Recent Advances in Dual‐Function Superhydrophobic Antibacterial Surfaces DOI

Dongxu Jia,

Yuancheng Lin, Yi Zou

et al.

Macromolecular Bioscience, Journal Year: 2023, Volume and Issue: 23(11)

Published: June 2, 2023

Abstract Bacterial adhesion and subsequent biofilm formation on the surfaces of synthetic materials imposes a significant burden in various fields, which can lead to infections patients or reduce service life industrial devices. Therefore, there is increasing interest imbuing with antibacterial properties. Bioinspired superhydrophobic high water contact angles (>150°) exhibit excellent surface repellency against contaminations, thereby preventing initial bacterial inhibiting formation. However, conventional typically lack long‐term durability are incapable achieving persistent efficacy adhesion. To overcome these limitations, recent decades, dual‐function both bacteria‐repelling bacteria‐killing properties have been developed by introducing bactericidal components. These demonstrated improved performance addressing issues associated surface‐attached bacteria. This review summarizes advancements surfaces. First, brief overview fabrication strategies mechanism provided then classified into three types based mechanism: i) mechanotherapy, ii) chemotherapy, iii) phototherapy. Finally, limitations challenges current research discussed future perspectives this promising area proposed.

Language: Английский

Development of organic photosensitizers for antimicrobial photodynamic therapy DOI
Wenya Zhou, Xiqun Jiang, Zhen Xu

et al.

Biomaterials Science, Journal Year: 2023, Volume and Issue: 11(15), P. 5108 - 5128

Published: Jan. 1, 2023

This review mainly summarises the recent progress in development of organic photosensitizers, including porphyrins, chlorophyll, phenothiazines, xanthenes and aggregation-induced emission for antimicrobial photodynamic therapy.

Language: Английский

Citations

38
The Role of Hydrogel in Cardiac Repair and Regeneration for Myocardial Infarction: Recent Advances and Future Perspectives DOI Creative Commons
Ping Li, Jiajia Hu, Jian Wang

et al.

Bioengineering, Journal Year: 2023, Volume and Issue: 10(2), P. 165 - 165

Published: Jan. 27, 2023

A myocardial infarction (MI) is the leading cause of morbidity and mortality, seriously threatens human health, becomes a major health burden our society. It urgent to pursue effective therapeutic strategies for regeneration restore function after MI. This review discusses role hydrogel in cardiac repair Hydrogel-based patches injectable hydrogels are most commonly used applications medicine. With hydrogels, bioactive compounds cells can be delivered situ, promoting situ regeneration, while hydrogel-based reduce wall stress, which passively inhibits ventricular expansion. work as mechanically supportive biomaterials. In medicine, clinical trials commercial products limited. Biomaterials, biochemistry, biological actives, such intelligent exosome patches, may serve an treatment MI future, still under development. Further investigation feasibility warranted. We anticipate having immense translational potential near future.

Language: Английский

Citations

29
Medical Applications and Advancement of Near Infrared Photosensitive Indocyanine Green Molecules DOI Creative Commons

Zulpya Mahmut,

Chunmei Zhang, Fei Ruan

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(16), P. 6085 - 6085

Published: Aug. 16, 2023

Indocyanine green (ICG) is an important kind of near infrared (NIR) photosensitive molecules for PTT/PDT therapy as well imaging. When exposed to NIR light, ICG can produce reactive oxygen species (ROS), which kill cancer cells and pathogenic bacteria. Moreover, the absorbed light also be converted into heat by eliminate cells. In addition, it performs exceptionally in optical imaging-guided tumor antimicrobial due its deeper tissue penetration low photobleaching properties near-infrared region compared other dyes. order solve problems water stability multi-function problem molecules, composite nanomaterials based on have been designed widely used, especially fields tumors sterilization. So far, their materials become one most famous sensitive materials. However, there no corresponding review articles focused molecules. this review, molecular structure ICG, material design, light- triggered anti-tumor, antibacterial, clinical applications are reviewed detail, great significance related research.

Language: Английский

Citations

29
ROS‐Responsive Core‐Shell Microneedles Based on Simultaneous Efficient Type I/II Photosensitizers for Photodynamic Against Bacterial Biofilm Infections DOI
Hongxue Li, Xiuli Zheng,

Zekun Gao

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: June 14, 2024

Abstract Antimicrobial photodynamic therapy (aPDT) has emerged as an appealing therapeutic option against biofilm infections. However, effectively penetrating the dense barrier of and anchoring bacteria to achieve elimination wound healing under hypoxic environments remains a challenge for aPDT. Herein, three type I/II Hypocrellin B (HB)‐cationic photosensitizers (HB‐P, HB‐TP, HB‐TTP) are designed based on multi‐cationic long chains molecular engineering strategy. With increasing number introduced cations, reactive oxygen species (ROS) production bacterial‐anchoring abilities HB‐cationic greatly enhanced. Notably, HB‐TTP demonstrates higher aPDT activity broad‐spectrum antibacterial properties. Furthermore, address conundrum biofilm‐infected wounds, ROS‐responsive core‐shell microneedle (HB‐TTP&EGF@MN) is by biphasically integrating growth factor. When penetrates biofilm, shell quickly dissolves releases removal laser irradiation. The core subsequently degraded slowly in presence endogenous ROS within wound, facilitating sustained release factor promote tissue regeneration. This work not only provides effective strategy rational design efficient antimicrobial agents but also proposes innovative ideas development controlled‐release pharmaceutical materials synergize

Language: Английский

Citations

15
Functional nanomaterials as photosensitizers or delivery systems for antibacterial photodynamic therapy DOI

Ruijiao Yan,

Meijun Zhan,

Jingchen Xu

et al.

Biomaterials Advances, Journal Year: 2024, Volume and Issue: 159, P. 213820 - 213820

Published: Feb. 28, 2024

Language: Английский

Citations

12
Crown-ether threaded covalent organic polyrotaxane framework (COPF) towards synergistic crown/Zn2+/photothermal/photodynamic antibacterial and infected wound healing therapy DOI
Shaoyu Wang, Jing Zhang,

Lichao Chu

et al.

Biomaterials Advances, Journal Year: 2024, Volume and Issue: 159, P. 213814 - 213814

Published: Feb. 26, 2024

Language: Английский

Citations

11
Advancements of Porphyrin‐Derived Nanomaterials for Antibacterial Photodynamic Therapy and Biofilm Eradication DOI Open Access
Suwen Chen,

Baoxuan Huang,

Jia Tian

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(27)

Published: July 27, 2024

Abstract The threat posed by antibiotic‐resistant bacteria and the challenge of biofilm formation has highlighted inadequacies conventional antibacterial therapies, leading to increased interest in photodynamic therapy (aPDT) recent years. This approach offers advantages such as minimal invasiveness, low systemic toxicity, notable effectiveness against drug‐resistant bacterial strains. Porphyrins their derivatives, known for high molar extinction coefficients singlet oxygen quantum yields, have emerged crucial photosensitizers aPDT. However, practical application is hindered challenges poor water solubility aggregation‐induced quenching. To address these limitations, extensive research focused on development porphyrin‐based nanomaterials aPDT, enhancing efficacy sterilization broadening range antimicrobial activity. review provides an overview various utilized aPDT eradication years, including porphyrin‐loaded inorganic nanoparticles, polymer assemblies, supramolecular metal–organic frameworks (MOFs), covalent organic (COFs). Additionally, insights into prospects offered, highlighting its potential implementation.

Language: Английский

Citations

11
Light-Activated Nanofibers: Advances in Photo-Responsive Electrospun Polymer Technologies DOI

Elyas Sharif Bakhsh,

Masoud Tavakoli Dare, Aliakbar Jafari

et al.

Polymer-Plastics Technology and Materials, Journal Year: 2024, Volume and Issue: 64(4), P. 397 - 438

Published: Oct. 1, 2024

Language: Английский

Citations

11
A one-step polyphenol-based functionalization strategy of dual-enhanced antibacterial and osteogenic surfaces DOI
Xiao Chen,

Meizhou Sun,

Lujiao Zhang

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 490, P. 151792 - 151792

Published: April 29, 2024

Language: Английский

Citations

8
Covalent Organic Framework: A Rising Star in Antibacterial Agents DOI Open Access

Luo‐Gang Ding,

Minmin Shi, Yulin Xu

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

Abstract In the face of escalating antibiotic resistance crisis, world is embroiled in a silent “antibacterial war”. Scientists are actively searching for innovative antibacterial materials that can be used as effective weapons against bacterial infections. As promising new crystalline porous polymer materials, covalent organic frameworks (COFs) gradually revealing their vast potential applications. This study investigates classification COF‐based agents, provides comprehensive overview applications and research advancements, explores strategies employed by COF materials. Furthermore, challenges outlined lie ahead future application agents insights into prospects within field offered. Through these efforts, aim to accelerate advancements COFs manufacturing technology, promote innovation applications, contribute public health.

Language: Английский

Citations

1