.96), respectively. Lower observed non‐Hispanic White, African American, population aged 40 or above, people body mass index <25 kg/m 2 . Our findings indicate average mortality, suggesting may benefit moderate intake.

Language: Английский

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Sustainable Utilization of Coffee Pulp, a By-Product of Coffee Production: Effects on Metabolic Syndrome in Fructose-Fed Rats

Antioxidants, Journal Year: 2025, Volume and Issue: 14(3), P. 266 - 266

Published: Feb. 25, 2025

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that include insulin resistance, impaired glucose tolerance, dyslipidemia, hypertension, and abdominal obesity. Coffee production generates large quantities waste products, which pose serious threat to the environment. However, coffee by-products, such as pulp (CP), possess an undeniable wealth bioactive components. Based on this, we investigated whether 10-week dietary intervention with 250 mg/kg/d CP could prevent or ameliorate MetS in high-fructose-fed rats. Consumption by rats fed high-fructose diet reduced body weight gain, lowered systolic blood pressure (SBP), fasting plasma levels, improved resistance compared alone. At hepatic level, attenuated increase lipid storage, peroxidation, glutathione levels when combined diet. also affected expression key genes related metabolism adipose tissues, fructose-rich This study demonstrates ameliorates several consequences high-fructose-induced rat (weight intolerance, changes liver, tissue function). Hence, our data provide evidence consumption context can be used improve management.

Language: Английский

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Yerba Mate (Ilex paraguariensis St. Hill.) Tea May Have Cardiometabolic Beneficial Effects in Healthy and At‐Risk Subjects: A Randomized, Controlled, Blind, Crossover Trial in Nonhabitual Consumers

Molecular Nutrition & Food Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

ABSTRACT Yerba mate has been reported to have antihypertensive, hypocholesterolemic, antidiabetic, or antiobesity properties. Most evidences from human trials involved intakes of high amounts by habitual consumers. Considering its increasing popularity, this study aimed at assessing the potential cardiometabolic effects moderate intake yerba nonhabitual A randomized, crossover, controlled was carried out in healthy and hypercholesterolemic subjects. Anthropometric parameters, blood pressure, lipids, glucose metabolism, inflammatory cytokines, chemokines, different markers endothelial function, as well incretins, adipocytokines, hormones were measured baseline after 8 weeks consuming a decaffeinated isotonic drink (control). After daily consumption three servings tea, colony‐stimulating factors decreased all participants. LDL‐C normocholesterolemic individuals, while control interventions elicited similar hypolipidemic action group. Ghrelin glucose‐dependent insulinotropic polypeptide (GIP) significantly intake, glucagon‐like peptide 1 (GLP‐1) adipocytokines remained unchanged. Body fat percentage tricipital skinfold only subjects, with no on total body weight. In conclusion, could exert protective consumers subjects cardiovascular risk. Trial Registration : This trial retrospectively registered ClinicalTrials (NCT06729905)

Language: Английский

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Association between coffee and caffeine intake and risk of COPD: Findings based on NHANES 2007–2012

Heart & Lung, Journal Year: 2024, Volume and Issue: 67, P. 53 - 61

Published: May 2, 2024

Language: Английский

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