Soft Matter, Journal Year: 2024, Volume and Issue: 20(19), P. 4021 - 4034
Published: Jan. 1, 2024
A new 3D bioprinted biomaterial, with flax fiber-reinforced alginate hydrogel, is developed. The study assesses the impact of fibers on printing, mechanical, 4D and geometric properties composite.
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 255, P. 128198 - 128198
Published: Nov. 20, 2023
Language: Английский
Citations
41
International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 258, P. 128917 - 128917
Published: Dec. 20, 2023
Language: Английский
Citations
33
Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 334, P. 122045 - 122045
Published: March 14, 2024
Language: Английский
Citations
15
Advanced Science, Journal Year: 2024, Volume and Issue: 11(47)
Published: Nov. 18, 2024
Abstract Skin wounds have become an important issue that affects human health and burdens global medical care. Hydrogel materials similar to the natural extracellular matrix (ECM) are one of best candidates for ideal wound dressings most feasible choices printing inks. Distinct from hydrogels made by traditional technologies, which lack bionic mechanical properties, 3D can promptly accurately create with complex bioactive structures potential promote tissue regeneration healing. Herein, a comprehensive review multi‐functional printing‐based hydrogel healing is presented. The first summarizes techniques dressings, including photo‐curing, extrusion, inkjet, laser‐assisted printing. Then, properties design approaches series bioinks composed natural, synthetic, composite polymers described. Thereafter, application in variety environments discussed depth, hemostasis, anti‐inflammation, antibacterial, skin appendage regeneration, intelligent monitoring, machine learning‐assisted therapy. Finally, challenges prospects
Language: Английский
Citations
14
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 264, P. 130593 - 130593
Published: March 2, 2024
Language: Английский
Citations
13
Heliyon, Journal Year: 2024, Volume and Issue: 10(19), P. e38497 - e38497
Published: Sept. 26, 2024
Language: Английский
Citations
13
View, Journal Year: 2024, Volume and Issue: 5(4)
Published: July 18, 2024
Abstract With the aging and obesity era, increasing incidence of diabetes diabetic complications, especially non‐healing wounds, imposes a serious economic burden on both patients society. The complex microenvironments, including hyperglycemia, bacterial infection, ischemia, nerve damage, lead to prolonged inflammation proliferation phase wounds. Mesenchymal stem cell‐derived small extracellular vesicles (MSC‐sEVs), which contain rich variety therapeutic molecules, have been chased for decades because their potential roles in cellular communication, tissue regeneration, drug delivery. As powerful tools controlled‐sustained release sEVs, biocompatible hydrogels applied wide range biomedical applications. Herein, we first summarize pathological features such as angiopathy, neuropathy, immune cell dysfunction. Then, discuss biological properties, performance, stability pure MSC‐sEVs. After that, components, application patterns, responsiveness hydrogels. Next, loading avenues MSC‐sEVs into hydrogel, behaviors sEVs from hydrogels, influence crosslinking method hydrogel‐sEV composites. Finally, provide an overview current applications loaded with novel cell‐free engineering system managing wounds propose critical unsolved issues. This review is expected meaningful guidance developing wound management.
Language: Английский
Citations
10
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 30, 2024
Abstract Wound management has always been a challenge in the clinical treatment of diabetes. In this study, glucose oxidase (GOx) is grafted onto natural pullulan polysaccharides, and oxidization carried out to form self‐healing hydrogel using carboxymethyl chitosan by means reversible Schiff base covalent bonding. The smart‐response drug release properties are demonstrated diabetic wounds taking advantage two key factors, namely pH‐responsive nature bonding fact that GOx reduces pH wounds. To further enhance biological functions dressing, exosomes (Exos) introduced into system. present system improves high‐glucose microenvironment wounds, releasing H 2 O impart antimicrobial effects, ensuring realizes function. component used construct plays an effective antibacterial role. Moreover, Exos loaded effectively promotes neovascularization wound. also regulates macrophage polarization levels persistent inflammation These results suggest smart responsive, multifunctional, dressing ideal for
Language: Английский
Citations
10
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(3), P. 1525 - 1525
Published: Jan. 26, 2024
Platelet concentrates such as platelet-rich plasma, fibrin or concentrated growth factors are cost-effective autologous preparations containing various factors, including platelet-derived factor, transforming factor β, insulin-like 1 and vascular endothelial factor. For this reason, they often used in regenerative medicine to treat wounds, nerve damage well cartilage bone defects. Unfortunately, after administration, these release very quickly, which lose their activity rapidly. As a consequence, results the need repeat therapy, is associated with additional pain discomfort for patient. Recent research shows that combining platelet biomaterials overcomes problem because released more sustainable manner. Moreover, concept fits into latest trends tissue engineering, include biomaterials, bioactive cells. Therefore, review presents literature reports on properties of enriched applications skin, nerve, engineering.
Language: Английский
Citations
9
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 280, P. 136214 - 136214
Published: Oct. 1, 2024
Language: Английский
Citations
9