Colloids and Surfaces B Biointerfaces,
Journal Year:
2022,
Volume and Issue:
214, P. 112455 - 112455
Published: March 11, 2022
Graphene
derivatives
such
as
reduced
graphene
oxide
(rGO)
are
used
components
of
novel
biomaterials
for
their
unique
electrical
properties.
Electrical
conductivity
is
a
crucial
factor
muscle
cells,
which
electrically
active.
This
study
reports
the
development
new
type
semi-interpenetrated
polymer
network
based
on
two
biodegradable
FDA-approved
biomaterials,
sodium
alginate
(SA)
and
polycaprolactone
(PCL),
with
Ca2+
ions
SA
crosslinker.
Several
drawbacks
low
cell
adhesion
weak
structural
stability
can
be
improved
incorporation
PCL.
Furthermore,
this
demonstrates
how
semi-IPN
engineered
rGO
nanosheets
(0.5%
2%
wt/wt
nanosheets)
to
produce
electroactive
nanohybrid
composite
biomaterials.
The
focuses
microstructure
enhancement
physical
biological
properties
these
advanced
materials,
including
water
sorption,
surface
wettability,
thermal
behavior
degradation,
mechanical
properties,
conductivity,
myogenic
differentiation.
results
suggest
formation
complex
nano-network
different
interactions
between
components:
bonds
chains
induced
by
(egg-box
model),
links
well
themselves
through
ions,
strong
hydrogen
bonding
chains.
significantly
increases
hydrogels,
values
in
range
tissue.
In
vitro
cultures
C2C12
murine
myoblasts
revealed
that
conductive
hydrogels
not
cytotoxic
greatly
enhance
myoblast
These
indicate
have
great
potential
biomedical
applications
related
regeneration
tissues,
particularly
skeletal
tissue
engineering.
Gels,
Journal Year:
2023,
Volume and Issue:
9(2), P. 100 - 100
Published: Jan. 23, 2023
Tissue
damage
and
organ
failure
are
major
problems
that
many
people
face
worldwide.
Most
of
them
benefit
from
treatment
related
to
modern
technology’s
tissue
regeneration
process.
engineering
is
one
the
booming
fields
widely
used
replace
damaged
tissue.
Scaffold
a
base
material
in
which
cells
growth
factors
embedded
construct
substitute
Various
materials
have
been
develop
scaffolds.
Bio-based
natural
biocompatible,
safe,
do
not
release
toxic
compounds
during
biodegradation.
Therefore,
it
highly
recommendable
fabricate
scaffolds
using
such
materials.
To
date,
there
no
singular
fulfill
all
features
scaffold.
Hence,
combining
two
or
more
encouraged
obtain
desired
characteristics.
design
reliable
scaffold
by
different
materials,
need
choose
good
fabrication
technique.
In
this
review
article,
bio-based
fine
techniques
currently
developing
for
applications,
along
with
number
articles
published
on
each
material,
briefly
discussed.
It
envisaged
gain
explicit
knowledge
applications.
Marine Drugs,
Journal Year:
2023,
Volume and Issue:
21(3), P. 189 - 189
Published: March 18, 2023
Today,
with
the
salient
advancements
of
modern
and
smart
technologies
related
to
tissue
engineering
regenerative
medicine
(TE-RM),
use
sustainable
biodegradable
materials
biocompatibility
cost-effective
advantages
have
been
investigated
more
than
before.
Alginate
as
a
naturally
occurring
anionic
polymer
can
be
obtained
from
brown
seaweed
develop
wide
variety
composites
for
TE,
drug
delivery,
wound
healing,
cancer
therapy.
This
renewable
biomaterial
displays
several
fascinating
properties
such
high
biocompatibility,
low
toxicity,
cost-effectiveness,
mild
gelation
by
inserting
divalent
cations
(e.g.,
Ca2+).
In
this
context,
challenges
still
exist
in
relation
solubility
viscosity
high-molecular
weight
alginate,
density
intra-
inter-molecular
hydrogen
bonding,
polyelectrolyte
nature
aqueous
solution,
lack
suitable
organic
solvents.
Herein,
TE-RM
applications
alginate-based
are
deliberated,
focusing
on
current
trends,
important
challenges,
future
prospects.
Bioactive Materials,
Journal Year:
2023,
Volume and Issue:
28, P. 511 - 536
Published: June 27, 2023
Bioinks
are
formulations
of
biomaterials
and
living
cells,
sometimes
with
growth
factors
or
other
biomolecules,
while
extrusion
bioprinting
is
an
emerging
technique
to
apply
deposit
these
bioinks
biomaterial
solutions
create
three-dimensional
(3D)
constructs
architectures
mechanical/biological
properties
that
mimic
those
native
human
tissue
organs.
Printed
have
found
wide
applications
in
engineering
for
repairing
treating
tissue/organ
injuries,
as
well
vitro
modelling
testing
validating
newly
developed
therapeutics
vaccines
prior
their
use
humans.
Successful
printing
subsequent
rely
on
the
formulated
bioinks,
including
rheological,
mechanical,
biological
properties,
process.
This
article
critically
reviews
latest
developments
bioprinting,
focusing
bioink
synthesis
characterization,
influence
Key
issues
challenges
also
discussed
along
recommendations
future
research.
Materials Advances,
Journal Year:
2022,
Volume and Issue:
3(4), P. 1849 - 1873
Published: Jan. 1, 2022
Preparation,
characterization
and
applications,
particularly
for
signal-stimulated
molecule
release,
of
Fe
3+
-cross-linked
alginate
hydrogels
are
critically
overviewed.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(2), P. 464 - 464
Published: Feb. 21, 2022
Skin
tissue
engineering
and
regeneration
aim
at
repairing
defective
skin
injuries
progress
in
wound
healing.
Until
now,
even
though
several
developments
are
made
this
field,
it
is
still
challenging
to
face
the
complexity
of
with
current
methods
fabrication.
In
review,
short,
state-of-the-art
on
using
3D
bioprinting
as
a
new
tool
described.
The
summary
bioink
formulations,
parameters,
properties
discussed.
Finally,
representative
number
examples
advances
field
together
limitations
future
needs
provided.
Journal of Biomedical Materials Research Part B Applied Biomaterials,
Journal Year:
2022,
Volume and Issue:
111(1), P. 220 - 233
Published: Aug. 12, 2022
The
skin
is
the
largest
organ
in
human
body
and
its
physical
integrity
must
be
maintained
for
homeostasis
to
prevent
entry
of
pathogenic
microorganisms.
Sodium
alginate
(SA)
polyvinyl
alcohol
(PVA)
are
two
polymers
widely
used
films
wound
dressing
applications.
Furthermore,
blends
between
SA
PVA
improve
physical,
mechanical
biological
properties
final
healing
material
when
compared
individual
polymers.
Different
drugs
have
been
incorporated
into
SA/PVA-based
activity.
It
noteworthy
that
SA/PVA
can
crosslinked
with
Ca2+
or
other
agents,
which
improves
physicochemical
properties.
Thus,
associations
promising
biomedical
field,
as
a
potential
alternative
treatment.
This
review
focuses
on
main
techniques
obtaining
films,
their
physical-chemical
characterization,
drug
incorporation,
advantages
challenges
these
healing.
