The green office environment: New Zealand workers' perception of IEQ DOI Creative Commons
Eziaku Onyeizu Rasheed, James Olabode Bamidele Rotimi

Smart and Sustainable Built Environment, Journal Year: 2022, Volume and Issue: 13(5), P. 1240 - 1259

Published: Dec. 28, 2022

Purpose Achieving an appropriate indoor environment quality (IEQ) is crucial to a green office environment. Whilst much research has been carried out across the globe on ideal IEQ for offices, little known about which New Zealand workers prefer and regard as most appropriate. This study investigated workers' preference Design/methodology/approach Workers were conveniently selected questionnaire survey from two major cities in country – Wellington Auckland. The perception of 149 was analysed discussed based demographics. responses each question mean, standard deviation, frequency difference opinion. Findings results showed that preferences work environments depend largely have more fresh air rely mixed-mode ventilation lighting systems. Also like better acoustic with less distraction background noise. Regarding temperature, workspaces be neither cooler nor warmer. Unique workers, some (not complete) individual control over offices. Research limitations/implications conducted summer season, could impacted received. sample size limited country. Further studies should other regions during different seasons. Practical implications provides opportunity this area highlights significant findings worthy critical investigations. benefit various stakeholders, such facilities managers workplace designers, support proactive response approaches achieving building occupants' Originality/value first explore worker not particular building, expanding body knowledge

Language: Английский

Bacterial enzymatic degradation of recalcitrant organic pollutants: catabolic pathways and genetic regulations DOI

Swetambari Kumari,

Surajit Das

Environmental Science and Pollution Research, Journal Year: 2023, Volume and Issue: 30(33), P. 79676 - 79705

Published: June 17, 2023

Language: Английский

Citations

50
The Role of Endocrine Disruptors Bisphenols and Phthalates in Obesity: Current Evidence, Perspectives and Controversies DOI Open Access
Μaria Dalamaga,

Dimitrios Kounatidis,

Dimitrios Tsilingiris

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(1), P. 675 - 675

Published: Jan. 4, 2024

Excess body weight constitutes one of the major health challenges for societies and healthcare systems worldwide. Besides type diet, calorie intake lack physical exercise, recent data have highlighted a possible association between endocrine-disrupting chemicals (EDCs), such as bisphenol A, phthalates their analogs, obesity. EDCs represent heterogeneous group that may influence hormonal regulation mass adipose tissue morphology. Based on available from mechanistic, animal epidemiological studies including meta-analyses, evidence points towards contribution to development obesity, associated disorders obesity-related dysfunction by (1) impacting adipogenesis; (2) modulating epigenetic pathways during development, enhancing susceptibility obesity; (3) influencing neuroendocrine signals responsible appetite satiety; (4) promoting proinflammatory milieu in inducing state chronic subclinical inflammation; (5) dysregulating gut microbiome immune homeostasis; (6) thermogenic tissue. Critical periods exposure obesogenic are prenatal, neonatal, pubertal reproductive periods. Interestingly, even at low doses promote transgenerational inheritance adult obesity subsequent generations. The aim this review is summarize role EDCs, specifically BPA phthalate plasticizers, taking into account vitro, epidemiologic studies; discuss mechanisms linking analyze effects critical exposure; present interesting perspectives, preventive measures research area.

Language: Английский

Citations

41
Room-temperature preparation of highly efficient NH2-MIL-101(Fe) catalyst: The important role of –NH2 in accelerating Fe(III)/Fe(II) cycling DOI

Peipei Huang,

Lili Yao, Qing Chang

et al.

Chemosphere, Journal Year: 2021, Volume and Issue: 291, P. 133026 - 133026

Published: Nov. 22, 2021

Language: Английский

Citations

82
Endocrine Disrupting Chemicals’ Effects in Children: What We Know and What We Need to Learn? DOI Open Access
Barbara Predieri, Lorenzo Iughetti, Sergio Bernasconi

et al.

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(19), P. 11899 - 11899

Published: Oct. 7, 2022

Thousands of natural or manufactured chemicals were defined as endocrine-disrupting (EDCs) because they can interfere with hormone activity and the endocrine system. We summarize discuss what we know still need to learn about EDCs' pathogenic mechanisms action, well effects most common EDCs on system health in childhood. The MEDLINE database (PubMed) was searched 13 May 2022, filtering for EDCs, diseases, children. are a group compounds high heterogeneity, but usually disrupt by mimicking interfering hormones body's hormonal balance through other mechanisms. Individual studied detail, while humans' "cocktail effect" is unclear. In utero, early postnatal life, and/or pubertal development highly susceptible periods exposure. Human epidemiological studies suggest that affect prenatal growth, thyroid function, glucose metabolism, obesity, puberty, fertility several Further needed clarify which mainly act epigenetic processes. A better understanding human crucial developing future regulatory strategies prevent exposure ensure children today, generations, environment.

Language: Английский

Citations

47
Fetal programming: could intrauterin life affect health status in adulthood? DOI Creative Commons
Hande Nur Onur Öztürk, Perim Fatma Türker

Obstetrics & Gynecology Science, Journal Year: 2021, Volume and Issue: 64(6), P. 473 - 483

Published: Oct. 20, 2021

Intrauterine life is one of the most important periods life. As development fetus continues, mechanisms that affect adult health also begin to mature. With hypothesis denoted "fetal programming," it thought presence endocrinological disorders, toxins, infectious agents, nutritional status a mother, and nutrients related placental functionality all have an effect on future Therefore, must adapt environment for survival. These adaptations may be involved redistribution metabolic, hormonal, or cardiac outputs in effort protect brain, which organs, as well slowing growth meet requirements. Unlike lifestyle changes treatments received life, early developmental period tends lasting structure body. In this review, fetal programming effects are discussed.

Language: Английский

Citations

44
Evaluating Phthalates and Bisphenol in Foods: Risks for Precocious Puberty and Early-Onset Obesity DOI Open Access
Valeria Calcaterra, Hellas Cena, Federica Loperfido

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(16), P. 2732 - 2732

Published: Aug. 16, 2024

Recent scientific results indicate that diet is the primary source of exposure to endocrine-disrupting chemicals (EDCs) due their use in food processing, pesticides, fertilizers, and migration from packaging food, particularly plastic or canned foods. Although EDCs are not listed on nutrition labels, could inadvertently lead contamination, affecting individuals by inhalation, ingestion, direct contact. The aim our narrative review investigate role phthalates bisphenol A (BPA) foods, assessing risks for precocious puberty (PP) early-onset obesity, which two clinical entities often associated share common pathogenetic mechanisms. diverse outcomes observed across different studies highlight complexity BPA effects human body, both terms early puberty, girls, obesity with its metabolic disruptions. Moreover, independently linked might confound relationship between these pubertal timing. Given potential public health implications, it crucial adopt a precautionary approach, minimizing EDCs, especially vulnerable populations such as children.

Language: Английский

Citations

7
Bioremediation of Endocrine Disrupting Chemicals- Advancements and Challenges DOI
Sherly Antony,

Sham Antony,

Sharrel Rebello

et al.

Environmental Research, Journal Year: 2022, Volume and Issue: 213, P. 113509 - 113509

Published: June 3, 2022

Language: Английский

Citations

28
Reduced Birth Weight and Exposure to Per- and Polyfluoroalkyl Substances: A Review of Possible Underlying Mechanisms Using the AOP-HelpFinder DOI Creative Commons
Claudia Gundacker, Karine Audouze, Raimund Widhalm

et al.

Toxics, Journal Year: 2022, Volume and Issue: 10(11), P. 684 - 684

Published: Nov. 12, 2022

Prenatal exposure to per- and polyfluorinated substances (PFAS) may impair fetal growth. Our knowledge of the underlying mechanisms is incomplete. We used Adverse Outcome Pathway (AOP)-helpFinder tool search PubMed for studies published until March 2021 that examined PFAS in relation birth weight, oxidative stress, hormones/hormone receptors, or growth signaling pathways. Of these 1880 articles, 106 experimental remained after abstract screening. One clear finding are associated with stress vivo animal vitro studies. It appears PFAS-induced reactive-oxygen species (ROS) generation triggers increased peroxisome proliferator-activated receptor (PPAR)γ expression activation pathways, leading hyperdifferentiation pre-adipocytes. Fewer proliferating pre-adipocytes result lower adipose tissue weight this way reduce weight. also through endocrine effects. Estrogenic effects have been noted Overall, data suggest thyroid-damaging affecting thyroid hormones, hormone gene expression, histology decreased body organ The on complex relationships between system function, adipogenesis, should be further explored.

Language: Английский

Citations

26
Iodine as a potential endocrine disruptor—a role of oxidative stress DOI Creative Commons
Małgorzata Karbownik‐Lewińska, Jan Stępniak,

Paulina Iwan

et al.

Endocrine, Journal Year: 2022, Volume and Issue: 78(2), P. 219 - 240

Published: June 20, 2022

Iodine is an essential micronutrient required for thyroid hormone biosynthesis. However, overtreatment with iodine can unfavorably affect physiology. The aim of this review to present the evidence that iodine-when in excess-can interfere synthesis and, therefore, act as a potential endocrine-disrupting chemical (EDC), and action, well other abnormalities thyroid, occurs-at least partially-via oxidative stress.We reviewed published studies on EDC, particular emphasis phenomenon stress.This paper summarizes current knowledge excess context its properties EDC effects processes.Iodine does fulfill criteria because it exogenous interferes-when excess-with synthesis. statement cannot change general rules regarding supply, which means deficiency should be still eliminated worldwide at same time, avoided. Universal awareness would make consumers more careful their diet what they supplement tablets, and-what great importance-it caregivers choose iodine-containing medications (or chemicals) prudently. It stressed compared deficiency, (acting either or via mechanisms) much less harmful such sense affects only small percentage sensitive individuals, whereas former whole populations; causes endemic consequences.

Language: Английский

Citations

23
Effects of BPA substitutes on the prenatal and cardiovascular systems DOI
Fatima Abrantes-Soares, Margarida Lorigo, Elisa Cairrão

et al.

Critical Reviews in Toxicology, Journal Year: 2022, Volume and Issue: 52(6), P. 469 - 498

Published: July 3, 2022

Bisphenol A (BPA) is a ubiquitous chemical compound constantly being released into the environment, making it one of most persistent endocrine-disrupting (EDC) in nature. This EDC has already been associated with developing various pathologies, such as diabetes, obesity, and cardiovascular, renal, behavioral complications, among others. Therefore, over years, BPA replaced, gradually, by its analog compounds. However, these compounds are structurally similar to BPA, so, recent questions have raised concerning their safety for human health. Numerous investigations performed determine effects substitutes may cause, particularly during pregnancy prenatal life. On other hand, studies investigating association development cardiovascular diseases (CVD) developed. In this sense, review summarizes existing literature on transgenerational transfer consequent maternal offspring health following exposure. addition, compounds’ system susceptibility develop CVD will be presented. aims highlight need investigate further benefits, or hazards, replacing analogs.

Language: Английский

Citations

23