Journal of Materials Research and Technology, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(9), P. 4490 - 4606
Published: Jan. 1, 2024
This review discusses recent advances, challenges, future research directions and perspectives in biomineralized tissues, providing in-depth insights into derived guidelines for design preparation of high-performance biomimetic materials.
Language: Английский
Citations
31
Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials, Journal Year: 2024, Volume and Issue: 151, P. 106391 - 106391
Published: Jan. 9, 2024
Language: Английский
Citations
20
Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(1), P. 93 - 93
Published: Jan. 10, 2024
Wounds and chronic wounds can be caused by bacterial infections lead to discomfort in patients. To solve this problem, scientists are working create modern wound dressings with antibacterial additives, mainly because traditional materials cannot meet the general requirements for complex promote healing. This demand is met material engineering, through which we electrospun dressings. Electrospun dressings, as well those based on hydrogels incorporated compounds, these requirements. manuscript reviews recent used discussing their formation, application, functionalization. The focus presenting hydrogels. In contrast, advancements care have highlighted potential of thermoresponsive dynamic These contain adaptable polymers that offer targeted drug delivery show promise managing various types while addressing infections. way, article intended serve a compendium knowledge researchers, medical practitioners, biomaterials engineers, providing up-to-date information state art, possibilities innovative solutions, challenges area
Language: Английский
Citations
19
European journal of medical research, Journal Year: 2023, Volume and Issue: 28(1)
Published: Nov. 24, 2023
Abstract This paper gives a detailed analysis of nanotechnology's rising involvement in numerous surgical fields. We investigate the use nanotechnology orthopedic surgery, neurosurgery, plastic oncology, heart vascular ophthalmic thoracic and minimally invasive surgery. The details how helps with arthroplasty, chondrogenesis, tissue regeneration, wound healing, more. It also discusses employment nanomaterials implant surfaces, bone grafting, breast implants, among other things. article explores various uses, including stem cell-incorporated nano scaffolds, nano-surgery, hemostasis, nerve nanorobots, diagnostic applications. ethical safety implications using surgery are addressed. future possibilities investigated, pointing to possible route for improved patient outcomes. essay finishes comment on transformational influence applications its promise breakthroughs. Graphical
Language: Английский
Citations
38
Journal of Advanced Ceramics, Journal Year: 2023, Volume and Issue: 12(9), P. 1671 - 1684
Published: July 17, 2023
In bone tissue engineering, scaffolds with excellent mechanical and bioactive properties play prominent roles in space maintaining regeneration, attracting increasingly interests clinical practice. this study, strontium-incorporated β-tricalcium phosphate (β-TCP), named Sr-TCP, bioceramic triply periodic minimal surface (TPMS) structured were successfully fabricated by digital light processing (DLP) based 3D printing technique, achieving high porosity, enhanced strength bioactivity. The Sr-TCP first characterized element distribution, macro- microstructure, properties. Notably, the compressive of reached 1.44 MPa a porosity 80%, bringing great breakthrough to porous scaffolds. Furthermore, also facilitated osteogenic differentiation mouse osteoblastic cell line (MC3T3-E1) cells both gene protein aspects, verified alkaline phosphatase (ALP) activity polymerase chain reaction (PCR) assays. Overall, printed TPMS obtained boosted superior bioactivity at same time, serving as promising approach for regeneration.
Language: Английский
Citations
28
Advanced Fiber Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Aug. 15, 2024
Language: Английский
Citations
11
Advanced Materials Technologies, Journal Year: 2024, Volume and Issue: 9(15)
Published: May 7, 2024
Abstract Controllable and long‐term release remains a great challenge in current drug delivery systems. Benefiting from their efficient loading painless administration, microneedles (MNs) have emerged as promising platform for transdermal delivery, while they often fail to achieve tissue adhesion controllable extended release. Here, 3D printing of an innovative MN patch is presented with succulent‐inspired responsive microstructures light‐controllable capability. The exhibits reversible shrink‐swell volume change behavior response surrounding humidity, which enables sufficient mechanical strength skin penetration under the shrinkage conditions when swollen tissues. Moreover, introduces system, achieved through integration thiolated heparin (Hep‐SH) sustained growth factor graphene oxide (GO) nanosheets controlled via near infrared (NIR) laser irradiation. patches good biocompatibility can promote proliferation, migration, proangiogenesis endothelial cells further demonstrated. Thus, it believed that such flexible be candidates well other related engineering applications.
Language: Английский
Citations
10
Biomacromolecules, Journal Year: 2024, Volume and Issue: 25(4), P. 2243 - 2260
Published: March 25, 2024
Cartilage repair has been a significant challenge in orthopedics that not yet fully resolved. Due to the absence of blood vessels and almost cell-free nature mature cartilage tissue, limited ability resulted socioeconomic pressures. Polysaccharide materials have recently widely used for tissue due their excellent cell loading, biocompatibility, chemical modifiability. They also provide suitable microenvironment regeneration. In this Review, we summarize techniques clinically repair, focusing on polysaccharides, polysaccharides differences between these other materials. addition, engineering strategies an outlook developing next-generation regeneration from polysaccharides. This Review will theoretical guidance polysaccharide-based with clinical applications
Language: Английский
Citations
9
Biomaterials Research, Journal Year: 2025, Volume and Issue: 29
Published: Jan. 1, 2025
Tendon/ligament-bone junctions (T/LBJs) are susceptible to damage during exercise, resulting in anterior cruciate ligament rupture or rotator cuff tear; however, their intricate hierarchical structure hinders self-regeneration. Multiphasic strategies have been explored fuel heterogeneous tissue regeneration and integration. This review summarizes current multiphasic approaches for rejuvenating functional gradients T/LBJ healing. Synthetic, natural, organism-derived materials available vivo validation. Both discrete gradient layouts serve as sources of inspiration organizing specific cues, based on the theories biomaterial topology, biochemistry, mechanobiology, situ delivery therapy, which form interconnected network within design. Novel engineering can be constructed by electrospinning, 3-dimensional printing, bioprinting, textiling, other techniques. Despite these efforts being limited at present stage, scaffolds show great potential precise reproduction native T/LBJs offer promising solutions clinical dilemmas.
Language: Английский
Citations
1
Advanced Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 5, 2025
Abstract Osteoporosis, characterized by low bone mass and high fracture risk, challenges orthopedic implant design. Conventional 3D‐printed Ti6Al4V scaffolds are mechanically robust but suffer from poor regeneration in osteoporotic patients due to stress shielding cellular senescence. In this study, a functionalized “Cell Climbing Frame” is developed, aiming adapt the mechanical microenvironment of osteoporosis, effectively recruit support adhesion growth autologous marrow mesenchymal stem cells (BMSCs), while rejuvenating senescent for improved regeneration. Inspired marine sponges, processing accuracy limitations selective laser melting (SLM) technology broke through innovatively constructing hierarchical porous structure with macropores micropores nested within each other. Results demonstrate that unique scaffold reduces elastic modulus, facilitates blood penetration, enhances cell growth. Further surface functionalization E7 peptides exosomes promotes attraction rejuvenation BMSCs boosts migration, proliferation, osteogenic differentiation vitro. vivo, accelerates repair rats, delaying surrounding loss, enabling multi‐stage osseointegration. This innovation advances regenerative implants repair.
Language: Английский
Citations
1