Materials,
Journal Year:
2019,
Volume and Issue:
12(2), P. 277 - 277
Published: Jan. 16, 2019
The
flexibility
in
polymer
properties
has
allowed
the
development
of
a
broad
range
materials
with
electroactivity,
such
as
intrinsically
conductive
conjugated
polymers,
percolated
composites,
and
ionic
hydrogels.
These
smart
electroactive
polymers
can
be
designed
to
respond
rationally
under
an
electric
stimulus,
triggering
outstanding
suitable
for
biomedical
applications.
This
review
presents
general
overview
potential
applications
these
field
tissue
engineering
biomaterials.
In
particular,
details
about
ability
to:
(1)
stimulate
cells
context
by
providing
electrical
current;
(2)
mimic
muscles
converting
energy
into
mechanical
through
electromechanical
response;
(3)
deliver
drugs
changing
their
internal
configuration
stimulus;
(4)
have
antimicrobial
behavior
due
conduction
electricity,
are
discussed.
Advanced Healthcare Materials,
Journal Year:
2021,
Volume and Issue:
10(16)
Published: June 26, 2021
Abstract
The
universal
increase
in
the
number
of
patients
with
nonhealing
skin
wounds
imposes
a
huge
social
and
economic
burden
on
healthcare
systems.
Although,
application
traditional
wound
dressings
contributes
to
an
effective
healing
outcome,
yet,
complexity
process
remains
major
health
challenge.
Recent
advances
materials
fabrication
technologies
have
led
that
provide
proper
conditions
for
healing.
3D‐printed
dressings,
biomolecule‐loaded
as
well
smart
flexible
bandages
are
among
recent
alternatives
been
developed
accelerate
Additionally,
new
generation
contains
variety
microelectronic
sensors
real‐time
monitoring
environment
is
able
apply
required
actions
support
progress.
Moreover,
manufacturing
enable
development
next
dressing
substrates,
known
electronic
skin,
whole
physiochemical
markers
single
platform.
current
study
reviews
importance
emerging
strategy
care
management
highlights
different
types
promoting
process.
Advanced Healthcare Materials,
Journal Year:
2020,
Volume and Issue:
9(9)
Published: March 20, 2020
There
is
urgency
for
the
development
of
nanomaterials
that
can
meet
emerging
biomedical
needs.
Magnetic
nanoparticles
(MNPs)
offer
high
magnetic
moments
and
surface-area-to-volume
ratios
make
them
attractive
hyperthermia
therapy
cancer
targeted
drug
delivery.
Additionally,
they
function
as
contrast
agents
resonance
imaging
(MRI)
improve
sensitivity
biosensors
diagnostic
tools.
Recent
advancements
in
nanotechnology
have
resulted
realization
next
generation
MNPs
suitable
these
other
applications.
This
review
discusses
methods
utilized
fabrication
engineering
MNPs.
progress
use
therapy,
controlling
release,
MRI,
biosensing
also
critically
reviewed.
Finally,
challenges
field
potential
opportunities
toward
improving
their
properties
are
discussed.
Small,
Journal Year:
2018,
Volume and Issue:
14(33)
Published: July 6, 2018
Abstract
Chronic
wounds
are
a
major
health
concern
and
they
affect
the
lives
of
more
than
25
million
people
in
United
States.
They
susceptible
to
infection
leading
cause
nontraumatic
limb
amputations
worldwide.
The
wound
environment
is
dynamic,
but
their
healing
rate
can
be
enhanced
by
administration
therapies
at
right
time.
This
approach
requires
real‐time
monitoring
with
on‐demand
drug
delivery
closed‐loop
manner.
In
this
paper,
smart
automated
flexible
dressing
temperature
pH
sensors
integrated
onto
bandages
that
monitor
status
address
unmet
medical
need
presented.
Moreover,
stimuli‐responsive
releasing
system
comprising
hydrogel
loaded
thermo‐responsive
carriers
an
electronically
controlled
heater
also
into
release
drugs
on‐demand.
equipped
microcontroller
process
data
measured
program
protocol
for
individualized
treatment.
has
potential
significantly
impact
treatment
chronic
wounds.
Pharmaceutics,
Journal Year:
2020,
Volume and Issue:
12(12), P. 1188 - 1188
Published: Dec. 7, 2020
Owing
to
their
tunable
properties,
controllable
degradation,
and
ability
protect
labile
drugs,
hydrogels
are
increasingly
investigated
as
local
drug
delivery
systems.
However,
a
lack
of
standardized
methodologies
used
characterize
evaluate
release
poses
significant
difficulties
when
comparing
findings
from
different
investigations,
preventing
an
accurate
assessment
Here,
we
review
the
commonly
analytical
techniques
for
detection
quantification
hydrogel
The
experimental
conditions
in
saline
solutions
impact
discussed,
along
with
main
mathematical
statistical
approaches
profiles.
We
also
methods
determine
diffusion
coefficients
vitro
vivo
models
assess
efficacy
goal
provide
guidelines
harmonized
practices
investigating
novel
Advanced Healthcare Materials,
Journal Year:
2020,
Volume and Issue:
10(1)
Published: Oct. 18, 2020
Abstract
Injectable
hydrogels
have
received
considerable
interest
in
the
biomedical
field
due
to
their
potential
applications
minimally
invasive
local
drug
delivery,
more
precise
implantation,
and
site‐specific
delivery
into
poorly
reachable
tissue
sites
interface
tissues,
where
wound
healing
takes
a
long
time.
hydrogels,
such
as
situ
forming
and/or
shear‐thinning
can
be
generated
using
chemically
physically
crosslinked
hydrogels.
Yet,
for
controlled
applications,
ideal
injectable
hydrogel
should
able
provide
sustained
release
of
molecules
target
site
when
needed
limit
nonspecific
molecule
distribution
healthy
tissues.
Thus,
sense
environmental
changes
that
arise
disease
states
optimal
amount
over
necessary
time
period
region.
To
address
this,
researchers
designed
stimuli‐responsive
Stimuli‐responsive
change
shape
or
volume
they
stimuli,
e.g.,
pH,
temperature,
light,
electrical
signals,
enzymatic
changes,
deliver
an
concentration
drugs
without
affecting
